Hcv genotype 1 - PowerPoint PPT Presentation


Landlord Seminar Overview and Programs in Los Angeles

This content provides information about an upcoming landlord seminar on May 11, 2023, focusing on topics such as Fair Housing, Violence Against Women Act (VAWA), Emergency Housing Voucher Program (EHV), and the Housing Choice Voucher (HCV) Program in Los Angeles. It covers details on program overvie

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Guidelines for Treating Chronic Hepatitis C Virus Infection

Clinical guidelines provide evidence-based recommendations for treating and curing chronic HCV infection in adults to improve treatment rates, reduce morbidity and mortality, and support the New York State Hepatitis C Elimination Plan. Recommendations include considerations in HCV treatment initiati

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HCV Utilization Webinar

Today's webinar covers topics such as 2023 reconciliation, 2024 funding projections, PIC data cleanup, special purpose voucher updates, and more. Presenters from the US Department of Housing & Urban Development share important information and reminders regarding VMS data submission deadlines, eVMS u

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LiveRx Study - Eradicating Hepatitis C in Alberta

LiveRx Study aims to evaluate the impact of a collaborative program involving community pharmacies and organizations in treating HCV in Alberta. By leveraging pharmacist-led interventions, the initiative focuses on increasing HCV screening, diagnosis, and linkage to care, ultimately aiming to eradic

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Implementing a Model to Combat the Syndemic at Cass Lake IHS

This presentation outlines the initiative to address the syndemic at Cass Lake IHS, focusing on Hepatitis C and harm reduction services. It discusses the background of Hepatitis C, the challenges faced in previous treatments, and the new pharmacist-run HCV clinic model. The aim is to educate on the

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Investigating Human Papillomavirus Genomes in Cervical Neoplasms

This project focuses on studying the Human Papillomavirus (HPV) genome's association with disease progression and treatment response in cervical neoplasms and cancer. The research aims to genotype high-risk HPVs in healthy and diseased cervix, identify prevalent genotypes, detect genotype drift, cha

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Understanding Transmission of Infectious Diseases in Epidemiology

Exploring the various modes of transmission of infectious diseases, this content delves into how blood, internal fluids, genital fluids, droplets, coughing, airborne particles, and contact can spread pathogens like HIV, HBV, HCV, and more. It discusses the mechanisms and risks associated with each m

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Indigenous and Strengths-Based Approaches in Addressing Opioid Misuse

Explore the application of Indigenous and strengths-based approaches to tackle opioid misuse, focusing on harm reduction, intervention models, key concepts of HIV and HCV transmission, and value systems that guide work in communities. Gain insights into the value systems shaping attitudes towards su

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Understanding the Housing Choice Voucher (HCV) Homeownership Program

The Housing Choice Voucher (HCV) Homeownership Program helps low-income, first-time homebuyers by providing monthly housing assistance payments. This presentation covers key aspects such as program overview, steps to develop the program, operations, counseling, eligible housing, inspections, financi

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Best Practices in Waitlist Management Webinar

This webinar focuses on best practices in waitlist management for the HCV program. It covers topics such as program updates, waitlist rules, regulations, and best practices from various housing authorities. The content discusses the purpose of the waiting list, opening the waiting list, conducting o

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Blood-Borne Disease Hazards in Healthcare Settings

Healthcare workers face risks of exposure to bloodborne pathogens like HIV, HBV, and HCV. This training module covers sources and routes of exposure, emphasizing the importance of universal precautions. Specific focus is given to Hepatitis B and C viruses, their impact on the liver, transmission met

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Advances in Hepatitis C Treatment for HIV-Infected Patients: A Comprehensive Overview

Explore the latest advancements in the treatment of Hepatitis C virus (HCV) in HIV-infected individuals through a detailed presentation by Dr. Kara W. Chew. Learn about the initial evaluation for HCV, treatment options for different genotypes, management of advanced fibrosis, recommended approaches

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Supporting Harm Reduction and Health Care in Prisons

PASAN (Prisoners with HIV/AIDS Support Action Network) in Ontario exclusively works with prisoners and ex-prisoners to provide support, education, and advocacy related to HIV/HCV and harm reduction. They aim to ensure healthcare access and continuity of care for prisoners living with HIV/HCV, combat

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Genotype-Directed Dosing for Efavirenz in Children Study

The study focuses on genotype-directed dosing of Efavirenz in children with HIV, aiming to optimize treatment options and dosages based on genetic factors. It explores the challenges in treating children with HIV, especially in resource-limited settings, and discusses the impact of genetic variation

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Understanding Genotype and Phenotype in Hereditary Traits

Exploring simple heredity through predicting and modeling phenotypes of Crazy Creatures, students are tasked with contrasting genotype and phenotype. The Crazy Traits lab data table is essential for recording alleles and genotypes, aiding in determining phenotypes for 14 different traits. By complet

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Decline of Hepatitis C in England: 2022 Report Highlights

The 2022 report on Hepatitis C in England shows a continued decline in the prevalence of chronic HCV infection, with around 81,000 individuals estimated to be affected in 2020. The report also highlights the distribution of infections among individuals with different drug injecting histories. Data f

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HCV Webinar Highlights & Program Updates - April 18, 2024

Today's webinar covers updates on 2024 funding, income protections, and program resources. Details include new funding timelines, highlights of the 2024 appropriations, combating source of income discrimination, and more. Stay informed and engaged with the latest developments in the HCV program.

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Understanding Genotype and Phenotype: The Genetic Basis of Organism Variation

Genotype determines the genetic makeup of an organism, while phenotype encompasses its observable traits. Johannsen's theory states that phenotype is a result of genotype, which remains constant throughout life. The concept of phenocopy refers to mimicking another phenotype without altering the geno

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Hepatitis C Screening Recommendations for Adults (2017)

The Canadian Task Force on Preventive Health Care (CTFPHC) released recommendations on Hepatitis C screening for adults in 2017. The guidelines provide an overview of screening methods, key findings, implementation considerations, and conclusions. Those at higher risk for HCV in Canada include indiv

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Maternal Effect on Shell Coiling in Snails

Maternal effects play a crucial role in determining the coiling direction of snail shells. The maternal inheritance of organelle genes controls certain traits in offspring, with the direction of shell coiling being a classic phenotype exhibiting maternal effects. The genotype of the female parent de

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Risk of HCV Reinfection Among HIV/HCV Co-Infected Individuals in Europe

In the absence of an HCV vaccine, individuals cured of HCV are still at risk of reinfection, particularly among HIV-co-infected populations. This study aims to examine the risk of reinfection within 2 years of achieving sustained virological response in Europe. Regional differences, treatment regime

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Exploring Protein Modeling in Sickle Cell Genotype

Dive into the world of protein modeling to understand why some individuals with the sickle cell genotype remain asymptomatic. Explore amino acid sequences, build typical and sickle cell protein segments, and visually represent the changes in protein structure. Hands-on instructions guide you through

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Comparison of Simeprevir vs. Telaprevir in HCV Genotype 1 Non-Responders

The ATTAIN study compared simeprevir and telaprevir in previous non-responders with genotype 1 HCV. The study included 379 patients with simeprevir and 384 with telaprevir, focusing on SVR12 as the primary endpoint. Baseline characteristics, treatment regimens, patient disposition, and virologic out

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Overview of Hepatitis C Epidemiology in Ghana by Dr. Fred Stephen Sarfo

Dr. Fred Stephen Sarfo's research on Hepatitis C in Ghana reveals a notable sero-prevalence of the virus across various populations such as blood donors, prisons inmates, and more. The studies show varying HCV antibody frequencies, highlighting the need for continued surveillance and targeted interv

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Star-AI for Genetic Data Analysis: Incorporating Knowledge in Statistical Modeling

Knowledge-based approaches are crucial in genetic data analysis to enhance the accuracy and scope of genome-wide association studies (GWAS). Stochastic Relational AI (Star-AI) offers a solution by leveraging probability theory and First Order Logic to capture complex genetic interactions. By integra

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C-EDGE.TN Study: Grazoprevir/Elbasvir in Genotype 1, 4, or 6 - Treatment for HCV Infection

The C-EDGE.TN Study evaluated the efficacy of grazoprevir/elbasvir treatment in patients with HCV infection, specifically genotype 1, 4, or 6. The study included 316 patients and aimed to achieve SVR12 rates superior to historical standards. The treatment was well-tolerated, with high SVR12 rates ac

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Efficacy of Ombitasvir-Paritaprevir-Ritonavir and Dasabuvir with Ribavirin in Liver Transplant Recipients with Recurrent HCV GT1

The CORAL-I trial evaluated the safety and efficacy of the 3D regimen (ombitasvir-paritaprevir-ritonavir + dasabuvir) combined with ribavirin for 24 weeks in liver transplant recipients with recurrent HCV genotype 1. The study included treatment-naive individuals after transplantation, with specific

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Healthcare Utilization in Quebec Immigrants and Non-Immigrants with Chronic Hepatitis C Infection

This study, supervised by Dr. Christina Greenaway, aims to estimate and compare healthcare utilization in Quebec immigrants and non-immigrants diagnosed with chronic Hepatitis C infection. The research seeks to identify predictors of all-cause and liver-related healthcare utilization. With rising he

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Study on Grazoprevir and Elbasvir in Genotype 1 with Child-Pugh B Cirrhosis

The C-SALT study evaluated the efficacy of grazoprevir and elbasvir in patients with genotype 1 chronic HCV infection and Child-Pugh B cirrhosis. The primary endpoint was achieving sustained virologic response at 12 weeks. The study included treatment-naive and pre-treated patients with IFN-based re

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Daclatasvir + Sofosbuvir + Ribavirin in HCV GT-3 Advanced Liver Disease: ALLY-3+ Trial

The ALLY-3+ Trial investigates the efficacy of daclatasvir, sofosbuvir, and ribavirin in patients with chronic HCV GT-3 and advanced liver disease. This Phase 3 study compared 12 versus 16 weeks of treatment in treatment-naive or experienced individuals. Results showed promising SVR12 rates and favo

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Effectiveness of Daclatasvir and Sofosbuvir in HCV Genotype 3: Insights from ALLY-3 Study

Study on the efficacy of Daclatasvir and Sofosbuvir in treating Hepatitis C Virus (HCV) Genotype 3, involving treatment-naive and treatment-experienced patients. The Phase 3 trial showcased promising results in achieving SVR12, with detailed patient characteristics, drug dosing, and baseline charact

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Therapeutic Trials in HIV/HCV Coinfection: ION-4, Ally-2, and Viroteam 2015

In the study of therapeutic trials in HIV/HCV coinfection between 2014-2015, notable trials included ION-4 with LDV/SOF treatment for 12 weeks in HCV/HIV co-infection patients, showing high SVR rates in both treatment-naive and experienced patients. Another trial, Ally-2, involved Daclatasvir and So

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Challenges in the Management and Treatment of HIV/Hepatitis C Virus Coinfection

This presentation by Dr. Ricardo A. Franco focuses on the challenges faced in managing and treating patients with HIV/Hepatitis C virus coinfection. It discusses the burden of HCV mono-infection and HIV/HCV co-infection, the impact of HIV co-infection on survival in HCV-related cirrhosis, and the ro

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C-EDGE.CO-STAR: Grazoprevir/Elbasvir for HCV Infected Drug Users on Opioid Replacement Therapy

A study on the effectiveness of grazoprevir/elbasvir in treating HCV-infected individuals on opioid replacement therapy. The study aimed to achieve SVR12 with immediate treatment and compared results to deferred treatment. The primary endpoint SVR12 was achieved in a high percentage of patients on i

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Study on Elbasvir/Grazoprevir with or without Ribavirin in HCV Patients

The C-EDGE.experienced Study investigated the use of Elbasvir/Grazoprevir with or without Ribavirin in patients who failed prior therapy with PEG-IFN and Ribavirin. The study had 105 participants and aimed to achieve an SVR12 rate of over 95%. Results showed high SVR12 rates in both treatment arms,

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Comparison of SOF+RBV vs PEG-IFN-2a+RBV for HCV Genotype 2 and 3 Treatment

FISSION Study compared the efficacy of SOF+RBV and PEG-IFN-2a+RBV for HCV genotypes 2 and 3 in treatment-naive patients with chronic HCV infection. The study included 256 participants in the SOF+RBV group and 243 in the PEG-IFN-2a+RBV group. The primary objective was to determine the non-inferiority

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Simeprevir Combination Therapy in Treatment-Naïve HCV Genotype 1 Patients: QUEST-1 Trial Results

The QUEST-1 trial evaluated the efficacy and safety of simeprevir in combination with peginterferon and ribavirin versus peginterferon and ribavirin alone in treatment-naïve patients with chronic HCV genotype 1 infection. The study showed a significantly higher proportion of patients achieving sust

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Simeprevir Treatment in HCV Genotype 1: ASPIRE Trial Results

The ASPIRE trial evaluated simeprevir treatment in patients with treatment-experienced chronic HCV genotype 1 infection. The study design included different dosing regimens of simeprevir with peginterferon and ribavirin, compared to placebo. Results showed varying sustained virologic response rates

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Understanding Genotype and Phenotype in Genetics

Genotype refers to the genetic code responsible for specific traits, while phenotype is the outward appearance and characteristics of an organism. Traits can be dominant or recessive, with alleles representing the possible choices for a characteristic. Genotypes consist of two letters, one from each

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Study on GZR, EBR, and MK-3682 for Chronic HCV Infection

The C-CREST study, Part A, focuses on the Phase II design of GZR, EBR, and MK-3682 treatment for genotypes 1, 2, and 3 in chronic HCV infection. The study includes baseline characteristics, SVR12 endpoint, impact of NS5A RAVs, and treatment outcomes. Results show promising SVR rates with different r

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