Understanding Cardiorenal Syndrome: A Complex Relationship Between the Heart and Kidneys

Cardiorenal Syndrome is a condition where dysfunction in one organ, whether acute or chronic, can lead to dysfunction in the other. This complex relationship involves intricate communication pathways between the heart and kidneys, impacting hemodynamic stability, organ perfusion, and neurohormonal interactions. Treatment involves accurate volume status assessment, aggressive management of volume overload, and optimization of renal perfusion to address underfill or overfill issues.

• Cardiorenal Syndrome
• Heart
• Kidneys
• Hemodynamic Stability
• Organ Perfusion

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1. Cardiorenal Syndrome Renal uitm

2. It is a syndrome! Not a diagnosis. Renal uitm

3. Cardiorenal syndrome definition condition whereby an acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other Renal uitm

4. Relationship is complex! The heart and the kidney communicate with one another through a variety of pathways in an interdependent relationship Renal uitm

5. Relationship is complex! Related image wife Related image Related image girlfriend Renal uitm

6. Relationship is complex! Related image wife Pulmonary-renal syndrome Related image Related image Hepato-renal syndrome girlfriend Renal uitm

7. Neurohormonal relationship BP and Volume The heart and the kidneys are involved in maintaining hemodynamic stability and organ perfusion through an intricate network. Related image Related image Renal uitm

8. Pathophysiology Haemodynamic related Non-haemodynamic related hormonal and immune mediated Renal uitm

9. Pathophysiology underfill or overfill Haemodynamic related Renal uitm

10. Treatment Accurate Assessment of Volume Status Renal/Venous Congestion Aggressive Treatment of Volume Overload Removal of Fluid Accumulation in Third Spaces Diuretics and Diuretic Resistance Ultrafiltration Arterial Underfilling (Renal Hypoperfusion) Avoidance of Arterial Hypotension and Intravascular Underfilling Increasing the Effective Circulatory Volume Optimization of Renal Perfusion Renal uitm

11. Types of CRS Renal uitm

12. Types of CRS Renal uitm

13. RRT in haemodynamically unstable intermittent hybrid continuous HD SLEDD CVVHD SLEDD-f CVVHDF HDF Isolated UF SCUF Renal uitm

14. Types of RRT Conventional HD 300-350 500 4H SLEDD 150-200 200-300 6-8H CRRT 150-180 (2L/h) 33 72H Qb (ml/min) Qd (ml/min) Time UF Variations HDF SLED-F SCUF CVVHD CVVHDF Expensive Multiple inotropes Cardiogenic shock Cost Patients Cheap Fair Stable Sepsis shock Single inotropes Renal uitm

15. Thank you! @ Renal Uitm Renal uitm