Coronary Heart Disease
Coronary heart disease, including its introduction, pathophysiology, types, signs and symptoms, diagnosis, management, and risk factors. It also discusses the epidemiology and complications associated with the disease.
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Understanding Alinity i STAT High Sensitivity Troponin-I for Cardiovascular Diagnosis
Alinity i STAT High Sensitivity Troponin-I is a proprietary assay used in diagnosing myocardial infarction (MI) by quantitatively measuring cardiac troponin I in human plasma. This chemiluminescent microparticle immunoassay (CMIA) aids in the detection of MI, a significant aspect in managing heart d
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Understanding the Natural History of Disease Development and Prevention
The natural history of disease development outlines the progression of a disease in an individual without intervention, from exposure to outcome. Learning objectives include defining prevention terms, understanding disease severity, prevention levels, and intervention measures. Studying disease prog
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Overview of Acute Cholecystitis: Diagnosis, Severity Grading, and Treatment
Acute calculous cholecystitis is a common digestive disease with varying treatment perspectives. The Tokyo Guidelines 2018 provide criteria and severity grading for the diagnosis of acute cholecystitis. Diagnosis involves local and systemic signs of inflammation along with specific imaging findings.
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Principles of Epidemiology: Understanding Disease Occurrence and Surveillance
Epidemiology is the study of disease patterns, factors influencing disease occurrence, and the core functions of surveillance, field investigation, and analytic studies. It involves understanding disease characteristics, natural history, and evaluating the effectiveness of activities to mitigate dis
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Understanding Chronic Kidney Disease: Overview and Diagnosis
Explore the essentials of Chronic Kidney Disease (CKD): its significance, the functioning of kidneys, causes, diagnosis methods, and considerations based on age. Gain insights into CKD stages and learn how to maintain kidney health for a better quality of life.
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Insights into Tyzzer's Disease: An Overview of a Bacterial Infection in Laboratory Animals
Tyzzer's disease is an acute bacterial infection affecting rodents and rabbits, caused by Clostridium piliforme. Discovered in 1917 by Ernest Tyzzer, the disease is characterized by necrotic lesions in the caecal mucosa, liver, and heart. Initially known as Bacillus piliformis, it was later renamed
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Understanding Bluetongue Disease in Sheep, Cattle, and Goats: Causes, Symptoms, and Diagnosis
Bluetongue disease is a viral illness predominantly affecting sheep, with occasional cases in cattle and goats. Transmitted by insect vectors, it can lead to various symptoms such as catarrhal stomatitis, lameness, and reproductive issues. The disease's impact, transmission methods, clinical signs,
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Understanding Real-Time PCR and its Applications
Real-Time PCR, also known as quantitative PCR, is a specialized technique used in molecular biology for gene expression analysis, medical research, disease diagnosis, viral quantification, and more. It enables the real-time visualization and measurement of DNA sequences in a sample, playing a crucia
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Understanding Disease Control and Prevention in Epidemiology
This article discusses disease control processes in epidemiology, including reducing disease incidence, duration, and transmission. It covers public policy interventions, elimination, eradication, and extinction of infectious agents. It also highlights preventable causes of disease and different lev
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Retinal Imaging for Alzheimer's Disease: A Comprehensive Review
The increasing prevalence of Alzheimer's disease (AD) necessitates sensitive screening technologies for early detection. Retinal imaging emerges as a promising tool due to its non-invasive nature, cost-effectiveness, and potential as a window to the brain. This review explores the utility of retinal
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28 Day Faster Diagnosis Standard in Cancer Services
The 28 Day Faster Diagnosis Standard focuses on timely referral to definitive diagnosis for suspected cancer patients, enabling prompt treatment initiation or providing peace of mind. Key principles include starting the clock upon receipt of referral and ending it upon diagnosis communication or tre
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Neonatal Vomiting: Causes, Diagnosis, and Differential Diagnosis
Neonatal vomiting can be a concern when presenting with bile-stained or blood-stained vomit, projectile vomiting, or associated with weight loss and failure to grow. Various non-surgical and surgical conditions like Pyloric Stenosis can lead to vomiting in neonates. Common causes include Mid-gut vol
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Laboratory Diagnosis of Fungal Infections: Specimen Collection and Transport
In the laboratory diagnosis of fungal infections, proper collection and transportation of specimens are crucial for accurate diagnosis and treatment. Different sites and types of specimens require specific collection techniques to avoid contamination and ensure viability. From superficial to systemi
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Understanding Tetanus: Causes, Symptoms, and Diagnosis
Tetanus, also known as Locked Jaw or Saw Horse disease, is a highly fatal condition in domestic animals caused by the neurotoxin produced by Clostridium tetani. The disease is characterized by hyperaesthesia, tetany, and convulsions. Transmission occurs through contaminated soil, typically from hors
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Update on Kidney Disease in HIV for Ryan White Providers
This update provides valuable insights into kidney disease in HIV patients, focusing on diagnosis caveats, acute kidney injury, different HIV-associated nephropathies, and the changing spectrum of chronic kidney disease. It emphasizes the importance of accurate diagnosis and management, considering
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Chronic Obstructive Pulmonary Disease (COPD) in Horses: A Veterinarian's Perspective
Chronic Obstructive Pulmonary Disease (COPD) in horses is a respiratory condition caused by hypersensitivity reactions to allergens, viral infections, or bronchopneumonia. This chronic respiratory disease leads to decreased work performance, chronic coughing, abnormal lung sounds, and cardiac dysfun
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Comprehensive Overview of Parotid Tumor Diagnosis and Management
This comprehensive guide covers the diagnosis and management of parotid tumors, including anatomy, differential diagnosis, and management strategies. It discusses the approach to evaluating patients with neck lumps, differential diagnoses to consider, and the management techniques for both benign an
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Understanding Fowl Pox in Avian Species: Causes, Symptoms, and Diagnosis
Fowl Pox, caused by Avipoxvirus, is a contagious disease in birds characterized by wart-like nodules and diphtheritic membranes in the throat and mouth. It has multiple forms, including dry pox, wet pox, and coryza-like form, with varying clinical signs. The disease spreads through mosquitoes, bitin
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Radiology Case Presentation: Differential Diagnosis of Large Posterior Fossa Mass in 25-Year-Old Male
25-year-old male with persistent headaches and neck pain presents with worsening symptoms. Differential diagnosis includes primary brain tumor, pyogenic abscess, pilocytic astrocytoma, medulloblastoma, and other possibilities. Neurocysticercosis, a parasitic disease caused by T. solium, endemic in c
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Understanding Trypanosomiases: African Sleeping Sickness and Chagas Disease
Trypanosomiases are parasitic diseases caused by Trypanosoma parasites, with African sleeping sickness and Chagas disease being the two main types affecting humans. African sleeping sickness, transmitted by the tsetse fly, can lead to chronic or acute illness and is primarily found in Africa. The di
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Screening for Peripheral Vascular Disease in Patients with Coronary Artery Disease
Patients with coronary artery disease should be screened for peripheral vascular disease as it is a frequent integrator of global cardiovascular risk. The association of atherosclerosis in various arterial diseases highlights the importance of identifying multisite artery disease. The prevalence and
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Appropriate Use Criteria for Lumbar Puncture in Alzheimer's Disease Diagnosis
Clinicians traditionally diagnose Alzheimer's Disease (AD) based on clinical criteria, but cerebrospinal fluid (CSF) AD biomarkers offer more reliable detection earlier in the disease course. This article discusses the criteria for lumbar puncture and CSF analysis in the diagnosis of AD, highlightin
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Human Disease Symptom Network: Understanding Disease Relationships Through Symptoms and Genes
The Human Disease Symptom Network (HSDN) is constructed using a large-scale medical bibliographic records database to form a network of human diseases based on symptom similarities. By integrating disease-gene associations and protein-protein interaction data, correlations between symptom similarity
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Understanding Plant Pathology: Reproduction and Classification of Bacteria
This course on Fundamentals of Plant Pathology, led by Mr. Vikash Kumar, covers essential topics such as disease identification, pathogen nature, disease management strategies, pathogen classification, and plant disease diagnosis. It delves into the reproduction and classification of plant pathogeni
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Understanding Bacterial Diseases of Fish: Columnaris Disease Overview
Columnaris disease, also known as Saddleback disease, is a common bacterial infection in fish that is often brought about by poor handling and high stress levels. This disease manifests as tail and fin rot, leading to rapid fish mortality. The causative organism, Cytophaga (formerly Flexibacter), is
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Differential Diagnosis of Ascites in a 50-Year-Old Man with Liver Disease
Ascites, jaundice, and confusion in a 50-year-old man raise concerns about liver disease. Differential diagnosis includes cirrhosis, malignancy, alcoholic liver disease, and biliary obstruction. Physical examination findings such as spider naevi, hepatomegaly, and asterixis help narrow down the poss
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Understanding Lyme Disease: Symptoms, Diagnosis, and Treatment Options
Lyme disease is an infectious inflammatory disease caused by Borrelia burgdorferi and spread by tick bites. It presents with a range of symptoms, including fever, headache, fatigue, and a characteristic erythema migrans rash. Prompt diagnosis and treatment are essential to prevent complications such
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Understanding Alzheimer's Disease: Facts, Stages, and Impact
Alzheimer's Disease, first discovered in 1906, is a progressive brain condition that affects memory and cognitive function. It is the seventh leading cause of death in the U.S., with significant economic costs and a global impact. Risk factors include age, low mental ability in early life, head inju
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Understanding Fowl Typhoid in Domestic Birds
Fowl Typhoid is a septicemic disease affecting domestic birds, characterized by acute and chronic phases, enlarged spleen, bronzy colored liver, and diarrhea. It is caused by Salmonella gallinarum and primarily affects young and adult chickens. The disease has a short incubation period of 4-5 days,
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Understanding Zoonotic Hepatitis A Virus Infections
Zoonotic hepatitis A virus infections primarily affect humans and nonhuman primates, with transmission occurring through fecal-oral route. This article delves into the reservoir, mode of transmission, clinical signs, and diagnosis of hepatitis A, shedding light on its impact on both species. Nonhuma
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Financial Impact of Cold Agglutinin Screen for Diagnosis of Cold Agglutinin Disease
Cold agglutinin disease, a rare form of autoimmune hemolytic anemia, accounts for 15% of AIHA cases. Implementing a cold agglutinin screen for diagnosis can have significant financial implications in healthcare costs. This condition is characterized by the presence of cold agglutinins, primarily IgM
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Decoding Genetics: Insights from Alzheimer's Disease Symposium to Type 2 Diabetes Study
Explore the latest findings from the Alzheimer's Disease Genetics Symposium 2019 on disease mechanisms, drug targets, and genetic pathways. Dive into the progress made by the Alzheimer's Disease Genetics Consortium over the past decade. Transition to a Genome-Wide Association Study uncovering suscep
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HIV Diagnosis Trends in Ireland (November 2018)
The HIV diagnosis rate in Ireland has shown stability with some fluctuations between 2015 and 2017. There were increases and decreases in diagnosis rates among males and females, with notable trends in different age groups. Diagnoses among men who have sex with men slightly decreased, while there wa
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Liver Disease Burden in Tower Hamlets
Dr. Somen Banerjee, Director of Public Health in London Borough Tower Hamlets, highlights the concerning liver disease mortality rates in the area, with high incidence of cirrhosis, cancer, and hepatitis B and C. The data reveals a significant burden of liver diseases such as Non-Alcoholic Fatty Liv
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Understanding Inflammatory Bowel Disease: Crohn's Disease and Ulcerative Colitis
Inflammatory Bowel Disease (IBD) encompasses Crohn's disease (CD) and ulcerative colitis (UC), chronic conditions with immunologic basis. This article delves into the epidemiology, pathophysiology, and differences between CD and UC, highlighting clinical features, pathology, and complications like a
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Understanding Perthes Disease in Pediatric Patients
Perthes disease, also known as Legg-Calve-Perthes disease, is a common pediatric disorder affecting the blood supply to the rounded head of the femur. It typically affects male children aged 3-10 years old and presents with symptoms such as limping, pain, and stiffness in the hip area. The disease p
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Insights from DMD Early Diagnosis Questionnaire - January & February 2016
Detailed findings from a questionnaire on Duchenne Muscular Dystrophy (DMD) early diagnosis in various countries: average age of DMD diagnosis, medical programs for young children, first person to detect issues, duration between concerns and diagnosis, diagnosis makers, parental information receptio
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Understanding Brucellosis: Causes, Symptoms, Diagnosis, and Treatment
Brucellosis, also known as Undulant Fever or Malta Fever, is a zoonotic disease caused by Brucella spp. Learn about its etiology, transmission, manifestations, diagnosis, treatment, and preventive aspects. Discover the history of Brucellosis and populations at risk. Explore the epidemiology, includi
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Ultrastructural Alterations of Renal Tissue in a Male Patient with Fabry's Disease
Fabry's disease is a rare X-linked lipid storage disorder characterized by deficient lysosomal alpha-galactosidase A activity. This condition primarily affects males, leading to chronic kidney disease and progression to end-stage renal disease. Kidney involvement is a critical aspect, and high doses
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