Practical Guide to Pharmaceutics Experiments by Mr. Nilesh A. Shinde
This practical guide covers Experiment No. 9 on preparing Magnesium Hydroxide Mixture, including ingredients, procedure, and the definition of pharmaceutical mixtures in pharmaceutics. It provides detailed steps for creating the mixture, along with the characteristics and storage instructions for Calamine Lotion.
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PHARMACEUTICS PRACTICAL By :- Mr. Nilesh A. Shinde
EXP. NO. - 9 Magnesium hydroxide mixture
PHARMACEUTICS Ingredients Qty. given for 100 ml. Qty. required For ----- ml Magnesium sulphate 4.75 g ------ ml Sodium hydroxide 1.5 g ------- g Light 5.25 g ----g magnesium oxide chloroform 0.25g ----- ml Purified 100 ml ------ml water q.s. to produce
MIXTURE Definition Pharmaceutical mixtures are liquid oral preparation consisting of one or more medicaments dissolved, suspended or diffused an aqueous vehicle. They are usually freshly or recently prepared and are used fairly quickly, usually within a month for short term therapy like cough, diarrhea, constipation etc.
PROCEDURE Dissolve sodium hydroxide in 15 ml water add light mag. Oxide mix to smooth cream Add sufficient purified water to make 25 ml Pour this suspension in a thin stream in to solution of magnesium sulphate in 25 ml of purified water Stir continuously allow precipitate to subside remove clear liquid ,transfer residue to calico strainer Wash until washing gives slight reaction for sulphate
mix this precipitate [ magnesium hydroxide] with purified water Add chloroform water and adjust final volume to 100 ml with purified water
CALAMINE LOTION Container narrow mouth glass bottle Storage -Store in well closed container Other name milk of magnesia Use laxative , antacid https://youtu.be/1sDN9KHqj_k
