Understanding General Urine Examination

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General Urine Examination involves analyzing waste products, collection of urine specimens, factors affecting urine amount, preservation methods, physical examination characteristics like color and transparency, specific gravity, odor, and chemical properties including pH, protein, glucose levels. It aims to assess hydration levels, kidney function, and detect potential health issues such as diabetes or kidney disease.


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  1. General Urine Examination

  2. Waste products: Organic: Uric acid Creatinine Urea Inorganic: Sulphates Phosphates Chloride Ammonia

  3. Collection of urine specimen Random urine specimen First morning urine specimen 24-hour urine specimen

  4. Factors affect amount of urine: Normal daily urine output is 800-2000 ml Amount of fluid intake Water lost in perspiration, respiration and bowel activity Diarrhea Daytime urine output is two to four times greater than nighttime output.

  5. Preservation of urine specimen Refrigeration Addition of preservatives: Hydrochloric acid Boric acid Glacial acetic acid formaldehyde

  6. Physical examination: Color: Straw, pale yellow, light yellow, yellow, dark yellow and amber.

  7. Transparensy: Clear, hazy, cloudy, turbid and milky.

  8. Specific gravity: Normal urine specific gravity is 1.003-1.035 Odor: Normal urine has inoffensive odor Volume: Fluid intake, sodium and urea excreted, perspiration, respiration cardiovascular and renal function.

  9. Chemical properties:

  10. pH: Normal urine pH is 4.6-8.0 Affected by acidosis and alkalosis. Protein: Normal urine contain no proteins (albumin) If present it is called proteinuria Glucose: Normal urine contain no glucose If present it is called glucosuria (diabetes)

  11. Ketones: Normal urine contain no ketones. If present it is called ketonuria Urobilinogen: Normal urine contain low concentration of it. Bilirubin: It is not present in normal urine.

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