nanotheratics n1 project
The Nanotheranostics u2013 NT1 project concerns the treatment of skin cancer using plasmonic thermal phototherapy, which activates surface plasmons to generate hyperthermia. The product is a class 3 medical device made of gold nanoparticles designed
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The Nanotheranostics NT1 project www.torskal.com
What is the Nanotheranostics NT1 project? The Nanotheranostics NT1 project concerns the treatment of skin cancer using plasmonic thermal phototherapy, which activates surface plasmons to generate hyperthermia. The product is a class 3 medical device made of gold nanoparticles designed using green chemistry, and clinical investigations are due to begin shortly. www.torskal.com
Need for Innovative Treatment Challenges with Current Treatments: Surgery leaves scars and disfiguration. Melanoma requires immediate intervention. Chemotherapy and radiation cause side effects. Solution: Photothermal Therapy (PTT) using Gold Nanoparticles Targeted treatment with minimal side effects. Selective tumor destruction without damaging healthy tissue. www.torskal.com
How Photothermal Therapy (PTT) Works? Mechanism: Uses light-sensitive gold nanoparticles (AuNPs). Near-Infrared (NIR) laser activates gold nanoparticles. Local heat (7 C increase) induces tumor cell death. Advantages: Minimally invasive. Reduces side effects compared to chemotherapy/radiation. Selective targeting ensures healthy tissues remain unaffected. www.torskal.com
The Green Chemistry Approach Green Synthesis of Gold Nanoparticles Uses Hubertia ambavilla, an endemic plant from R union Island. No toxic chemicals involved. Patented process for eco-friendly nanoparticle synthesis. Why Gold Nanoparticles? Biocompatible and non-toxic. Easily internalized by cancer cells. Highly efficient in converting light to heat. www.torskal.com
NT1 Clinical & Preclinical Validation Preclinical Studies Results: No toxicity observed at any level. Effective anti-tumor activity in vitro and in vivo. Preferential internalization into cancer cells. Cells die via apoptosis (not necrosis) reduces inflammation. Current Status: Clinical trials starting soon. Systemic and local administration optimized. www.torskal.com
Project Funding & Collaborations Co-financed by: European Union & R union Region (FEDER 1.15, 1.16). MESR (CIR) & BPI France (recoverable advance). Postdoctoral research supported under the same program. Torskal Pioneering Green Nanomedicine. www.torskal.com
Conclusion & Future Outlook NT1 A Revolutionary Step in Skin Cancer Therapy One-time injection therapy. Fewer side effects than traditional treatments. Sustainable and eco-friendly nanotechnology. Contact Information: Website: www.torskal.com Email: contact@torskal.com Address: 2 rue Maxime Rivi re, Sainte Clotilde, 97490, La R union, France
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