Enhancing Cognitive Performance through Gut Microbiome Targeting
•
Main issues
Partners
Product
Develop targeted inventions (pre- and probiotic) to improve cognitive performance
Purpose
1.
Characterisation of cognitive performance, gut microbiome and physiological responses to high
intensity, high stress situations
2.
Targeted
isolation of key microorganisms associated with improved cognitive performance
3.
Use microbial isolates to characterise the mechanisms and host responses that influence
cognitive performance
P
r
o
j
e
c
t
D
e
s
c
r
i
p
t
i
o
n
P
r
o
j
e
c
t
:
T
e
a
m
C
o
g
n
o
b
i
o
m
e
Human Performance Projects
Human Performance Projects
Human Performance Projects
Human Performance Projects
Main issues
What we have learnt so far?
What does that mean for ADF capabilities?
•
Identifying the pathways that would facilitate manipulation of gut microbiota to enhance
cognitive performance.
•
Potential to develop “pill” based enhancer.
P
a
t
h
t
o
I
m
p
a
c
t
P
r
o
j
e
c
t
:
T
e
a
m
C
o
g
n
o
b
i
o
m
e
•
Cognition is now recognised to be influenced by factors outside the CNS.
•
Cognitive impairment exists in numerous disease states, particularly diseases involving gut
microbiome.
•
Available evidence suggests that gut microbiota is linked to cognitive performance.
•
Multiple pathways can link microbiome to cognitive function.
•
Limited studies to identify precise mechanisms and pathways.
(Tooley, 2021)
Human Performance Projects
Human Performance Projects
Main issues
T
h
e
S
c
i
e
n
c
e
P
r
o
j
e
c
t
:
T
e
a
m
C
o
g
n
o
b
i
o
m
e
Provisional approval
Meta’omic microbiome
analysis
Microbial Biobank
Immune
phenotyping
T
h
e
S
c
i
e
n
c
e
P
r
o
j
e
c
t
:
T
e
a
m
C
o
g
n
o
b
i
o
m
e
Human Performance Projects
Human Performance Projects
Diet and cognitive
survey analysis
5
A
c
k
n
o
w
l
e
d
g
m
e
n
t
s
Associate Professor
Ami Eidels,
Psychology
Professor
Scott Brown,
Psychology
Professor Simon Keely,
Immunology and
Microbiology
Laureate Professor
Nicholas Talley,
Gastroenterology
Dr Emily Hoedt,
Research Fellow
Microbiology
Dr Kerith Duncanson,
Research Fellow,
Dietetics
Kirsten Swan
Project Manager
Sophie Fowler,
PhD Student
Laura Dowling,
PhD Student
University of Newcastle
Queensland University of Technology
Professor
Gene Tyson,
Bioinformatics
Professor
Ottmar Lipp,
Psychology
Associate Professor
Yi-Chin Toh,
Immunology
Associate Professor
Tony Kenna,
Immunology
Microba Life Sciences
Dr Paraic O Cuiv,
Microbiologist
Dr Lutz Krause,
Biostatistics
Dr Kylie Ellis,
Head of Research
Partnerships
Professor
Robert
Speight,
Microbiology
Swinburne University of Technology
Associate Professor
Matthew Cooke,
Nutrition
Katherine Barlow,
PhD Student
DSTG
Dr Katie Tooley
Senior Human Performance Scientist,
Cognition & Microbiome
Dr David Crone
Group Leader,
Cognition and Behaviour
Dr James Volmer,
Research Fellow,
Microbiology
Dr Peter Sternes,
Research Fellow,
Bioinformatics
Dr Alexander Thorpe,
Research Fellow
Psychology
Nicole Simm,
Phd Student
Explore cognitive performance, gut microbiome, and physiological responses in high-stress scenarios. Develop targeted inventions like pre- and probiotics for improved cognitive performance.
Download Presentation
Please find below an Image/Link to download the presentation.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author. Download presentation by click this link. If you encounter any issues during the download, it is possible that the publisher has removed the file from their server.
E N D
Presentation Transcript
Human Performance Projects Project Description Project: Team Cognobiome Partners Main issues Purpose 1. Characterisation of cognitive performance, gut microbiome and physiological responses to high intensity, high stress situations 2. Targetedisolation of key microorganisms associated with improved cognitive performance 3. Use microbial isolates to characterise the mechanisms and host responses that influence cognitive performance Product Develop targeted inventions (pre- and probiotic) to improve cognitive performance
Human Performance Projects Path to Impact Project: Team Cognobiome Main issues What we have learnt so far? Cognition is now recognised to be influenced by factors outside the CNS. Cognitive impairment exists in numerous disease states, particularly diseases involving gut microbiome. Available evidence suggests that gut microbiota is linked to cognitive performance. Multiple pathways can link microbiome to cognitive function. Limited studies to identify precise mechanisms and pathways. (Tooley, 2021) What does that mean for ADF capabilities? Identifying the pathways that would facilitate manipulation of gut microbiota to enhance cognitive performance. Potential to develop pill based enhancer.
Human Performance Projects The Science Project: Team Cognobiome Main issues Provisional approval Biological Specimen Collection Diet and Health Assessment Cognitive Testing
Human Performance Projects The Science Project: Team Cognobiome Microbial Biobank Immune phenotyping Meta omic microbiome analysis Diet and cognitive survey analysis
Acknowledgments University of Newcastle Laureate Professor Nicholas Talley, Gastroenterology Queensland University of Technology Professor Simon Keely, Immunology and Microbiology Dr Emily Hoedt, Research Fellow Microbiology Associate Professor Ami Eidels, Psychology Laura Dowling, PhD Student Nicole Simm, Phd Student Kirsten Swan Project Manager Dr Kerith Duncanson, Research Fellow, Dietetics Dr Alexander Thorpe, Research Fellow Psychology Professor Scott Brown, Psychology Sophie Fowler, PhD Student Professor Gene Tyson, Bioinformatics Professor Robert Speight, Microbiology Dr James Volmer, Research Fellow, Microbiology Dr Peter Sternes, Research Fellow, Bioinformatics Katherine Barlow, PhD Student Associate Professor Yi-Chin Toh, Immunology Associate Professor Tony Kenna, Immunology Professor Ottmar Lipp, Psychology Microba Life Sciences Dr Lutz Krause, Biostatistics Dr Paraic O Cuiv, Microbiologist Swinburne University of Technology Dr Kylie Ellis, Head of Research Partnerships DSTG Dr Katie Tooley Senior Human Performance Scientist, Cognition & Microbiome Dr David Crone Group Leader, Cognition and Behaviour Associate Professor Matthew Cooke, Nutrition 5
