This prospective, multicentre, randomised clinical trial led by Dr. Tiffany Patterson aims to determine whether direct delivery to a cardiac arrest centre following non-ST elevation out-of-hospital cardiac arrest reduces deaths compared to delivery to the nearest emergency department. Funded by the

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This course covers the basics of systems modeling, discrete-event simulation, and computer systems performance evaluation. Topics include Monte Carlo simulation, probability models, simulation output analysis, queueing theory, and more. Professor Carey Williamson leads the course with a focus on pra

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This UK-wide clinical trial aims to assess the effectiveness of early peripheral norepinephrine infusion in adult patients with septic shock. The study will compare the impact on mortality and other outcomes of targeting a mean arterial pressure (MAP) above 65mmHg within the first 48 hours of admiss

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The U.S. Army Modeling and Simulation Office (AMSO) serves as the lead activity in developing strategy and policy for the Army Modeling and Simulation Enterprise. It focuses on effective governance, resource management, coordination across various community areas, and training the Army Analysis, Mod

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Empagliflozin's impact on cardiovascular and renal events in heart failure with reduced ejection fraction was assessed in the EMPEROR-Reduced trial led by Milton Packer, MD, and Faiez Zannad, MD. The trial, enriched for patients with severe left ventricular dysfunction, randomized participants to em

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Explore the process of simulating clinical trial designs, including traditional and adaptive approaches. Learn how to generate data, conduct analysis, make within-trial decisions, and summarize results using fixed-sample two-arm parallel group trials and group-sequential designs. Dive into methods l

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The UK Mini Mitral Trial compares the outcomes of minimally invasive thoracoscopic-guided right minithoracotomy versus conventional sternotomy for mitral valve repair. The trial aims to determine if physical function improvement post-surgery at 12 weeks is superior in the minimally invasive approach

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Explore the various types of hearings available in the Court Management System, such as Motion Calendar, Special Sets, Calendar Call/Trial, Pre-Trial Conference, and Case Management. Learn how to set up new hearings/events and understand the process of generating trial orders and pre-trial conferenc

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The STRESS-L Trial focuses on reversing septic shock using Landiolol, a beta-blockade treatment. It provides training for non-GCP trained clinicians involved in eligibility review, medical care, and prescribing in the trial. The slides cover key GCP principles, trial agenda, study information, backg

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Simulation studies are often used to evaluate statistical methods and study power, but they can sometimes produce misleading results. This work discusses strategies to assess and improve the quality of simulation studies, drawing on experiences and considerations outlined in relevant literature. A s

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The CLEAR Trial is a 2x2 factorial randomized trial evaluating the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the trial focuses on clinical and c

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ACST-2 is a randomized trial comparing carotid artery stenting (CAS) versus carotid artery surgery (CEA) in asymptomatic patients with severe carotid stenosis. The trial, published in The Lancet in August 2021, involved 3625 patients. While surgery has been shown to reduce stroke rates, modern medic

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The Sixth Amendment guarantees various rights during criminal trials, such as a speedy and public trial, trial by jury, notice of accusations, the right to confront witnesses, and the assistance of counsel. Defendants can opt for a bench trial where the judge decides innocence or guilt. Juries, typi

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Basin Manipulation Simulation Analysis Tool provides a comprehensive solution for managing and analyzing basin data, including tasks like basin manipulation, simulation analysis, case management, and defining simulation time steps. The tool allows for easy data entry, visualization of simulation res

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The CLEAR Trial is a 2x2 factorial randomized trial examining the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the study focuses on exacerbation ma

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NCI-MATCH is a groundbreaking clinical trial aiming to match tumor gene alterations with targeted therapies. The interim analysis results revealed impressive patient enrollment and site participation exceeding expectations. Despite challenges with pausing new patient registrations for the analysis,

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Hands-on simulation training in education provides students with valuable learning experiences by increasing self-reported knowledge and technical proficiency. Simulations help improve students' knowledge, experience, and comfort with challenging procedures in a lower-risk environment, leading to en

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Computer simulation and modeling is essential for conducting studies in various fields. Selecting the right simulation language or package is crucial for accurate results. This involves considering the characteristics of the language, such as random number generation, process transformers, list proc

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Understanding the key components of a clinical trial research protocol is essential for conducting successful studies. This includes identifying session objectives, discussing trial protocol contents, exploring observational study elements, and learning about reporting guidelines. Study objectives f

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Overview of recent talks and discussions at LCWS 2014 in Belgrade, Serbia, focusing on machine protection, simulation codes, instrumentation, and system tests. Topics include beam-loss monitors, dark current measurements, simulation code developments, and beam dynamics studies in linacs. Key speaker

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Enhance your trial skills in family law with a focus on evidence collection, trial strategies, and client examination. Learn best practices for preserving evidence, drafting persuasive statements, and navigating trials confidently. This workshop covers important aspects of evidence collection, such

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Explore the principles and benefits of healthcare simulation, focusing on formative evaluation and constructive feedback to improve learning outcomes. Delve into the role of formative assessment tools, TeamSTEPPS model, and Mayo High Performance Teamwork Scale in simulation scenarios. Discover the s

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Explore the innovative tool nQuery Predict for accurate clinical trial milestone predictions, demonstrated in a webinar hosted by industry experts. Learn about key milestones, adaptive design considerations, enrollment predictions, and the significance of statistical approaches in optimizing trial d

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Exploring the detailed process of civil rights litigation, covering steps from fact gathering to trial preparation and post-trial activities. The visual presentation showcases key elements such as client retention, complaint filing, discovery phases, trial preparation, and post-trial procedures like

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Simulation competition where students portray attorneys and witnesses in a civil jury trial based on the case of professional writer Riley Winter suing an online magazine for wrongful termination due to age discrimination. Judges preside over the trial, score performances, and provide feedback, focu

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In this competition, students simulate a criminal jury trial where they take on roles as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves State v. Sinclair, focusing on the murder trial of Skyler Sinclair, a suspect in the death of an undercover officer

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Simulation of a criminal jury trial where students act as attorneys and witnesses in a fictitious jurisdiction with its own laws. This year's case involves the attempted murder of a spouse. Judges preside, score, provide feedback, and reach a verdict in panels. The trial follows a structured outline

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Simulation study on beam polarization for the Circular Electron Positron Collider (CEPC) using the PTC Poly- morphic Tracking Code. The study includes orbital and spin tracking, equilibrium polarization calculation, and Monte-Carlo simulation of depolarization rate. Comparison with other Monte-Carlo

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AIRWAYS-3 is a multi-centre, open-label, randomized trial evaluating the clinical and cost effectiveness of a supraglottic airway (SGA) versus tracheal intubation during in-hospital cardiac arrest (IHCA). The trial aims to determine the functional status and health-related quality of life outcomes o

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The CLEAR Trial is a 2x2 factorial randomized trial led by Professor Stuart Elborn and Professor Judy Bradley to assess the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves various study sites and potential new sit

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Understanding the role and benefits of partnering with a Clinical Trial Unit (CTU) is essential for potential Chief Investigators. A CTU handles various aspects of trial coordination, from developing trial materials to overseeing regulatory permissions and data management. UK Clinical Trials Units (

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The trial of O.J. Simpson for the brutal murders of Nicole Brown Simpson and Ron Goldman captivated the nation, with overwhelming evidence implicating Simpson. Despite the compelling case against him, Simpson's defense team, led by Johnnie Cochran, raised doubts about the integrity of the evidence a

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Simulation of a criminal jury trial where students act as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves the attempted murder of Kerry Bell-Leon, with witness selection varying in each round. Judges play crucial roles in presiding over the trial, scor

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Explore the capabilities of PENELOPE simulation software for analyzing samples with intricate structures like particles, inclusions, multilayers, lamellae, and phase boundaries. The software facilitates detailed investigations of material composition and electron-photon transport in diverse geometri

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Simulation design for authentic learning and assessment is a crucial aspect of education, particularly in the healthcare field. At the Australian Catholic University (ACU), simulation plays a significant role in providing students with authentic experiences that bridge the gap between theory and pra

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Simulation studies in Stata involve using (pseudo) random numbers to generate data from a distribution for studying statistical methods. This process helps to evaluate different scenarios and understand the properties of statistical techniques. Key components like ADEMP (Aims, Data-generating mechan

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The document presents simulation results for an LC-optimized PHY proposal for TGbb based on G.9991 PHY. It includes details on the simulation setup, frame detection results, header modulation, coding simulation results, payload modulation, and coding simulation results. The setup involved various re

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This simulation showcases a lumped thermoelectric module with PID control. The model evaluates the performance of a thermoelectric element in a nonisothermal fluid flow around a heat sink. A stationary simulation assesses the module's capabilities, followed by a transient simulation with a PID contr

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The Defense Modeling and Simulation Coordination Office (DND/CAF MSCO) is responsible for managing contractors, policies, and strategic activities related to modeling and simulation within the Canadian Armed Forces. The office focuses on supporting various organizations and enhancing capabilities th

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Explore the aerodynamic simulation of the MARINTEK Braceless Semisubmersible through advanced techniques and tools. Discover the unique aerodynamic actuator, simulation models, and tools used in the research conducted by Gordon Stewart, a post-doctoral researcher at NTNU. Gain insights into the expe

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