Myocardial infarction (heart attack), including its types, causes, symptoms, and first aid techniques. Discover how to recognize the signs of a heart attack and provide immediate care at home or in a hospital setting.

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Alinity i STAT High Sensitivity Troponin-I is a proprietary assay used in diagnosing myocardial infarction (MI) by quantitatively measuring cardiac troponin I in human plasma. This chemiluminescent microparticle immunoassay (CMIA) aids in the detection of MI, a significant aspect in managing heart d

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The OCTIVUS Randomized Clinical Trial compared the clinical efficacy and safety of Optical Coherence Tomography (OCT)-guided and Intravascular Ultrasound (IVUS)-guided strategies in patients undergoing PCI for significant CAD. The study aimed to determine if OCT-guided PCI is noninferior to IVUS-gui

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Dr. David Austin leads the PROACT study aiming to prevent chemotherapy-related heart damage in breast cancer and lymphoma patients using the ACE inhibitor enalapril. The research focuses on the effectiveness of enalapril in mitigating anthracycline cardiotoxicity, crucial for reducing long-term impa

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This study explores the use of CSL-112 infusions in patients with acute myocardial infarction to enhance high-density lipoprotein (HDL) function. By focusing on improving HDL-C function through ApoA-1 infusions, the research aims to enhance outcomes associated with cardiovascular events. The efficac

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This study explores the use of extracorporeal life support (ECLS) in patients with acute myocardial infarction complicated by cardiogenic shock. The researchers investigate the impact of ECLS on mortality and various secondary endpoints such as renal failure, recurrent infarction, and need for revas

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Cardiac output, stroke volume, end-diastolic and end-systolic volumes play vital roles in cardiovascular function. Factors affecting cardiac output include physiological conditions and pathological states like hyperthyroidism and myocardial infarction. Venous return, controlled by mechanisms like Fr

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Dive into the intricate details of cardiac electrical activity in this lecture led by Physiology Team 436. Explore topics like the cardiac conductive system, action potentials, refractory periods, excitation-contraction coupling, and the effects of autonomic stimulation on heart electrophysiology. D

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In patients with acute myocardial infarction (AMI) and multivessel coronary artery disease, this study aims to compare fractional flow reserve (FFR)-guided PCI with angiography-guided PCI for non-infarct-related artery lesions. The hypothesis is that selective PCI guided by FFR is superior to routin

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This lecture covers the criteria for diagnosing myocardial infarction (MI), features of ideal MI markers, the significance of plasma marker changes, and properties of markers such as cardiac troponins, creatine kinase, and myoglobin. It also discusses the new markers used for diagnosing MI and provi

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Congestive heart failure (CHF) is a condition characterized by systemic and pulmonary congestion due to the heart's inability to pump sufficient blood for the body's metabolism. It is closely linked to age and involves pathophysiology related to preload, afterload, contractility, and heart rate. Man

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Chest pain is a common presentation requiring swift identification and management to distinguish life-threatening causes like Myocardial Infarction. This article focuses on the approach to chest pain at a primary healthcare level, detailing cardiac and non-cardiac causes, recognizing urgent cases, a

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This rotation aims to enhance clinical skills in ECG interpretation with a focus on myocardial and conduction abnormalities, arrhythmias, and tachycardias. Students will engage in e-learning modules, case studies, and literature reviews to master ECG analysis. The course emphasizes patient care, med

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Digoxin, a cardiac glycoside, is utilized in managing congestive heart failure and atrial fibrillation due to its inotropic and chronotropic effects on the heart. It functions by inhibiting Na,K-ATPase, leading to increased intracellular calcium concentrations and augmented myocardial contractility.

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Cardiac failure is a condition where the heart is unable to meet tissue metabolic needs despite normal or increased venous return. Causes include decreased contractility, coronary blood flow, damaged valves, and more. Normal resting cardiac output is 5 Lt/mts, with adaptive mechanisms like the Frank

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Chronic coronary syndrome involves a dynamic process of atherosclerotic plaque accumulation and functional alterations in coronary circulation. It includes various clinical scenarios such as stable angina, asymptomatic ischemia, prior myocardial infarction, and more. The condition can be modified by

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Recognize the variables contributing to balanced myocardial supply and demand, identify etiopathogenic cascades in ischemic heart disease, and learn about drugs for acute angina relief and prophylaxis. Delve into the pharmacology of nitrates, vasodilators, and other antianginal therapies. Explore th

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Acute Coronary Syndrome (ACS) encompasses a spectrum of conditions involving reduced blood flow in the heart. Ischemic Heart Disease (IHD) is a leading cause of mortality worldwide, with ST-elevation myocardial infarction (STEMI) being more common in younger men. Prompt diagnosis, treatment, and adh

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Understanding medication persistence post myocardial infarction (MI) is crucial for optimizing patient outcomes. The ARTEMIS trial explored variation in P2Y12 inhibitor persistence rates using multiple measurement methods. This study design involved over 11,000 MI patients across 301 US hospitals, w

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The data report examines the prevalence of cardiovascular diseases in adult End-Stage Renal Disease (ESRD) patients in 2016 by treatment modality and age. It includes information on various cardiovascular conditions such as atrial fibrillation, acute myocardial infarction, coronary artery disease, a

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Explore the latest findings in cardiac research focusing on two critical clinical problems: Metabolic Syndrome (MetS) and Acute Myocardial Infarction. The studies involve human clinical data, blood sampling, adipose tissue biopsies, cell culture studies, thrombus aspiration, gene arrays, and regulat

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Acute coronary syndromes (ACS) encompass a spectrum of conditions such as unstable angina, non-ST-segment elevated MI (NSTEMI), and ST-segment elevated MI (STEMI) that result from coronary artery occlusion. Risk factors for ACS include family history of heart disease, obesity, smoking, and hypertens

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This study investigates the prognostic value of measuring post-PCI Fractional Flow Reserve (FFR) and intravascular imaging in patients with complex 3-vessel coronary artery disease (CAD), focusing on the impact on outcomes such as target vessel failure (TVF), including cardiac death, target vessel m

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Dr. Suneesh K., a Senior Resident in the Dept. of Cardiology at Calicut Medical College, delves into the crucial role of ECG analysis in identifying the culprit artery during ST-elevation myocardial infarction (STEMI). This presentation covers coronary circulation, blood supply of the heart, prevale

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In heart failure management, drugs play a crucial role in reducing preload and afterload, increasing cardiac contractility, and improving overall outcomes. Common drug classes include diuretics, aldosterone antagonists, ACE inhibitors, ARBs, beta-blockers, and vasodilators. These medications help al

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Acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow to a part of the heart is blocked, leading to heart muscle injury. Resolution of ST segment elevation on electrocardiogram after thrombolytic therapy can predict final infarct size, left ventricular function,

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The Anglo-Scandinavian Cardiac Outcomes Trial Lipid-Lowering Arm (ASCOT-LLA) conducted on hypertensive patients investigated the impact of atorvastatin versus placebo on cardiac outcomes. The study revealed a significant reduction in nonfatal myocardial infarction and fatal coronary heart disease wi

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Epithelial tissues play crucial roles in the human body, covering surfaces, lining cavities, and forming glands. They are highly cellular and rest on a basement membrane, separating them from connective tissues. Epithelial tissues serve functions such as protection, absorption, secretion, and contra

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Study by Nicholas Marston, MD, and team shows that high-sensitivity cardiac troponin at any detectable concentration is linked to a higher risk of major cardiovascular events in patients with stable ischemic heart disease. The research, conducted through the PEGASUS-TIMI 54 trial, aimed to further u

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Collaborative meta-analysis explores the efficacy of long-term dual antiplatelet therapy in preventing cardiovascular events in patients with previous myocardial infarction. Trials show heterogeneous results on the benefits and safety of prolonged therapy, with varying recommendations based on patie

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Explore a collection of clinical cases and image findings covering topics such as widened mediastinum, tracheal deviation, subdural hematoma, myocardial infarction, and arrhythmias. Learn about different diagnostic modalities, operative treatments, and potential complications associated with these c

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Postural drainage therapy is an intervention used for airway clearance by mobilizing secretions in specific lung segments towards the central airways. It involves placing the patient in various positions to facilitate gravity-assisted drainage. The therapy includes manual techniques such as percussi

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Jiao, a 74-year-old Chinese woman, was admitted to the hospital with chest pain and diagnosed with a mild myocardial infarction. She needed surgery due to severe plaque buildup in her coronary arteries. High cholesterol levels led to a restricted diet plan. Language barrier challenges arose when the

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Arkansas Department of Health (ADH) is focusing on improving acute myocardial infarction (AMI) care in Arkansas due to high mortality rates. They aim to develop effective strategies, implement timely interventions, and enhance data elements for better patient outcomes. Recognizing the urgent need, A

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This comprehensive guide delves into the various aspects of shock, including hypovolemia, pulmonary embolism, and acute myocardial infarction. It covers the general concept of shock, circulatory failure, phases of shock, pathophysiology, manifestations, diagnostic approaches, and complications such

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Anticoagulants play a crucial role in preventing blood clotting and are used in various medical conditions such as myocardial infarction and deep venous thrombosis. They include heparin, warfarin, and antiplatelet agents like aspirin. This article explores the mechanisms of action, indications, and

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Congestive heart failure (CHF) is a condition where the heart cannot pump enough blood to meet the body's needs, often caused by conditions like hypertension and coronary artery disease. Factors affecting cardiac output include preload, heart rate, stroke volume, afterload, and contractility. The pa

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Heart failure is a serious condition characterized by inadequate cardiac output. Compensatory responses include sympathetic nervous system activation, renin-angiotensin-aldosterone system stimulation, and natriuretic peptide release. Pharmacologic therapies target salt and water retention, afterload

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Chronic angina is a condition marked by impaired quality of life and decreased life expectancy, primarily due to myocardial ischemia. It is characterized by symptoms like tightness, heaviness, and pressure sensation, often located retrosternally. The pathophysiology involves a mismatch between oxyge

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The PARADISE-MI trial compared Sacubitril/Valsartan and Ramipril in patients with acute myocardial infarction. The primary outcome of cardiovascular death, heart failure hospitalization, or outpatient heart failure showed no significant difference between the two treatments. Detailed event rates and

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