Explore various physical and chemical methods used for gene transfer, including electroporation, particle bombardment, microinjection, ultrasound, and bacterial transformation. Learn how DNA enters the nucleus and the role of retroviruses in gene transfer efficiency. Understand the process of RNA co

0 views • 17 slides

This article provides insights into the status, regulatory considerations, and delivery methods of gene therapy and genome editing technologies. It discusses approved gene therapies in the US, human genome editing in clinical applications, and the regulatory authority of the FDA over gene therapy. T

2 views • 27 slides

Exploring the mechanisms of gene delivery via viral vectors, this content delves into the basics of viral structure, infection, and replication. It discusses common viral vector systems like Adenoviral and Lentiviral vectors, highlighting safety considerations and the production processes involved.

1 views • 19 slides

Explore the fascinating world of CRISPR/Cas9 gene editing technology through sessions led by experts like Roy Campbell and Howard Robinson. Delve into the working of gene editing, the CRISPR system, and the role of Cas9 enzyme. Learn about CRISPR's origin in prokaryotic organisms and its potential f

0 views • 33 slides

Gene expression is a crucial process that leads to the production of functional gene products like RNA and proteins. This article explores the regulation of gene expression in both prokaryotes and eukaryotes, covering the importance of regulating gene expression, types of regulation elements, specif

5 views • 22 slides

Regular expressions provide a powerful way to search for and manipulate text strings by specifying patterns. This content explores different aspects of regular expressions, including disjunctions, negations, more disjunctions, optional characters, anchors, and examples. By learning how to use regula

2 views • 46 slides

Bioinformatics involves analyzing biological sequences through sequence alignment to uncover functional, structural, and evolutionary insights. This process helps in tasks like annotation of sequences, modeling protein structures, and analyzing gene expression experiments. Basic steps include compar

0 views • 6 slides

Gene set enrichment tests help identify functional gene sets enriched in hit lists compared to background sets. Various biases (technical, biological, statistical) can lead to incorrect conclusions in data analysis, emphasizing the importance of recognizing and addressing them. Technical biases like

0 views • 29 slides

Delve into the world of genetics and genomics through the lens of integrative biology, investigating the differences between cell types, the rationale for gene expression profiling, and the analysis of differential gene expression in various diseases. Uncover the significance of gene ontology, co-ex

0 views • 22 slides

Exploring the forces behind evolutionary change, this content delves into natural selection, genetic drift, and gene flow. Examples such as the bottleneck effect, founder effect, and Amish population polydactylism are presented to illustrate how these mechanisms shape genetic diversity. The impact o

0 views • 14 slides

Exponents are a shortcut for repeated multiplication. Learn how to write expressions using exponents, evaluate expressions containing exponents, and apply rules for dealing with exponents. Explore examples and see how to write expressions in exponential form, evaluate them using calculators, and sim

0 views • 32 slides

Gene prediction in bioinformatics involves predicting gene locations in a genome using different approaches like statistical methods and similarity-based approaches. The similarity-based approach uses known genes as a template to predict unknown genes in newly sequenced DNA fragments. This method in

1 views • 40 slides

Epigenetics involves modifications that impact gene expression without altering DNA sequences, playing a crucial role in the transition from genotype to phenotype. This includes DNA methylation, histone modification, and microRNAs. DNA methylation, controlled by DNMT enzymes, can lead to either gene

5 views • 12 slides

The process of cloning and expressing the human insulin gene has revolutionized the production of insulin for treating diabetes. By using genetically engineered bacteria, the human insulin gene is inserted, expressed, and purified to create insulin for therapeutic use. This innovation has overcome c

0 views • 20 slides

Gene mutations play a significant role in molecular biology, leading to alterations in DNA sequences that can impact offspring. These mutations can arise spontaneously or be induced by various factors, such as mutagens. Understanding gene mutations is crucial for comprehending the genetic basis of c

2 views • 27 slides

Explore the difference between numeric and algebraic expressions, learn about the components of algebraic expressions - variables, coefficients, and constants. Discover how to identify variables, coefficients, and constants in expressions. Classify algebraic expressions as monomials, binomials, or t

0 views • 20 slides

Learn how to translate word phrases into algebraic expressions for addition, subtraction, multiplication, and division. Understand the key phrases associated with each operation to write expressions accurately. Enhance your skills in rewriting algebraic expressions with practical examples and concis

4 views • 17 slides

The Cre-Lox system, a powerful tool in genetic engineering, employs Cre recombinase to recombine specific DNA sequences (LoxP sites), allowing for precise genetic modifications such as deletions, inversions, and translocations. This system enables conditional gene expression, turning on or off trans

4 views • 9 slides

Gene drive technology is a cutting-edge approach aimed at combating malaria by spreading genetically modified genes in mosquito populations. This technology has the potential to protect endangered species and conserve nature. However, successful implementation requires complex collaborations, risk a

2 views • 16 slides

Epigenetics refers to changes in gene expression without altering the DNA sequence. This involves processes like DNA methylation, histone modification, and microRNAs. DNA methylation is controlled by DNA methyltransferase enzymes and plays crucial roles in gene activation and silencing. Histone modi

0 views • 13 slides

This presentation delves into the intricate concepts of gene duplication, DNA mutation, and read mapping in the context of molecular evolution. It explains the various types of mutations, the significance of gene duplication in generating new genetic material, and the process of read mapping to alig

0 views • 19 slides

Master the basics of algebraic expressions, simplification, and exponent rules in this lesson. Learn to interpret word problems into algebraic expressions, apply properties of real numbers, and solve algebraic problems step by step. Practice evaluating expressions, simplifying equations, and underst

0 views • 13 slides

This content covers various numerical expressions involving exponents, including examples of valid and invalid mathematical representations, matching worded expressions with their numerical equivalents, and identifying the correct expressions based on provided criteria.

0 views • 30 slides

This comprehensive content delves into the intricate mechanisms of gene regulation and control of gene expression. It covers topics such as transcriptional regulation, bacterial genes classification, and the role of regulatory proteins. Explore how genes are regulated at transcription, translation,

0 views • 17 slides

Explore the dynamic world of gene expression with the Chunky and Chips Gene Expression Group at the University of Notre Dame. Dive into topics like transcription, translation, and cellular events influencing gene expression. Delve into real-world scenarios and gain insights into the cellular level b

0 views • 20 slides

Investigating the potential of gene doping using PGC1a via Ormosil to enhance fitness outcomes in mice compared to exercise. Ormosil, a non-viral vector, is utilized for gene delivery, offering advantages in safety. Mice are divided into groups to receive treatment, exercise on treadmills, or remain

3 views • 8 slides

Restricted quantifiers and literal analysis in natural language processing reveal the distinctions between empirical and analytical expressions. While empirical expressions refer to non-trivial intensions that require empirical investigation, analytical expressions denote constant intensions that ca

1 views • 19 slides

In this case study, a 2-year-old male presenting with developmental delay and seizures was evaluated for a CNV at the 12p13.1p12.3 region. The CNV was found to overlap with the GRIN2B gene, a known haploinsufficient gene associated with developmental disorders. Despite potential additional scoring c

0 views • 17 slides

This instructional material focuses on teaching gene dosage compensation in the context of addressing the inactivation of one copy of Chromosome 21 in trisomy 21. The activity is designed for courses in Molecular Gene Regulation and Genetics, aiming to enhance students' understanding through hands-o

0 views • 19 slides

Epistasis is a phenomenon where the phenotypic expression of one gene is influenced by interactions with another gene. This concept, first introduced in 1909, plays a crucial role in genetics, affecting various traits and evolutionary processes. The difference between dominance and epistasis lies in

0 views • 41 slides

Utilizing dataflow analysis techniques, the concept of available expressions is discussed in the context of compiler construction. The goal is to identify common subexpressions that span basic blocks by calculating their availability at the beginning of each block. The process involves determining w

0 views • 59 slides

Rust is an expression language where most things have values. Learn about Rust expressions, blocks, declarations, conditional expressions, multi-case expressions, and iteration expressions in system software development. Explore the execution semantics, syntax, and best practices for writing safe an

0 views • 8 slides

The Gene Wiki Jamboree FaceBase Spring Meeting in 2010 aimed to create collaboratively-written and community-reviewed review articles for every gene in the human genome and every concept relevant to FaceBase. It highlighted the value of such articles, providing quick summaries and compilations of re

0 views • 13 slides

This lesson focuses on writing and reading algebraic and written expressions with grouping symbols and less than. Students will learn how to translate expressions containing groupings and less than. The lesson is designed to build on the previous day's lesson and challenge students' thinking. It set

0 views • 25 slides

The content focuses on evaluating expressions with variables, analyzing patterns, and maintaining mathematical skills. It includes practice exercises such as inserting parentheses to alter expression values and identifying errors in calculations. Additionally, it presents scenarios where individuals

0 views • 53 slides

This supplementary data includes raw data from agarose gel electrophoresis showing gene expression levels for human SOX17, FOXA2, AFP, ALB, and ACTB in various cellular samples. The gel images depict the expected sizes of amplicons for each gene in different conditions and time points of cell cultur

0 views • 5 slides

In this project, the focus is on identifying splice sites relevant to the inhibitory dopamine receptor gene (D2). The problem involves finding splicing elements within a specific range of known splice sites in the gene. The data provided includes the D2 gene entry in FASTA format, a database of spli

0 views • 13 slides

Reverse genetic approaches involve mutating a target gene to observe its phenotypic effects, providing insights into the gene's normal function. Techniques like gene knockout, knockdown, and homologous recombination are used to manipulate genes and study genetic pathways, leading to discoveries in v

0 views • 6 slides

The Extension Dogma challenges the assumption that linguistic expressions inherently possess meanings. Instead, it posits that expressions have extensions without necessary meanings that determine them. Theories of meaning should focus on the extensions of expressions, while psychological studies of

0 views • 30 slides

The lecture covers the essential aspects of hypothesis testing in gene expression profiling, emphasizing experimental design, confounding factors, normalization of samples, linear modeling, gene-level contrasts, t-tests, ANOVA, and significance assessment techniques. Practical insights are shared on

0 views • 9 slides