The OCTIVUS Randomized Clinical Trial compared the clinical efficacy and safety of Optical Coherence Tomography (OCT)-guided and Intravascular Ultrasound (IVUS)-guided strategies in patients undergoing PCI for significant CAD. The study aimed to determine if OCT-guided PCI is noninferior to IVUS-gui

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The Inter-Agency Standing Committee (IASC) plays a crucial role in coordinating humanitarian efforts, with a focus on mine action in the global protection cluster. This involves clear responsibilities, strategic planning, and advocacy to address humanitarian needs. The IASC Reference Module for Clus

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The PUSH-AHF trial, conducted at the University Medical Center Groningen, aimed to evaluate the effectiveness and safety of natriuresis-guided diuretic therapy in acute heart failure. The study design was pragmatic, prospective, single-center, open-label, randomized, and controlled. Key outcomes inc

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This study details the principal results of the RELIEVE-HF trial, investigating the safety and effectiveness of the V-Wave Ventura interatrial shunt device in patients with heart failure with reduced and preserved ejection fraction. Key inclusion and exclusion criteria are outlined, emphasizing the

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The Wood Innovation Cluster, established in 2018 in Skellefte municipality, brings together key stakeholders in the wood industry to foster regional growth and development. It coordinates research, development, education, and testing activities while promoting sustainable procurement. Through collab

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Empagliflozin's impact on cardiovascular and renal events in heart failure with reduced ejection fraction was assessed in the EMPEROR-Reduced trial led by Milton Packer, MD, and Faiez Zannad, MD. The trial, enriched for patients with severe left ventricular dysfunction, randomized participants to em

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In patients with acute myocardial infarction (AMI) and multivessel coronary artery disease, this study aims to compare fractional flow reserve (FFR)-guided PCI with angiography-guided PCI for non-infarct-related artery lesions. The hypothesis is that selective PCI guided by FFR is superior to routin

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Inter-Cluster Coordination and Information Management play vital roles in humanitarian emergencies. The coordination mechanism involves regular meetings convened by the RC/HC and coordinated by OCHA, providing opportunities for clusters to collaborate on shared planning, needs assessments, and poole

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Exploring Level 3 emergencies, the process of cluster activation and deactivation, and the core functions of the Nutrition Cluster at the country level. Learn about the criteria for cluster activation, gaps in response, and the strategic approach to humanitarian system-wide emergency activation. Dis

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Explore the various types of hearings available in the Court Management System, such as Motion Calendar, Special Sets, Calendar Call/Trial, Pre-Trial Conference, and Case Management. Learn how to set up new hearings/events and understand the process of generating trial orders and pre-trial conferenc

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Explore the transformative agenda and guidance for cluster coordination, emphasizing the roles of UNICEF as a cluster lead agency, core cluster functions, inter-cluster coordination, and management strategies for effective humanitarian response. Key focus areas include accountability, human financin

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The CLEAR Trial is a 2x2 factorial randomized trial evaluating the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the trial focuses on clinical and c

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Cluster beans, scientifically known as Cyamopsis tetragonoloba L., are valuable leguminous crops with economic importance due to their drought tolerance and industrial applications, particularly in gum production. They are cultivated for feed, fodder, and vegetable purposes, with their seeds rich in

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ACST-2 is a randomized trial comparing carotid artery stenting (CAS) versus carotid artery surgery (CEA) in asymptomatic patients with severe carotid stenosis. The trial, published in The Lancet in August 2021, involved 3625 patients. While surgery has been shown to reduce stroke rates, modern medic

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Welcome to the Sub-national Nutrition Cluster Coordination Training Workshop aimed at sharing key concepts, tools, and approaches for effective coordination of nutrition in emergencies. This training prepares participants for working in Nutrition Cluster/Sector Coordination, promoting dialogue and s

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Learn about the structures and roles within Nutrition Clusters at different levels, including the responsibilities of key actors such as the Cluster Coordinator, Information Manager, Strategic Advisory Group, and Technical Working Groups. Explore the involvement of governmental and non-governmental

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The ATLANTIS study evaluated the efficacy of low-dose amitriptyline (10-30 mg) in improving Irritable Bowel Syndrome (IBS) symptoms compared to placebo in a 6-month randomized controlled trial in a primary care setting. This important research aims to address the lack of definitive treatment guideli

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Preliminary results from the South Sudan Nutrition Cluster Performance Monitoring (CCPM) Review Workshop held in Juba, Republic of South Sudan on 24th January 2018. The workshop aimed to ensure efficient coordination, identify areas for improvement, raise awareness of support needed, and strengthen

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Explore the world of randomized algorithms through types like Las Vegas and Monte Carlo, with a focus on classic examples such as Quick Sort. Learn how randomness plays a crucial role in computation and discover the principles behind these algorithms. Dive into the applications of randomized algorit

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Randomized algorithms incorporate randomness into computations, with Las Vegas algorithms always providing the correct answer but varying in time, while Monte Carlo algorithms occasionally give wrong answers. Quick Sort is a classic Las Vegas algorithm that involves pivoting elements for sorting. Ch

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The CLEAR Trial is a 2x2 factorial randomized trial examining the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the study focuses on exacerbation ma

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Development of case report form worksheets for data collection in a randomized trial focusing on enteral glutamine use to minimize thermal injury. The document provides detailed instructions for research coordinators on data recording from medical charts to be entered into the electronic data captur

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A randomized controlled trial led by Dr. Mark J. Eisenberg at McGill University evaluated the efficacy and safety of E-Cigarettes (ECs) for smoking cessation. The study aimed to compare the effectiveness of nicotine and non-nicotine ECs with individual counseling against counseling alone. The trial

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Understanding the key components of a clinical trial research protocol is essential for conducting successful studies. This includes identifying session objectives, discussing trial protocol contents, exploring observational study elements, and learning about reporting guidelines. Study objectives f

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Enhance your trial skills in family law with a focus on evidence collection, trial strategies, and client examination. Learn best practices for preserving evidence, drafting persuasive statements, and navigating trials confidently. This workshop covers important aspects of evidence collection, such

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Explore the innovative tool nQuery Predict for accurate clinical trial milestone predictions, demonstrated in a webinar hosted by industry experts. Learn about key milestones, adaptive design considerations, enrollment predictions, and the significance of statistical approaches in optimizing trial d

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In this competition, students simulate a criminal jury trial where they take on roles as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves State v. Sinclair, focusing on the murder trial of Skyler Sinclair, a suspect in the death of an undercover officer

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Discover the minimum commitments for engaging in the Nutrition Cluster, learn about partnership principles, and understand how these guide collaborative efforts within the cluster. Explore partner commitments, principles of partnership, and engage in an exercise to apply these concepts practically.

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AIRWAYS-3 is a multi-centre, open-label, randomized trial evaluating the clinical and cost effectiveness of a supraglottic airway (SGA) versus tracheal intubation during in-hospital cardiac arrest (IHCA). The trial aims to determine the functional status and health-related quality of life outcomes o

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This slide deck explores the Social Change & Campaigning Learning Cluster conducted by the Sheila McKechnie Foundation. It delves into the aims of the cluster, participants, new skills acquired, and next steps. The learning clusters were designed to go beyond one-day events, providing residents with

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The CLEAR Trial is a 2x2 factorial randomized trial led by Professor Stuart Elborn and Professor Judy Bradley to assess the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves various study sites and potential new sit

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The 13th annual conference on Statistical Issues in Clinical Trials covered topics such as penalties for extra variation and limited degrees of freedom, the Diet-Heart Hypothesis, controlled trials, unit of randomization, and causal inference. Speakers highlighted the importance of addressing cluste

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Simulation of a criminal jury trial where students act as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves the attempted murder of Kerry Bell-Leon, with witness selection varying in each round. Judges play crucial roles in presiding over the trial, scor

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The Nutrition Cluster aims to support service delivery, inform strategic decision-making, and plan and implement cluster strategies to address the needs and priorities of affected populations. Core functions include supporting service delivery, advocacy, capacity-building, and monitoring and evaluat

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The CLEAR Trial is a 2x2 factorial randomized trial assessing the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley, the trial involves randomization, sealed

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The CLEAR Trial is a 2x2 factorial randomized trial evaluating the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients. The trial, led by Professor Stuart Elborn and Professor Judy Bradley, focuses on pharmacovigilance activities, adverse event defini

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Abusive head trauma (AHT) is a significant cause of trauma-related death and disability in young children. The journey to address missed cases of AHT began with the index case in 1995, leading to a cluster randomized trial aiming to improve recognition and prevention. The consequences of missed AHT

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This content covers a lecture on a randomized algorithm for finding an approximate median element using elementary probability theory. It discusses the importance of insight and basic probability in designing and analyzing such algorithms. The lecture presents a simple probability exercise involving

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This study explores the outcomes of a site-randomized trial utilizing a combined cognitive behavioral therapy and medication management algorithm for treating depression among youth with HIV in the U.S. The team involved includes medical officers, data managers, statisticians, clinical trial special

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IHEP is extending its HTC cluster to accommodate the data processing needs of over 15 experiments in the field of high energy physics. The motivation behind this expansion includes the need for more resources, existing data processing limitations, and user preferences for local analysis. The cluster

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