Understanding Safety Signal Detection in Vaccine Surveillance
The European Medical Association and the CDC utilize Proportional Reporting Ratio (PRR) to identify serious drug reactions in their vaccine surveillance systems. Different statistical methods are employed to generate Signal Detection Reports (SDRs), with PRR being a central tool. The PRR helps in identifying disproportionate reporting of adverse events, triggering further clinical review when necessary. Despite the use of PRR analysis, transparency in releasing results by authorities like the CDC has raised questions. Conducting personal PRR analysis reveals insights that should ideally have been communicated by official sources.
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Presentation Transcript
SAFETY SIGNAL LOOKUP FOR VACCINES
HOW DO WE DETECT SAFETY SIGNALS The European Medical Association uses Proportional Reporting Ratio to detect serious drug reactions in their Eudravigilance Data Analysis System
QUOTE Different statistical methods to generate SDRs are in use. In the EudraVigilance Data Analysis System, the Proportional Reporting Ratio (PRR) has been implemented in the first release. Other methods will be considered for future implementation. European Medicines Agency,(2006), "Guideline on the Use of Statistical Signal Detection Methods in the Eudravigilance Data Analysis System"
HOW DO WE DETECT SAFETY SIGNALS The CDC uses Proportional Reporting Ratio to detect serious drug reactions in their VAERS System
CENTERS FOR DISEASE CONTROL AND PREVENTION, (2021) "VACCINE ADVERSE EVENT REPORTING SYSTEM (VAERS) STANDARD OPERATING PROCEDURES FOR COVID-19 (AS OF 29 JANUARY 2021) "CDC will perform Proportional Reporting Ratio (PRR) analysis [...], excluding laboratory results, to identify AEs that are disproportionately reported relative to other AEs. [...] To determine if results need further clinical review, consider if clinically important, unexpected findings, seriousness, specific syndrome or diagnosis rather than non-specific symptoms"
SO WHAT IS PROPORTIONAL REPORTING RATIO It detects when the proportion of reports with a symptom is higher than expected. 10000 reports for drug A Symptom S occurs 200 times 10000 reports for drug B Symptom S occurs 50 times The Proportional Reporting Ratio = 20/5 = 4 The CDC criteria for a safety signal is when PRR > 2
SO DID THE CDC DETECT ANYTHING ? They claim to have carried out PRR analysis BUT They are not revealing the results DESPITE Several freedom of information requests by Senators
SO I did the PRR analysis myself I am going to tell you what they should have told you.
THE METHOD I used all the VAERS data from 1990 to 2023. I counted the frequency of each symptom for each vaccine I calculated the PRR of each symptom for each vaccine If the PRR for any symptom was > 2, then it was a safety signal. Simple.
RESULTS Lets look at the symptom of Thrombosis Is the PRR > 2
SAME SYMPTOM CONSISTENCY (SSC) This is where the same symptom occurs in different organs. This shows that the drug is having a consistent effect through out the body.
OH, HERES SOME MORE This is what you call really, really consistent, across multiple organs. I should add that the higher the PRR the stronger the signal.
There are 94 symptoms in VAERS that contain the word THROMBOSIS. COVID 19 has a high PRR (> 2) for 89 of them. No other vaccine (there are 100 different vaccines in VAERS) has a high PRR for more than 4 of them. Its like comparing a medicine with a weapon. DO OTHER VACCINES SHOW SIMILAR PRRS FOR THROMBOSIS No The medicine has a harmful side effect The weapon has a harmful main effect
RELATED SYMPTOM CONSISTENCY (RSC) This is where closely related conditions also show a high PRR. In the case of THROMBOSIS, related conditions would be D-dimer , Fibrin Infarctions Occlusions Embolisms Clots Aneurysms Coagulation DO these related conditions all show a consistent high PRR
RELATED SYMPTOM CONSISTENCY (RSC) This is where closely related conditions also show a high PRR. In the case of THROMBOSIS, related conditions would be D-dimer , Fibrin Infarctions Occlusions Embolisms Clots Aneurysms Coagulation DO these related conditions all show a consistent high PRR
RELATED SYMPTOM CONSISTENCY (RSC) This is where closely related conditions also show a high PRR. In the case of THROMBOSIS, related conditions would be D-dimer , Fibrin Infarctions Occlusions Embolisms Clots Aneurysms Coagulation DO these related conditions all show a consistent high PRR
RELATED SYMPTOM CONSISTENCY (RSC) This is where closely related conditions also show a high PRR. In the case of THROMBOSIS, related conditions would be D-dimer , Fibrin Infarctions Occlusions Embolisms Clots Aneurysms Coagulation DO these related conditions all show a consistent high PRR
RELATED SYMPTOM CONSISTENCY (RSC) This is where closely related conditions also show a high PRR. In the case of THROMBOSIS, related conditions would be D-dimer , Fibrin Infarctions Occlusions Embolisms Clots Aneurysms Coagulation DO these related conditions all show a consistent high PRR
DOWNLOAD SPREADSHEETS You can find them on the web site Howbad.info SAFETY RATINGS GROUPED BY VACCINE SAFETY RATINGS GROUPED BY SYMPTOM
SAFETY SIGNAL Enter a vaccine name and view all its symptoms ranked by PRR Enter a symptom and view all the vaccines ranked by PRR for that symptom You can find it on the website Howbad.info. You can add it to your website It provides an analysis for 98 different vaccines and for 16575 symptoms Based on 32 years of data.
PRACTICAL EXAMPLES Question Is cancer an effect of the COVID jab ? For these cancers, COVID19 Bivalent has higher scores Question Has cancer accelerated with Bivalent?
PRACTICAL EXAMPLES Question Is cancer an effect of the COVID jab ? For these cancers, COVID19 jab has higher scores than COVID Bivalent Question Is this because the cancers associated with bivalent take longer to develop?
TYPES OF CANCER Carcinoma Sarcoma Melanoma Leukemia Lymphoma Myeloma Bivalent elevates carcinoma in breasts, kidneys, pancreas, lung and skin
TYPES OF CANCER Carcinoma Sarcoma Melanoma Leukemia Lymphoma Myeloma Lymphoma is where mutations are occurring in the immune cells themselves COVID monovalent causes T cell lymphoma COVID bivalent causes B cell lymphoma.
FOETAL INJURY Question Has foetal injury accelerated with the bivalent?
DTAP Is DTAP like thalidomide
Thalidomide has strong connections with Nazi, Eugenics SPOOKY CONNECTION QUESTION : What about DTAP s connections
AMYLOID CLOTS This is what undertakers have observed Build up of amyloid in the brain, heart and blood
BIOMARKERS FOR AMYLOID CLOTS Bio markers for amyloidosis are also elevated, confirming the high PRRs for amyloidosis
SAFETY SIGNAL Analysis for 98 different vaccines 16575 symptoms Based on 32 years of data. Enter a vaccine name and view all its symptoms ranked by PRR Enter a symptom and view all the vaccines ranked by PRR for that symptom Critical information for checking out childhood vaccines. Add it to your website
