Water-borne Diseases and Pathogens

 
Water
 
borne
 
diseases
 
Prepared 
by
G.K.ARACHI
 
Introduction
 
 
Drinking 
water 
is a major
source
 
of
 
microbial
 
pathogens
in
 developing
 
countries.
 
 
Waterborne 
disease cause
more 
than 2 million 
deaths
and 4 billion 
cases of diarrhea
annually.
 
 
9 
out of 
10 
deaths 
are 
in
children and virtually all 
of
the
 
deaths
 
are 
in
 developing
countries.
 
The
 
importance
 
of
 
water
 
quality
 
Safe
 
water
 
is
 
a
 
precondition
 
for
 
health
 
and
development
 
and
 
a
 
basic
 
human
 
right.
 
Water-related
 
diseases
 
caused
 
by
 
insufficient
 
safe
water
 
supplies
 
coupled
 
with
 
poor
 
sanitation
 
and
hygiene.
 
Terms
 
to
 
be
 
known
 
Potable(clean)
 
water:
it is 
free 
of 
all 
objectional material, 
including 
pathogens, 
tastes,
odors, 
colours, toxins, 
radioactive 
material, 
organisms, 
oils,
gases, etc.
 
contaminated
 
or
 
polluted
 water
Water 
contaminated 
with 
sewage, domestic 
or industrial
waste
 
with
 
chemicals
 
and
 pathogenic
 microorganisms
 
.
undefined
 
Diseases
 
Related
 to
 
Water
 
Water-borne
 
Diseases
 
Diseases
 
caused
 
by
 
ingestion
 
of
 
water
 
contaminated
 
by
human
 
or animal
 
faeces
 
or
 
urine
 
,
 
which
 
contain
pathogenic
 
microorganisms
 
Many
 bacteria,
 
viruses,
 
protozoa
 and 
parasites
 
can
 
cause
disease
 when
 
ingested.
 
 
The
 
majority
 
of
 
these 
pathogens
 
derive
 
from
 
human
 
or
animal 
faeces, 
and 
are 
transmitted through 
the 
faecal-oral
route.
 
 
Although
 
both
 
animal
 
and
 
human
 
faeces
 
are
 
threats
 
to
human 
health, 
human 
faeces 
are 
generally 
the 
most
dangerous.
 
 
Faecal 
pathogens can 
be 
classified as 
causing both 
water-
borne
 and
 
water-washed 
diseases.
 
Orally
 
transmitted
 
waterborne
pathogens
 
Bacteria
Campylobacter
 
jejuni/coli
E.
 
coli
 
 
enterohaemorrhagic
Legionella
 
spp.
Salmonella
 
typhi
Shigella
 
spp.
Vibrio
 
cholerae
Yersinia
 
enterocolitica
Pseudomonas
 
aeruginosa
 
Viruses
Adenoviruses
Enteroviruses(polio)
Hepatitis 
A
Hepatitis
 
E
Noroviruses
 
and
 
Sapoviruses
Rotavirus
 
Protozoa
Cryptosporidium
 
parvum
Entamoeba
 
histolytica
Giardia 
lamblia/intestinalis
Naegleria
 
fowleri
Toxoplasma
 
gondii
 
Helminths
Dracunculus
 
medinensis.
Schistosoma
 
spp.
 
Diseases
 
that
 
transmitted
 
by
 
water
 
can
 
be
divided
 
in
 
to:
1.
Diarrhoeal
 
water-borne
 
diseases
2.
Non-diarrhoeal
 
water-borne
 
diseases
 
Diarrhoeal
 
water-borne
 
diseases
 
Most
 
water-borne
 
pathogens
 
infect 
the 
gastrointestinal
 
tract
and
 
cause
 
diarrhoeal
 
disease.
The
 
most common
 
causes
 
of 
severe
 
diarrhoeal
 
disease 
are:
-Rotaviruses.
-Pathogenic
 
E.
 
coli
-Campylobacter
 
jejuni.
-Entamoeba
 
hystolica
-Giardia
 
intestinalis
 
(also
 
known
 as
 
G.
 
lamblia)
-Cryptosporidium
 
parvum
-Norwalk-like
 
viruses
 
Epidemic
 
diarrhoeal
 
disease
Two
 
diarrhoeal pathogens:
Shigella
 
dysenteriae
Vibrio
 
cholera
 
-
are
 particularly
 
infectious
 
and
 can
 
cause
 
severe
 
epidemics.
-Epidemic diarrhoea (both shigellosis 
and 
cholera) 
can 
be
triggered
 
by
 
natural
 
disasters
 
or
 
political
 
upheavals 
that
disrupt
 
the
 normal
 
water
 
supply.
 
Non-diarrhoeal
 
water-borne
 
diseases
 
While
 
most
 
water-borne
 
pathogens
 
cause
diarrhoeal
 
disease,
 
a
 
few
 
important
 
water-borne
diseases
 
affect
 
other
 
parts
 
of
 
the
 
body:
 
Typhoid
 
fever
is
 
caused
 
by
 
ingestion
 
of
 
Salmonella
 
typhi
 
bacteria
in 
food
 or 
water
 
and 
affects
 
about
 
17 
million
people each
 
year,
 
causing some
 
600,000
 
deaths.
 
Hepatitis(
or
 
liver
 
inflammation)
is 
caused
 
by
 
viral 
infection.
 
A
 
and E, 
are
 
primarily
caused
 
by
 
ingestion
 
of
 
faecally
 
contaminated
drinking
 
water.
 
Hepatitis
 
A
 
causes
 
about 1.5
 
million
infections
 
each
 
year
 
(mostly
 
in
 
children)
 
Polio
is a 
highly 
infectious viral 
disease that 
mainly
affects
 
children
 
under
 
5.
 poliovirus
 is
 
primarily
transmitted
 through
 
the 
faecal-oral
 
route,
safe
 
water
 
and
 
sanitation
 
interventions
 
can
help
 
reduce
 
risk.
 
Legionellosis
Legionella
 
can 
grow
 
in
 
water
 
storage
 tanks,
boilers,
 
or
 
pipes 
in
 distribution 
systems.
Outbreaks 
of
 
Legionnaire’s
 disease
 
are
 
fairly
rare.
 
Leptospirosis
is
 
a
 
bacterial
 
disease
 
caused
 
by
 
ingestion
 
or
 
bodily
 
contact
with 
water 
contaminated 
with the 
urine of 
infected 
animals,
especially
 rats.
 
The
 
disease
 
is
 
difficult
 
to
 diagnose
 
and
 
is 
often
overlooked,
 but
 
may
 
be
 
important,
 
especially
 
following
flooding.
 
Water-washed
 
Diseases
 
Diseases
 
caused
 
by
 
poor
 
personal
 
hygiene
 and
 
skin
and
 
eye
 
contact
 
with
 
contaminated
 
water
 
Four
 types
 
of 
water-washed
 
diseases
 
are
 
considered
 
here:
 
1.
 
Soil-transmitted
 
helminths
transmitted
 
primarily
 
through
 contact
 
with 
contaminated
soil.
 
The
 most
 
prevalent
 
helminths
 
are:
 
Ascaris
 
(
Ascarislumbricoides)
hookworm
 
(Ancylostoma
 
duodenale
 
and
Necator
 
americanus)
whipworm
 
(
Trichuris
 
trichiura).
 
-
helminths
 
cause
 
about 12,000
 
deaths
 
each
 
year
-improved
 
hygiene
 
and
 
sanitation
 
can
 
reduce
 
disease
incidence.
 
Ascaris lumbricoides
 
2.
 
Acute
 Respiratory
 
Infections
Acute 
respiratory 
infections 
(ARI) 
including 
pneumonia 
are
responsible 
for 
approximately 
19% 
of 
total 
child 
deaths every
year.
There 
is an 
increasing body of evidence 
demonstrating that
good
 
hygiene
 
practices,
 
especially
 hand-washing
 
with 
soap,
can
 significantly
 
reduce
 
the
 
transmission
 
of
 
ARI
 
3.
 
Skin
 
and
 eye
 
diseases
Trachoma
Trachoma
 
is 
caused 
by
 the
 
Chlamydia
 
trachomatis
 
bacteria,
which
 
inflame
 
the
 
eye.
The
 
best
 
control
 
method
 
for
 
trachoma
 
is
 
improved
 access
 
to
water
 
for
 
face 
washing.
 
Ringworm
 
(tinea)
is an 
infectious 
disease of 
the 
skin, 
scalp 
or nails. 
In 
spite 
of
the
 
name,the
 disease
 
is 
caused 
by
 
the
 
fungus(tinea
 
corporis).
 
Water-based
 
Diseases
 
Diseases
 
caused
 
by
 
parasites
 
found
 
in
 
intermediate
organisms
 
living
 
in
 
contaminated
 
water
 
Schistosomiasis
 
(bilharziasis)
Infection 
is 
caused 
by flatworms 
called 
schistosomes, 
which
spend
 
part
 
of
 their 
life
 
cycle
 
inside
 
snail
 
hosts. People
 
become
infected through 
skin 
contact 
with 
infected 
water, 
mainly
during 
fishing
 and agricultural
 
activities.
 
Dracunculiasis
 
(guinea-worm
 
disease)
caused 
by 
the 
roundworm 
Dracunculus 
medinensis
. 
Guinea-
worm 
larvae 
in 
water bodies 
are 
ingested 
by 
the 
Cyclops
water flea. 
People 
become
 
infected
 by 
drinking
 water
contaminated 
with 
Cyclops: 
the 
larvae 
are released in the
stomach, 
migrate 
through the 
intestinal 
wall, 
and 
grow to
adult 
worms.
 
Water-related
 
Diseases
 
Water-related
 
diseases 
are
 caused 
by
 
insect
 vectors,
especially
 
mosquitoes,
 that breed 
or 
feed 
near
contaminated
 
water.
 
These
 
diseases
 
are
 
not
 
directly
 
related
 
to
 
drinking-water
quality.
 
However,
 
consideration
 
of
 
vector
 
control
 
can
reduce
 
the
 
potential
 
for
 
water
 
related
 
disease
 
transmission.
 
The
 
most
 
common
 
vector
 
insects
 
are
 
mosquitoes
 
and
 
flies.
 
Mosquito-borne
 
diseases:
-
malaria
 
(plasmodium-parasite)
-
yellow
 
fever
 
(virus)
-
dengue
 
fever
 
(virus)
-
Filariasis 
(worm)
filariasis
 
Fly-borne
 
diseases
 
-
onchocerciasis
 
(river-blindness)
caused
 
by
 
filarial
 
worm
 
Onchocerca
 
volvulus
 
-
trypanosomiasis 
(West 
African sleeping
sickness)caused
 
by
 a 
parasite
-
called
 
Trypanosoma
 
bruce
 
-
leishmaniasis
 
(Kala-azar)
Kala-azar
-
Loiasis
 
-
 
caused 
by
 
parasitic
 
worm 
Loa
 
loa
 
 
Loiasis
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Drinking contaminated water can lead to water-borne diseases, causing millions of deaths annually, especially in developing countries. Potable water is essential for health and development, as water-related diseases arise from inadequate water quality and poor sanitation practices. Various pathogens transmitted through oral-fecal route pose health risks, including bacteria like E. coli and Vibrio cholerae, as well as viruses like Hepatitis A and Rotavirus.

  • Water-borne diseases
  • Pathogens
  • Contaminated water
  • Sanitation
  • Health risks

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  1. Water borne diseases Prepared by G.K.ARACHI

  2. Introduction Drinking water is a major sourceof microbialpathogens in developingcountries. Waterborne disease cause more than 2 million deaths and 4 billion cases of diarrhea annually. 9 out of 10 deaths are in children and virtually all of the deathsare in developing countries.

  3. The importance of water quality Safe water is a precondition for health and development and a basic human right. Water-related diseases caused by insufficient safe water supplies coupled with poor sanitation and hygiene.

  4. Termsto be known Potable(clean)water: it is free of all objectional material, including pathogens, tastes, odors, colours, toxins, radioactive material, organisms, oils, gases, etc. contaminated or polluted water Water contaminated with sewage, domestic or industrial waste with chemicals and pathogenic microorganisms .

  5. Diseases Related to Water

  6. Water-borneDiseases Diseases caused by ingestion of water contaminated by human or animal faeces or urine , which contain pathogenic microorganisms

  7. Many bacteria, viruses, protozoa and parasites can cause disease when ingested. The majority of these pathogens derive from human or animal faeces, and are transmitted through the faecal-oral route. Although both animal and humanfaeces are threats to human health, human faeces are generally the most dangerous. Faecal pathogens can be classified as causing both water- borne and water-washed diseases.

  8. Orally transmitted waterborne pathogens Bacteria Campylobacterjejuni/coli E. coli enterohaemorrhagic Legionellaspp. Salmonellatyphi Shigella spp. Vibriocholerae Yersinia enterocolitica Pseudomonasaeruginosa

  9. Viruses Adenoviruses Enteroviruses(polio) Hepatitis A Hepatitis E Noroviruses and Sapoviruses Rotavirus

  10. Protozoa Cryptosporidium parvum Entamoeba histolytica Giardia lamblia/intestinalis Naegleria fowleri Toxoplasma gondii

  11. Helminths Dracunculus medinensis. Schistosoma spp.

  12. Diseases that transmitted by water can be divided in to: 1. Diarrhoeal water-bornediseases 2. Non-diarrhoealwater-borne diseases

  13. Diarrhoeal water-borne diseases Most water-borne pathogens infect the gastrointestinaltract and cause diarrhoeal disease. The most common causes of severe diarrhoeal disease are: -Rotaviruses. -Pathogenic E. coli -Campylobacterjejuni. -Entamoeba hystolica -Giardia intestinalis (also known as G. lamblia) -Cryptosporidium parvum -Norwalk-like viruses

  14. Epidemic diarrhoealdisease Twodiarrhoeal pathogens: Shigelladysenteriae Vibriocholera -are particularly infectious and can causesevereepidemics. -Epidemic diarrhoea (both shigellosis and cholera) can be triggered by natural disastersor political upheavals that disrupt the normal water supply.

  15. Non-diarrhoeal water-borne diseases While most water-borne pathogens cause diarrhoealdisease, a few important water-borne diseases affect other parts of the body: Typhoidfever is caused by ingestion of Salmonella typhi bacteria in food or water and affects about 17 million people each year, causing some 600,000 deaths. Hepatitis(or liver inflammation) is caused by viral infection. A and E, are primarily caused by ingestion of faecally contaminated drinking water. Hepatitis A causes about 1.5 million infections each year (mostly in children)

  16. Polio is a highly infectious viral disease that mainly affects children under 5. poliovirus is primarily transmittedthrough the faecal-oral route, safe water and sanitation interventions can help reduce risk. Legionellosis Legionella can grow in water storage tanks, boilers, or pipes in distribution systems. Outbreaks of Legionnaire sdisease are fairly rare.

  17. Leptospirosis is a bacterial disease caused by ingestion or bodily contact with water contaminated with the urine of infected animals, especially rats. The disease is difficult to diagnose and is often overlooked, but may be important, especially following flooding.

  18. Water-washedDiseases Diseases caused by poor personal hygiene and skin and eye contact with contaminated water

  19. Four types of water-washed diseases are considered here: 1. Soil-transmitted helminths transmitted primarily through contact with contaminated soil. The most prevalenthelminths are: Ascaris (Ascarislumbricoides) hookworm (Ancylostoma duodenale and Necator americanus) whipworm (Trichuristrichiura). -helminths cause about 12,000 deaths each year -improved hygiene and sanitation can reduce disease incidence. Ascaris lumbricoides

  20. 2. Acute RespiratoryInfections Acute respiratory infections (ARI) including pneumonia are responsible for approximately 19% of total child deaths every year. There is an increasing body of evidence demonstrating that good hygiene practices, especially hand-washing with soap, can significantly reduce the transmission of ARI

  21. 3. Skin and eye diseases Trachoma Trachoma is caused by the Chlamydia trachomatis bacteria, which inflame the eye. The best control methodfor trachoma is improved access to waterfor face washing.

  22. Ringworm(tinea) is an infectious disease of the skin, scalp or nails. In spite of the name,the disease is caused by the fungus(tinea corporis).

  23. Water-basedDiseases Diseases caused by parasites found in intermediate organisms living in contaminated water

  24. Schistosomiasis(bilharziasis) Infection is caused by flatworms called schistosomes, which spend part of their life cycle inside snail hosts. People become infected through skin contact with infected water, mainly during fishing and agriculturalactivities.

  25. Dracunculiasis(guinea-worm disease) caused by the roundworm Dracunculus medinensis. Guinea- worm larvae in water bodies are ingested by the Cyclops water flea. People become infected by drinking water contaminated with Cyclops: the larvae are released in the stomach, migrate through the intestinal wall, and grow to adult worms.

  26. Water-relatedDiseases Water-related diseases are caused by insect vectors, especially mosquitoes, that breed or feed near contaminatedwater.

  27. These diseases are not directly related to drinking-water quality. However, consideration of vector control can reduce the potential for water related disease transmission. The most common vector insects are mosquitoes and flies. Mosquito-bornediseases: -malaria (plasmodium-parasite) -yellow fever (virus) - dengue fever (virus) - Filariasis (worm) filariasis

  28. Fly-borne diseases - onchocerciasis(river-blindness) caused by filarialworm Onchocerca volvulus - trypanosomiasis (West African sleeping sickness)caused by a parasite - calledTrypanosoma bruce - leishmaniasis (Kala-azar) Kala-azar - Loiasis - caused by parasitic worm Loa loa Loiasis

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