HER2 activation plays a crucial role in promoting tumor proliferation and survival in NSCLC. Driven by oncogenic downstream signaling pathways, HER2 overexpression and gene amplification lead to the formation of heterodimers and activation of key signaling cascades. Additionally, HER2 mutations are

0 views • 36 slides

This presentation by Dr. Mark L. Prasarn focuses on the importance of assessing preoperative bone health in older patients undergoing spine fusion surgery. It covers the potential bone-related complications, osteogenesis process, osteoconduction, osteoinduction, and the favorable biomechanical envir

1 views • 67 slides

This slideshow provides an overview of tumor classification, nomenclature, and key concepts in pathology. It covers the definitions of neoplasm, tumor, and oncology, the classification of tumors into benign and malignant categories, as well as the importance of stroma in tumor behavior. It also expl

4 views • 61 slides

This material provides a structured approach to managing critically ill patients, focusing on the primary survey steps including airway and cervical spine control. It covers assessment techniques, interventions, and guidelines for ensuring patient safety, particularly in cases of potential airway co

1 views • 38 slides

Explore best spine surgery clinic in Medavakkam, Perumbakkam, Royapettah, Chennai, the best clinic for back pain and neck pain treatment. Expert care at the leading spine surgery center.

3 views • 2 slides

Medspine: Your Destination for Premier Spine Surgery Solutions in Chennai\n\nIn the bustling healthcare landscape of Chennai, finding the optimal care for spinal issues can be daunting. However, nestled within the city's medical hub lies Medspine, a beacon of excellence in spine surgery and treatmen

0 views • 2 slides

Medspine: Your Destination for Premier Spine Surgery Solutions in Chennai\n\nIn the bustling healthcare landscape of Chennai, finding the optimal care for spinal issues can be daunting. However, nestled within the city's medical hub lies Medspine, a beacon of excellence in spine surgery and treatmen

1 views • 2 slides

Explore best spine surgery clinic in Medavakkam, Perumbakkam, Royapettah, Chennai, the best clinic for back pain and neck pain treatment. Expert care at the leading spine surgery center.

1 views • 2 slides

Athletic programs should have an Emergency Action Plan (EAP) for pre-hospital spine-injury care. Key recommendations include transportation to a designated trauma center, conducting pre-event medical time outs, and involving trained personnel in equipment removal. Removal of helmet and shoulder pads

2 views • 5 slides

Discover the best spine tumor treatment at Medspine, the leading hospital with top surgeon and specialist in Medavakkam, Perumbakkam, Royapettah, Chennai.

3 views • 2 slides

Explore best spine surgery clinic in Medavakkam, Perumbakkam, Royapettah, Chennai, the best clinic for back pain and neck pain treatment. Expert care at the leading spine surgery center.

6 views • 3 slides

Back Pain that radiates to other parts of your Body\n\nBack pain more in the night time could be o sign of spine surgeon in jaipur\n\n\nBook an Appointment at 9650052767\nDr. Himanshu Gupta\nMicroscopic & Endoscopic Brain & Spine Neurosurgeon\nJeevan Rekha Super Speciality Hospital, Jaipur\n

0 views • 7 slides

Explore best spine surgery clinic in Medavakkam, Perumbakkam, Royapettah, Chennai, the best clinic for back pain and neck pain treatment. Expert care at the leading spine surgery center.

1 views • 3 slides

Explore best spine surgery clinic in Medavakkam, Perumbakkam, Royapettah, Chennai, the best clinic for back pain and neck pain treatment. Expert care at the leading spine surgery center.

1 views • 3 slides

Dr. Himanshu Gupta is known not only for his mastery of surgical techniques, particularly in microsurgery and Endosurgery for brain tumors but also for his exceptional skills in managing patients requiring trauma, brain, and spine surgeries.\n\nHis focus lies in exclusive neurosurgery, making him a

0 views • 7 slides

Discover the best spine tumor treatment at Medspine, the leading hospital with top surgeon and specialist in Medavakkam, Perumbakkam, Royapettah, Chennai.

8 views • 2 slides

Discover the best spine tumor treatment at Medspine, the leading hospital with top surgeon and specialist in Medavakkam, Perumbakkam, Royapettah, Chennai.

0 views • 2 slides

Best spine physiotherapy services in Medavakkam, Perumbakkam, Royapettah, Chennai. Our clinic offers the best care from expert physiotherapists. Book your appointment now!

1 views • 2 slides

Grading and staging are crucial in determining the aggressiveness and extent of malignant tumors. Grading involves assessing the level of malignancy based on cell differentiation and mitotic activity, while staging considers the size of the tumor, lymph node involvement, and presence of metastases.

7 views • 31 slides

This trial aims to compare the efficacy and safety of molecularly-guided therapy or cancer immunotherapy based on genomic profiling with platinum-based chemotherapy in patients with cancer of unknown primary site. The study design includes multiple treatment regimens guided by genomic profiles, with

4 views • 9 slides

WAGR syndrome is a rare genetic condition associated with Wilms Tumor, aniridia, and developmental delays. Wilms Tumor is a form of kidney cancer mostly affecting children and is linked to genetic disorders like WAGR syndrome. The risk of Wilms Tumor is higher in children with WAGR syndrome, with po

1 views • 14 slides

Degenerative spine disease is a prevalent condition affecting millions, leading to substantial healthcare costs. The anatomy and physiology of spine degeneration involve the three-joint complex theory. Pathologically, disc degeneration impacts the nucleus pulposus and annulus fibrosis, contributing

0 views • 37 slides

Positron Emission Tomography (PET) is a medical imaging technique focusing on metabolic differences in the body. By using positron-emitting radioisotopes, PET can detect how molecules are taken up by healthy and cancerous cells, aiding in accurate tumor localization with lower doses. The evolution o

0 views • 6 slides

Research collaboration aimed to enhance locoregional tumor control and reduce distant failure by combining charged particles irradiation and anticancer drug Epothilone B in cultured human tumor cells from Milano and Roma. The study explores the impact on clonogenic survival, growth curves, and deter

0 views • 13 slides

The Gamma Knife Stereotactic Radiosurgery is a precise and effective treatment method where highly focused radiation beams are used to target tumors and abnormalities in the brain. It does not remove the tumor directly but affects DNA, cell growth, and blood vessels. The procedure involves three mai

0 views • 51 slides

NCI-MATCH is a groundbreaking clinical trial aiming to match tumor gene alterations with targeted therapies. The interim analysis results revealed impressive patient enrollment and site participation exceeding expectations. Despite challenges with pausing new patient registrations for the analysis,

0 views • 26 slides

Delve into the early years of the Cervical Spine Research Society, established by pioneers like J. William Fielding, Edward Dunn, and other founding members in 1973. The society aims to foster the exchange of ideas and advancements in the diagnosis and treatment of cervical spine injuries globally.

1 views • 79 slides

This study by Shyamala Maherswaran, Ph.D., and team focuses on characterizing mutations in EGFR in circulating tumor cells using SARMS assay and CTC-chip. The research investigates the effectiveness of these non-invasive methods in analyzing tumors and explores the role of the T790M mutation in resp

0 views • 12 slides

This informative content delves into the significance, assessment, and clearance of pediatric cervical spine injuries, emphasizing the stratification by age groups and the importance of early evaluation. It highlights the need for spinal clearance in all trauma patients, discusses the immobilization

0 views • 21 slides

This collection of supplementary figures provides detailed flow cytometry data on immune cell populations, including CD4+ T cells, CD8+ T cells, tumor-associated macrophages, and more. The figures also include information on immune checkpoint molecules like PD-L1 and TIGIT. Each figure presents spec

0 views • 4 slides

Vestibular schwannoma, also known as acoustic neuroma, is a common tumor in the cerebellopontine angle. It can be sporadic or associated with neurofibromatosis type 2. Patients typically present with hearing loss and tinnitus, which may be gradual or sudden. Grading systems like Koos, Ojemann, and J

0 views • 75 slides

Neoplasia encompasses abnormal tissue growth that can be benign or malignant. This article explores neoplastic terms, tumor classifications, cancer staging, and genetic factors in cancer development. Gain insights into the characteristics of benign tumors, the biology of cancer including carcinogene

0 views • 29 slides

This tutorial, prepared by the International Working Group for TIL in breast cancer, provides guidelines for pathologists on the standardized evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer based on H&E slides of core biopsies or tumor resections. It details steps such as defini

0 views • 14 slides

Cancer's complex evolution introduces challenges in treatment response. B-SCITE aims to enhance tumor phylogeny inference by integrating bulk sequencing and single-cell data using a probabilistic approach. It addresses the complexity of tumor cell populations and potential treatment failure causes.

0 views • 20 slides

This detailed overview discusses various diagnostic modalities used in spine evaluations, including plain X-rays, X-ray with localization, CT scans, and MRI. Each modality's benefits and applications are explored, aiding in understanding different imaging techniques for spine pathology assessments.

0 views • 20 slides

Spine Surgery is needed for those patients who may have acquired a deformity in the natural alignment of the spine, damage to the intervertebral disc of the spine, impingement of the spinal cord or the nerve roots exiting out of it, congenital birth

1 views • 4 slides

Spine Surgery is needed for those patients who may have acquired a deformity in the natural alignment of the spine, damage to the intervertebral disc of the spine, impingement of the spinal cord or the nerve roots exiting out of it, congenital birth

0 views • 3 slides

Cr(VI)-induced mutagenesis is a key event in the mode of action for small intestinal tumors in mice, with the question of whether it is an essential step in tumor development. The interaction of cellular components with Cr leads to cell proliferation, hyperplasia, and ultimately mutagenesis. Differe

0 views • 4 slides

Protect your spine health with Hind Spine Clinic's guide to better posture at work. Poor posture can lead to chronic back pain, neck strain, and long-term spine issues. Learn tips to maintain proper alignment, reduce strain, and create an ergonomic w

3 views • 4 slides

Say goodbye to spine problems with advanced endoscopic spine surgery at Hind Spine Clinic, Bhopal, Madhya Pradesh. This minimally invasive procedure offers numerous benefits, including faster recovery, minimal medication, no bone removal, reduced ris

3 views • 3 slides