The study delves into the replication crisis in research, citing factors influencing research credibility such as sample size, effect size, and financial interests. It highlights issues like gaming the system, P-hacking, and data sharing reluctance. The growth of Metascience as a response to these c

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HER2 activation plays a crucial role in promoting tumor proliferation and survival in NSCLC. Driven by oncogenic downstream signaling pathways, HER2 overexpression and gene amplification lead to the formation of heterodimers and activation of key signaling cascades. Additionally, HER2 mutations are

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This slideshow provides an overview of tumor classification, nomenclature, and key concepts in pathology. It covers the definitions of neoplasm, tumor, and oncology, the classification of tumors into benign and malignant categories, as well as the importance of stroma in tumor behavior. It also expl

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Discover the best spine tumor treatment at Medspine, the leading hospital with top surgeon and specialist in Medavakkam, Perumbakkam, Royapettah, Chennai.

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The Long-Range Wireless Charging Market has experienced robust expansion, fueled by the proliferation of smart devices and the increasing adoption of electric vehicles (EVs). According to recent studies, the global long-range wireless charging market is estimated to reach $3,279.6 million by 2035, a

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Over the past two decades, there has been a significant proliferation of big data, leading to the emergence of new challenges and opportunities in economic policy formulation. The use of big data, with its three defining characteristics (volume, velocity, and variety), poses questions about the futu

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The growth of the smart speaker market is driven by the growing number of smart homes, the proliferation of multifunctional devices, and the growing demand for voice-activated devices. However, connectivity range issues restrain the growth of this market.

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In the fast-paced digital landscape, where user experience reigns supreme, selecting the appropriate design approach for your website is paramount. With the proliferation of mobile devices, ensuring seamless accessibility across various screen sizes has become a necessity. This brings us to a pivota

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Exploring the diverse ways viruses enter the body through various routes such as respiratory tract, oropharynx, skin, genitourinary tract, and eyes, shedding light on the steps of the virus life cycle shaping pathogenesis. Viral diseases result from the intricate interaction between viral and host f

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The rhizosphere, the region surrounding plant roots, harbors a diverse community of microorganisms influenced by plant roots. Historical background and microbial interactions in the rhizosphere are explored, highlighting the favorable habitat for microbial proliferation and metabolism. Various techn

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The growth of the smart speaker market is driven by the growing number of smart homes, the proliferation of multifunctional devices, and the growing demand for voice-activated devices. However, connectivity range issues restrain the growth of this ma

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Grading and staging are crucial in determining the aggressiveness and extent of malignant tumors. Grading involves assessing the level of malignancy based on cell differentiation and mitotic activity, while staging considers the size of the tumor, lymph node involvement, and presence of metastases.

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Healing or repair by connective tissue occurs in response to severe or chronic tissue injuries, leading to the replacement of nonregenerated cells with connective tissue or scar formation. This process involves the induction of fibroblast and endothelial cell proliferation, granulation tissue format

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Social changes during the early Medieval ages in India were shaped by economic developments, leading to the proliferation of castes and shifts in the positions of Brahmins, Vaishyas, and Shudras. The Brahmins held the highest social position, while Vaishyas were marginalized. The period also saw the

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The MTT cell proliferation assay is a widely used technique to measure cell viability, proliferation, and cytotoxicity in research. This colorimetric assay involves the conversion of MTT reagent to formazan dye by live cells, resulting in a purple color change. This comprehensive guide provides step

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This trial aims to compare the efficacy and safety of molecularly-guided therapy or cancer immunotherapy based on genomic profiling with platinum-based chemotherapy in patients with cancer of unknown primary site. The study design includes multiple treatment regimens guided by genomic profiles, with

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WAGR syndrome is a rare genetic condition associated with Wilms Tumor, aniridia, and developmental delays. Wilms Tumor is a form of kidney cancer mostly affecting children and is linked to genetic disorders like WAGR syndrome. The risk of Wilms Tumor is higher in children with WAGR syndrome, with po

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Positron Emission Tomography (PET) is a medical imaging technique focusing on metabolic differences in the body. By using positron-emitting radioisotopes, PET can detect how molecules are taken up by healthy and cancerous cells, aiding in accurate tumor localization with lower doses. The evolution o

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Research collaboration aimed to enhance locoregional tumor control and reduce distant failure by combining charged particles irradiation and anticancer drug Epothilone B in cultured human tumor cells from Milano and Roma. The study explores the impact on clonogenic survival, growth curves, and deter

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The Gamma Knife Stereotactic Radiosurgery is a precise and effective treatment method where highly focused radiation beams are used to target tumors and abnormalities in the brain. It does not remove the tumor directly but affects DNA, cell growth, and blood vessels. The procedure involves three mai

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NCI-MATCH is a groundbreaking clinical trial aiming to match tumor gene alterations with targeted therapies. The interim analysis results revealed impressive patient enrollment and site participation exceeding expectations. Despite challenges with pausing new patient registrations for the analysis,

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This content discusses the management and proliferation of DEERS data within the Military Health System (MHS). It covers how DEERS data are maintained, who is included in the data, data upkeep processes, strengths and weaknesses, data proliferation throughout the MHS, added value of MDR processing,

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The body's response to injury involves two main processes of wound healing - regeneration and repair. Regeneration involves proliferation of parenchymatous cells, while repair results in fibrosis and scarring by proliferation of connective tissue. Different types of cells play varying roles in the h

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Detailed overview of the measures implemented for verifying states' compliance with the Nuclear Non-Proliferation Treaty (NPT), including design verification, analysis of declarations, on-site inspections, assay of nuclear materials, and containment/surveillance techniques. The process involves dest

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This study by Shyamala Maherswaran, Ph.D., and team focuses on characterizing mutations in EGFR in circulating tumor cells using SARMS assay and CTC-chip. The research investigates the effectiveness of these non-invasive methods in analyzing tumors and explores the role of the T790M mutation in resp

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Exploring the risks associated with chemical and biological weapons proliferation, covering topics such as war scenarios, terrorism, dual-use issues, international conventions, and emerging threats. This includes discussions on the use of toxic chemicals in various settings, along with examples of p

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The international regime for nuclear disarmament and non-proliferation faces challenges from states within and outside the regime, as well as non-state actors. Various approaches are being utilized to address these challenges, including strengthening multilateral institutions, non-treaty-based multi

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This collection of supplementary figures provides detailed flow cytometry data on immune cell populations, including CD4+ T cells, CD8+ T cells, tumor-associated macrophages, and more. The figures also include information on immune checkpoint molecules like PD-L1 and TIGIT. Each figure presents spec

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Vestibular schwannoma, also known as acoustic neuroma, is a common tumor in the cerebellopontine angle. It can be sporadic or associated with neurofibromatosis type 2. Patients typically present with hearing loss and tinnitus, which may be gradual or sudden. Grading systems like Koos, Ojemann, and J

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Neoplasia encompasses abnormal tissue growth that can be benign or malignant. This article explores neoplastic terms, tumor classifications, cancer staging, and genetic factors in cancer development. Gain insights into the characteristics of benign tumors, the biology of cancer including carcinogene

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Understanding the classification of tumors is crucial in the field of pathology. This detailed overview covers the definitions of neoplasia and tumors, the differentiation between benign and malignant tumors, nomenclature, and characteristics of various tumor types. It discusses the behaviors of ben

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Device proliferation and adoption of BYOD policies in SMB non-profits pose significant security challenges, such as encryption, password policies, data mixing, legal discovery, remote wiping, and security attestation. Neglecting these issues can lead to severe consequences, as illustrated by a case

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This tutorial, prepared by the International Working Group for TIL in breast cancer, provides guidelines for pathologists on the standardized evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer based on H&E slides of core biopsies or tumor resections. It details steps such as defini

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Craniopharyngioma is a complex intracranial tumor with a rich historical background dating back to the early 20th century. Initially described by McLean, Frazier, Alpes, and famously studied by Cushing, this tumor continues to be a subject of debate and controversy in terms of treatment approaches a

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This study explores the problem of finding the largest area axis-aligned B-empty rectangle containing n red points and m blue points. The research discusses various extensions to the original problem, such as the Blue Rectangles problem and the Outliers Problem, aiming to achieve efficient solutions

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The European Network of independent non-proliferation think tanks, known as the Consortium, aims to combat the spread of weapons of mass destruction and enhance awareness through various activities such as expert meetings, conferences, reports, and e-learning courses. The Consortium works closely wi

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Exploring the role of the Non-Proliferation Treaty (NPT) in nuclear renunciation decisions, this study investigates the relationship between global nuclear abstinence and the NPT through a case study of Ukraine, Belarus, and Kazakhstan from 1990-1994. It delves into the challenges of Soviet dissolut

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Cancer's complex evolution introduces challenges in treatment response. B-SCITE aims to enhance tumor phylogeny inference by integrating bulk sequencing and single-cell data using a probabilistic approach. It addresses the complexity of tumor cell populations and potential treatment failure causes.

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Learn about the eligibility requirements for sitting for the Certified Tumor Registrar (CTR) examination, which include formal education and experience. Discover the different paths to meeting the eligibility criteria, such as obtaining an Associate's Degree in Cancer Registry Management or gaining

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Cr(VI)-induced mutagenesis is a key event in the mode of action for small intestinal tumors in mice, with the question of whether it is an essential step in tumor development. The interaction of cellular components with Cr leads to cell proliferation, hyperplasia, and ultimately mutagenesis. Differe

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