Neonatal data plays a crucial role in assessing the quality of care provided to newborns in the UK. This resource from the National Neonatal Research Database at Imperial College London sheds light on how neonatal data is collected, utilized, and shared among healthcare professionals. The importance

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The Age-Friendly app addresses the crucial issue of drug-drug interactions between current prescriptions and over-the-counter analgesics in the geriatric population. With a significant percentage of OTC sales attributed to older adults, there is an increased risk of adverse drug events due to polyph

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Neonatal jaundice, a common condition in newborns, results from elevated bilirubin levels. While often benign, high levels can lead to complications like kernicterus. Recognizing risk factors, limitations of clinical assessment, and appropriate evaluation and treatment are crucial in managing neonat

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Neonatal and postnatal diseases in livestock, with a focus on perinatal, neonatal, and postnatal stages. It covers common classifications, causes, and risk factors associated with these diseases, particularly focusing on neonatal diarrhea (Calf Scour). The content delves into noninfectious and infec

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Drug regulation involves controlling drug use through international agreement authorities like the FDA, EMA, and PMDA. The FDA plays a crucial role in drug evaluation and research, biologic evaluation, devices, and food safety. There are various types of applications for drug approval, along with a

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Dive into the world of neonatal data with Catherine Nash, where the focus lies on the importance of collecting and utilizing data effectively to enhance care standards for babies and families. Discover how data systems like BadgerNet play a vital role in monitoring care, diagnosing treatments, measu

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Polymeric controlled drug delivery systems play a crucial role in regulating drug release through diffusion, solvent penetration, and chemical mechanisms. These systems include diffusion-controlled, solvent-controlled, and chemically-controlled devices, each operating based on specific principles. S

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This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID

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Dive into Session 7 of the ARIDE program to explore the prevalence of drug and alcohol use, the concept of polydrug impairment, and the potential effects of combining different substances. Learn about null effects, overlapping effects, and how various drug combinations can impact impairment indicato

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Nasopulmonary drug delivery system, utilizing the nasal route for drug administration, offers advantages such as hepatic first-pass metabolism avoidance and rapid drug absorption. This system is beneficial for pharmacologically active compounds with poor stability in gastrointestinal fluids. While i

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The physicochemical properties of drugs play a crucial role in their pharmacological effects. These properties include physical and chemical characteristics that influence interactions with biomolecules. Solubility, partition coefficient, and dissociation constant are key factors affecting drug beha

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This resource provides a comprehensive toolkit developed by the British Association of Perinatal Medicine in collaboration with the National Neonatal Audit Programme to assist clinicians in neonatal units in delivering normothermia to very preterm infants. It includes evidence-based interventions, d

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The Maternity and Neonatal Safety Improvement Programme aims to enhance the quality and safety of maternity and neonatal units in England by reducing rates of maternal and neonatal deaths, stillbirths, and brain injuries. Through system-level project updates and regional collaborative efforts, the p

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Gain insights on frequently used medications in the perioperative period for infants and children, including anesthesia medications. Explore pharmacokinetics, drug distribution in neonates, and the effects of common anesthesia agents on pediatric patients. Understand how immature kidney or liver fun

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Lagos University Teaching Hospital (LUTH) is a tertiary referral center providing comprehensive neonatal care services. The facility has specialized units for inborn and outborn babies, offering advanced medical care, including neonatologists, resident doctors, nurses, and support staff. LUTH also h

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Renal block plays a crucial role in drug excretion, with processes like glomerular filtration and tubular secretion affecting drug elimination. Factors like blood flow, physiochemical properties, and urine pH influence renal excretion of drugs. Competition between drugs for transporters can have ben

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This presentation by Dr. Khalid Altirkawi, M.D., Assistant Professor of Pediatrics, aims to educate medical students on neonatal jaundice. The content covers metabolic pathways of bilirubin, types of jaundice, diagnostic tests, prevention, and treatment strategies. It provides valuable insights into

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In drug development, in-vitro dissolution testing plays a crucial role in evaluating drug release from tablets when in-vivo bioavailability studies are limited. By ensuring drug release is close to 100% and uniform batch to batch, these tests help assess drug availability and effectiveness. Regulato

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Pharmacodynamics explores how drugs interact with receptors in the body, affecting the magnitude of drug effects based on concentration. Graded dose-response relationships, potency, and efficacy play key roles in determining drug efficiency. Potency reflects the amount of drug needed for a specific

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Explore the quantitative aspects of drug action, including drug receptor binding, concentration binding curves, dose-response curves, and types of antagonism. Learn to relate drug concentration to receptor binding capacity and response produced. Discover how concentration binding curves and dose-res

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Neonatal Abstinence Syndrome (NAS) is a condition where infants experience withdrawal symptoms from exposure to drugs in utero, with a significant impact seen in regions like southeastern Kentucky due to the opioid crisis. This syndrome manifests through various short and long-term effects, necessit

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Drug abuse is a serious issue involving various substances like prescription drugs, alcohol, and illegal drugs. This includes terms and definitions, effects on the body and mind, stages of addiction, and withdrawal symptoms. Factors influencing drug action and reasons for drug use are also explored.

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Neonatal seizures are sudden changes in neurologic function of a newborn, involving motor, behavior, and autonomic functions. The pathophysiology includes delays in Na/K ATPase maturation, increased receptor density, and GABAergic transmission. Different types of seizures like subtle, clonic, tonic,

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The Neonatal BCG Programme has undergone changes, including shifting the timing of the BCG vaccine administration from birth to 28 days and introducing Severe Combined Immunodeficiency (SCID) evaluation. This session aims to educate on the modifications for safe practice. The BCG immunization progra

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The neonatal period, also known as the newborn stage, encompasses the first 28 days of a baby’s life, characterized by rapid changes and fragility. This crucial stage requires specialized care, with sub-divisions such as the Period of the Partunate and Period of the Neonate. Commonly, neonates may

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Under-5 mortality rates are showing improvement, yet neonatal mortality lags behind. Addressing this requires a focus on neonatal care, particularly through the implementation of IMNCI protocols. The use of IMNCI can enhance the management of sick newborns, reduce neonatal deaths, and improve overal

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The data highlights key components, operational aspects, major causes, and timing of maternal and neonatal deaths. It emphasizes the critical period around delivery for both mothers and babies, stressing the need for interventions during this vulnerable time to reduce mortality rates. The informatio

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Decision-to-Delivery Interval (DDI) study at Thika Level 5 Hospital examined 419 EMCS cases. The median DDI was 248 minutes, with 91.6% exceeding 75 minutes. Maternal complications were 6%, neonatal complications included MAS, RDS, birth asphyxia, and perinatal deaths. Prolonged DDI was associated w

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This project focused on reintroducing transitional care within the Maternity and Neonatal Service at NHS Ayrshire and Arran, aiming to enhance family satisfaction, reduce term admissions to the Neonatal Unit, and improve the overall care provided to families. Key strategies included changes in ward

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Neonatal Admission Study led by Dr. Rachel Rowe aims to investigate the admission of babies to neonatal care following birth in midwifery units. The study focuses on identifying risk factors and potential improvements in outcomes. The case-control study involves monthly data collection for 12 months

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The World Drug Report 2020 highlights the strong correlation between socioeconomic factors and drug use disorders. Studies reveal that communities facing poverty, violence, and social inequality are at a higher risk of drug overdoses and addiction. Factors like income inequality, lack of social capi

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Neonatal seizures are a critical sign of neurologic dysfunction in newborns, with various types such as subtle, clonic, tonic, spasms, and myoclonic seizures. The immature brain's excitability and differences from the mature brain predispose neonates to seizures. Generalized clonic seizures are rare

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Key Club and UNICEF are collaborating through Trick-or-Treat for UNICEF to help eradicate Maternal and Neonatal Tetanus (MNT). This initiative has raised over $175 million since 1950. Maternal/Neonatal Tetanus affects millions globally due to unsanitary birthing conditions. Learn how to get involved

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Targeted clinical investigation plays a crucial role in pharmacovigilance by further evaluating significant risks identified in pre-approval clinical trials. This involves conducting pharmacokinetic and pharmacodynamic studies, genetic testing, interaction studies, and large simplified trials to ass

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Neonatal Abstinence Syndrome (NAS) is a condition where infants experience withdrawal symptoms from substances they were exposed to before birth. This syndrome is a consequence of the opioid crisis, leading to prolonged hospitalizations and long-term effects. By defining NAS, listing common behavior

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This content explores various advanced ophthalmic drug delivery systems including erodible ophthalmic inserts, soluble ocular drug inserts, new ophthalmic drug delivery systems, and bioadhesive ophthalmic drug inserts. These innovative systems aim to provide accurate dosing, prolonged drug release,

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Proposal presentation at HESI Annual Meeting discusses challenges in neonatal therapeutics, including off-label drug use in NICU, low clinical relevance in studies, and barriers to conducting neonatal trials. Mandates require inclusion of neonates in pediatric studies, but priorities and study desig

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Center for Court Innovation has introduced a new National Drug Court Online Learning System aimed at assisting drug court professionals. This system offers free access to web-based training, expert video lessons, virtual site visits to drug treatment courts, practitioner interviews, and a resource l

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This initiative aims to improve the safety and outcomes of maternal and neonatal care in England by reducing unwarranted variations, providing high-quality healthcare experiences, and enhancing systems and processes for better care. Key focuses include promoting smoke-free pregnancies, optimizing ca

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The Drug-Free Workplace Act of 1988 mandates federal grant recipients to implement zero-tolerance drug policies to maintain a drug-free environment. Employers must establish clear policies, conduct awareness programs, offer counseling and rehabilitation services, and impose penalties for violations.

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