Role of High-Resolution Computed Tomography in Fibrosing Interstitial Lung Diseases
HRCT plays a crucial role in diagnosing and monitoring fibrosing interstitial lung diseases (ILDs). It helps identify abnormalities not visible on X-rays, leading to early, accurate diagnoses and potentially avoiding invasive procedures. HRCT assists in distinguishing specific ILDs based on radiogra
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Overview of Jaw Cysts: Classification and Clinical Features
A cyst in the jaw is a fluid-filled cavity lined by epithelium that commonly occurs in the jawbones. There are different types of jaw cysts, such as odontogenic cysts and non-odontogenic cysts, each with specific clinical features and radiographic appearances. Understanding the classification and fe
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APPROACH TO THE TREATMENT OF INFLAMMATORY POLYARTHRITIS
Inflammatory polyarthritis can have various causes, including infections, systemic rheumatic diseases, crystal-induced arthritis, vasculitides, and more. Dr. Afsar Sayeeda, a consultant internist and rheumatologist, emphasizes early diagnosis and intervention in conditions like rheumatoid arthritis
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Podiatrist's Role in Managing Foot Involvement in Rheumatic Diseases
Rheumatology encompasses over 200 conditions affecting the musculoskeletal system, with foot involvement being significant in conditions like RA and OA. Podiatrists play a crucial role in diagnosing, treating, and preventing foot problems associated with inflammatory arthritis, such as joint damage,
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Hannah's Struggle with Inflammatory Bowel Disease: A Journey of Challenges and Lessons
Hannah, a vibrant young woman with a bustling social life and active routines, experiences a series of setbacks in her battle with Inflammatory Bowel Disease (IBD). Her journey highlights the importance of timely diagnosis, access to proper care, and comprehensive support services to manage the cond
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Understanding Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Their Pharmacology
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of analgesic, antipyretic, and anti-inflammatory medications that work by inhibiting prostaglandin synthesis. They provide relief from pain, reduce fever, and combat inflammation through various mechanisms. Aspirin, a commonly used NSAID, irr
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Understanding Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Types and Classification
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are a diverse group of medications with analgesic, anti-inflammatory, and antipyretic properties. They act primarily on peripheral pain mechanisms and vary in their selectivity of COX inhibition. This article explores the history, classification, and se
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Overview of Chemical Mediators of Inflammation and Their Roles
Chemical mediators of inflammation act on blood vessels and cells to contribute to an inflammatory response. These mediators include vasoactive amines like histamine and serotonin, plasma proteases such as the complement, kinin, and clotting systems, and important inflammatory mediators like C3a and
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Understanding C-Reactive Protein (CRP) Test: Uses and Principle
C-Reactive Protein (CRP) is a liver-produced protein that indicates inflammatory conditions. The CRP test helps detect infections, monitor diseases like cancer, and evaluate inflammatory conditions. The test principle involves latex agglutination for CRP detection in human serum.
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Residual Inflammatory and Cholesterol Risks in Atherosclerosis Patients
In a secondary analysis of the CANTOS study, researchers evaluated the impact of residual inflammatory risk and residual cholesterol risk in a large cohort of atherosclerosis patients already receiving lipid-lowering therapy. Results showed the relative contributions of inflammation and cholesterol
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Understanding Nasmyth's Membrane and Dentigerous Cysts in Dental Health
Nasmyth's Membrane is a residue found on newly erupted teeth, causing extrinsic staining. It can be treated with selective polishing and proper brushing. Dentigerous cysts, odontogenic cysts associated with developing teeth, may lead to dental issues. Treatment for cysts includes monitoring and, if
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Chemical Mediators of Inflammation: Understanding Sources and Effects
Chemical mediators of inflammation play a pivotal role in inducing specific events during acute inflammation. These mediators are produced in response to various triggers, including microbial products and host proteins, leading to a cascade of inflammatory responses. Understanding the sources and ef
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Understanding Arthritis: Diagnosis and Pathophysiology
Joint pain can result from various factors such as inflammation, cartilage degeneration, crystal deposition, infection, or trauma. Different pathophysiologic processes necessitate clinical evaluation and identification through history, physical examination, and understanding of joint disease types.
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Understanding the Peritoneum: Structure, Functions, and Inflammatory Responses
The peritoneum, a vital membrane in the body's abdominal cavity, consists of visceral and parietal components with distinct pain perceptions. It plays crucial roles in lubrication, fluid absorption, immune responses, and more. Peritoneal inflammatory exudate can result from various causes such as ba
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Overview of Inflammatory Diseases of Bone
Inflammatory diseases of bone encompass conditions like osteitis, osteomyelitis, periostitis, and alveolar osteitis (dry socket). Osteitis is localized and may be associated with infected sockets, while osteomyelitis involves the interior of the bone. Alveolar osteitis commonly follows tooth extract
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Understanding Odontogenic Cysts in Maxillofacial Region
Odontogenic cysts may occur centrally within bones of the maxilla and mandible, predominantly in tooth-bearing areas. Types include radicular cysts, residual cysts, and dentigerous cysts, each with distinct radiographic features and epicenter locations. Radicular cysts are commonly found around nonv
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Overview of Giardia lamblia Parasite and Giardiasis Disease
Giardia lamblia, also known as Giardia intestinalis, is a flagellated parasitic microorganism that causes giardiasis by colonizing the small intestine. It infects humans, cats, dogs, and birds, and is a common parasitic human disease globally. Giardiasis, popularly known as beaver fever, can lead to
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Overview of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in Veterinary Pharmacology
Non-steroidal anti-inflammatory drugs (NSAIDs) are a diverse group of medications with analgesic, anti-inflammatory, and antipyretic effects. They act primarily on peripheral pain mechanisms and have limited CNS effects. NSAIDs have a long history dating back to the use of White Willow bark, and the
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Management of Inflammatory Psychiatric Disease with Focus on PANS in Pediatric Patient
Dr. Margo Thienemann discusses the psychiatric medication management of a 10-year-old boy with inflammatory psychiatric disease, particularly focusing on Pediatric Acute-onset Neuropsychiatric Syndrome (PANS). The patient presented with various symptoms including compulsions, mood swings, OCD, oppos
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Understanding Anti-Inflammatory Foods and Immune Function
Our health is closely linked to the gut microbiome, with fiber playing a key role in feeding beneficial gut bacteria. Incorporating anti-inflammatory polyphenols from plant-based sources like fruits, vegetables, and herbs can promote a healthier gut. Additionally, fermented foods act as natural prob
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Understanding Choledochal Cysts: A Congenital Anomaly of the Biliary Tract
Choledochal cysts are congenital anomalies of the biliary tract characterized by cystic dilatation at various segments. They can lead to complications like biliary cirrhosis and recurrent pancreatitis. Clinical features include jaundice, abdominal pain, and right epigastric mass. Early detection is
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Understanding Neck Swellings and Cysts
Explore the anatomy of neck muscles, main categories of neck swellings, and different types of cysts like ranula, dermoid cyst, and thyro-glossal cyst. Learn about their characteristics, locations, and treatment options. Visual aids included.
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Comprehensive Overview of Jaw Imaging Modalities and Pathologies
Comprehensive overview detailing jaw imaging modalities such as X-Ray, CT, and MRI for evaluating jaw bone and tooth conditions. Covers anatomy, common mandibular lesions, odontogenic cysts, non-odontogenic cysts, and odontogenic benign tumors. Provides details on diagnostic protocols, imaging findi
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Understanding Reproductive Disorder Diseases and Hormonal Infertility in Simple Language
Reproductive disorders can lead to infertility or sterility in animals, affecting their ability to reproduce. Causes include anatomical, functional, infectious, and management factors. Hormonal infertility may result from issues like cystic ovaries, delayed ovulation, or inactive ovaries. Conditions
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HerboJoint: Natural Formulation for Joint Pain Relief
Bordoloi Biotech India Pvt Ltd presents HerboJoint, a unique natural formulation designed to provide freedom from joint pain. Developed by a team of experts led by Dr. Binoy B. Bordoloi and Dr. Kulwant S. Saini, HerboJoint is a scientifically backed product combining essential oils with proven effic
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Understanding Burn Wounds: Pathophysiology and Classification
Burn injuries, such as burns and scalds, are complex inflammatory conditions caused by exposure to heat, chemicals, or electricity. This article delves into the pathophysiology of burn wounds, explaining how tissue damage occurs and the classification of burn depths based on layers of skin affected.
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Understanding Cryptococcal Immune Reconstitution Inflammatory Syndrome
Cryptococcal Immune Reconstitution Inflammatory Syndrome (C-IRIS) is a condition where rapid reversal of immunodeficiency triggers exaggerated inflammatory reactions in response to Cryptococcus antigens. It can manifest as either Unmasking IRIS or Paradoxical IRIS, with common CNS presentations incl
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Understanding the Role of Vitamin D in Reducing COVID-19 Risk
Vitamin D plays a crucial role in reducing the risk of COVID-19 by enhancing the body's immune response, reducing production of pro-inflammatory cytokines, and increasing anti-inflammatory cytokines. Individuals at greater risk include the elderly, those with chronic diseases, dark-skinned individua
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Understanding Pterygium: Degenerative or Inflammatory Change?
Pterygium, a common ocular surface lesion, has historically been considered degenerative due to factors like UV radiation exposure. However, recent research suggests an inflammatory component with cellular proliferative fibrosis and angiogenesis. This study presented at TOSCON 2024 delves into the h
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Understanding the Inflammatory Response Mechanism
The inflammatory response is a crucial defense mechanism of the immune system. It comprises three lines of defense aimed at protecting the body from harmful pathogens. When a barrier is breached, such as by a splinter carrying bacteria, the inflammatory process is initiated. This includes the releas
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Impact of Raft Association of NF155 on Microglial Cells' Inflammatory Response
Multiple sclerosis (MS) is a neurodegenerative disease affecting millions globally by causing myelin loss in the CNS axons. This study investigates the role of NF155 raft association in the inflammatory response of microglial cells, shedding light on potential treatment strategies for MS. Liposome t
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Overview of Common Surgical Liver Diseases and Portal Hypertension
The liver plays a crucial role in metabolism, coagulation, and immune function. Surgical diseases of the liver, such as liver cysts and cavernous haemangiomas, can impact its normal functions. Imaging modalities like ultrasound (US), CT scans, and MRI are essential for diagnosing and staging liver t
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Comprehensive Overview of Salivary Gland Diseases and Management
Salivary gland diseases encompass various conditions affecting the salivary glands, including developmental abnormalities, inflammatory and non-inflammatory enlargement, cysts, tumors, and dysfunction. Investigations such as plain films, sialography, MRI, and biopsies are essential for diagnosis. Si
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Understanding Inflammatory Bowel Disease: Crohn's Disease and Ulcerative Colitis
Inflammatory Bowel Disease (IBD) encompasses Crohn's disease (CD) and ulcerative colitis (UC), chronic conditions with immunologic basis. This article delves into the epidemiology, pathophysiology, and differences between CD and UC, highlighting clinical features, pathology, and complications like a
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Inflammatory Bowel Disease Case Study: Diagnostic Challenges and Treatment Decision
A 56-year-old male with a history of inflammatory bowel disease presented with severe symptoms necessitating hospitalization. Despite steroid therapy, lack of improvement led to consideration of a total colectomy. Colonoscopy and biopsy results favored ulcerative colitis over Crohn's disease. This c
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Understanding Inflammatory Disorders of the Cardiovascular System
Inflammatory conditions of the heart, such as pericarditis and myocarditis, can have various causes and manifestations. Pericarditis can present as fibrinous, purulent, or hemorrhagic, each with distinct characteristics and implications. Myocarditis, on the other hand, can result from infections lik
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Understanding Purpura and Vasculitis: A Comprehensive Guide
Explore the differentiation between types of purpura, inflammatory and non-inflammatory distinctions, diagnosis of purpuric lesions, serious vs. non-serious conditions, causes of purpura, and an overview of vasculitis including its manifestations in large, medium, and small vessels with a focus on c
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Outcomes of Parastomal Hernia Repair in Inflammatory Bowel Disease Patients
This study examines the outcomes of parastomal hernia repair in patients with inflammatory bowel disease, specifically comparing outcomes between those with Crohn's disease and ulcerative colitis. The research, conducted from 2012 to 2022, analyzes data from 392 patients, highlighting factors such a
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Management of Immune Reconstitution Inflammatory Syndrome (IRIS) Guidelines
This guideline provides recommendations for managing Immune Reconstitution Inflammatory Syndrome (IRIS) in patients undergoing Antiretroviral Therapy (ART). It covers terminology, treatment recommendations, initiating ART, key points, and emphasizes not interrupting ART except in life-threatening ca
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Understanding Acute and Chronic Inflammation: Causes, Outcomes, and Resolution
Acute inflammation results in either resolution or progression to chronic inflammation, with outcomes like restoration of normalcy, fibrosis, or scarring. Chronic inflammation can be caused by viral infections, persistent microbial infections, exposure to toxic agents, or autoimmune diseases. Macrop
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