This clinical update presents the 2023 ACC/AHA/ACCP/HRS guideline for diagnosing and managing atrial fibrillation. It categorizes recommendations based on class of recommendation and level of evidence, ranging from strong to weak. Recommendations are supported by high-quality evidence from randomize

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In a follow-up analysis of the EARLY-AF trial, patients with paroxysmal atrial fibrillation were studied after cryoablation or antiarrhythmic drug therapy. Results showed lower incidence of persistent atrial fibrillation in the ablation group over 3 years, with fewer adverse events. Atrial fibrillat

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This study details the principal results of the RELIEVE-HF trial, investigating the safety and effectiveness of the V-Wave Ventura interatrial shunt device in patients with heart failure with reduced and preserved ejection fraction. Key inclusion and exclusion criteria are outlined, emphasizing the

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This clinical update provides recommendations for the diagnosis and management of atrial fibrillation adapted from the 2023 ACC/AHA/ACCP/HRS guidelines. It includes information on class strength of recommendations, levels of evidence, and phrases for writing recommendations based on the quality of e

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A prespecified subanalysis of the NOAH-AFNET 6 trial evaluated the efficacy and safety of edoxaban anticoagulation in patients with Atrial High-Rate Episodes (AHRE) lasting 24 hours compared to shorter episodes. Findings suggest that oral anticoagulation with edoxaban does not significantly reduce t

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This informative content covers the current practice guidelines and medication options for antiplatelet therapy in CAD patients, discussing different medications, optimal duration of therapy, CV risk assessment, and anticoagulation options in atrial fibrillation. It delves into the role of aspirin i

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Anti-arrhythmic agents are crucial in managing abnormal heart rhythms like atrial fibrillation and ventricular tachycardia. Causes of arrhythmias vary from heart anatomy changes to medication side effects. Factors like exertion, imbalances in blood chemistry, and medication use can trigger arrhythmi

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Dr. Mona Soliman, MBBS, MSc, PhD from King Saud University explains the waves, intervals, and leads of a normal ECG in detail. The ECG records the heart's electrical activity, showcasing depolarization and repolarization waves. Learn about P-wave (atrial depolarization), QRS complex (ventricular dep

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Digoxin, a cardiac glycoside, is utilized in managing congestive heart failure and atrial fibrillation due to its inotropic and chronotropic effects on the heart. It functions by inhibiting Na,K-ATPase, leading to increased intracellular calcium concentrations and augmented myocardial contractility.

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A study conducted in Sweden on 182,678 patients with atrial fibrillation aimed to investigate risk factors for stroke and bleeding. The research assessed the application of CHA2DS2-VASc and HAS-BLED schemes for stroke and bleeding risk evaluations. Data from the Swedish Atrial Fibrillation cohort st

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A study by DJ Graham et al. compared the risks of stroke, bleeding, and mortality in elderly Medicare beneficiaries with nonvalvular atrial fibrillation treated with dabigatran or rivaroxaban. The study included over 118,000 patients and found that dabigatran was associated with a lower risk of majo

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Heart failure is a condition where the heart struggles to pump blood efficiently, leading to various complications. It can affect different sides of the heart, with causes ranging from coronary artery disease to valve problems. Congenital heart diseases, on the other hand, are common anomalies prese

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The data report examines the prevalence of cardiovascular diseases in adult End-Stage Renal Disease (ESRD) patients in 2016 by treatment modality and age. It includes information on various cardiovascular conditions such as atrial fibrillation, acute myocardial infarction, coronary artery disease, a

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Dr. Shiuli from KGMU specializes in Forensic Medicine & Toxicology, focusing on the impact of electrical injuries such as ventricular fibrillation, thermal injuries, and post-mortem findings like external marks and histological changes. Detailed insights on path of current, causes of death, flash bu

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The PRAGUE-17 study compares the three-year outcomes of left atrial appendage closure (LAAC) versus direct oral anticoagulation in patients with atrial fibrillation. LAAC was found to be non-inferior to NOACs for the primary composite endpoint, with similar incidence rates for secondary endpoints. T

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Ascidians, also known as sea squirts, exhibit retrogressive metamorphosis where the larval stage possesses advanced features lost in adulthood. With a tough outer tunic, these marine filter feeders have three main types - solitary, social, and compound ascidians. They feed by taking in water through

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Heart Failure (HF) is increasingly recognized as a cause of Atrial Fibrillation (AF). The goals of individualized therapy for AF include ventricular rate control, restoration of sinus rhythm, maintenance of sinus rhythm, and prevention of stroke. Hemodynamically unstable AF requires emergent convers

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Cardiovascular complications of thalassaemia can be categorized into iron overload-related issues such as myocyte failure and arrhythmias, and non-iron overload complications including pulmonary hypertension and atrial fibrillation. Cardiac iron accumulation poses a significant risk, leading to card

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A thorough exploration of perioperative bridging anticoagulation in patients with atrial fibrillation, discussing the benefits of anticoagulation, therapeutic options, comparison of literature, and application in moderate-risk patients. The use of warfarin in atrial fibrillation treatment, standard

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Congenital heart diseases are abnormalities in the heart's structure present at birth. Factors like viral infections, genetic conditions, and maternal health contribute to these conditions. There are non-cyanotic and cyanotic classifications based on shunting patterns. Examples include atrial septal

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Dive into the realm of cardiac anticoagulation, exploring the evolution from traditional methods like Warfarin to the modern use of Novel Oral Anticoagulants (NOACs). Discover the indications for long-term anticoagulation in conditions like atrial fibrillation and mechanical heart valves. Delve into

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The heart controls its own beat through the cardiac cycle initiated by the Sinoatrial node (SA node). This myogenic system allows the heart to contract and relax without the need for external impulses. The cardiac muscle responds to electrical waves, leading to synchronized contractions of the atria

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This study aims to characterize the plasma levels of Dabigatran, Rivaroxaban, and Apixaban in patients with non-valvular atrial fibrillation (NVAF) who have been taking these drugs for more than 4 days. The research also assesses median trough plasma levels of these anticoagulants, as well as their

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