000 genomes project - PowerPoint PPT Presentation


Insights into Genome Assembly and Shotgun Sequencing

Explore the world of genome assembly, shotgun sequencing, and the fundamental concepts behind deriving genomes from large sets of sequencing reads. Learn about the complexity and core algorithms involved in contemporary genome assembly processes. Discover how the shotgun concept has revolutionized g

2 views • 66 slides


Strategic Digital Initiative Presentation for ECONUM Project

This presentation outlines the strategy and responsible approach for the digital transformation of the ECONUM project. It includes details on the project's objectives, mandatory requirements for project submission, contact information for organizing submission meetings, and key considerations for pr

10 views • 15 slides



Investigating Human Papillomavirus Genomes in Cervical Neoplasms

This project focuses on studying the Human Papillomavirus (HPV) genome's association with disease progression and treatment response in cervical neoplasms and cancer. The research aims to genotype high-risk HPVs in healthy and diseased cervix, identify prevalent genotypes, detect genotype drift, cha

1 views • 13 slides


Pursuing a medical degree in Madhya Pradesh.

Excellent medical colleges like AIIMS Bhopal, MGMMC Indore, and NSCBMC Jabalpur make Madhya Pradesh a great choice for those pursuing a career in medicine. The government offers good education, low-cost fees, and a lot of hands-on experience at hospitals. Public colleges have yearly fees between INR

1 views • 5 slides


Explore BDS, MDS Nursing courses at Maitri Dental College, Durg

BDS ADMISSION 2024\nEligibility Criteria : NEET Qualified Tuition Fees: 2 Lac Annually\nHostel Fees: 60,000\/- Annually\n\nMDS ADMISSION 2024\nEligibility : PG-NEET Qualified\n5Clinical & 3Non-Clinical Branches\nHostel Fees: 1,00,000\/- Annual\n\nBSC NURSING\nDuration : 4 years\nTuition Fees: 70,000

0 views • 12 slides


Genetic Control of Metabolism in Microbes: Enhancing Traits for Biotechnology

Exploring the genetic control of metabolism in microbes, focusing on wild type organisms and the process of strain improvement through mutagenesis, selective breeding, and recombinant DNA techniques. The potential benefits and challenges of altering microbial genomes for biotechnological application

0 views • 27 slides


Transformative Power of Sequencing in Molecular Biology

The falling costs of sequencing have revolutionized various fields like genetics, genomics, cell biology, microbiology, and evolutionary biology. Sequencing data has enabled us to understand genomes, revolutionize cell biology techniques, conduct comparative genomics, population genomics, and metage

1 views • 31 slides


The Origin of Viruses: Theories and Evidence

Viruses are acellular parasites with a complex replication mechanism. Studies on their origin present challenges due to the lack of fossils. Three main hypotheses include regressive, cellular origin, and co-evolution. The regressive hypothesis suggests viruses originated from complex ancestors that

2 views • 25 slides


Rounding Numbers and Identifying Nearest Multiples Practice Sheets

Practice rounding numbers to the nearest 10, 100, and 1,000, as well as identifying the nearest multiples of 10,000, 100,000, and 1,000,000. Complete tables, match numbers to their nearest values, and understand the concept of rounding within different ranges. Improve your math skills with these eng

0 views • 14 slides


Understanding Transcription Factors and Regulatory Sequences in Gene Expression

Transcription factors play a crucial role in gene expression by controlling the recruitment of RNA polymerase. Promoter regions contain sequences like CAAT box and TATA box that regulate transcription by binding proteins. Consensus sequences are conserved patterns in the genome with various biologic

2 views • 10 slides


Viral Genome Replication Strategies and Mechanisms

Viruses utilize different replication strategies to ensure the replication of viral genomes, packaging into virions, and potentially altering the host cell's structure or function. These strategies are vital for the virus to operate effectively within the host cell's constraints. The replication pro

0 views • 15 slides


Understanding Transcription and Translation of Virus Genome

The lecture covers the transcription and translation processes of virus genomes, including the Baltimore classification system, transcription control in eukaryotes, and the role of transcription factors in gene expression. It explores how different viruses replicate based on their genome type and me

0 views • 14 slides


sap fees

A SAP Consultant Salary in India earns between \u20b93,50,000 and \u20b96,00,000 per annum at entry-level, \u20b96,00,000 to \u20b912,00,000 at mid-level, and \u20b912,00,000 to \u20b925,00,000 with over five years of experience. To maximize earning

0 views • 5 slides


Efficient User Management System for Health Facilities

Record and manage user details effectively with the new Version 2.0 User Management feature. RNTCP has now registered over 35,000 PHIs, 140,000 Private Health Facilities, 15,000 Private Labs, 31,000 Private Chemists, across 700 Districts and 8,000 TUs in Nikshay. Enhance operations by editing TU pro

0 views • 26 slides


Exploring the Evolution of Molecular Biology: From DNA Discovery to Genome Complexity

Uncover the fascinating journey of molecular biology, tracing key milestones from the discovery of DNA to the intricate structure of genes and genomes. Dive into historical breakthroughs, such as understanding the role of genes in producing proteins, the double helix structure of DNA, and the comple

2 views • 30 slides


Place Value and Rounding Lesson for Year 5 Students

In this lesson on place value and rounding for Year 5 students, learners practice rounding numbers within 1,000,000. They are guided to round to the nearest 10, 100, 1,000, 10,000, and 100,000, and make decisions on rounding up or down. The lesson includes ranking UK cities by population size, estim

0 views • 23 slides


Explore Cromwell and WDL Bioinformatics Workflows

Discover the world of Cromwell and WDL bioinformatics workflows at any scale, with emphasis on the scalability and flexibility of the execution engine. Learn about the Workflow Description Language and basic plumbing concepts. Unveil the multiple backends for maximum flexibility in Cromwell's execut

0 views • 14 slides


Judicial Processes and Misconduct in New Zealand Disputes Tribunal

The New Zealand Disputes Tribunal, led by Principal Referee Anne Darroch, handles civil claims up to $15,000 or $20,000 by consent, with over 60 referees managing 16,000-20,000 claims yearly. Limited appeal rights are in place, with a complaints mechanism under process for all New Zealand Tribunals

0 views • 22 slides


Understanding Chromosomes: Key Components, Functions, and Significance

Chromosomes, essential in mitosis and meiosis, are condensed forms of DNA vital for heredity, mutation, and evolution. Learn about their structure, role in inheritance, and impact on species development through historical discoveries. Discover the importance of chromosome sets and genomes in gametic

0 views • 38 slides


Partnership Project Implementation Overview in CARICOM Region

An agreement between the Prime Minister of Japan and Heads of CARICOM Member States led to a project initiated in July 2014, aiming to benefit countries like Belize, Dominica, Grenada, Jamaica, and others. The project, managed by UNDP, involved multiple stakeholders and focused on various aspects su

0 views • 7 slides


Understanding Sequence Alignment in Next-Generation Sequencing Data

Sequence alignment plays a crucial role in analyzing Next-Generation Sequencing (NGS) data by identifying similarities between DNA, RNA, or protein sequences. Global and local alignment methods are used to arrange sequences and locate fragments derived from specific genes or transcripts. Challenges

0 views • 31 slides


Understanding Evolutionary Algorithms in Computer Science

Evolutionary algorithms, particularly genetic algorithms, simulate natural evolution to optimize parameters and discover new solutions. By creating genomes representing potential solutions and using genetic operators like mutation and crossover, these algorithms populate a search space, conduct loca

0 views • 33 slides


Analysis of Admixed Human Genomes: Methods and Challenges

Explore the methods and challenges involved in analyzing admixed human genomes, with a focus on the impact of gene flow on genetic diversity patterns. Learn about the underrepresentation of admixed populations in medical genetics and the goals of developing detailed quantitative models of human evol

0 views • 27 slides


Understanding Circularly Permuted Phage Genomes

Some phages have circularly permuted genomes where a linear concatamer of DNA is synthesized, filled into a phage head, and cut when full, ensuring continuous gene presence. This leads to no defined ends, no primer walks, and assembly into large contigs rather than distinct physical ends. This guide

0 views • 28 slides


Zillow Kaggle Competition Overview and Incentives

Zillow hosted a Kaggle competition with the objective of predicting log errors in their proprietary model. The competition involved feature engineering, unconventional methods, and a focus on neighborhood similarity. Scoring was based on Mean Absolute Error, with private scoring updates after the co

0 views • 47 slides


Enhancing Place Value Understanding in Year 5 Students

Explore activities and resources to develop students' understanding of place value up to 10,000, including reading, writing, ordering, and comparing numbers to at least 1,000,000. Engage in fluency exercises and reasoning and problem-solving tasks to reinforce learning. Discover how to read Roman nu

0 views • 80 slides


Guidelines for Purchases and Contracts at Office of State Engineer Facility Directors Conference

This document outlines the purchasing guidelines for the Office of State Engineer Facility Directors Conference, including the process for purchases under $10,000, purchases over $10,000 but under $100,000, and purchases exceeding the agency's basic authorization of $50,000. It details the requireme

0 views • 16 slides


Genomic Imputation Pipeline Overview

This document outlines a genomic imputation pipeline for multiple GWAS studies using reference panels such as 1000 Genomes Phase I data. It covers steps like data matching, phasing, and imputation using tools like Beagle and Minimac. The expected output includes imputed dosages and quality measures.

0 views • 6 slides


Genetics 210: Personalized Medicine and Genomics Course Overview

Genetics 210 is a course focused on personalized medicine and genomics designed for MDs, PhDs, and curious students. The course covers topics such as genotyping, informed consent, and exploring specific genetic loci. Students engage in projects like annotating genomes and debating FDA regulations. T

0 views • 24 slides


Importance of Functional Annotation of Animal Genomes in NIH Research

Functional Annotation of Animal Genomes (FAANG) is crucial for associating sequence variation with quantitative phenotypes in domestic animals, serving as important models for human health, disease, and ecology. The NIH actively participates in various genome projects involving cattle, horses, and c

0 views • 10 slides


Applications of Transgenic Animals in Biotechnology and Cloning

Cloning in animals offers the advantage of indefinite duplication of elite genotypes without the genetic risks of meiosis. Transgenic animals, genetically modified to carry foreign genes, play a crucial role in genetic research and the development of livestock with desired traits. Methods like DNA m

0 views • 13 slides


Decades of Marine RNA Virosphere Research

Research spanning over two decades has delved deep into the marine RNA virosphere, shedding light on the complex marine ecosystem and the characteristics of RNA viruses. Discoveries in deep marine virus taxonomy have led to significant taxonomic changes and advancements in virus classification and g

0 views • 10 slides


Mainstreaming Genomic Medicine: 100,000 Genomes Project Update

The Mainstreaming Genomic Medicine post provides insights into the background and progress of the 100,000 Genomes Project, including details on genetic vs. genomic testing, the setup of NHS Genomic Medicine Centres, types of cancer included, and samples taken. It covers the project's inception, key

0 views • 19 slides


Insights into NP-Hard Problems in Molecular Biology and Genetics

Understanding the complexity of NP-Hard Problems arising in molecular biology and genetics is crucial. These problems involve genome sequencing, global alignment of multiple genomes, identifying relations through genome comparison, discovering dysregulated pathways in human diseases, and finding spe

0 views • 24 slides


Basics of Genetics Engineering: Introduction to DNA and Gene Expression

Exploring the fundamentals of genetics engineering, this lecture covers topics such as DNA structure, gene expression, gene function, genome, mutation, recombination, and genetic modification. Understand the significance of DNA, genes, and the processes involved in gene expression. Dive into the wor

0 views • 20 slides


Gene Coding Potential Analysis for Multiple Genes

Analysis of coding potential for six genes revealed details such as start positions, gene lengths, coding potential scores, and functional predictions. Genes exhibit various characteristics like RBS values, Blast results, and Family of unknown function classifications based on multiple analyses like

0 views • 25 slides


Understanding Mutations and Natural Selection in Genomes

Explore how mutations impact survival and how genomes record these changes, distinguishing between functional and nonfunctional sequences. Learn about the effects of mutations on organism survival and the role of natural selection in shaping genetic variability.

0 views • 11 slides


Investigating Allelic Bias in Personal Genomes

This study delves into allelic bias in personal genomes, examining the influence of various factors such as sequencing datasets, removal of reads with allelic bias, and the impact on allele-specific single nucleotide variants (AS SNVs). The revised AlleleDB pipeline proposed includes steps for const

0 views • 6 slides


Understanding Human Genetic Variation and Its Implications

These slides explore the connection between genetic variations and phenotypes, focusing on how the human genome varies between individuals, identifying associations with phenotypes/diseases, and the impact of sequencing technologies on reading the genome. The evolution of projects like HapMap and th

0 views • 35 slides


Machine Learning Approach for Hierarchical Classification of Transposable Elements

This study presents a machine learning approach for the hierarchical classification of transposable elements (TEs) based on pre-annotated DNA sequences. The research includes data collection, feature extraction using k-mers, and classification approaches. Proper categorization of TEs is crucial for

0 views • 18 slides