Understanding Mixing Solutions for Chem/Pharm Students
Learn how to calculate the final strength of mixtures, mix different solutions effectively, and solve alligation problems in pharmacy and chemistry studies. Practice scenarios included with detailed solutions for better understanding.
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Mixing Solutions www.kent.ac.uk/student-learning-advisory-service
Mixing solutions Mixing solutions Introduction Calculating the final strength of a mixture of two or more different strength solutions Mixing different strength solutions to obtain a desired final strength and volume (alligation method) Bio/chem/Stage II pharm students
Mixing solutions Mixing solutions You add 60mL of a 10% w/v solution of sodium chloride to 100mL of a 20% w/v solution of drug A. What will the percentage strength be of the final solution? a). calculate amount of NaCl in each solution a). calculate amount of NaCl in each solution 20% 100?? = 20? 10% 60?? = 6? b). add amounts b). add amounts and volumes and volumes 6? 20? 100??= 26? 160?? 60??+ c). convert to c). convert to percentage percentage 26 160= 100 ? =2600 ? 160= 16.25% ?/?
Mixing solutions Mixing solutions You mix 150mL of a 1 in 25 (v/v) solution with 150mL of a 12% (v/v) solution. What is the % strength of the mixture? 1 25 150 = 6?? 12% 150?? = 18?? 6?? 150??+ 18?? 150??= 24?? 300??= 8% ?/?
Mixing solutions Mixing solutions You mix 75mL of a 1 in 5000 (v/v) solution with 45mL of a 0.2mcL/mL solution. What is the % strength of the mixture? 0.02% ?/? Answer:
Mixing solutions Mixing solutions alligation alligation Suppose you have stock of two different strength solutions. How would you mix them to create a specific quantity of an intermediate strength solution? desired % strength minus lower % strength higher % strength solution parts of higher % strength = desired % strength + higher % strength minus desired % strength lower % strength solution parts of lower % strength =
Mixing solutions Mixing solutions alligation alligation You require 200mL of a 30% solution. You have stock of 70% solution and 20% solution. How much of each should you use to create the required strength and quantity? 70 = 40mL of 70% solution 30 20 = 10 + reduce reduce 30 = 160mL of 20% solution 20 70 30 = 40 since since 1 1/ /5 5 of 200mL = 40mL of 200mL = 40mL
Mixing solutions Mixing solutions alligation alligation You require 120mL of a 15% solution. You have stock of 40% solution and 10% solution. How much of each should you use? Answer: 20?? ?? 40% ??? 100?? ?? 10%
Mixing solutions Mixing solutions Introduction Calculating the final strength of a mixture of two or more different strength solutions Mixing different strength solutions to obtain a desired final strength and volume (alligation method)
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