Understanding Heavy Menstrual Bleeding: A Comprehensive Overview

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A detailed exploration of heavy menstrual bleeding (HMB) by Consultant Gynaecologist Mary Connor, highlighting its impact on women's health and well-being. The importance of early investigations, treatments, and referrals, as well as key considerations for women with obesity or estrogen imbalances. Insights from NICE guidelines and the significance of a focused medical history in assessing HMB are also discussed.


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  1. Heavy menstrual bleeding An overview Mary Connor Consultant Gynaecologist Sheffield Teaching Hospitals NHS FT

  2. Disclosures Honoraria for teaching, travel expenses and consultancy fees received from: Medtronic Hologic Inc

  3. Learning outcomes 1. Know initial investigations when a woman first presents with HMB 2. Know initial treatments when a woman first presents with HMB 3. Know when referral to secondary care is indicated

  4. Why focus on HMB? Affects 1:5 women of reproductive age With 1:20 women contacting their GP each year Affects a woman s physical, psychological and social health and wellbeing 4% experience anxiety 67% suffer with depression

  5. Why focus on HMB? HMB in women with obesity or condition causing unopposed estrogen excess at risk of endometrial hyperplasia and cancer Rates of obesity, and therefore endometrial pathology, are rising

  6. NICE HMB 2018 Where to start

  7. NICE Quality Standards for HMB QS47

  8. Focused history nature of bleeding duration heaviness frequency regularity/irregularity of periods related symptoms pain tiredness

  9. Focused history impact on quality of life soiling of clothes or bedding quantity of sanitary protection at a time disruption to daily life (unable to go out, need to leave classroom) other factors that may affect treatment comorbidities previous treatment for HMB fertility requirements

  10. Focused history Establish symptoms that may indicate uterine cavity or histological abnormality, adenomyosis or fibroids intermenstrual bleeding postcoital bleeding pelvic pain pelvic pressure

  11. Investigations FBC test for coagulation disorders if HMB since menarche, personal/FH of coagulation disorders consider sexual health screening Cytology if due No indication for TFT, ferritin unless additional symptoms

  12. NICE HMB 2018 No further need to examine or investigate if no additional symptoms and low risk for endometrial pathology May offer treatment at this stage

  13. NICE HMB 2018 Pelvic ultrasound scan (preferably TVS) enlarged uterus on examination pelvic mass on examination pressure symptoms significant dysmenorrhoea unable to otherwise assess

  14. NICE Quality Standards for HMB QS47

  15. Role of cyclical progestogens Long course progestogens MPA (10 20 mg daily) or NET (5 mg tds) days 5 26/month reduced MBL, may be less effective than TXA, cocp, LNG-IUS No studies on satisfaction or QoL

  16. Summary - dose regimes Long cycle regimes definitely better than short cycle for reducing MBL, so ignore the BNF! Compliance seems better with continuous treatment than cyclical NET more effective than MPA at reducing MBL

  17. Summary - dose regimes LNG-IUS more effective at reducing overall blood loss than oral treatment IMB less troublesome with long cycles of oral progestogens than LNG-IUS

  18. Referral to Secondary Care 1. When Hysteroscopy indicated 2. Abnormal TVS or TAS endometria polyps submucosal fibroids <3cm 3. When pain a significant factor 4. Excessive bleeding 5. Severe anaemia

  19. NICE Quality Standards for HMB QS47

  20. NICE HMB 2018 Hysteroscopy for women at high risk of endometrial pathology persistent IMB persistent irregular bleeding infrequent bleeding and obese PCOS Lynch syndrome unsuccessful HMB treatment

  21. Referral to Secondary Care

  22. Learning outcomes 1. Know initial investigations when a woman first presents with HMB 2. Know initial treatments when a woman first presents with HMB 3. Know when referral to secondary care is indicated

  23. Sources of information

  24. Thank you! Any questions?

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