Insights into RNA Secondary Structure Prediction by Kieran Andrews

Slide Note
Embed
Share

Explore RNA secondary structure prediction methods and results, highlighting the role of tRNA and rRNA in cellular RNA composition. The process involves cycling through sequence folds, scoring based on base alignments, and identifying cis-regulatory elements. Results showcase paired bases in tRNA and transfer messenger RNA, with references for further exploration.

monter
monter Follow

Uploaded on Sep 27, 2024 | 0 Views

Download Presentation

Please find below an Image/Link to download the presentation.

The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author. Download presentation by click this link. If you encounter any issues during the download, it is possible that the publisher has removed the file from their server.

E N D

Presentation Transcript

  1. RNA Secondary Structure Prediction Kieran Andrews

  2. mRNA accounts for only between 1%-5% of cellular RNA. The rest of the cellular RNA is composed of RNA in its secondary structure, the majority being tRNA or rRNA. Data from RNA STRAND database from the BETA Lab of the University of British Columbia.

  3. High Level Steps UCAGACUUUUAAUCUGA Cycle through every possible fold of a sequence Score each sequence based on aligned complementary bases Scan for segments of the alignment without matches, performs the function on those segments Performs the function on segments extending over the aligned region U CAGACUUUAAUCUGA CU AGACUUUAAUCUGA UUUCAGACU | ||||| UUAAUCUGA

  4. Results tRNA (Molecule ID: PDB_00024) 12 paired bases My Results UUUCAGACU | | | | | | UUAAUCUGA 12 paired bases

  5. CUUUCGACAAAGAAAUUCUAUACCU (Molecule ID: RFA_00640) | | | | | | | | | | CAAGUGCCUUUCUGCAGUUUUUCAGGAGCGCAAGAUAGAUU 10 CUC | | GAC 2 C | GUGCC 1 AA | AUCU 1 UAGAACGCGAG | | | AGAUU 3 GC | | CGAG Cis-Regulatory Element

  6. Transfer Messenger RNA (Molecule ID: TMR_00007) 216 paired bases 4 pseudoknots My Results 180 paired bases

  7. Bibliography https://www.qiagen.com/kr/resources/faq?id=06a192c2-e72d-42e8-9b40-3171e1eb4cb8&lang=en http://www.rnasoft.ca/strand/show_results.php?molecule_ID=RFA_00640 http://www.rnasoft.ca/strand/show_results.php?molecule_ID=NDB_00051 http://www.rnasoft.ca/strand/show_results.php?molecule_ID=PDB_00024 http://www.rnasoft.ca/strand/show_results.php?molecule_ID=TMR_00007

Related


Address Prediction and Recovery in EECS 470 Lecture Winter 2024

Address Prediction and Recovery in EECS 470 Lecture Winter 2024

kenzie
Understanding H.264/AVC: Key Concepts and Features

Understanding H.264/AVC: Key Concepts and Features

leanna
Understanding Gene Translation: From RNA to Protein

Understanding Gene Translation: From RNA to Protein

torin
Understanding 10X Single Cell RNA-Seq Analysis

Understanding 10X Single Cell RNA-Seq Analysis

brandon
Privacy-Preserving Prediction and Learning in Machine Learning Research

Privacy-Preserving Prediction and Learning in Machine Learning Research

eviegrace
Exploring Nucleic Acids: DNA and RNA Structure and Function

Exploring Nucleic Acids: DNA and RNA Structure and Function

arianwen
Posttranscriptional Modification of RNA Overview

Posttranscriptional Modification of RNA Overview

colleen
RNA 3D Motif Analysis: Novel Sequence Variants Identification

RNA 3D Motif Analysis: Novel Sequence Variants Identification

mier158
Understanding Transcription and Translation in Protein Synthesis

Understanding Transcription and Translation in Protein Synthesis

shi_h
Understanding DNA Transcription and Translation in Biology

Understanding DNA Transcription and Translation in Biology

arno_y
Understanding Transcription in Biochemistry

Understanding Transcription in Biochemistry

fishback_a
Overview of RNA Transcription Process

Overview of RNA Transcription Process

elck556
Understanding Transcription and RNA Processing in Molecular Biology

Understanding Transcription and RNA Processing in Molecular Biology

cfar
Understanding RNA Polymerases and Transcription Process

Understanding RNA Polymerases and Transcription Process

neeko
Safety and Efficacy of RNA in Human Diet and Agricultural Crops

Safety and Efficacy of RNA in Human Diet and Agricultural Crops

bane_yer
Exploring RNA Secondary Structure Prediction in Bioinformatics

Exploring RNA Secondary Structure Prediction in Bioinformatics

malija
Understanding Nucleic Acids and RNA Molecules

Understanding Nucleic Acids and RNA Molecules

nou_dyk
Protein Secondary Structure Prediction: Insights and Methods

Protein Secondary Structure Prediction: Insights and Methods

sdaco
Understanding Nucleic Acids: DNA, RNA, and Nucleotides

Understanding Nucleic Acids: DNA, RNA, and Nucleotides

epigo
Decades of Marine RNA Virosphere Research

Decades of Marine RNA Virosphere Research

aror_nsa
Bulk RNA-seq Analysis: Basics and Downstream Insights

Bulk RNA-seq Analysis: Basics and Downstream Insights

dan_run
Role of RNA in Biological Processes and Protein Synthesis

Role of RNA in Biological Processes and Protein Synthesis

heffernan_w

More Related Content