Huntington's Disease Research Opportunities with Dr. Jamie Herron
Dr. Jamie Herron, a Consultant Psychiatrist specializing in Huntington's Disease, presents research opportunities including sub-investigator roles in clinical trials like Wave SNP3 and biomarker studies. The portfolio outlines the genetic basis of Huntington's, associated symptoms, and the chance to collaborate with experts in neurology and research nursing. Training and support are provided for interested researchers, offering a practical pathway to contribute to advancing knowledge of Huntington's Disease.
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Huntingtons disease research portfolio Dr Jamie Herron Consultant psychiatrist Huntington s disease psychiatry, QEUH, NHS GGC & Inpatient Old Age Psychiatry, Vale of Leven Hospital, NHS GGC
HD Introduction Sub-investigator opportunities: Wave SNP3 Enroll HD Clarity HD
12.3 per 100,000 Autosomal dominant CAG repeat extension mutation to the Huntingtin gene - >35 CAG repeats gives 100% disease penetrance Progressive motor abnormalities coordination, balance, chorea, dystonia, dysphagia Progressive cognitive decline and dementia Problematic neuropsychiatric symptoms depression, anxiety, OCD, irritability, affective dysregulation, psychosis Huntington s disease
Wave SNP3 Antisense oligonucleotide technology single strand complimentary to mRNA of mutant gene to modify expression Opportunities to be sub-investigator on a potentially transformative trial Collaborate with neurology, neuroanaesthetists and research nurses.
Biomarker trials - monitoring and assessment of the clinical course of HD and factors associated with progression. Training offered: UHDRS motor assessment PBA-S psychiatric assessment Columbia Suicide rating scale. Enroll HD and Clarity HD Sub-investigator roles Consenting Structured motor and psychiatric assessment. Supported by experienced research nurse team. Flexible to fit with your timetabled research sessions
Can inform special interest in neuropsychiatry Opportunity to develop working relationships with NHS GGC clinical researchers. Reasons to join the HD research team A straightforward way to fulfil research competencies structured training offered and flexible to your timetable can easily fit within your research sessions. Contact: james.herron3@nhs.scot or james.herron@ggc.scot.nhs.uk
