Emerging and Re-emerging Infectious Diseases

 
Introduction to emerging and re-emerging
infectious diseases
 
DOREEN SITALI
SCHOOL OF PUBLIC HEALTH
DEPT. OF HEALTH PROMOTION AND EDUCATION
 
Introduction
 
 
Global eradication of smallpox in 1977 and  discovery of antibiotics
led to optimism and complacency that infectious diseases as public
health problems could be eradicated or eliminated
Complacency  led to  fatal consequences;   infectious diseases are
leading cause of death globally today. About 17 million people die
from infectious diseases annually
 
Session objectives
 
Define key terms
Identify common  drivers of emerging and remerging infectious
diseases
Discuss the impact of EIs
Identify measures to mitigate EIs
 
What are emerging and re-emerging infectious diseases?
 
EIs
 - newly identified /unknown infections which cause public health problems
locally or globally
 
Term includes infections spreading to new geographic areas and those diseases that
were responding to antibiotics but are now resistant
 
 
Not always possible to know if these diseases are new in humans, or
whether were present but unrecognized throughout the years
 EIs thought to be due to a closer contact of man with their reservoirs
in nature, with a successful «jump» of the infectious agent from
animal to man across the species barrier
 
Examples of EIs
 
HIV infection which causes AIDS, with its sequelae of human suffering and economic
burden
Ebola hemorrhagic fever with a potential for international spread
Other examples of new or newly detected infectious diseases of global concern include a
new form of cholera
hepatitis C and hepatitis E
Legionnaires’ disease, and Lyme disease, 
dengue fever, West Nile virus, and the Zika
virus.
COVID
 
Re-emerging infectious diseases
 
infections that have appeared after significant decline in their incidence
often reappear in epidemic proportions.
Tuberculosis  increasing worldwide due in part to its close association with HIV
infection
cholera  re-introduced into countries and continents where it had previously
disappeared, and where it can spread because water and sanitation systems have
deteriorated
dengue or «breakbone» fever has started to occur in urban areas where mosquito
control has broken down.
 
Reemerging diseases include
M
alaria, Tuberculosis, Cholera, Pertussis, Influenza, Pneumococcal disease, and
gonorrhea.
Ebola , Marburg
Crimean congo haemorrhagic fever
Lassa fever
MERS, SARS
Nipah, Rift valley fever
Covid
 
Why are  these diseases emerging?
 
Emergence is multifactorial in origin:
Rapid population growth – uncontrolled urbanization- crowded cities- unhygienic
conditions that provide breeding ground for pathogens
intense international travel and growing trade and tourism
Migration and displacement of people due to war, strife or disasters
Agricultural practices
 
changes in handling and processing of large quantities of food;
and increased exposure of humans to disease vectors and reservoirs in nature.
Mutations that lead to new strains; and drug resistance; 
Resistance of vectors to
pesticides
Most significant factor:  deteriorating public health infrastructure which is
unable to cope with population demands, and the emergence of resistance to
antibiotics linked to their increased misuse.
 
Bioterrorism
 
Possible deliberate release of infectious agents by dissident individuals or
terrorist groups
 Biological agents are attractive instruments of terror‐ easy to produce,
mass casualties, difficult to detect, ‐ B. anthracis, C. botulinum toxin, F.
tularensis, Y. pestis, Variola virus, Viral haemorrhagic fever viruses
 Likeliest route‐ aerosol dissemination
 
During first half of the 20th century deaths from infectious diseases declined
because of improved hygiene and nutrition. This trend was strengthened with the
advent of vaccines and antibiotics during the 1940s and culminated in the late
1970s in the eradication of one infectious disease, smallpox. Because at that time
infectious diseases appeared to be a decreasing threat, funds for their control
were channeled to other problems, experts on infectious disease retired or left
the field and students turned to more rewarding subjects than viruses and
bacteria - the infrastructure for communicable disease control began to crumble.
 
 
 
 
Emerging and re-emerging infections reflect the constant struggle of
microorganisms to survive.
 
Transmission of Infectious Agent from Animals to
Humans‐ ZOONOTIC diseases
 
>2/3rd emerging infections originate from animals‐ wild & domestic e.g
Emerging Influenza infections in Humans associated with Geese, Chickens & Pigs
Animal displacement in search of food after deforestation/ climate change (Lassa
fever)
 Humans themselves penetrate/ modify unpopulated regions‐ come closer to
animal reservoirs/ vectors (Yellow fever, Malaria)
 
Impact of EIs
 
Economic
Social
Public health
 
PRIORITY AREAS FOR ACTION
 
1. 
STRENGHTHENING NATIONAL CAPACITIES
Create early warning systems and rapid response mechanisms
Strengthen epidemiological laboratory and systems
Early action for prevention and control
 
 
 
2. 
Intersectoral collaboration
 
Constant dialogue about the health implications of projects in other
ministries
Close collaboration between health and other ministries
 
Intercountry collaboration
 
Rapid flow of disease surveillance between countries
 
The global response
 
Since 1992 alarm over emerging and re-emerging diseases  resulted in a number
of national and international initiatives to restore and improve surveillance and
control of communicable diseases.  Member States of WHO expressed their
concern in a resolution of the World Health Assembly in 1995, urging all Member
States to strengthen surveillance for infectious diseases in order to promptly
detect re-emerging diseases and identify new infectious diseases. The WHA
recognized that the success of this resolution depends on  ability to obtain
information on infectious diseases and  willingness to communicate  information
nationally and internationally.
 
The World Health Organization warned in its 2007 report that
infectious diseases are emerging at a rate that has not been seen
before. Since the 1970s, about 40 infectious diseases have been
discovered, including SARS, Ebola, Avian flu, and Swine flu
 
Surveillance and Response 
Global Outbreak Alert & Response Network Coordinated by WHO  Mechanism
for combating international disease outbreaks
 Ensure rapid deployment of technical assistance, contribute to long‐term
epidemic preparedness & capacity building
Applied Research 
Infrastructure and Training 
Prevention and Control
 
Conclusion
 
Infectious diseases will continue to dominated disease scenarios in
most countries.
The most sustainable way to deal with them is through early detection
and rapid response.
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Emerging and re-emerging infectious diseases pose significant challenges to global public health, with factors such as increased human-animal contact and microbial resistance contributing to their spread. This presentation explores the definitions, examples, and impacts of these diseases, emphasizing the need for heightened awareness and proactive measures to mitigate their effects.

  • Emerging diseases
  • Re-emerging diseases
  • Public health
  • Global health
  • Disease prevention

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  1. Introduction to emerging and re-emerging infectious diseases DOREEN SITALI SCHOOL OF PUBLIC HEALTH DEPT. OF HEALTH PROMOTION AND EDUCATION

  2. Introduction Global eradication of smallpox in 1977 and discovery of antibiotics led to optimism and complacency that infectious diseases as public health problems could be eradicated or eliminated Complacency led to fatal consequences; infectious diseases are leading cause of death globally today. About 17 million people die from infectious diseases annually

  3. Session objectives Define key terms Identify common drivers of emerging and remerging infectious diseases Discuss the impact of EIs Identify measures to mitigate EIs

  4. What are emerging and re-emerging infectious diseases? EIs - newly identified /unknown infections which cause public health problems locally or globally Term includes infections spreading to new geographic areas and those diseases that were responding to antibiotics but are now resistant

  5. Not always possible to know if these diseases are new in humans, or whether were present but unrecognized throughout the years EIs thought to be due to a closer contact of man with their reservoirs in nature, with a successful jump of the infectious agent from animal to man across the species barrier

  6. Examples of EIs HIV infection which causes AIDS, with its sequelae of human suffering and economic burden Ebola hemorrhagic fever with a potential for international spread Other examples of new or newly detected infectious diseases of global concern include a new form of cholera hepatitis C and hepatitis E Legionnaires disease, and Lyme disease, dengue fever, West Nile virus, and the Zika virus. COVID

  7. Re-emerging infectious diseases infections that have appeared after significant decline in their incidence often reappear in epidemic proportions. Tuberculosis increasing worldwide due in part to its close association with HIV infection cholera re-introduced into countries and continents where it had previously disappeared, and where it can spread because water and sanitation systems have deteriorated dengue or breakbone fever has started to occur in urban areas where mosquito control has broken down.

  8. Reemerging diseases include Malaria, Tuberculosis, Cholera, Pertussis, Influenza, Pneumococcal disease, and gonorrhea. Ebola , Marburg Crimean congo haemorrhagic fever Lassa fever MERS, SARS Nipah, Rift valley fever Covid

  9. Why are these diseases emerging? Emergence is multifactorial in origin: Rapid population growth uncontrolled urbanization- crowded cities- unhygienic conditions that provide breeding ground for pathogens intense international travel and growing trade and tourism Migration and displacement of people due to war, strife or disasters Agricultural practices

  10. changes in handling and processing of large quantities of food; and increased exposure of humans to disease vectors and reservoirs in nature. Mutations that lead to new strains; and drug resistance; Resistance of vectors to pesticides Most significant factor: deteriorating public health infrastructure which is unable to cope with population demands, and the emergence of resistance to antibiotics linked to their increased misuse.

  11. Bioterrorism Possible deliberate release of infectious agents by dissident individuals or terrorist groups Biological agents are attractive instruments of terror easy to produce, mass casualties, difficult to detect, B. anthracis, C. botulinum toxin, F. tularensis, Y. pestis, Variola virus, Viral haemorrhagic fever viruses Likeliest route aerosol dissemination

  12. During first half of the 20th century deaths from infectious diseases declined because of improved hygiene and nutrition. This trend was strengthened with the advent of vaccines and antibiotics during the 1940s and culminated in the late 1970s in the eradication of one infectious disease, smallpox. Because at that time infectious diseases appeared to be a decreasing threat, funds for their control were channeled to other problems, experts on infectious disease retired or left the field and students turned to more rewarding subjects than viruses and bacteria - the infrastructure for communicable disease control began to crumble.

  13. Emerging and re-emerging infections reflect the constant struggle of microorganisms to survive.

  14. Transmission of Infectious Agent from Animals to Humans ZOONOTIC diseases >2/3rd emerging infections originate from animals wild & domestic e.g Emerging Influenza infections in Humans associated with Geese, Chickens & Pigs Animal displacement in search of food after deforestation/ climate change (Lassa fever) Humans themselves penetrate/ modify unpopulated regions come closer to animal reservoirs/ vectors (Yellow fever, Malaria)

  15. Impact of EIs Economic Social Public health

  16. PRIORITY AREAS FOR ACTION 1. STRENGHTHENING NATIONAL CAPACITIES Create early warning systems and rapid response mechanisms Strengthen epidemiological laboratory and systems Early action for prevention and control

  17. 2. Intersectoral collaboration Constant dialogue about the health implications of projects in other ministries Close collaboration between health and other ministries

  18. Intercountry collaboration Rapid flow of disease surveillance between countries

  19. The global response Since 1992 alarm over emerging and re-emerging diseases resulted in a number of national and international initiatives to restore and improve surveillance and control of communicable diseases. Member States of WHO expressed their concern in a resolution of the World Health Assembly in 1995, urging all Member States to strengthen surveillance for infectious diseases in order to promptly detect re-emerging diseases and identify new infectious diseases. The WHA recognized that the success of this resolution depends on ability to obtain information on infectious diseases and willingness to communicate information nationally and internationally.

  20. The World Health Organization warned in its 2007 report that infectious diseases are emerging at a rate that has not been seen before. Since the 1970s, about 40 infectious diseases have been discovered, including SARS, Ebola, Avian flu, and Swine flu

  21. Surveillance and Response Global Outbreak Alert & Response Network Coordinated by WHO Mechanism for combating international disease outbreaks Ensure rapid deployment of technical assistance, contribute to long term epidemic preparedness & capacity building Applied Research Infrastructure and Training Prevention and Control

  22. Conclusion Infectious diseases will continue to dominated disease scenarios in most countries. The most sustainable way to deal with them is through early detection and rapid response.

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