Advanced Imaging Techniques for Plaque Risk Assessment

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Cutting-edge imaging methods, such as combining light and ultrasound in photoacoustic imaging, trained neural networks for classification and risk assessment, and ultrasound for tissue composition analysis are key aspects discussed in the Innovation Workshop related to CVENT and H2020 project on February 3, 2017, Brussels. The focus is on risk assessment of plaque rupture, classification, and tissue composition of the plaque, utilizing innovative technologies for improved diagnosis and treatment decisions.


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  1. Innovation Workshop ICT 731771 CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  2. Ultrasound imaging Innovation 1960 2017 Need for 1) Functional information 2) Combination of light and ultrasound in photoacoustic imaging (PAI) 3) Trained neural networks for Classification, Segmentation and risk assessment CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  3. Our challenge Risk assessment of plaque rupture Classification Tissue composition of the plaque Risk assessment Plaque Composition ? Risk ? Blood vessel CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  4. Our challenge Combination of light and Ultrasound Ultrasound imaging with integrated intelligence Photoacoustic imaging for tissue composition Integrated trained neural networks for classification and risk assessment CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  5. Photoacoustic imaging principle pulsed light in ultrasound out temperature increase stress Ultrasound detection relaxation Light absorption CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  6. Photoacoustic imaging principle Absorption contrast light Penetration depth and resolution of ultrasound www.luminetx.com VeinViewer The best of sound and multi-wavelength light CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  7. Why PAI Ultrasound Cost effective point-of-care imaging High spatial and temporal resolution o Lack of functional information Morphological imaging CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  8. Why PAI Photoacustics Optical contrast at ultrasound resolution Tissue characterization and differentiation http://www.ireap.umd.edu/materials/facilities/laser.JPG Functional imaging Spectroscopic imaging Combined (multi-modality) imaging o High risk long-term process with great spin-off and opportunities CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  9. Handheld Photoacoustic probe CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  10. Handheld Photoacoustic probe Multi wavelength PA/US probe 1.4 mJ/pulse (808, 915, 940, 980 nm) Probe position awareness system Multi-wavelength Diode laser Micro optics Passive cooling Laser driver Ultrasound transducer CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  11. Ultrasound imaging Early disease detection Treatment monitoring Functional Information o Point of care Portable Affordable o Trained neural networks for Classification Segmentation Risk assessment CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  12. US blood vessel training set 300,000 US images with boxes CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  13. Cooperation Cooperation is a key factor for success Best practice Direct communication. Questions and open discussion. Isolate, understand and solve problems. Exchange of students and project members. Regular meetings. CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  14. Innovation Workshop ICT 731771 CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  15. CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  16. US system innovations Multi channel ADC convertors. High bandwidth data transfer. System on chip (SoC) solutions. Fully software based systems. System on Chip (Soc) CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  17. CVENT PAI research system In use for: 1) Validation and verification of the CVENT PA/US probe. 2) CVENT signal processing prototyping (off-line and real-time processing). 3) Small clinical studies (in-vitro and in-vivo). CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  18. Objectives Risk assessment of plaque rupture Four main objectives: o Photoacoustic imaging (PAI) probe. o PAI system engineering. o Advanced PAI signal processing. o PAI system verification and validation. CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  19. Work packages CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

  20. Starting point Multi wavelength PA/US probe 1.4 mJ/pulse (808, 915, 940, 980 nm) CVENT, H2020 project 731771, Innovation Workshop February 3, 2017 Brussels

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