Enhancing Stroke Treatment Response Through Advanced Imaging Management Center Strategy

This information details the strategy proposed by the Imaging Management Center to improve stroke treatment response. It emphasizes the importance of timely uploading of brain imaging data within specified timeframes using the AMBRA platform. The process involves modalities like NCCT, CTA, MRI, and MRA for central review. Individual site training is provided to ensure successful image uploading and compliance with institutional policies. Emphasis is placed on seamless workflow for effective imaging studies in the trial.

• Stroke Treatment
• Imaging Management
• Brain Imaging
• AMBRA Platform
• Site Training

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Uploaded on Aug 30, 2024 | 0 Views

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1. Imaging Management Center Information Strategy for Improving Stroke Treatment Response

2. Achala Vagal, MD, MS Vivek Khandwala, Ph.D Holly Wilcox, MS Imaging CRP, NIH StrokeNet Imaging Management Center (Primary point of contact for the sites) NIH StrokeNet Imaging Management Center Team PI, NIH StrokeNet Imaging Management Center Research Manager, NIH StrokeNet Imaging Management Center

3. Imaging Modalities All brain parenchymal, vascular, and perfusion imaging modalities collected within the first 30 (+/-4) hours from drug administration should be uploaded in the central imaging database- AMBRA- within 7 days of hospitalization Imaging modalities for baseline and 30 (+/- 4) hours from drug administration o NCCT / CTA / CTP o MRI / MRA / MRP Choice of brain parenchymal imaging modality (i.e., CT vs MRI) for baseline is based on what is routinely performed as standard of care at your institution, however, for follow up imaging, NCCT is required. Imaging variables will be ascertained centrally. The central readers will be blinded to the patient s clinical data.

4. Imaging- How to Upload Imaging will be electronically transferred from your site to the Imaging Management Center for central review using cloud based AMBRA platform. Imaging Management Center will be working with each of the sites individually and walk them through uploading the imaging data into AMBRA platform.

5. Imaging Training Once site is activated, Holly Wilcox (Imaging CRP) from our team will contact you to schedule individual site training The following study personnel need to attend site imaging trainings: Study coordinator(s) Any other personnel that will be involved in sending images

6. Imaging Training Contd During individual site training sessions, the following topics will be covered: Navigating through the internal processes of acquiring imaging data Instructions on accessing and uploading images into AMBRA AMBRA accounts will be created prior to the training Practice uploading images to AMBRA Imaging Queries Each site is different. Our main focus is to walk through your site s institutional policies and processes and to determine the best workflow that allows for timely and successful upload of imaging studies for the trial.