The OCTIVUS Randomized Clinical Trial compared the clinical efficacy and safety of Optical Coherence Tomography (OCT)-guided and Intravascular Ultrasound (IVUS)-guided strategies in patients undergoing PCI for significant CAD. The study aimed to determine if OCT-guided PCI is noninferior to IVUS-gui

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This prospective, multicentre, randomised clinical trial led by Dr. Tiffany Patterson aims to determine whether direct delivery to a cardiac arrest centre following non-ST elevation out-of-hospital cardiac arrest reduces deaths compared to delivery to the nearest emergency department. Funded by the

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Cardiovascular disease is a growing concern in individuals living with HIV, despite advancements in treatment. The REPRIEVE Trial sheds light on the importance of assessing cardiovascular risk and implementing primary prevention measures in this population. Dr. Grinspoon's financial disclosures and

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The REPRIEVE trial focuses on developing a cardiovascular disease prevention strategy for individuals living with HIV. It addresses the increased risk of CVD in this population, even with good viral suppression. The study evaluates the use of pitavastatin, a statin with anti-inflammatory properties,

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This UK-wide clinical trial aims to assess the effectiveness of early peripheral norepinephrine infusion in adult patients with septic shock. The study will compare the impact on mortality and other outcomes of targeting a mean arterial pressure (MAP) above 65mmHg within the first 48 hours of admiss

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The PUSH-AHF trial, conducted at the University Medical Center Groningen, aimed to evaluate the effectiveness and safety of natriuresis-guided diuretic therapy in acute heart failure. The study design was pragmatic, prospective, single-center, open-label, randomized, and controlled. Key outcomes inc

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Empagliflozin's impact on cardiovascular and renal events in heart failure with reduced ejection fraction was assessed in the EMPEROR-Reduced trial led by Milton Packer, MD, and Faiez Zannad, MD. The trial, enriched for patients with severe left ventricular dysfunction, randomized participants to em

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This module provides detailed information on the follow-up process in the STRATA trial for adults with autism and anxiety. It covers the timeline for sending questionnaires at 16, 24, and 52 weeks post-randomization, methods of completion, responsibilities of local research staff, and incentives for

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Explore the process of simulating clinical trial designs, including traditional and adaptive approaches. Learn how to generate data, conduct analysis, make within-trial decisions, and summarize results using fixed-sample two-arm parallel group trials and group-sequential designs. Dive into methods l

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The UK Mini Mitral Trial compares the outcomes of minimally invasive thoracoscopic-guided right minithoracotomy versus conventional sternotomy for mitral valve repair. The trial aims to determine if physical function improvement post-surgery at 12 weeks is superior in the minimally invasive approach

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In this informational document presented by Shawn M. Smith of Cleveland Doan LLP Strata Lawyers, you will learn about the different types of strata plans, including conventional and bare land plans, as well as the concept of common property and limited common property in strata developments. The doc

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The Human Rights Code aims to prevent discrimination, promote equality, and provide redress for those discriminated against. It prevails over other legislation, including the Strata Property Act. Strata corporations are subject to various provisions of the Code, impacting areas such as publications,

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Explore the various types of hearings available in the Court Management System, such as Motion Calendar, Special Sets, Calendar Call/Trial, Pre-Trial Conference, and Case Management. Learn how to set up new hearings/events and understand the process of generating trial orders and pre-trial conferenc

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The STRESS-L Trial focuses on reversing septic shock using Landiolol, a beta-blockade treatment. It provides training for non-GCP trained clinicians involved in eligibility review, medical care, and prescribing in the trial. The slides cover key GCP principles, trial agenda, study information, backg

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The CLEAR Trial is a 2x2 factorial randomized trial evaluating the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the trial focuses on clinical and c

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ACST-2 is a randomized trial comparing carotid artery stenting (CAS) versus carotid artery surgery (CEA) in asymptomatic patients with severe carotid stenosis. The trial, published in The Lancet in August 2021, involved 3625 patients. While surgery has been shown to reduce stroke rates, modern medic

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The Sixth Amendment guarantees various rights during criminal trials, such as a speedy and public trial, trial by jury, notice of accusations, the right to confront witnesses, and the assistance of counsel. Defendants can opt for a bench trial where the judge decides innocence or guilt. Juries, typi

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The Antler Orogeny, a Late Devonian to mid-Early Mississippian event, impacted the passive margin of the North American continent, particularly in Nevada and Idaho. The orogeny involved displacement of oceanic strata, subsidence of a foreland basin, and maintenance of highlands in the interior regio

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The CLEAR Trial is a 2x2 factorial randomized trial examining the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the study focuses on exacerbation ma

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NCI-MATCH is a groundbreaking clinical trial aiming to match tumor gene alterations with targeted therapies. The interim analysis results revealed impressive patient enrollment and site participation exceeding expectations. Despite challenges with pausing new patient registrations for the analysis,

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Understanding the key components of a clinical trial research protocol is essential for conducting successful studies. This includes identifying session objectives, discussing trial protocol contents, exploring observational study elements, and learning about reporting guidelines. Study objectives f

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Enhance your trial skills in family law with a focus on evidence collection, trial strategies, and client examination. Learn best practices for preserving evidence, drafting persuasive statements, and navigating trials confidently. This workshop covers important aspects of evidence collection, such

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Explore the innovative tool nQuery Predict for accurate clinical trial milestone predictions, demonstrated in a webinar hosted by industry experts. Learn about key milestones, adaptive design considerations, enrollment predictions, and the significance of statistical approaches in optimizing trial d

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Exploring the detailed process of civil rights litigation, covering steps from fact gathering to trial preparation and post-trial activities. The visual presentation showcases key elements such as client retention, complaint filing, discovery phases, trial preparation, and post-trial procedures like

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Simulation competition where students portray attorneys and witnesses in a civil jury trial based on the case of professional writer Riley Winter suing an online magazine for wrongful termination due to age discrimination. Judges preside over the trial, score performances, and provide feedback, focu

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Short term rentals like Airbnb pose challenges for strata corporations, impacting turnover, security, and community cohesion. Companies such as High Street Accommodations offer furnished units for extended stays. Regulations in Vancouver restrict the use of dwelling units for periods less than a mon

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In this competition, students simulate a criminal jury trial where they take on roles as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves State v. Sinclair, focusing on the murder trial of Skyler Sinclair, a suspect in the death of an undercover officer

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Civil Resolution Tribunal (CRT) is introduced as a place to resolve strata-related disputes in an accessible, speedy, and economical manner. It aims to encourage agreement between parties or decide claims. CRT's mandate includes providing fair dispute resolution services using electronic tools. The

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AIRWAYS-3 is a multi-centre, open-label, randomized trial evaluating the clinical and cost effectiveness of a supraglottic airway (SGA) versus tracheal intubation during in-hospital cardiac arrest (IHCA). The trial aims to determine the functional status and health-related quality of life outcomes o

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Explore the challenges and solutions related to smoking in strata corporations, including the need for smoking bans, the role of council, provincial legislation impacting smoking, and strategies for managing smoking complaints. Learn how to address smoke allergies, smoking addictions, and the risks

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Exploring the roles and responsibilities of property managers and strata councils in enforcing nuisance and noise bylaws, this presentation delves into the challenges faced, pre-enforcement strategies, case studies, and information to provide to councils for effective resolution of disputes between

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The CLEAR Trial is a 2x2 factorial randomized trial led by Professor Stuart Elborn and Professor Judy Bradley to assess the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves various study sites and potential new sit

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Understanding the role and benefits of partnering with a Clinical Trial Unit (CTU) is essential for potential Chief Investigators. A CTU handles various aspects of trial coordination, from developing trial materials to overseeing regulatory permissions and data management. UK Clinical Trials Units (

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The trial of O.J. Simpson for the brutal murders of Nicole Brown Simpson and Ron Goldman captivated the nation, with overwhelming evidence implicating Simpson. Despite the compelling case against him, Simpson's defense team, led by Johnnie Cochran, raised doubts about the integrity of the evidence a

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Participants are preparing for the trial of King Louis XVI by researching charges, roles, and responsibilities. The trial process includes reading indictments, opening statements, questioning phases, and final statements. Each role, including Louis, Marie, Robespierre, Marat, and a woman from the 3r

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Simulation of a criminal jury trial where students act as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves the attempted murder of Kerry Bell-Leon, with witness selection varying in each round. Judges play crucial roles in presiding over the trial, scor

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This module provides an overview of the STRATA Carer Study, which aims to explore how treating anxiety in adults with autism influences the burden on their carers. The nested study runs parallel to the main STRATA trial and involves assessing carer burden over a 52-week treatment period with sertral

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The CLEAR Trial, led by Professor Stuart Elborn and Professor Judy Bradley, aims to assess the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves a 2x2 factorial design and various study sites acros

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The CLEAR Trial is a 2x2 factorial randomized trial assessing the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley, the trial involves randomization, sealed

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The presentation discusses the obligations of strata corporations under the Personal Information Protection Act (PIPA), focusing on privacy guidelines, objectives of PIPA, definition of personal information, and rights of owners and tenants regarding their personal information. It also outlines the

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