OCTIVUS Randomized Clinical Trial: OCT-Guided vs IVUS-Guided PCI
The OCTIVUS Randomized Clinical Trial compared the clinical efficacy and safety of Optical Coherence Tomography (OCT)-guided and Intravascular Ultrasound (IVUS)-guided strategies in patients undergoing PCI for significant CAD. The study aimed to determine if OCT-guided PCI is noninferior to IVUS-gui
7 views • 27 slides
ARREST Trial: Expedited Transfer for Non-ST Elevation OHCA
This prospective, multicentre, randomised clinical trial led by Dr. Tiffany Patterson aims to determine whether direct delivery to a cardiac arrest centre following non-ST elevation out-of-hospital cardiac arrest reduces deaths compared to delivery to the nearest emergency department. Funded by the
0 views • 17 slides
Comprehensive Guide to Salary Negotiation and Communication in the Workplace
This comprehensive guide provides valuable information, group exercises, and discussion questions to help managers and employees better understand salary negotiation and prepare for upcoming discussions. Covering fundamental principles from central agreements, guidelines for fair negotiations, salar
2 views • 18 slides
Insights from the REPRIEVE Trial for Managing Cardiovascular Risk in Patients with HIV
Cardiovascular disease is a growing concern in individuals living with HIV, despite advancements in treatment. The REPRIEVE Trial sheds light on the importance of assessing cardiovascular risk and implementing primary prevention measures in this population. Dr. Grinspoon's financial disclosures and
0 views • 35 slides
The REPRIEVE Trial: Developing Cardiovascular Disease Prevention Strategy for People Living with HIV
The REPRIEVE trial focuses on developing a cardiovascular disease prevention strategy for individuals living with HIV. It addresses the increased risk of CVD in this population, even with good viral suppression. The study evaluates the use of pitavastatin, a statin with anti-inflammatory properties,
1 views • 33 slides
Early Vasopressors in Sepsis Clinical Trial: Improving Patient Outcomes
This UK-wide clinical trial aims to assess the effectiveness of early peripheral norepinephrine infusion in adult patients with septic shock. The study will compare the impact on mortality and other outcomes of targeting a mean arterial pressure (MAP) above 65mmHg within the first 48 hours of admiss
1 views • 9 slides
Pragmatic Urinary Sodium-Based Treatment Algorithm in Acute Heart Failure (PUSH-AHF) Trial Overview
The PUSH-AHF trial, conducted at the University Medical Center Groningen, aimed to evaluate the effectiveness and safety of natriuresis-guided diuretic therapy in acute heart failure. The study design was pragmatic, prospective, single-center, open-label, randomized, and controlled. Key outcomes inc
2 views • 20 slides
CLEAR Outcomes Trial: Bempedoic Acid for Cardiovascular Prevention
The CLEAR Outcomes Trial investigated the effects of bempedoic acid, an ATP citrate lyase inhibitor, on cardiovascular outcomes in primary prevention patients. Results showed a reduction in cardiovascular events with bempedoic acid, particularly in patients intolerant to statins. Baseline characteri
0 views • 13 slides
Double-blind, Randomized Trial of Interatrial Shunt in HF Patients
This study details the principal results of the RELIEVE-HF trial, investigating the safety and effectiveness of the V-Wave Ventura interatrial shunt device in patients with heart failure with reduced and preserved ejection fraction. Key inclusion and exclusion criteria are outlined, emphasizing the
0 views • 30 slides
Effective Trial Presentation Tips and Best Practices by Judge Renee A. Goble
Enhance your trial presentation skills with insights from Judge Renee A. Goble of Denver County Court. Learn about trial structure, direct and cross-examination techniques, understanding evidence, objections, and more to improve your courtroom performance.
0 views • 18 slides
Negotiation Phase Strategies for Successful Contract Signatures
This training course provides an insightful overview of the negotiation phase post-ESA approval in the context of PECS Call for Proposals. It aims to guide entities on navigating the negotiation process effectively to achieve successful contract signings. The content covers key steps, responsibiliti
1 views • 34 slides
Professional Conflict Resolution and Mediation Expert
Mediation is a conflict resolution process where a mediator assists parties in constructive discussions to develop a mutually acceptable resolution. As a Mediation and Negotiation Specialist, Michael Gregory aids organizations in overcoming conflicts, whether business-to-business, business-to-govern
1 views • 5 slides
Effective Strategies for Negotiation Success in ESA Proposals
Learn how to navigate the negotiation phase effectively in ESA proposals to maximize benefits and secure successful outcomes. This guide covers key steps, responsibilities, and ways to avoid common pitfalls during the negotiation process. Get insights on handling negotiation points, recording discus
0 views • 34 slides
Mastering Negotiation Skills in the Workplace
Develop your negotiation skills to effectively resolve conflicts, make beneficial compromises, and build strong relationships in the workplace. Learn the definition, benefits, examples, and types of negotiation skills to navigate various scenarios successfully.
0 views • 26 slides
Understanding Plea Bargaining in Criminal Procedure Code, 1973
Plea bargaining, a pre-trial negotiation process where the accused pleads guilty for certain concessions, has a historical background and aims to reduce trial delays and ensure just punishment. Introduced in 2005, Chapter 21A of the Cr.P.C. outlines the concept. It applies to offenses with punishmen
1 views • 21 slides
Understanding the Definition of Hearsay in Virginia Courts by Gerald I. Fisher, Senior Judge
Preliminary principles and rules regarding hearsay in Virginia courts, including the effective date of the Virginia Rules of Evidence, application of rules in various trial scenarios, criteria for admissibility of evidence by trial judges, and reasons for the legal distrust of hearsay evidence. The
1 views • 78 slides
Mastering Negotiation Dynamics: Key Concepts and Strategies
Explore the intricacies of negotiation dynamics, from advocacy surveys to win-win strategies, and understand essential concepts like preparation, barriers to resolution, and the bargaining zone. Uncover the 5 rules of negotiation success and learn how to prioritize negotiable items effectively for s
1 views • 19 slides
Empagliflozin Effects on Heart Failure with Reduced Ejection Fraction: EMPEROR-Reduced Trial Overview
Empagliflozin's impact on cardiovascular and renal events in heart failure with reduced ejection fraction was assessed in the EMPEROR-Reduced trial led by Milton Packer, MD, and Faiez Zannad, MD. The trial, enriched for patients with severe left ventricular dysfunction, randomized participants to em
1 views • 22 slides
Understanding Plea Bargaining: Definition, Applicability, and Process
Plea bargaining is a negotiation process between the prosecution and defense, allowing the accused to plead guilty for reduced punishment. It aims to expedite case disposal and lessen court burden. Applicability criteria include offenses with a maximum 7-year sentence, involving women or children un
0 views • 14 slides
Comparison of FFR-guided PCI vs Angiography-guided PCI in AMI with Multivessel Disease: FRAME-AMI Trial
In patients with acute myocardial infarction (AMI) and multivessel coronary artery disease, this study aims to compare fractional flow reserve (FFR)-guided PCI with angiography-guided PCI for non-infarct-related artery lesions. The hypothesis is that selective PCI guided by FFR is superior to routin
2 views • 23 slides
Principles of Effective Negotiation Workshop
Explore the art of negotiation through a strategic framework, relationship management, and participatory role-plays. Understand the process of negotiation, its value, and learn practical tactics to enhance your negotiation skills. Embrace self-awareness, active listening, and preparation to achieve
0 views • 13 slides
Simulation Techniques in Clinical Trial Design
Explore the process of simulating clinical trial designs, including traditional and adaptive approaches. Learn how to generate data, conduct analysis, make within-trial decisions, and summarize results using fixed-sample two-arm parallel group trials and group-sequential designs. Dive into methods l
1 views • 23 slides
UK Mini Mitral Trial: Minimally Invasive Thoracoscopic Approach vs Conventional Sternotomy for Mitral Valve Repair
The UK Mini Mitral Trial compares the outcomes of minimally invasive thoracoscopic-guided right minithoracotomy versus conventional sternotomy for mitral valve repair. The trial aims to determine if physical function improvement post-surgery at 12 weeks is superior in the minimally invasive approach
1 views • 24 slides
Understanding Pretrial Motions in Limine in Civil Pretrial Practice
Pretrial motions in limine (MIL) play a crucial role in civil pretrial practice by seeking evidentiary rulings in advance to control the introduction of evidence at trial. These motions aim to prevent the admission of irrelevant, inadmissible, or prejudicial evidence and can also facilitate the intr
1 views • 17 slides
Understanding Different Types of Hearings in the Court Management System
Explore the various types of hearings available in the Court Management System, such as Motion Calendar, Special Sets, Calendar Call/Trial, Pre-Trial Conference, and Case Management. Learn how to set up new hearings/events and understand the process of generating trial orders and pre-trial conferenc
0 views • 18 slides
Enhancing Negotiation Skills for University Administrators in a Changing World
University administrators must acquire critical negotiation skills to adapt to the evolving landscape of higher education management. The demand for globally-minded leaders who can demonstrate value addition is increasing, necessitating a shift towards more effective and efficient practices. This pa
0 views • 23 slides
STRESS-L Trial: Study on Reversal of Septic Shock with Landiolol
The STRESS-L Trial focuses on reversing septic shock using Landiolol, a beta-blockade treatment. It provides training for non-GCP trained clinicians involved in eligibility review, medical care, and prescribing in the trial. The slides cover key GCP principles, trial agenda, study information, backg
2 views • 42 slides
Comparative Effectiveness Study of Second-Line Agents in Status Epilepticus Treatment: ESETT Trial
Comparative effectiveness study known as ESETT Trial aims to determine the most effective second-line agent for treating benzodiazepine-refractory status epilepticus in emergency departments. Fosphenytoin, valproic acid, and levetiracetam are common choices, but the best option remains uncertain. Th
0 views • 48 slides
Mastering Objection Handling and Negotiation Strategies: A Comprehensive Meeting Plan
Enhance your team's performance with a 4-week guided meeting plan focusing on objection handling and negotiation strategies. The plan includes pre-learning resources, team challenges, personality type reflection, and practical role-playing exercises. Dive into understanding different personality typ
0 views • 10 slides
DRAGON Trial: Green Surgery Research Programme Overview
Dmitri Nepogodiev, a Clinical Lecturer in Public Health at the University of Birmingham, leads the DRAGON Trial aiming to compare the effectiveness and sustainability of reusable versus single-use drapes and gowns in surgical settings. With a focus on reducing surgical site infections, carbon footpr
0 views • 9 slides
The CLEAR Trial: Investigating Hypertonic Saline and Carbocisteine in Bronchiectasis
The CLEAR Trial is a 2x2 factorial randomized trial evaluating the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the trial focuses on clinical and c
0 views • 23 slides
Challenges Faced by Judicial Officers in Court and Case Management
Judicial officers encounter difficulties in court and case management, including expeditious disposal, control over cases, discouraging wasteful pre-trial activities, and fixing schedules for applications, replies, and disposal. The process involves initial case management conferences, timely comple
7 views • 25 slides
ACST-2 Trial: Stenting vs. Surgery for Carotid Artery Stenosis
ACST-2 is a randomized trial comparing carotid artery stenting (CAS) versus carotid artery surgery (CEA) in asymptomatic patients with severe carotid stenosis. The trial, published in The Lancet in August 2021, involved 3625 patients. While surgery has been shown to reduce stroke rates, modern medic
0 views • 19 slides
Understanding the Criminal Trial Process
The Sixth Amendment guarantees various rights during criminal trials, such as a speedy and public trial, trial by jury, notice of accusations, the right to confront witnesses, and the assistance of counsel. Defendants can opt for a bench trial where the judge decides innocence or guilt. Juries, typi
0 views • 33 slides
DAPA-HF Trial: Dapagliflozin in Heart Failure Patients without Diabetes
The DAPA-HF trial investigated the use of dapagliflozin, an SGLT2 inhibitor, in patients with heart failure and reduced ejection fraction, regardless of diabetes status. Funded by AstraZeneca, the study enrolled 4,744 patients from 20 countries, showing promising results in reducing cardiovascular d
3 views • 22 slides
Overhead Analysis of Coordinated Spatial Reuse in IEEE 802.11-23
Analysis of overhead components impacting the performance of Coordinated Spatial Reuse (Co-SR) in IEEE 802.11-23 standard for wireless communication. Evaluation of MAC overhead, negotiation and measurement phases, and frames in the negotiation phase. Discussion on the impact of overhead on Co-SR per
0 views • 14 slides
Expert Mediation and Negotiation Services
Looking for a Mediation and Negotiation Specialist? Michael Gregory provides expert conflict resolution services, helping businesses and organizations navigate disputes with effective mediation and negotiation strategies. Whether it's business-to-bus
1 views • 5 slides
Mastering Salary Negotiation in the Modern Workplace
Explore insights on salary negotiation in the age of transparency, including why women hesitate to ask for raises and how to overcome such challenges. Learn essential tips for effective negotiation, such as research, authenticity, and timing strategies to close the gender pay gap.
0 views • 16 slides
The CLEAR Trial: Investigating Hypertonic Saline and Carbocisteine in Bronchiectasis
The CLEAR Trial is a 2x2 factorial randomized trial examining the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the study focuses on exacerbation ma
0 views • 16 slides
NCI-MATCH Trial Interim Analysis Results and Status Update
NCI-MATCH is a groundbreaking clinical trial aiming to match tumor gene alterations with targeted therapies. The interim analysis results revealed impressive patient enrollment and site participation exceeding expectations. Despite challenges with pausing new patient registrations for the analysis,
0 views • 26 slides