Peripheral Arterial Disease (PAD), a condition caused by reduced blood flow in the legs or arms. Understand the symptoms, signs, importance of early detection, and who is at risk. Find out about the tests for PAD.

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The natural history of disease development outlines the progression of a disease in an individual without intervention, from exposure to outcome. Learning objectives include defining prevention terms, understanding disease severity, prevention levels, and intervention measures. Studying disease prog

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Echocardiographic assessment plays a crucial role in the diagnosis, management, and prognostic evaluation of pulmonary arterial hypertension (PAH). This condition is characterized by elevated mean pulmonary arterial pressure and pulmonary vascular resistance, leading to various clinical features suc

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This UK-wide clinical trial aims to assess the effectiveness of early peripheral norepinephrine infusion in adult patients with septic shock. The study will compare the impact on mortality and other outcomes of targeting a mean arterial pressure (MAP) above 65mmHg within the first 48 hours of admiss

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Epidemiology is the study of disease patterns, factors influencing disease occurrence, and the core functions of surveillance, field investigation, and analytic studies. It involves understanding disease characteristics, natural history, and evaluating the effectiveness of activities to mitigate dis

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The brain receives its blood supply from four major arteries - two vertebral arteries and two internal carotid arteries. The vertebral arteries branch into the basilar artery, which gives rise to various important branches. The internal carotid arteries supply the anterior and middle cerebral arteri

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The article discusses the physiological basis, types, pathogenesis, and genetic predisposition of hypertension. It explains the revision of terminology related to blood pressure and the calculation of mean arterial pressure. Secondary hypertension, causes, and mean arterial pressure determination ar

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Cell membranes consist of phospholipid bilayers with embedded proteins, including integral and peripheral proteins. Integral proteins span the membrane, while peripheral proteins interact with the surface. Only non-polar molecules can pass through the membrane directly, while charged ions, polar mol

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Explore the intricate details of coronary circulation, including arterial supply, branches of coronary arteries, and areas of distribution. Dr. Abeer Al-Masri, an Associate Professor and Cardiovascular Physiologist at the Faculty of Medicine, KSU, provides valuable insights on the topic, covering th

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Learn about computer peripheral devices, which enhance a computer system's functionality. Examples include mice, keyboards, monitors, printers, and scanners. These devices can be categorized into input, output, and storage devices, each serving a specific purpose to expand the capabilities of your c

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Tyzzer's disease is an acute bacterial infection affecting rodents and rabbits, caused by Clostridium piliforme. Discovered in 1917 by Ernest Tyzzer, the disease is characterized by necrotic lesions in the caecal mucosa, liver, and heart. Initially known as Bacillus piliformis, it was later renamed

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In this detailed presentation by Dr. Sushma Tomar, Associate Professor of Anatomy, the intrinsic muscles of the tongue are explored, along with their functions, arterial and venous supply, lymphatic drainage, and nerve supply. The lecture covers the four intrinsic muscles in each half of the tongue,

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The cardiac cycle, involving systole and diastole processes, consists of arterial and ventricular events essential for heart function. Arterial events include systole and diastole, while ventricular events encompass isometric contraction, ejection period, prodiastole, isometric relaxation, rapid fil

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The study analyzed transcriptomic changes in peripheral blood mononuclear cells of International Space Station crew members. Blood samples were collected before and after spaceflight, and differentially expressed genes were identified using RNA-seq analysis. Several genes, including CDKN1A (p21) and

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This article discusses disease control processes in epidemiology, including reducing disease incidence, duration, and transmission. It covers public policy interventions, elimination, eradication, and extinction of infectious agents. It also highlights preventable causes of disease and different lev

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Cyanosis is characterized by a bluish discoloration of the skin and mucous membranes due to increased levels of reduced hemoglobin. This condition can be categorized as central or peripheral cyanosis, each with distinct characteristics and causes. Central cyanosis results from decreased oxygen satur

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The provided guidelines outline the standard care pathway for assessing peripheral lesions in lung cancer patients based on staging CT findings. It includes recommendations for biopsy methods, fitness assessment, PET-CT imaging, and considerations for treatment decisions. The protocol emphasizes tai

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Assessing patients with peripheral lesion on staging CT with normal hilar and mediastinal findings. Further investigation with contrast-enhanced CT is recommended for fitness evaluation and treatment planning. Biopsy methods, diagnostic criteria, and considerations for nodules and nodal staging are

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The study discusses strategies to limit speeding opportunities on arterial streets, particularly focusing on the impact of traffic signal coordination on reducing speeding incidents. Results from simulation tests and real-world observations are presented, highlighting the effectiveness of signal con

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This article discusses various vascular access methods in infants and children, including peripheral IV access, central venous access, arterial lines, and ultrasound-guided techniques. It covers indications, sites, complications, and techniques for each method, emphasizing the importance of proper a

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This informative content details the histo-anatomy of blood vessels, pathophysiology of atherosclerosis, peripheral ischemia, and carotid artery disease. It covers the definition, risk factors, and processes involved in atherosclerosis, including endothelial cell function, blood flow dynamics, and f

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Peripheral Arterial Disease (PAD) refers to the narrowing of blood vessels outside the heart and brain, leading to reduced blood flow. This condition can result from atherosclerosis, inflammation, embolism, or thrombus formation. Learn about the causes, symptoms, diagnosis, and treatment strategies

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Discussing the challenges and gaps in the medical management of PAD, this presentation by Dr. Faisal Latif highlights the unique issues faced by patients with PAD and the limitations of current treatment options. It delves into the current guidelines for symptomatic PAD and explores the findings of

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Patients with coronary artery disease should be screened for peripheral vascular disease as it is a frequent integrator of global cardiovascular risk. The association of atherosclerosis in various arterial diseases highlights the importance of identifying multisite artery disease. The prevalence and

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The Human Disease Symptom Network (HSDN) is constructed using a large-scale medical bibliographic records database to form a network of human diseases based on symptom similarities. By integrating disease-gene associations and protein-protein interaction data, correlations between symptom similarity

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The cardiovascular system includes the heart, arteries, veins, and capillaries, responsible for the transport of blood and lymph throughout the body. Arterial blood vessels are classified based on diameter into large (elastic) arteries, medium (muscular) arteries, and arterioles. The arterial wall c

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The study delves into verbal mismatch and phonological identity in peripheral ellipsis, covering topics such as syntactic mismatches, peripheral ellipsis and mismatch, and stricter identity requirements in peripheral ellipsis compared to other types of ellipsis. Various examples and analyses are pre

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Columnaris disease, also known as Saddleback disease, is a common bacterial infection in fish that is often brought about by poor handling and high stress levels. This disease manifests as tail and fin rot, leading to rapid fish mortality. The causative organism, Cytophaga (formerly Flexibacter), is

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Peripheral nerves play a vital role in connecting the central nervous system to various parts of the body. Injuries to these nerves can result from different causes, leading to significant challenges. Early intervention is crucial in preventing irreversible damage and improving outcomes. The process

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Arterial blood gases (ABG) are obtained from arteries to assess acid-base balance and blood oxygen levels. The pH, PaCO2, PaO2, HCO3, and SaO2 are crucial values on an ABG report. These values reflect the blood's acid-base status, carbon dioxide levels, oxygen saturation, and more. The buffer system

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Explore the latest findings from the Alzheimer's Disease Genetics Symposium 2019 on disease mechanisms, drug targets, and genetic pathways. Dive into the progress made by the Alzheimer's Disease Genetics Consortium over the past decade. Transition to a Genome-Wide Association Study uncovering suscep

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Dr. Somen Banerjee, Director of Public Health in London Borough Tower Hamlets, highlights the concerning liver disease mortality rates in the area, with high incidence of cirrhosis, cancer, and hepatitis B and C. The data reveals a significant burden of liver diseases such as Non-Alcoholic Fatty Liv

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Inflammatory Bowel Disease (IBD) encompasses Crohn's disease (CD) and ulcerative colitis (UC), chronic conditions with immunologic basis. This article delves into the epidemiology, pathophysiology, and differences between CD and UC, highlighting clinical features, pathology, and complications like a

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Central vs peripheral blood pressure differences have clinical implications as systolic pressure amplification occurs due to changes in arterial stiffness moving away from the heart. Central pressure measurements, more closely related to cardiovascular events, provide valuable insights for assessing

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Pulmonary Arterial Hypertension (PAH) is a progressive disease characterized by increased blood pressure in the pulmonary artery, veins, or capillaries. This condition can lead to right ventricular failure and eventual death if left untreated. PAH can have various causes, including idiopathic factor

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This article delves into the intricate mechanisms that regulate food intake and appetite, focusing on central and peripheral factors. Neural signals, gastric distention, glucose influence, circulating lipids' role, and gut hormones all play crucial roles in shaping our eating behavior. These signals

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Fabry's disease is a rare X-linked lipid storage disorder characterized by deficient lysosomal alpha-galactosidase A activity. This condition primarily affects males, leading to chronic kidney disease and progression to end-stage renal disease. Kidney involvement is a critical aspect, and high doses

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This presentation discusses the COST Action CA18214 focusing on new working spaces (NeWSp) and their role in promoting regional competitiveness, entrepreneurial environments, social inclusion, and spatial regeneration in peripheral areas. It explores the structure of the presentation, types of third

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Blood collection is a crucial process in medical investigations where blood is withdrawn from patients for analysis. Methods include arterial sampling, venipuncture, and fingerstick sampling, each serving specific purposes. Venous blood is preferred over arterial blood due to accessibility and ease

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Explore different types of peripheral nerve injuries including Erb's palsy, Klumpke palsy, isolated axillary nerve injury, and isolated musculocutaneous nerve injury. Learn about the anatomy, causes, motor and sensory exams, and management of these injuries. Understand the myotomes and dermatomes as

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