Structural divisions of the central and peripheral nervous systems, learn about neuron anatomy, the neuromuscular junction, and the role of neurotransmitters. Includes information on Acetylcholine, Norepinephrine, Dopamine, and Serotonin.

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The evidence-based science and clinical management of Cardiovascular-Kidney-Metabolic Syndrome (CKM) in this comprehensive slide set. Learn about the pathophysiological interactions, multi-organ dysfunction, and adverse cardiovascular outcomes associated with CKM.

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The increased risk of cardiovascular disease in people with HIV and specific strategies to treat it. This presentation discusses potential mechanisms, comorbidity gaps, and the impact of traditional risk factors. Explore the role of inflammation and immune dysfunction in atherosclerosis and vulnerab

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Steatotic liver disease, including metabolic dysfunction associated steatohepatitis (MASLD) and metabolic associated alcoholic liver disease (MALD), is a common cause of liver test abnormalities in the United States. Risk factors such as obesity and metabolic syndrome can lead to advanced fibrosis a

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Shock is a critical condition caused by an imbalance between cellular oxygen supply and demand, leading to organ dysfunction. Compensatory responses include increased heart rate, vasoconstriction, and hormonal adjustments. Recognizable features of shock include tachycardia, hypotension, cool clammy

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Pituitary disorders, often caused by tumors, can disrupt hormone production leading to various symptoms like weight gain, vision problems, and hormonal imbalances. The pituitary gland plays a crucial role in regulating bodily functions through hormone secretion. Factors such as tumor growth, head in

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Neuropsychological assessment plays a vital role in understanding brain-behavior relationships. This process involves determining cerebral functioning, identifying dysfunction, and assessing cognitive abilities through a combination of interviews, observational data, and testing. The assessment aids

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The Bleeding Time (BT) test evaluates platelet plug formation and capillary integrity, crucial for surgery preparations. Prolonged bleeding times indicate low platelet count or dysfunction. The Duke method is one way to determine Bleeding Time. Sources of error, such as medication interference, impr

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This study explores the use of CSL-112 infusions in patients with acute myocardial infarction to enhance high-density lipoprotein (HDL) function. By focusing on improving HDL-C function through ApoA-1 infusions, the research aims to enhance outcomes associated with cardiovascular events. The efficac

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The kidney is a two-bean-shaped organ in the human body that filters waste products, excess fluids, and poisons from the blood. It also contributes to overall health by controlling blood pressure, electrolyte balance, and red blood cell synthesis. But certain medical diseases, such as chronic kidney

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Cystic Fibrosis (CF) is a genetic disease caused by variants in the CFTR gene. CFTR is a crucial membrane protein responsible for chloride transport in epithelial cells, impacting organ function. The Modulator Era focuses on CFTR modulators approved by the FDA for treating CF and improving outcomes.

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Acute calculous cholecystitis is a common digestive disease with varying treatment perspectives. The Tokyo Guidelines 2018 provide criteria and severity grading for the diagnosis of acute cholecystitis. Diagnosis involves local and systemic signs of inflammation along with specific imaging findings.

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Amyloidosis is a disorder characterized by the deposition of abnormal amyloid fibrils in tissues, impacting various organs. This condition is associated with different types of amyloid, such as AA and AL amyloid. The deposition of amyloid can lead to tissue damage and organ dysfunction. Primary and

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Posterior Tibialis Tendon Dysfunction, also known as Adult Acquired Flat Foot Deformity (PTTD), is a condition that affects the tibialis posterior tendon, leading to reduced arch support. Common causes include obesity, trauma, age, and existing health conditions. Symptoms may include ankle pain, swe

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Sexual dysfunction encompasses a range of issues that can affect individuals, with causes including psychological, neurological, hormonal, and relationship-related factors. Evaluating sexual problems involves considering duration, context, and frequency. Psychological causes, such as anxiety and str

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Discover the intricate anatomy of the spine, learn about the prevalence and causes of lower back pain, delve into the symptoms and diagnosis of sacroiliac joint dysfunction, and explore treatment options to manage this condition effectively.

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This study compares the effectiveness of head ultrasounds and brain MRIs in detecting low-grade hemorrhages in preterm infants. It discusses the incidence of intraventricular hemorrhage (IVH) in very low birth weight infants, classification of IVH, risk factors for IVH, outcomes related to IVH grade

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This summary file covers the key aspects of trauma management, including epidemiology of trauma, mechanisms of injury (penetrating and blunt), triage and severity scoring, primary survey with ABCDE approach, emergency department management per ATLS protocol, and adjuncts to primary survey. It emphas

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SIREN is a collaborative network enabling high-quality, multi-site clinical trials for patients with neurologic, cardiac, respiratory, hematologic, and trauma emergencies. It consists of Clinical Coordinating Center, Data Coordinating Center, and 11 Clinical Centers with affiliated satellites. The n

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Neonatal seizures are sudden changes in neurologic function of a newborn, involving motor, behavior, and autonomic functions. The pathophysiology includes delays in Na/K ATPase maturation, increased receptor density, and GABAergic transmission. Different types of seizures like subtle, clonic, tonic,

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Movement dysfunction in sports medicine can stem from various factors such as structural instability, loss of range of motion, functional rigidity, poor balance, and more. Clinical movement analysis plays a vital role in identifying muscle imbalances and guiding exercise interventions to enhance ath

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Zika virus is a mosquito-borne infection that can lead to birth defects and neurologic disorders. It spreads through mosquito bites and can also be transmitted from mother to child during pregnancy or through sexual contact. The virus is prevalent in South and Central America, the Caribbean, and is

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Executive Functioning is a key aspect of cognitive function, encompassing various abilities such as planning, self-awareness, and emotion regulation. Executive Dysfunction, often resulting from frontal lobe injuries, can lead to difficulties in decision-making, social interactions, and learning. Thi

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Head injuries pose a significant threat to morbidity and mortality, with causes ranging from motor accidents to child abuse and falls. Understanding the epidemiology and pathophysiology of head injuries is crucial for effective management. Primary and secondary brain injuries necessitate immediate c

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An intriguing case study presents a young male with weakness and coma in the ICU following pneumonia and sepsis. Nerve conduction results indicated critical illness myopathy and polyneuropathy, along with cardiac abnormalities. Reduced muscle excitability was attributed to a sodium channelopathy. Th

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This consensus statement by the American Head and Neck Society Endocrine Surgery Section highlights the importance of recognizing immediate vocal fold paralysis (VFP) and partial neural dysfunction (PND) following thyroid and parathyroid surgery. The report emphasizes the need for early identificati

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Understanding cognitive dysfunction in cancer patients is crucial for improving quality of life and medical outcomes. This article explores the background, causes, screening, diagnosis, and treatment options for cancer-related cognitive impairment, emphasizing the historical perspective, prevalence,

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Boxing is gaining popularity in physical therapy for addressing orthopedic and neurologic conditions. It offers benefits such as movement coordination, balance training, and confidence-building. Research indicates its effectiveness for conditions like cancer, stroke, multiple sclerosis, and Parkinso

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Neonatal seizures are a critical sign of neurologic dysfunction in newborns, with various types such as subtle, clonic, tonic, spasms, and myoclonic seizures. The immature brain's excitability and differences from the mature brain predispose neonates to seizures. Generalized clonic seizures are rare

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Abstracts from CROI 2021 selected by Gilead highlight treatment effects on neurologic outcomes, drug interactions, clinical trials of antiretroviral therapy, and new developments in drug resistance. Additionally, the session on Lenacapavir (GS-6207) presents promising data on this long-acting HIV ca

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Discover how PDE-5 inhibitors go beyond treating erectile dysfunction, with approved and emerging compounds, alternative dose regimens, concentration sites, and potential targets like cardiovascular diseases and the central nervous system.

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In the Senior Driver Summit breakout session, Cody Stovall discussed the warning signs of high-risk drivers, emphasizing the importance of clinical driver assessments for older drivers. The program established in 1998 evaluates older drivers with cognitive decline, new drivers needing adaptations, a

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Radioactive iodine (RAI) is commonly used in treating differentiated thyroid cancer but can lead to salivary and lacrimal dysfunction. This joint clinical consensus statement by the American Head and Neck Society Endocrine Surgery and Salivary Gland Sections highlights the importance of understandin

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This research explores mapping the MMPI-2-RF substantive scales onto internalizing, externalizing, and thought dysfunction dimensions in mental health assessment. The study emphasizes the importance of validating assessments for accurate clinical pictures and effective treatment planning. It delves

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Pelvic floor dysfunction and prolapse are common issues affecting women, impacting their physical and emotional well-being. Surgical treatment may be necessary for symptomatic cases, but a thorough evaluation of symptoms, obstetric history, and other factors is crucial. Addressing precipitating fact

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Cardiorenal Syndrome is a condition where dysfunction in one organ, whether acute or chronic, can lead to dysfunction in the other. This complex relationship involves intricate communication pathways between the heart and kidneys, impacting hemodynamic stability, organ perfusion, and neurohormonal i

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Coronaviruses are single-stranded RNA viruses that infect birds, mammals, and humans. They can cause respiratory and enteric diseases, hepatitis, and neurologic issues. Initially of veterinary interest, coronavirus spread has escalated into human-to-human transmission. WHO recommends handwashing, co

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The research explores the association between taste perception and the duration of COVID infection in long-COVID and COVID-reinfection cases. Reduced salivary gustin levels correlated with lower taste scores in long-COVID patients. The study also found an increase in the bitter taste receptor gene e

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Primary ovarian insufficiency, also known as hypergonadotropic amenorrhea, is a condition characterized by ovarian dysfunction in women under 40. It involves oligo/amenorrhea, elevated FSH levels, and impacts fertility and overall health. The pathophysiology includes follicle depletion and dysfuncti

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Understanding the crucial role of airway management in the NeuroICU is essential for preventing secondary brain injury and addressing respiratory complications in neurologically-injured patients. This presentation covers the significance of airways, common issues, evaluation techniques, adjuncts, an

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