Gwas implementation - PowerPoint PPT Presentation


Data QC / cleaning in Genome-Wide Association Studies (GWAS)

Daniel Howrigan, Data group leader at Neale Lab (MGH, Broad Institute), for a workshop on data QC and cleaning in GWAS. Learn about goals of GWAS, genetic data visualization, QC methods, and more.

2 views • 35 slides


Addressing the Misuse of Biology and Bioterrorism Through National Implementation

Dr. Irma R. Makalinao presents on national implementation strategies to combat the misuse of biology and bioterrorism, leveraging cooperation, assistance, and regional activities. Objectives include showcasing examples of effective national implementation, offering assistance to the Philippines, and

2 views • 22 slides



Implementing TeamSTEPPS: Introduction and Implementation Process

Explore the journey of implementing TeamSTEPPS - a framework to enhance communication and teamwork in healthcare settings. Dive into pre-implementation activities, readiness assessment, change management principles, and coaching techniques. Understand the importance of addressing organizational cult

1 views • 80 slides


Comprehensive Marketing Process Implementation Plan Presentation

This comprehensive marketing process implementation plan template is designed to guide project teams through the phases of project execution. It includes detailed tasks, timelines, milestones, and phases to ensure successful implementation. The plan covers key aspects from initial project setup to f

5 views • 7 slides


Evaluation of Home-Based Sexual Health Care Implementation Among Men Who Have Sex with Men Using the RE-AIM Framework

This study evaluates the implementation of home-based sexual health care for men who have sex with men, emphasizing the importance of a systematic approach for effective integration. The research focuses on developing and implementing home-based care to address inequities in access to universal huma

3 views • 12 slides


Understanding Genome-Wide Association Studies in Statistical Genetics Workshop

Explore the essentials of Genome-Wide Association Studies (GWAS) and genetic data quality control as presented by Daniel Howrigan in the 2023 workshop. Delve into the goals of GWAS, genetic data characteristics, SNP variations, and genotyping techniques. Gain insights into moving from trait heritabi

0 views • 35 slides


Top-Quality SAP Implementation Services in India by Infront Technology

For companies of all sizes, Infront Technology provides excellent SAP implementation services in India that guarantee smooth SAP system integration and optimization. Our knowledgeable staff specializes in providing specialized SAP implementation services in India that are suited to each individual c

0 views • 4 slides


Training Requirements and Implementation Project Overview

This document outlines the training requirements and implementation steps for the Special Implementation Project in AIDC Bangkok. It covers general steps for developing simulations and procedures, specific training needs for ATCOs, FDOs, ATSEPs, and other staff, as well as understanding system roles

0 views • 8 slides


Bioinformatics for Genomics Lecture Series 2022 Overview

Delve into the Genetics and Genome Evolution (GGE) Bioinformatics for Genomics Lecture Series 2022 presented by Sven Bergmann. Explore topics like RNA-seq, differential expression analysis, clustering, gene expression data analysis, epigenetic data analysis, integrative analysis, CHIP-seq, HiC data,

0 views • 36 slides


Understanding Implementation Science: Bridging Research and Practice

This content delves into the principles of implementation science, discussing its significance, outcomes in research, and strategies to enhance the adoption of evidence-based practices. It defines key terms like dissemination and implementation, emphasizing the active approach to behavior change. Si

0 views • 32 slides


Challenges in Standard QUIC Protocol Implementation

The content discusses the challenges and shortcomings of the standard QUIC protocol implementation, focusing on the use of TLS 1.3 for cryptographic handshake. It highlights issues such as complexity in implementation and state machine, lack of a full security proof, and the risk of ossification due

0 views • 108 slides


Evolution of Public Policy Implementation Studies

Implementation studies focus on policy change and translating policies into action. These studies emerged in the 1970s in the United States, with different generations highlighting the challenges and approaches to policy implementation. The evolution of top-down, bottom-up, and hybrid theories in im

1 views • 24 slides


Innovative Development in High Stearic Acid Soybean Germplasm Breeding at University of Missouri Delta Center

Innovative research on developing high stearic acid soybean germplasm is being conducted at the University of Missouri Delta Center. Challenges in breeding high stearic soybeans, such as sodium azide-induced deletions and mutant alleles in SACPDs, are being addressed. Promising lines identified from

1 views • 9 slides


Parallel Implementation of Multivariate Empirical Mode Decomposition on GPU

Empirical Mode Decomposition (EMD) is a signal processing technique used for separating different oscillation modes in a time series signal. This paper explores the parallel implementation of Multivariate Empirical Mode Decomposition (MEMD) on GPU, discussing numerical steps, implementation details,

1 views • 15 slides


Community Project Implementation Structures in Gulf of Guinea Northern Regions

The Gulf of Guinea Northern Regions Social Cohesion (SOCO) Project involves the selection and role of community facilitators and Community Project Implementation Committees (CPICs) to facilitate project implementation in clusters of communities. Various committees and structures at national, regiona

2 views • 14 slides


Meta-Analysis in GWAS: Methods and Applications

Meta-analysis in GWAS involves combining data across studies to estimate overall effects, explore cohort differences, improve power, and replicate findings. It includes joint vs. meta-analysis, methods, and types such as fixed effect and random effect meta-analyses.

0 views • 20 slides


Precision Implementation Approach in Evidence-Based Practice

Implementation is a complex step in Evidence-Based Practice (EBP) process with various strategies for effective and sustainable change. Utilizing local data-driven decisions, the Precision Implementation Approach selects accurate strategies for successful EBP outcomes. Linking process and outcome da

0 views • 18 slides


Policy Implementation in Uganda: Evidence and Challenges

This research delves into the implementation of policies in Uganda with a focus on insights from previous Economic Growth Forum (EGF) recommendations. Analysts like Milly Kaddu and Ramathan Ggoobi highlight the importance of a dedicated policy on implementation. Methods for assessing policy progress

1 views • 12 slides


Polymorphism and Variant Analysis Lab Exercise Overview

This document outlines a lab exercise on polymorphism and variant analysis, covering tasks such as running Quality Control analysis, Genome Wide Association Test (GWAS), and variant calling. Participants will gain familiarity with PLINK toolkit and explore genotype data of two ethnic groups. Instruc

0 views • 43 slides


Update on ESCO Implementation in EURES

The update on ESCO implementation in EURES includes information on mapping tables submission, ESCO implementation process, mapping adoption across EURES countries, pending ESCO implementation in specific countries, and the state of job vacancies encoding with ESCO URIs. It outlines the progress, cha

0 views • 12 slides


Understanding Small Area Fair Market Rents (SAFMR) Implementation Webinar

This webinar recording discusses the implementation of Small Area Fair Market Rents (SAFMR), which offer a more refined approach to housing choice voucher subsidy implementation by replacing Metropolitan Area Fair Market Rents. It covers the background, reasons for the 2019 implementation, options f

1 views • 26 slides


Challenges in Policy Implementation and Lessons Learned

The content discusses the challenges faced in policy implementation, focusing on the gap between policy design and execution. It highlights key steps in policy-making, reasons for implementation failures, and factors influencing successful policy outcomes. Examples from Zambia's National Science and

0 views • 14 slides


Utilizing Direct Observation for Implementation Facilitation

This article discusses the importance of direct observation in guiding implementation facilitation processes. It emphasizes the value of formative evaluation to identify influences on implementation effectiveness. By thoroughly collecting data through mixed-methods direct observation, facilitators c

1 views • 29 slides


PBN Planning and Implementation Status in Ukraine

The PBN Planning and Implementation status in Ukraine involves initiatives such as the implementation of Precision Area Navigation (P-RNAV) and Approach Procedures with Vertical Guidance (APV). Ukraine is working on national RNAV1 implementation for standard instrument procedures at various aerodrom

1 views • 17 slides


Overview of Ethio-SHEP Project Team and Implementation Structure

The Ethio-SHEP project aims to strengthen extension services using a market-oriented approach. The project team includes Japanese experts and Ethiopian national staff, each with specific roles and responsibilities. Implementation is structured based on the existing government setup, with focal perso

1 views • 12 slides


City of Oakland Finance Dept. Public Outreach Session - Measure W Vacant Property Tax Implementation Ordinance

The City of Oakland Finance Department conducted a public outreach session on the implementation of Measure W, a vacant property tax ordinance. The session aimed to receive public input, provide an overview of the tax and exemptions, and outline the implementation process. Measure W, approved by cit

0 views • 11 slides


Strategic Plan for Implementation

Coordinating actions to leverage financial and political support, the plan build process involves workshopping key chapters and drafting plan content for review and refinement by the planning team and working group. Principles for developing the implementation plan focus on maximizing outcomes, addr

0 views • 14 slides


Overview of IFRS Implementation in Japan

The overview of IFRS implementation in Japan includes the voluntary and mandatory phases, benefits for companies, challenges faced during implementation, and future plans for mandatory adoption. The process involves transitioning from Japanese standards to IFRS, with a focus on reducing funding cost

1 views • 16 slides


CAP Implementation Progress in Mali-Meteo and Fast-Tracking in Africa

The Common Alerting Protocol (CAP) implementation in Mali-Meteo by Ismahila Koumare has been significant, with successful alert issuance since 2021. Collaboration with WMO and efforts to fast-track CAP implementation in five African countries show progress and challenges. Mali-Meteo has used cloud-b

0 views • 9 slides


Statistical and Quantitative Genetics of Disease: Understanding Population Stratification

This lecture explores the use of summary statistics to assess population stratification and the impact of LD on association studies in statistical and quantitative genetics. It delves into LD scores, genomic inflation, polygenic inheritance, and separating SNP heritability from population stratifica

0 views • 29 slides


Star-AI for Genetic Data Analysis: Incorporating Knowledge in Statistical Modeling

Knowledge-based approaches are crucial in genetic data analysis to enhance the accuracy and scope of genome-wide association studies (GWAS). Stochastic Relational AI (Star-AI) offers a solution by leveraging probability theory and First Order Logic to capture complex genetic interactions. By integra

0 views • 10 slides


Genomic Imputation Pipeline Overview

This document outlines a genomic imputation pipeline for multiple GWAS studies using reference panels such as 1000 Genomes Phase I data. It covers steps like data matching, phasing, and imputation using tools like Beagle and Minimac. The expected output includes imputed dosages and quality measures.

0 views • 6 slides


HIT Implementation Planning for Quality and Safety Lecture

This material, developed by Johns Hopkins University and funded by the Department of Health and Human Services, focuses on HIT implementation strategies for quality and safety improvement. It covers topics such as big bang vs. staggered approaches, go-live support, maintenance strategies, contextual

0 views • 23 slides


Implementation of Medication Assisted Treatment Standards and Phases to Evidence Implementation

The Medication Assisted Treatment (MAT) Implementation Support Team (MIST) aims to enhance local teams' capacity to implement MAT standards through various methods including clinical QI, evidence collection, information governance, and leadership. The evidence implementation involves three phases: s

0 views • 6 slides


Understanding Policy Implementation Diagnostic Framework for Low Carbon Policies

Explore the Policy Implementation Diagnostic Framework designed to analyze institutional factors and enhance the effectiveness of low carbon policies. Discover the importance of addressing implementation deficits, creating enabling environments, and identifying practices for successful policy implem

0 views • 28 slides


Understanding Y Chromosomal Haplogroups in Genetic Studies

Exploring the utility of non-recombining paternal ancestry information in Genome-Wide Association Studies (GWAS) through the analysis of Y chromosomal haplogroups. This review delves into the implications of using Y chromosome and mitochondrial DNA data in tracing human migrations, ancestry, bottlen

0 views • 27 slides


Implementation Planning for Health Innovation in Clinical Settings

Dive into the experiential opportunity of preparing for the implementation of a health innovation in clinical settings with Allison Cole, MD, MPH. Explore options for operationalizing implementation and understanding your intervention. Engage in discussions on project progress, challenges, and next

0 views • 21 slides


Guide on Using BLINK C Version for Genetic Analysis

This guide provides step-by-step instructions on how to effectively use the BLINK C version for genetic analysis. It covers tasks such as preparing input files, handling phenotype and covariates data, implementing GWAS using BLINK, transforming genotype data, compressing to BLINK binary format, conv

0 views • 9 slides


Advancements in Statistical Genomics: FarmCPU and Method Development

Exploring the evolution of statistical genomics techniques, this lecture delves into the history of FarmCPU and BLINK, addressing challenges in GWAS and the development of models like PC+SNP+e and PC+Kinship+e. It also covers popular software packages in the field and the importance of moving beyond

0 views • 24 slides


Understanding Genomics and Bioinformatics in Genetics Evolution

Delve into the world of genomics and bioinformatics through the Genetics and Genome Evolution (GGE) lecture series by Sven Bergmann. Explore topics such as RNA-seq analysis, differential expression, gene expression measurement techniques, and integrative analysis with epigenetic data. Gain insights

0 views • 37 slides