Explore various physical and chemical methods used for gene transfer, including electroporation, particle bombardment, microinjection, ultrasound, and bacterial transformation. Learn how DNA enters the nucleus and the role of retroviruses in gene transfer efficiency. Understand the process of RNA co

0 views • 17 slides

This article provides insights into the status, regulatory considerations, and delivery methods of gene therapy and genome editing technologies. It discusses approved gene therapies in the US, human genome editing in clinical applications, and the regulatory authority of the FDA over gene therapy. T

3 views • 27 slides

Placement involves allocating individuals to jobs, including new hires and internal transfers, while induction is a structured introduction for employees to their roles and the organization. A well-designed induction program aims to familiarize employees with the organization's values, goals, and ta

3 views • 7 slides

The new SOGC Induction of Labor Guidelines 2023 were introduced at the Family Medicine Forum by Dr. Hannah Shenker and Dr. Helen Mavromichalis from McGill University. The presentation discussed various scenarios for inducing labor and highlighted key recommendations, including the importance of shar

0 views • 41 slides

Gene expression is a crucial process that leads to the production of functional gene products like RNA and proteins. This article explores the regulation of gene expression in both prokaryotes and eukaryotes, covering the importance of regulating gene expression, types of regulation elements, specif

5 views • 22 slides

Comprehensive overview of the FY1 Doctors Induction 2023-24 by Simran Sehdev, Lowri Foster Davies, Claire Barnett, and Peeyush Kumar. The induction covers various aspects such as the Med Ed website, team introductions, foundation programme booklet, Horus ePortfolio requirements, teaching sessions, P

0 views • 18 slides

The field of philosophy of science grapples with various issues, including the Problem of Explanation and the Problem of Induction. Aristotle's views on scientific explanation and the deductive-nomological model are discussed. The reliance on induction in science, drawing general conclusions from li

2 views • 11 slides

Gene set enrichment tests help identify functional gene sets enriched in hit lists compared to background sets. Various biases (technical, biological, statistical) can lead to incorrect conclusions in data analysis, emphasizing the importance of recognizing and addressing them. Technical biases like

0 views • 29 slides

Delve into the world of genetics and genomics through the lens of integrative biology, investigating the differences between cell types, the rationale for gene expression profiling, and the analysis of differential gene expression in various diseases. Uncover the significance of gene ontology, co-ex

0 views • 22 slides

This content provides information on the Summer Institutes of Statistical Genetics module, focusing on gene expression profiling. It includes details on the schedule, experimental design, RNA sequencing workflow, modes of bulk RNA sequencing, and RNASeq software. The content discusses crucial steps

0 views • 11 slides

Gene mutations play a significant role in molecular biology, leading to alterations in DNA sequences that can impact offspring. These mutations can arise spontaneously or be induced by various factors, such as mutagens. Understanding gene mutations is crucial for comprehending the genetic basis of c

2 views • 27 slides

An induction motor is comprised of a stator and rotor, with the stator featuring a 3-phase winding fed from a 3-phase supply. The rotor comes in two types - squirrel-cage and phase wound. The squirrel-cage rotor consists of heavy bars tightly pressed on the shaft, while the phase wound rotor has a 3

0 views • 47 slides

Gene drive technology is a cutting-edge approach aimed at combating malaria by spreading genetically modified genes in mosquito populations. This technology has the potential to protect endangered species and conserve nature. However, successful implementation requires complex collaborations, risk a

2 views • 16 slides

Gene therapy involves introducing DNA into a patient to treat genetic diseases by correcting disease-causing mutations. There are two types of gene therapy: somatic gene therapy and germline gene therapy, each with different implications. Techniques such as gene augmentation therapy and gene inhibit

1 views • 15 slides

Explore the mechanism of gene induction through the lac operon in Escherichia coli, where genes are switched on or off based on the presence of lactose. Learn how enzymes like β-galactosidase are produced only when needed, following the Jacob-Monod hypothesis. This system allows for efficient resou

3 views • 16 slides

Induction of labor is the artificial initiation of the labor process before it begins naturally. This procedure is performed in cases such as premature rupture of membranes, prolonged pregnancy, preterm premature rupture of membranes, pre-eclampsia, and maternal medical conditions like diabetes or c

1 views • 30 slides

This comprehensive content delves into the intricate mechanisms of gene regulation and control of gene expression. It covers topics such as transcriptional regulation, bacterial genes classification, and the role of regulatory proteins. Explore how genes are regulated at transcription, translation,

0 views • 17 slides

Explore the dynamic world of gene expression with the Chunky and Chips Gene Expression Group at the University of Notre Dame. Dive into topics like transcription, translation, and cellular events influencing gene expression. Delve into real-world scenarios and gain insights into the cellular level b

0 views • 20 slides

Delve into the realm of strong induction with a focus on computational concepts from CSE 311. Unveil the principles behind recursion, making induction proofs comprehensible, and the foundational Principle of Induction. Discover how to navigate complex algorithms and conquer challenges in the world o

0 views • 34 slides

Epistasis is a phenomenon where the phenotypic expression of one gene is influenced by interactions with another gene. This concept, first introduced in 1909, plays a crucial role in genetics, affecting various traits and evolutionary processes. The difference between dominance and epistasis lies in

0 views • 41 slides

Induction of parturition in mammals involves the essential roles of progesterone, luteal regression, fetal cortisol, and the shift from progesterone to estrogen. This process is crucial for saving the lives of both the dam and fetus. Corticosteroids like dexamethasone and flumethasone are commonly u

0 views • 10 slides

An informative guide for new inductees of the National Honor Society, including introductions to current officers, values, membership responsibilities, induction attire, and the induction process. Detailed instructions on attire, process at the cafeteria, and the ceremony itself are provided. The gu

0 views • 11 slides

Guidelines for buprenorphine induction and maintenance for patients dependent on short-acting or long-acting opioids. Covers microdosing, home vs. office induction, managing withdrawal symptoms, dose titration, patient education, and follow-up protocols. Includes information on assessing withdrawal,

0 views • 17 slides

Induction motors are widely used in various applications due to their advantages like robustness, high power-to-weight ratio, and low cost. However, they have limitations such as fixed speed operation. These motors consist of a stationary stator and a rotating rotor, with different designs like squi

0 views • 50 slides

An induction furnace utilizes a combination of electrical resistance and hysteresis losses to efficiently heat metal. By exposing the metal to a magnetic field created by a coil carrying alternating current, these enclosed structures provide a controlled environment for heating materials, gases, or

0 views • 19 slides

The CWVYS Induction Programme is a comprehensive initiative developed in partnership with Adult Learning Wales to equip volunteers, staff, and trustees in the field of youth work with essential skills, knowledge, and confidence. This programme, consisting of 9 units available in English and Welsh, c

0 views • 14 slides

Induction of labor is done to achieve vaginal delivery before spontaneous onset, usually at 39 weeks or when medically necessary. Risks include failed induction, cesarean section, uterine rupture, prolonged labor, and infections. Cervical ripening methods help prepare the cervix for labor. The Bisho

0 views • 18 slides

The Gene Wiki Jamboree FaceBase Spring Meeting in 2010 aimed to create collaboratively-written and community-reviewed review articles for every gene in the human genome and every concept relevant to FaceBase. It highlighted the value of such articles, providing quick summaries and compilations of re

0 views • 13 slides

Explore the foundations of automated knowledge base construction through taxonomy induction and entity disambiguation frameworks. Learn about organizing and distinguishing entity types, the significance of structuring entities like physicists, villages, and chemical formulas. Delve into the inputs,

0 views • 53 slides

Welcome to Guy's and St Thomas NHS Foundation Trust! This comprehensive local induction pack provides essential information and support for new junior doctors joining the Trust. From the excellent medical training to access to world-class research, this pack covers important aspects such as professi

0 views • 13 slides

This supplementary data includes raw data from agarose gel electrophoresis showing gene expression levels for human SOX17, FOXA2, AFP, ALB, and ACTB in various cellular samples. The gel images depict the expected sizes of amplicons for each gene in different conditions and time points of cell cultur

0 views • 5 slides

In this project, the focus is on identifying splice sites relevant to the inhibitory dopamine receptor gene (D2). The problem involves finding splicing elements within a specific range of known splice sites in the gene. The data provided includes the D2 gene entry in FASTA format, a database of spli

0 views • 13 slides

Reverse genetic approaches involve mutating a target gene to observe its phenotypic effects, providing insights into the gene's normal function. Techniques like gene knockout, knockdown, and homologous recombination are used to manipulate genes and study genetic pathways, leading to discoveries in v

0 views • 6 slides

Explore Faraday's Law of Induction, magnetic permeability, and the role of soft iron in strengthening magnetic fields. Learn about Faraday's idea of generating current from a magnetic field and his groundbreaking discovery of electromagnetic induction.

0 views • 25 slides

The lecture covers the essential aspects of hypothesis testing in gene expression profiling, emphasizing experimental design, confounding factors, normalization of samples, linear modeling, gene-level contrasts, t-tests, ANOVA, and significance assessment techniques. Practical insights are shared on

0 views • 9 slides

Exploring the fundamentals of genetics engineering, this lecture covers topics such as DNA structure, gene expression, gene function, genome, mutation, recombination, and genetic modification. Understand the significance of DNA, genes, and the processes involved in gene expression. Dive into the wor

0 views • 20 slides

Expression vectors are designed to facilitate gene expression by carrying essential elements such as promoters, terminators, and fusion tags. They allow precise control over gene regulation for transcription and translation in host cells, enabling efficient protein production. Different promoters li

0 views • 15 slides

In this project, the Cstps-1 gene from Citrus sinensis is being cloned to produce the enzyme Citrus Valencene Synthase (CVS) responsible for generating the fragrant valencene compound. The process involves DNA isolation from a Valencia orange, gene amplification, vector transformation, and testing f

0 views • 8 slides

Multiple enhancers play a crucial role in regulating gene expression in a cell, with approximately 3-5 enhancers associated per human gene. These enhancers are essential for tissue-specific expressions and are active within the same cell line. The use of multiple enhancers can impact gene expression

0 views • 30 slides

Workshop outcomes and discussions from the MDA-NINDS Workshop on Best Practices for Gene Therapy Programs, highlighting key challenges, possible solutions, and the impact on translational funding programs. The workshop format included orienting talks and panels focusing on scientific premise, regula

0 views • 17 slides