Acute pulmonary embolism (PE) is a significant issue in hospitalized patients, with current treatments focusing on anticoagulation and systemic thrombolysis. Surgical treatments have shown poor outcomes, leading to a rise in endovascular techniques aimed at reducing clot burden. A survey conducted i

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This educational content covers the basics of deep vein thrombosis (DVT) and pulmonary embolism (PE), including definitions, pathophysiology, risk factors, prevention strategies, diagnosis, and treatment. Traumatic and non-traumatic risk factors for VTE in orthopedic patients are discussed, emphasiz

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Understanding the mortality burden related to caesarean deliveries (CD) in South Africa, this report highlights the need for safe CD practices amidst high maternal death rates. Factors influencing safe CD, checklists for accreditation, and strategies for action plans are discussed. The Case Fatality

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A prespecified subanalysis of the NOAH-AFNET 6 trial evaluated the efficacy and safety of edoxaban anticoagulation in patients with Atrial High-Rate Episodes (AHRE) lasting 24 hours compared to shorter episodes. Findings suggest that oral anticoagulation with edoxaban does not significantly reduce t

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American Society of Hematology (ASH) released guidelines in 2020 for the management of Venous Thromboembolism, focusing on deep vein thrombosis and pulmonary embolism. These guidelines cover prevention, treatment, and optimal management strategies. The recommendations are developed through a rigorou

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Anne Knisely, a 69-year-old female with a history of endometrial cancer, presented with left leg pain, pleuritic chest pain, and shortness of breath. Imaging revealed extensive bilateral pulmonary emboli, right heart strain, and lower extremity deep vein thrombi. She was managed with anticoagulation

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A 69-year-old man with chest pain and pleural effusion presents with thromboembolism; a 22-year-old worker with fractures develops shock due to fat embolism; a postpartum woman dies from amniotic fluid embolism. The cases illustrate conditions like pulmonary embolism, fat embolism, and amniotic flui

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Adaptable and open clinical trial infrastructure emphasizing collaborative leadership with shared responsibilities for successful trial implementation and data integrity. Encourages respectful ownership by investigators while engaging with NIH and SIREN to develop and fund important trials, includin

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Peripheral Arterial Disease (PAD) refers to the narrowing of blood vessels outside the heart and brain, leading to reduced blood flow. This condition can result from atherosclerosis, inflammation, embolism, or thrombus formation. Learn about the causes, symptoms, diagnosis, and treatment strategies

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Thrombolytics are suggested for cardiac arrest from presumed PE despite lack of RCTs focusing on this subset. Studies on undifferentiated cardiac arrest did not show a survival benefit. Trials using tissue plasminogen activator in PEA arrest showed no significant difference in outcomes, while a stud

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Hemodynamics pathology lecture covers fat embolism, air embolism, amniotic fluid embolism, ischemia, and infarction. Each type of embolism has distinct causes and clinical features, leading to serious consequences. Understanding these conditions is crucial for proper management and prevention in med

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Postural drainage therapy is an intervention used for airway clearance by mobilizing secretions in specific lung segments towards the central airways. It involves placing the patient in various positions to facilitate gravity-assisted drainage. The therapy includes manual techniques such as percussi

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Embolism, defined as a detached intravascular mass carried through the blood, poses serious risks like pulmonary embolism. Venous thrombosis, particularly deep vein thrombosis (DVT), can lead to embolization, emphasizing the importance of understanding these mechanisms in medical practice.

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This comprehensive guide delves into the various aspects of shock, including hypovolemia, pulmonary embolism, and acute myocardial infarction. It covers the general concept of shock, circulatory failure, phases of shock, pathophysiology, manifestations, diagnostic approaches, and complications such

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