UK Survey on Endovascular Treatment of Acute Pulmonary Embolism
Acute pulmonary embolism (PE) is a significant issue in hospitalized patients, with current treatments focusing on anticoagulation and systemic thrombolysis. Surgical treatments have shown poor outcomes, leading to a rise in endovascular techniques aimed at reducing clot burden. A survey conducted i
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Understanding Venous Thromboembolism in Orthopedic Patients
This educational content covers the basics of deep vein thrombosis (DVT) and pulmonary embolism (PE), including definitions, pathophysiology, risk factors, prevention strategies, diagnosis, and treatment. Traumatic and non-traumatic risk factors for VTE in orthopedic patients are discussed, emphasiz
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Risks and Strategies for Safe Caesarean Deliveries in South Africa
Understanding the mortality burden related to caesarean deliveries (CD) in South Africa, this report highlights the need for safe CD practices amidst high maternal death rates. Factors influencing safe CD, checklists for accreditation, and strategies for action plans are discussed. The Case Fatality
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Efficacy and Safety of Anticoagulation with Edoxaban in Patients with AHRE Durations ≥24 Hours: The NOAH-AFNET 6 Trial
A prespecified subanalysis of the NOAH-AFNET 6 trial evaluated the efficacy and safety of edoxaban anticoagulation in patients with Atrial High-Rate Episodes (AHRE) lasting 24 hours compared to shorter episodes. Findings suggest that oral anticoagulation with edoxaban does not significantly reduce t
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ASH Guidelines 2020: Management of Venous Thromboembolism
American Society of Hematology (ASH) released guidelines in 2020 for the management of Venous Thromboembolism, focusing on deep vein thrombosis and pulmonary embolism. These guidelines cover prevention, treatment, and optimal management strategies. The recommendations are developed through a rigorou
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Understanding Hemostasis and Hemodynamic Disorders in Health
Hemostasis is crucial for maintaining the health of cells and tissues by ensuring continuous circulation of water, oxygen, and nutrients while removing metabolic waste products. Factors controlling normal hemostasis include the integrity of blood vessel walls, blood content, platelet function, and l
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Case Report: Submassive Bilateral Pulmonary Embolism in a 69-Year-Old Female
Anne Knisely, a 69-year-old female with a history of endometrial cancer, presented with left leg pain, pleuritic chest pain, and shortness of breath. Imaging revealed extensive bilateral pulmonary emboli, right heart strain, and lower extremity deep vein thrombi. She was managed with anticoagulation
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Pulmonary Conditions and Hemodynamic Disorders: Clinical Cases
A 69-year-old man with chest pain and pleural effusion presents with thromboembolism; a 22-year-old worker with fractures develops shock due to fat embolism; a postpartum woman dies from amniotic fluid embolism. The cases illustrate conditions like pulmonary embolism, fat embolism, and amniotic flui
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Streamlined Clinical Trial Infrastructure with Collaborative Leadership
Adaptable and open clinical trial infrastructure emphasizing collaborative leadership with shared responsibilities for successful trial implementation and data integrity. Encourages respectful ownership by investigators while engaging with NIH and SIREN to develop and fund important trials, includin
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Understanding Peripheral Arterial Disease (PAD) - Overview and Management
Peripheral Arterial Disease (PAD) refers to the narrowing of blood vessels outside the heart and brain, leading to reduced blood flow. This condition can result from atherosclerosis, inflammation, embolism, or thrombus formation. Learn about the causes, symptoms, diagnosis, and treatment strategies
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Thrombolytics in Cardiac Arrest from Pulmonary Embolism: Evidence Review
Thrombolytics are suggested for cardiac arrest from presumed PE despite lack of RCTs focusing on this subset. Studies on undifferentiated cardiac arrest did not show a survival benefit. Trials using tissue plasminogen activator in PEA arrest showed no significant difference in outcomes, while a stud
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Understanding Hemodynamics Pathology: Causes and Consequences of Various Embolisms
Hemodynamics pathology lecture covers fat embolism, air embolism, amniotic fluid embolism, ischemia, and infarction. Each type of embolism has distinct causes and clinical features, leading to serious consequences. Understanding these conditions is crucial for proper management and prevention in med
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Postural Drainage Therapy for Airway Clearance
Postural drainage therapy is an intervention used for airway clearance by mobilizing secretions in specific lung segments towards the central airways. It involves placing the patient in various positions to facilitate gravity-assisted drainage. The therapy includes manual techniques such as percussi
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Understanding Embolism and Venous Thrombosis in Mechanism of Disease
Embolism, defined as a detached intravascular mass carried through the blood, poses serious risks like pulmonary embolism. Venous thrombosis, particularly deep vein thrombosis (DVT), can lead to embolization, emphasizing the importance of understanding these mechanisms in medical practice.
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Understanding Shock: Causes, Phases, and Pathophysiology
This comprehensive guide delves into the various aspects of shock, including hypovolemia, pulmonary embolism, and acute myocardial infarction. It covers the general concept of shock, circulatory failure, phases of shock, pathophysiology, manifestations, diagnostic approaches, and complications such
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Comprehensive Guide to Cardiovascular Imaging and Anatomy
Explore a detailed collection of images showcasing cardiovascular imaging, radiological anatomy of the chest, vascular anatomy, and pulmonary conditions like embolism. Discover the gold standard for diagnosing pulmonary embolism, as well as CT angiograms and aortic arch anatomy. Engage with visuals
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Understanding Haemodynamic Consequences of Acute Pulmonary Embolism
Haemodynamic consequences of acute pulmonary embolism (PE) include increased mean pulmonary artery pressure, rise in right ventricular preload and end-diastolic pressure, risk of right ventricular failure, and decreased pulmonary blood flow leading to low systolic blood pressure. Arterial hypoxia ca
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Sudden Death and Pulmonary Embolism in a Forensic Medicine Case Study
A 57-year-old woman admitted for abdominal pain tragically dies from a pulmonary embolism after collapsing outside the hospital. This case study delves into the definition of sudden death, major causes within the respiratory organs, and predisposing factors like deep vein thrombosis. References incl
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Understanding Blood Clots, Vessel Blockage, and Strokes
Polymers, blood clots, vessel blockages, and strokes are explained in this informative content. Blood clot formation, vessel blockages due to embolism and thrombosis, and the different types of strokes are detailed. The effects of stroke on the brain and its various regions are highlighted.
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Understanding Atherosclerosis and Peripheral Artery Diseases
Atherosclerosis is a progressive process triggered by an inflammatory response, often aggravated by hypertension. Conditions like claudication and critical limb ischemia are indications of inadequate blood flow, posing risks of rest pain and ischemic ulcers. Recognizing symptoms like pain, numbness,
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