Age-Friendly App: Managing Drug-Drug Interactions Between Prescriptions and OTC Analgesics
The Age-Friendly app addresses the crucial issue of drug-drug interactions between current prescriptions and over-the-counter analgesics in the geriatric population. With a significant percentage of OTC sales attributed to older adults, there is an increased risk of adverse drug events due to polyph
1 views • 25 slides
Exploring TOLERANCE - Artwork by Guy Ferrer
Guy Ferrer, a contemporary French/Mediterranean artist, created the TOLERANCE series to address religious tensions and promote compassion, hope, and mutual respect. Through his sculptures, Ferrer advocates for universal tolerance, emphasizing the importance of accepting different beliefs to foster h
0 views • 16 slides
Understanding Regulatory Requirements of Drugs and Pharmaceuticals
Drug regulation involves controlling drug use through international agreement authorities like the FDA, EMA, and PMDA. The FDA plays a crucial role in drug evaluation and research, biologic evaluation, devices, and food safety. There are various types of applications for drug approval, along with a
0 views • 28 slides
Polymeric Controlled Drug Delivery Systems
Polymeric controlled drug delivery systems play a crucial role in regulating drug release through diffusion, solvent penetration, and chemical mechanisms. These systems include diffusion-controlled, solvent-controlled, and chemically-controlled devices, each operating based on specific principles. S
0 views • 33 slides
Renal Pharmacology: Drug Excretion and Renal Clearance Questions
This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID
0 views • 55 slides
Understanding Nasopulmonary Drug Delivery System
Nasopulmonary drug delivery system, utilizing the nasal route for drug administration, offers advantages such as hepatic first-pass metabolism avoidance and rapid drug absorption. This system is beneficial for pharmacologically active compounds with poor stability in gastrointestinal fluids. While i
0 views • 35 slides
Understanding Physicochemical Properties of Drugs
The physicochemical properties of drugs play a crucial role in their pharmacological effects. These properties include physical and chemical characteristics that influence interactions with biomolecules. Solubility, partition coefficient, and dissociation constant are key factors affecting drug beha
1 views • 46 slides
Understanding Formulary Systems in Healthcare
A formulary is a dynamic list of medications curated by healthcare professionals to guide drug selection based on efficacy, safety, cost, and patient acceptability. It plays a vital role in promoting evidence-based and cost-effective drug therapy, improving communication between prescribers and phar
0 views • 17 slides
Understanding Autoimmunity and Immunological Tolerance
Autoimmunity is a condition where the body's immune cells mistakenly attack its own tissues, leading to damage. Immunological tolerance helps prevent this by mechanisms like central and peripheral tolerance. Central tolerance involves deleting self-reactive immune cells during maturation in key orga
0 views • 32 slides
Ways to Stay Drug Free: Lessons for Teens and Families
Understanding the reasons behind drug usage among teens, this lesson provides valuable resources and strategies to stay drug-free. It emphasizes the importance of making healthy decisions and offers alternatives to drug use. Additionally, it highlights the significance of saying no to drugs, provide
0 views • 17 slides
Understanding the Hatch-Waxman Act: Promoting Affordable Generic Drugs
The Hatch-Waxman Act, also known as The Drug Price Competition and Patent Term Restoration Act, was enacted in 1984 to amend patent laws and the Federal Food, Drug, and Cosmetic Act. It aims to reduce costs associated with generic drug approval, allow early experimental use, compensate branded drug
0 views • 49 slides
Understanding Biopharmaceutics: pH Partition Theory and Drug Absorption
Biopharmaceutics explores how drug properties and administration methods impact drug absorption. Factors affecting oral absorption include membrane physiology and drug partitioning based on pH levels. The pH partition theory, explained by Brodie et al., highlights the role of drug lipid solubility a
0 views • 9 slides
Importance of In-Vitro Dissolution Testing in Drug Assessment
In drug development, in-vitro dissolution testing plays a crucial role in evaluating drug release from tablets when in-vivo bioavailability studies are limited. By ensuring drug release is close to 100% and uniform batch to batch, these tests help assess drug availability and effectiveness. Regulato
10 views • 10 slides
Understanding Pharmacodynamics: Potency and Efficacy
Pharmacodynamics explores how drugs interact with receptors in the body, affecting the magnitude of drug effects based on concentration. Graded dose-response relationships, potency, and efficacy play key roles in determining drug efficiency. Potency reflects the amount of drug needed for a specific
0 views • 21 slides
Understanding Drug Absorption, Excretion, and Bioavailability in Humans
Delve into the complex processes of drug absorption, excretion, and bioavailability in the human body. Learn about the various factors affecting drug absorption from the gastrointestinal tract, including biological, physiochemical, and pharmaceutical factors. Explore the mechanisms of drug transport
0 views • 24 slides
Understanding Quantitative Aspects of Drug Action
Explore the quantitative aspects of drug action, including drug receptor binding, concentration binding curves, dose-response curves, and types of antagonism. Learn to relate drug concentration to receptor binding capacity and response produced. Discover how concentration binding curves and dose-res
0 views • 29 slides
Review of DRE School and Drug Evaluation Techniques
Explore key topics such as the definition of drugs for DRE purposes, basic drug statistics, review of symptomatology, and vital signs assessment in the context of Drug Recognition Expert (DRE) training. Learn about CNS depressants, stimulants, hallucinogens, and analogs, as well as vital signs like
0 views • 29 slides
Study on Juvenile Drug Crime Prevention in Taiwan: Insights from ACS Conference 2020
This presentation at the Asian Criminological Society Conference 2020 delves into the current situation, dilemmas, and responses regarding juvenile drug crime prevention in Taiwan. The presenter, Zeng Li-Wen, a PhD student at Central Police University in Taiwan, provides valuable insights based on t
0 views • 20 slides
Understanding Drug Abuse: Definitions, Effects, and Stages
Drug abuse is a serious issue involving various substances like prescription drugs, alcohol, and illegal drugs. This includes terms and definitions, effects on the body and mind, stages of addiction, and withdrawal symptoms. Factors influencing drug action and reasons for drug use are also explored.
4 views • 45 slides
Understanding Drug Targets and Mechanisms of Action
Explore the intricate world of pharmacokinetics and pharmacodynamics, from drug absorption to their interaction with biological molecules. Learn about different drug targets, such as proteins and ions, and how drugs alter their biochemical and biophysical activities. Dive into molecular mechanisms o
3 views • 17 slides
International Day Against Drug Abuse and Illicit Trafficking 2022 Initiatives and Awareness
The United Nations observes 26th June as the International Day Against Drug Abuse and Illicit Trafficking to combat substance abuse worldwide. Various initiatives like the National Drug Master Plan, Nasha Mukt Bharat Abhiyaan, and the National Action Plan for Drug Demand Reduction aim to raise aware
3 views • 9 slides
Understanding Basic Hole and Shaft Systems in Manufacturing Processes
Basic Hole and Shaft Systems are essential procedures for determining mating part dimensions and tolerance information in manufacturing drawings. By knowing parameters such as Basic Size, Allowance, Hole Tolerance, and Shaft Tolerance, accurate and functional parts can be produced. This system ensur
0 views • 36 slides
Comprehensive Review of Drugs, Categories, and Drug Influence Evaluation
This mid-course review covers key aspects such as defining drugs, naming drug categories and subcategories, identifying drug categories for specific drugs, components of drug influence evaluation, and examinations conducted as part of the evaluation process. The content also includes identifying dru
0 views • 28 slides
Understanding RAID 5 Technology: Fault Tolerance and Degraded Mode
RAID 5 is a popular technology for managing multiple storage devices within a single array, providing fault tolerance through data striping and parity blocks. This article discusses the principles of fault tolerance in RAID 5, the calculation of parity blocks, handling degraded mode in case of disk
0 views • 12 slides
Understanding Religious Tolerance in Schools: Insights from Research
Exploring the levels of religious tolerance among students in different types of schools such as Roman Catholic, Evangelical Christian, Muslim, and Non-Faith institutions. The research considers factors influencing students' attitudes towards diversity and highlights varying levels of active toleran
0 views • 15 slides
Impact of Socioeconomic Conditions on Drug Use Disorders: Insights from World Drug Report 2020
The World Drug Report 2020 highlights the strong correlation between socioeconomic factors and drug use disorders. Studies reveal that communities facing poverty, violence, and social inequality are at a higher risk of drug overdoses and addiction. Factors like income inequality, lack of social capi
0 views • 17 slides
Exploring Zero Tolerance: Creating a Safe and Supportive Workplace
This session aims to delve into the concept of zero tolerance towards unacceptable behaviors such as bullying, harassment, assault, and abuse in the workplace. It discusses prevention, protection, response strategies, and feedback mechanisms to ensure a supportive and secure environment for all empl
0 views • 5 slides
Understanding Targeted Clinical Investigation in Pharmacovigilance
Targeted clinical investigation plays a crucial role in pharmacovigilance by further evaluating significant risks identified in pre-approval clinical trials. This involves conducting pharmacokinetic and pharmacodynamic studies, genetic testing, interaction studies, and large simplified trials to ass
0 views • 12 slides
Byzantine Fault Tolerance: Protocols, Forensics, and Research
Explore the realm of Byzantine fault tolerance through protocols like State Machine Replication and HotStuff, discussing safety, liveness, forensic support, and the impact of Byzantine faults. Dive into decades of research on achieving fault tolerance and examining forensic support in the face of By
0 views • 24 slides
Advancing Rice Breeding Partnerships in Myanmar: Current Progress and Future Prospects
The collaborative efforts between IRRI and Myanmar in rice breeding have been fruitful since 1965, with numerous rice varieties released in Myanmar having IRRI lineage. The focus is on developing appropriate rice varieties for different regions to ensure rice yield stability. Target traits for delta
1 views • 17 slides
Understanding Organizational Risk Appetite and Tolerance
Explore the development of market risk appetite goals and how to define and establish organizational risk tolerance. Learn about the Classic Simplified View of Risk Tolerance and different methods to determine risk appetite. Discover the importance of assessing market risk impact and aligning risk t
0 views • 8 slides
Advances in Ophthalmic Drug Delivery Systems
This content explores various advanced ophthalmic drug delivery systems including erodible ophthalmic inserts, soluble ocular drug inserts, new ophthalmic drug delivery systems, and bioadhesive ophthalmic drug inserts. These innovative systems aim to provide accurate dosing, prolonged drug release,
0 views • 8 slides
State Responsible Inmates with Marijuana Convictions Research Report
Research conducted by VADOC indicates a total of 570 state responsible inmates incarcerated for marijuana-related offenses as of August 31, 2021. Among them, 229 inmates had non-drug-related Most Serious Offenses, 331 were convicted for Drug Sales MSO, and 10 were convicted for Drug Possession MSO.
0 views • 7 slides
Innovative Online Learning for Drug Court Professionals
Center for Court Innovation has introduced a new National Drug Court Online Learning System aimed at assisting drug court professionals. This system offers free access to web-based training, expert video lessons, virtual site visits to drug treatment courts, practitioner interviews, and a resource l
0 views • 8 slides
Fault-Tolerant MapReduce-MPI for HPC Clusters: Enhancing Fault Tolerance in High-Performance Computing
This research discusses the design and implementation of FT-MRMPI for HPC clusters, focusing on fault tolerance and reliability in MapReduce applications. It addresses challenges, presents the fault tolerance model, and highlights the differences in fault tolerance between MapReduce and MPI. The stu
0 views • 25 slides
Understanding Drug Testing Policies in the Workplace
The Drug-Free Workplace Act of 1988 mandates federal grant recipients to implement zero-tolerance drug policies to maintain a drug-free environment. Employers must establish clear policies, conduct awareness programs, offer counseling and rehabilitation services, and impose penalties for violations.
0 views • 19 slides
Computing Tolerance Intervals in JMP: An Add-In for Efficient Data Analysis
Tolerance intervals play a crucial role in statistical analysis, especially in industries like pharmaceuticals. This article introduces an add-in in JMP for computing tolerance intervals, highlighting the significance of understanding and interpreting these intervals correctly. The tool aims to simp
0 views • 4 slides
Understanding the Effects of Air Gap Tolerance on Inductance Tolerance
This technical note delves into the impact of air gap tolerance on inductance tolerance in transformer manufacturing. It explains how controlling the core's air gap dimension is crucial for maintaining desired inductance levels within manufacturing constraints. The text discusses the small scale of
0 views • 10 slides
Low-Redundancy Proactive Fault Tolerance for Stream Machine Learning
This study focuses on enabling fault tolerance for stream machine learning through erasure coding. Fault tolerance is crucial in distributed environments due to worker failures, and existing approaches like reactive fault tolerance and proactive replication have drawbacks. The use of erasure coding
0 views • 20 slides
Understanding Azole Therapeutic Drug Monitoring for Antifungal Therapy
Azole therapeutic drug monitoring (TDM) is crucial for managing antifungal therapy due to factors like drug interactions, compliance issues, disease severity, and pharmacokinetic variability. This monitoring helps ensure optimal drug levels are maintained for effective treatment. Different TDM metho
0 views • 18 slides