Dna methylation epigenetics - PowerPoint PPT Presentation


Epigenetics Market Projected to Surpass $5.47 Billion in Value by 2030

Epigenetics Market by Offering (Kits, Reagents, Instruments, Software) Method (DNA Methylation, PCR, Chromatin Analysis, Histone, RNA Modification), Application (Oncology, Non-oncology) End User (Pharma, Academics, Hospitals) \u2013 Global Forecast to 2030\n

0 views • 4 slides


Understanding DNA Mutations and Their Types

DNA mutations are changes in the DNA molecule that can lead to permanent alterations in the base sequence of daughter DNA. Causes include uncorrected errors, as well as damage from oxidative deamination, radiation, and chemicals. The types of mutations include point mutations, insertion mutations, d

4 views • 7 slides



Comprehensive DNA Characterization Methods in Molecular Biology

Explore the various techniques involved in the characterization of DNA, including spectrophotometric assay, melting temperature determination, quantitative and qualitative analyses, DNA purity assessment, GC content calculation, and DNA denaturation processes. Learn how to determine DNA concentratio

0 views • 12 slides


Understanding DNA Extraction from Strawberries in Molecular Genetics

In this molecular genetics lesson, students explore DNA extraction from strawberries. The content covers the structure of DNA, nucleotides, and the role of DNA in determining genetic information. Students learn about the components of nucleic acids, DNA functions, and the double helix structure of d

0 views • 87 slides


Epigenetics in Biology: Exploring the Impact of Parental Diet on Offspring Traits

Explore the fascinating world of epigenetics in biology through a focused unit on how parental diet can influence offspring traits. Dive into learning goals, outcomes, and a detailed tidbit outline that includes activities and resources for understanding the molecular mechanisms behind these effects

0 views • 21 slides


Understanding the Structure and Importance of DNA

Explore the essential components and structure of DNA, including nucleotides, RNA, and the significance of DNA in carrying genetic information across generations. Learn about the four DNA nucleotides, how mononucleotides are formed, and the discovery of DNA's structure. Dive into base pairing and th

0 views • 30 slides


Understanding the Relationship Between DNA and Protein Specificity

The relationship between an organism's DNA and protein specificity is intricate. DNA encodes the information for the sequence of amino acids in proteins, thereby determining their specificity. This process involves DNA directing the synthesis of specific RNA molecules, which are then translated into

0 views • 17 slides


Understanding DNA Ligation Techniques for Molecular Biology Applications

DNA ligation involves joining DNA fragments to vectors to create new DNA or plasmids. Methods include DNA ligase, T4 ligase, and terminal deoxynucleotidyl transferase. Linkers and adaptors play a key role in DNA cloning experiments by generating sticky ends for DNA cloning. The use of adaptors allow

1 views • 13 slides


Understanding DNA Replication in Prokaryotes for B.Sc. Botany Hons. Students

Study material on DNA replication in prokaryotes focusing on key concepts like semiconservative mode of replication, involvement of enzymes, different models for understanding replication, and the bidirectional nature of DNA replication in prokaryotes. The material covers the process steps including

0 views • 33 slides


Understanding Epigenetics: DNA Methylation and Histone Modification

Epigenetics involves modifications that impact gene expression without altering DNA sequences, playing a crucial role in the transition from genotype to phenotype. This includes DNA methylation, histone modification, and microRNAs. DNA methylation, controlled by DNMT enzymes, can lead to either gene

5 views • 12 slides


Lab 2: DNA Extraction Techniques for Arthropods and Wolbachia

In this lab activity, students will learn how to isolate genomic DNA from arthropods and Wolbachia bacteria. The goal is to transition from fieldwork to molecular biology, utilizing DNA as a diagnostic tool. The activity involves extracting total genomic DNA from identified species and includes pre-

0 views • 11 slides


Introduction to Phage DNA Integration in Bacterial Cells

Phage DNA can be introduced into bacterial cells through two methods: transfection and in vitro packaging. Transfection involves mixing purified phage DNA with competent E. coli cells, inducing DNA uptake via heat shock. In vitro packaging utilizes proteins coded by the phage genome, which can be pr

1 views • 13 slides


Pulsed-Field Gel Electrophoresis: Separating Large DNA Molecules

Pulsed-Field Gel Electrophoresis (PFGE) is a technique developed to effectively separate large DNA molecules through the application of an electric field that periodically changes direction. This method, introduced by David C. Schwartz and Charles C. Cantor in 1984, revolutionized the resolution of

1 views • 11 slides


Understanding Epigenetics: DNA Methylation and Histone Modification

Epigenetics refers to changes in gene expression without altering the DNA sequence. This involves processes like DNA methylation, histone modification, and microRNAs. DNA methylation is controlled by DNA methyltransferase enzymes and plays crucial roles in gene activation and silencing. Histone modi

0 views • 13 slides


Understanding DNA Profiling: Techniques and Applications

DNA profiling, invented by Alec Jeffreys in 1985, is a technique used to distinguish between individuals of the same species based on their DNA. The process involves breaking down cells to release DNA, cutting the DNA into fragments using restriction enzymes, separating and analyzing fragments based

12 views • 23 slides


Strategies for Differential Methylation Analysis in Epigenetics Research

Explore the process of differential methylation analysis through raw data handling, statistical power assessment, and correction considerations. Learn how to identify significant changes in methylation levels and address challenges like global differences and statistical power in epigenetic research

0 views • 33 slides


Understanding DNA, Chromosomes, and Chromatin Structure

DNA is made up of genes, chromosomes, and chromatin. Genes carry vital information for protein synthesis, while chromosomes are condensed DNA required for cell division. Junk DNA are non-coding regions, and sister chromatids are identical DNA copies. Homologous chromosomes have matching structures,

1 views • 17 slides


Understanding the Epigenetic Clock and Ageing Factors

Explore the Epigenetic Clock model used to estimate biological age in mice by analyzing DNA methylation changes. Learn about the difference between chronological and biological age, the influence of epigenetics on ageing, and how lifestyle factors like diet, fat content, caloric intake, and growth h

0 views • 10 slides


Understanding Recombinant DNA and Gene Cloning

Recombinant DNA is artificially created by combining DNA from multiple sources into a single molecule. This process involves treating DNA with restriction endonucleases, such as BamHI, which cut at specific sites, resulting in sticky ends that can base pair with complementary DNA molecules. DNA liga

0 views • 33 slides


Understanding DNA Methylation and Cadmium Exposure in Utero: An Epigenetic Analysis

Explore the complex relationship between DNA methylation and in utero exposure to cadmium through a set of informative slides created by Dana Haine, MS. Learn about the impacts of DNA methylation on gene expression and how changes in methylation levels can lead to gene silencing or activation. Disco

0 views • 8 slides


Understanding Sanger DNA Sequencing Procedure

Overview of Sanger (dideoxy) DNA sequencing, involving deoxynucleotides and dye-labeled dideoxynucleotides to image DNA band sizes. The simulation model includes steps like denaturing DNA, annealing primers, and synthesizing DNA chains using dNTPs and ddNTPs. The process culminates in electrophoresi

0 views • 7 slides


Epigenetics Market

The Epigenetics Market is forecasted to grow to $6.33 billion by 2031, with a projected CAGR of 15.7% over the period from 2024 to 2031.\n

0 views • 4 slides


Overview of Thermostable DNA Polymerases and Their Properties

Thermostable DNA polymerases play a crucial role in various molecular biology techniques, with Taq DNA polymerase being a household name due to its discovery in Thermus aquaticus. These enzymes catalyze DNA synthesis, require magnesium ions for activity, and exhibit optimal function at high temperat

0 views • 8 slides


Understanding DNA Transformation in Bacterial Cells

DNA transformation is a crucial process in genetic engineering, where foreign DNA is introduced into bacterial cells such as E. coli. This process, known as transformation, involves making the cells competent to uptake DNA through physical and chemical treatments. The uptake of DNA occurs after trea

0 views • 34 slides


Understanding DNA Structure: A Comprehensive Overview

DNA, or deoxyribonucleic acid, is a fundamental molecule in genetics. It consists of two antiparallel polynucleotide chains made up of monomer units containing sugars, phosphates, and nitrogenous bases. The structure of DNA includes deoxyribose sugar, phosphate groups, and nitrogenous bases like ade

0 views • 18 slides


Understanding DNA Replication Process in Living Organisms

DNA replication is a fundamental biological process where an original DNA molecule produces two identical copies. This process involves initiation, elongation, and termination stages, utilizing replicator and initiator proteins. The DNA is unwound and replicated with the help of enzymes like helicas

0 views • 16 slides


Understanding DNA in Forensic Science: Solving Crimes with Evidence

DNA, or deoxyribonucleic acid, plays a crucial role in solving crimes by providing unique genetic information that can link suspects to evidence, identify victims, and link crime scenes. Factors such as environmental conditions can influence the reliability of DNA evidence. CODIS, the Combined DNA I

0 views • 8 slides


DNA Extraction from Blood: Methods and Protocol

Studying DNA is crucial for disease prevention, diagnosis, and treatment. This guide provides a step-by-step protocol for extracting DNA from blood, involving procedures like cell lysis, protein and RNA removal, DNA precipitation, and final nucleic acid determination. Key steps include using reagent

0 views • 6 slides


Understanding DNA and Genetics: A Comprehensive Overview

Living things store, retrieve, transmit, and respond to information essential for life processes. This encompasses the heritability of genetic traits through DNA and RNA, the discovery of the double helix structure of DNA, and key experiments validating DNA as the heritable molecule. Explore the com

0 views • 30 slides


Visualising and Exploring BS-Seq Data: Tips and Insights

Explore essential strategies for analysing BS-Seq data, ranging from selecting appropriate methylation contexts to identifying coverage outliers and biases. Understand how to interpret data patterns, handle unusual findings, and mitigate potential errors, ensuring accurate methylation analysis resul

0 views • 40 slides


Advancing Multi-Omics Research with Integrated Methods

Exploring the importance of multi-variate methods in multi-omics research to integrate diverse datasets such as phenotypes, metabolites, expression, methylation, and SNPs. The overview covers matrix-based methods, sparse methods for feature selection, and an example analysis from the MESA Multi-Omic

0 views • 17 slides


Understanding DNA Structure, Replication, and Proofreading

Exploring the intricate world of DNA, this module delves into the structure of DNA, highlighting nucleotides, nitrogenous bases, and the double helix. It emphasizes how DNA stores genetic information in genes and undergoes replication through a semi-conservative model. The process of DNA replication

0 views • 13 slides


Epigenetics Market

The Epigenetics Market is expected to grow at a CAGR of 15.7% from 2024 to 2031, reaching a projected value of $6.33 billion by 2031.\n

0 views • 4 slides


Epigenetics Market

By 2031, the Epigenetics Market is projected to attain a value of $6.33 billion, growing at a CAGR of 15.7% throughout the forecast period from 2024 to 2031.\n

0 views • 3 slides


Understanding DNA Fingerprinting and Its Applications

DNA fingerprinting, also known as DNA profiling, is a crucial technique used in forensic labs for identifying suspects or determining paternity. By cutting DNA with restriction enzymes and using gel electrophoresis, DNA fragments are separated according to size to create unique profiles. This highly

0 views • 20 slides


Understanding Different Forms of DNA Structures

DNA can exist in various forms such as single-stranded, double-stranded, and mixed forms. The primary, secondary, and tertiary/quaternary structures play crucial roles in determining the overall structure of DNA. Forms like A-DNA and B-DNA have distinct characteristics and are commonly found in diff

0 views • 57 slides


SeqMonk Tools for Methylation Analysis Overview

Explore the features and functionalities of SeqMonk for methylation analysis, including data model, raw data visualization, movement controls, quantitation models, probe generation, and targeting measurement methods.

0 views • 20 slides


Understanding DNA and DNA Replication: Key Concepts with Visual Aids

Explore essential terms related to DNA and DNA replication, including chromosomes, genes, nucleotides, double helix structure, hydrogen bonds, and more. Discover the process of DNA replication, involving enzymes like DNA polymerase and helicase, and the concept of semi-conservative replication. Rein

0 views • 13 slides


Epigenetic Impact of Prenatal Famine Exposure on Growth and Metabolism

DNA methylation signatures have been identified linking prenatal famine exposure to altered growth and metabolism. The Dutch Hunger Winter of 1944-1945 serves as a key reference point, showing associations with higher BMI, cholesterol levels, and increased risk of schizophrenia. Reduced Representati

0 views • 22 slides


Insights into DNA Replication and Chromosome Structure

DNA replication is a fundamental process vital for the transmission of genetic information. Chromosomes, composed of DNA-protein complexes, store genetic information, and replication involves the synthesis of new DNA molecules. Enzymes play crucial roles in DNA synthesis, and in E. coli cells, repli

0 views • 16 slides