Acute pulmonary embolism (PE) is a significant issue in hospitalized patients, with current treatments focusing on anticoagulation and systemic thrombolysis. Surgical treatments have shown poor outcomes, leading to a rise in endovascular techniques aimed at reducing clot burden. A survey conducted i

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The Bleeding Time (BT) test evaluates platelet plug formation and capillary integrity, crucial for surgery preparations. Prolonged bleeding times indicate low platelet count or dysfunction. The Duke method is one way to determine Bleeding Time. Sources of error, such as medication interference, impr

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Blood clotting factors play a crucial role in the coagulation process to prevent excessive bleeding. Factors such as Fibrinogen (Factor-I), Prothrombin (Factor-II), Thromboplastin (Factor-III), Calcium Ions (Factor-IV), Labile Factor (Factor-V), and Stable Factor (Factor-VII) are essential for the c

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Explore the essential information about Continuous Bladder Irrigation (CBI), including its procedure, indications, supplies and equipment needed, documentation guidelines, and monitoring protocols. Learn about the importance of CBI in post-prostate surgery, urinary tract obstruction prevention, clot

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Venous thromboembolism occurs when a blood clot forms in a vein, obstructing the blood flow and posing a potentially life-threatening risk. Several devices and drugs are employed for the prevention and treatment of venous thromboembolism. The devices considered within this scope are utilized for bot

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Dr. Linzy Elton, a postdoctoral research associate at the Centre for Clinical Microbiology, explores the importance of extracting high-quality TB DNA for sequencing. The workshop delves into the challenges of extracting DNA from TB due to its complicated cell wall and outlines the biological safety

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Filamentous coliphages M13, f1, and fd are utilized as cloning vectors due to their circular single-stranded DNA molecules and advantages over other vectors. These phages have dimensions of 900 nm x 9 nm and infect bacteria through F pili, releasing up to 1000 phage particles per cell per generation

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Mrs. Sashmitha Samuel, an Associate Professor in the Department of Pharmaceutical Chemistry, delves into the importance of coagulants, anti-coagulants, and the components of blood. Blood, a vital fluid in the body, carries nutrients, oxygen, and helps remove waste products. Learn about the process o

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Hemostasis, crucial for preventing blood loss, involves platelet formation, clotting factors, and fibrinolysis. This process includes vessel constriction, platelet activation, clot formation, and fibrin breakdown. Platelets, produced in the bone marrow, play a vital role in maintaining vascular inte

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Thrombolytic therapy involves the use of drugs to dissolve blood clots, with plasminogen activation being a key mechanism. Different types of thrombolytic drugs like fibrin-specific and non-fibrin-specific agents are available, each with varying effects on clot dissolution and systemic plasminogen a

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Coagulation is a crucial process in hemostasis that involves clot formation. This profile delves into estimating clotting time, bleeding time, and prothrombin time to assess coagulation status. Explore the mechanisms of hemostasis, clotting cascade, triggers of intrinsic and extrinsic pathways, and

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Inflammatory diseases of bone encompass conditions like osteitis, osteomyelitis, periostitis, and alveolar osteitis (dry socket). Osteitis is localized and may be associated with infected sockets, while osteomyelitis involves the interior of the bone. Alveolar osteitis commonly follows tooth extract

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Anticoagulants are crucial additives that prevent blood clotting during laboratory procedures. The commonly used anticoagulants include EDTA, sodium citrate, and heparin, each with specific concentrations, modes of action, and color-coded identifications. EDTA is ideal for blood cell counts, sodium

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Periodontal therapeutic modalities focus on root surface modifications due to periodontitis, which involves physical, chemical, and cytotoxic changes. Successful outcomes depend on factors like clot stability, cell migration, attachment, proliferation, and debridement. Analyzing cementum properties

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Hemostasis is crucial in neurosurgery for controlling bleeding without ligatures. Various topical hemostats like chemical, mechanical, collagen, thrombin, and fibrin glues are used. Surgicel and Oxycel, oxidized cellulose polymers, act as physical matrices aiding in clot formation. Gelatin sponges l

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The recombinant vector with a kanamycin resistance gene can be used to clone other genes by inserting human DNA fragments and selecting transformed E. coli cells. This technique has enabled the production of various human proteins for therapeutic purposes, such as insulin, growth hormones, and clot-

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DNA extraction is a crucial process in molecular biology that involves separating DNA from cellular components. The process includes steps like lysis, precipitation, and purification to obtain pure DNA samples. Careful handling and proper labeling of samples are essential to prevent contamination. T

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Studying DNA is crucial for disease prevention, diagnosis, and treatment. This guide provides a step-by-step protocol for extracting DNA from blood, involving procedures like cell lysis, protein and RNA removal, DNA precipitation, and final nucleic acid determination. Key steps include using reagent

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This informative content by Dr. Michael Zappitelli from Montreal Children's Hospital discusses the prescription rates, doses, and fluids involved in Pediatric CRRT. It covers insights on blood flow rates, diverse solutions used, and ideal compositions for Peritoneal dialysis fluid. The article empha

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Polymers, blood clots, vessel blockages, and strokes are explained in this informative content. Blood clot formation, vessel blockages due to embolism and thrombosis, and the different types of strokes are detailed. The effects of stroke on the brain and its various regions are highlighted.

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The clotting cascade is a complex process involving intrinsic and extrinsic pathways that converge to form fibrin, leading to clot formation. Hemostasis is initiated mainly through the extrinsic pathway in vivo, activating factors that generate thrombin and ultimately convert fibrinogen into insolub

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