Understand the correlation between lipoprotein metabolism imbalance and the development of atherosclerosis. Learn about LDL and HDL cholesterol metabolism, receptor-mediated endocytosis, and the role of lipoprotein(a).

1 views • 19 slides

Pharmacokinetics, as explained in a lecture by Oula Mohammed Sami, M.B.Ch.B/MSc in clinical pharmacology, delves into how the body processes drugs, contrasting with pharmacodynamics which focuses on drug actions. Key topics covered include properties influencing treatment outcomes, the significance

5 views • 45 slides

Exploring the genetic control of metabolism in microbes, focusing on wild type organisms and the process of strain improvement through mutagenesis, selective breeding, and recombinant DNA techniques. The potential benefits and challenges of altering microbial genomes for biotechnological application

0 views • 27 slides

Cellular respiration is a vital process in all living cells, producing energy through chemical reactions. Metabolism, consisting of anabolism and catabolism, maintains growth and function. ATP plays a central role as energy currency in cells. Through stages like glycolysis and the Krebs cycle, cellu

0 views • 16 slides

Digestion and metabolism of protein in both ruminants and non-ruminants involve enzymatic breakdown of proteins into polypeptides and amino acids in the stomach and intestines. Key enzymes such as pepsin, trypsin, and chymotrypsin play important roles in protein digestion. Gastric digestion in the s

1 views • 14 slides

Calcium metabolism plays a critical role in various bodily functions like nerve conduction, coagulation, and bone mineralization. It involves processes such as calcium absorption, distribution, and homeostasis, regulated by hormones like PTH and calcitriol. The balance of calcium in the body is cruc

7 views • 50 slides

Paracetamol, a widely used non-opioid analgesic, is effective for treating musculoskeletal pains and headaches. This synthetic medication primarily acts in the Central Nervous System and is available in various forms. However, caution is advised due to potential side effects such as rare skin reacti

0 views • 31 slides

Explore the detailed information about bilirubin metabolism and various types of jaundice, including their clinical presentations, etiologies, and management strategies. Learn to differentiate between different types of jaundice based on case scenarios and understand the functional anatomy and physi

0 views • 33 slides

Nitrogen metabolism is crucial in the biosynthesis of amino acids such as glutamate and glutamine, incorporating ammonia for various physiological processes. Ammonia is efficiently transported and stored using compounds like alanine and glutamate, playing a key role in the urea cycle. Glutamate, a v

0 views • 22 slides

Metabolism of xenobiotics, foreign chemicals like drugs, food additives, and pollutants, is crucial for pharmacology, toxicology, and disease management. Knowledge allows for beneficial applications such as antioxidant research, pollutant conversion, and drug biosynthesis using transgenic organisms.

0 views • 11 slides

Exploring the metabolic processes in seeds, this study aims to compare carbon dioxide production before and during germination. Students will hypothesize and verify using a carbon dioxide SensorLab sensor. Theoretical aspects of plant metabolism, including photosynthesis and cellular respiration, wi

1 views • 22 slides

The integration of metabolism involving carbohydrates, lipids, and proteins can be divided into three stages: hydrolysis to simpler units, preparatory stage, and oxidative stage. In the hydrolysis stage, complex polysaccharides, lipids, and proteins are broken down to simpler forms. The preparatory

2 views • 13 slides

Corticosteroids, including glucocorticoids and mineralocorticoids, play vital roles in intermediary metabolism, immune responses, and inflammation regulation. They bind to specific receptors in the cell, entering the nucleus to influence gene transcription and protein production. These hormones have

14 views • 32 slides

The process of protein digestion involves proteolytic enzymes produced by the stomach, pancreas, and small intestine. Pepsinogen is activated to pepsin in the stomach, breaking down proteins into oligopeptides and amino acids. After absorption, amino acids are utilized for protein synthesis and as d

0 views • 7 slides

Glycine, the simplest amino acid, plays a crucial role in various metabolic pathways in the body. It can be converted to important compounds like pyruvic acid, lactic acid, and creates the one-carbon pool. Glycine is essential for heme synthesis, glutathione formation, purine synthesis, and more. In

8 views • 19 slides

Inborn Errors of Metabolism (IEM) are genetic disorders that disrupt metabolic pathways, leading to substrate accumulation or product deficiency. These disorders can be classified based on toxic accumulation, protein metabolism, carbohydrate intolerance, lysosomal storage issues, energy production d

0 views • 29 slides

Amino acid metabolism involves pathways such as transamination, deamination, and the clinical significance of serum transaminases like ALT and AST. Transamination involves the transfer of amino groups, while deamination involves the removal of the amino group. Transaminases are important intracellul

0 views • 23 slides

Decarboxylation is a crucial reaction in amino acid metabolism where CO2 is removed to form biogenic amines, catalyzed by decarboxylase enzymes. Important biogenic amines include tyramine, tryptamine, and histamine, each impacting physiological functions like blood pressure regulation. Aromatic amin

0 views • 25 slides

Thyroid hormones, including triiodothyronine (T3) and thyroxine (T4), are essential for regulating metabolism, growth, development, body temperature, and heart rate. They are tyrosine-based hormones produced by the thyroid gland, requiring iodine for synthesis. T3 affects various physiological proce

2 views • 17 slides

The adrenal gland consists of the cortex and the medulla, each responsible for secreting different hormones. The cortex produces glucocorticoids, mineralocorticoids, and adrenal androgens, while the medulla secretes catecholamines. Corticosteroids play a crucial role in regulating metabolism, stress

0 views • 18 slides

Explore the intricate processes of oxidative decarboxylation and the Krebs Cycle, essential pathways in cellular energy metabolism. Learn about the conversion of pyruvate to acetyl-CoA, regulatory mechanisms, clinical implications, and more. Discover the fates of pyruvate, allosteric regulation, and

6 views • 19 slides

This article highlights the digestion and metabolism of fat in both ruminant and non-ruminant species. It explains the differences in lipid digestion in the stomach and small intestine of animals, focusing on the role of lipase, bile, and colipase in the breakdown of triglycerides. The process of mi

2 views • 19 slides

Carbohydrates play a vital role in energy production through processes like glycolysis and gluconeogenesis. Glucose metabolism involves pathways like aerobic glycolysis and anaerobic lactate production. In diabetes mellitus, there is a disruption in carbohydrate metabolism leading to elevated blood

1 views • 14 slides

Digestion and absorption of carbohydrates play a crucial role in the overall metabolism of ruminants and non-ruminants. This process involves various enzymes like amylase, maltase, lactase, and sucrase that break down complex carbohydrates into simpler forms for absorption in the small intestine. Ru

0 views • 17 slides

Exploring the multidimensional optimality of microbial metabolism through metabolic network analysis, C-based flux analysis, and stoichiometric reaction modeling. The concept of Pareto optimal solutions in multi-objective optimization problems is discussed in the context of microbial metabolic pathw

0 views • 22 slides

Exploring key factors influencing human comfort in energy management, including metabolism, migration, heat flow mechanisms, and the role of clothing. Metabolism impacts perception of thermal comfort, while migration helps regulate core temperature. Heat flow mechanisms like convection, conduction,

0 views • 26 slides

Exploring the intersection of genetic engineering and microbial community engineering to enhance electron bifurcation systems. Addressing trade-offs between synthetic biology and wildtype organisms, incorporating microbial community engineering in Synbio, and investigating CO2 metabolism in the abse

0 views • 8 slides

Exploring the fundamentals of biology and chemistry, including methods for problem-solving, characteristics of life, organic compounds in organisms, and the role of enzymes in metabolism. Learn about cellular organization, reproduction, metabolism, homeostasis, heredity, response to stimuli, growth

0 views • 21 slides

Explore the world of inborn errors of amino acid metabolism through lectures by Dr. Sumbul Fatma. Discover conditions like Phenylketonuria (PKU), Maple Syrup Urine Disease, Albinism, and more, caused by enzyme deficiencies due to gene mutations. Learn about classical PKU, hyperphenylalaninemia, and

0 views • 25 slides

This lecture discusses the various amino acidopathies, including phenylketonuria, albinism, alkaptonuria, maple syrup urine disease, and homocystinuria. It covers the metabolic defects in amino acid metabolism, symptoms, causes, and treatment methods for these disorders. Emphasizing the importance o

0 views • 19 slides

Explore the intricate control of erythropoiesis, iron metabolism, and hemoglobin synthesis in the body. Delve into the role of erythropoietin, factors influencing erythropoiesis rate, essential nutrients like iron and vitamins, and clinical conditions associated with anomalies in these processes. Ga

0 views • 25 slides

Explore the concept of metabolism through the roles of enzymes and ATP. Learn about chemical reactions in living cells, substrate interactions, and the essential functions of Adenosine Triphosphate. Test your knowledge with interactive quizzes and uncover the key principles governing cellular proces

0 views • 50 slides

The Pentose Phosphate Pathway, also known as the Hexose Monophosphate shunt, is an alternative route for glucose metabolism that plays a crucial role in NADPH synthesis, fatty acid production, antioxidant activity, and nucleotide formation. This pathway involves oxidative and non-oxidative phases, r

0 views • 12 slides

This content delves into the physiological and biochemical aspects of cortisol, diagnostic algorithms for Cushing's syndrome, and the interpretation of laboratory and radiological investigations for diagnosis. Explore the adrenal gland's anatomical features, the HPA axis, and glucocorticoid function

0 views • 16 slides

This content discusses the difference between background/endogenous and exogenous methanol, how metabolism of endogenous methanol affects exogenous metabolism, and the impact of exposure to different levels of methanol on blood concentrations. It highlights EPA PBPK models and assumptions regarding

0 views • 16 slides

Bilirubin, a key pigment in bile, is derived from heme breakdown and plays a crucial role in the liver's detoxification process. This article explores the metabolism of bilirubin, its relationship with heme and globin, as well as its excretion steps involving enzymatic reactions and conjugation in h

0 views • 31 slides

Drug metabolism is a crucial process in the body that transforms drugs into forms easily excreted, affecting their efficacy and toxicity. This involves different sites such as the liver, kidney, and plasma, with enzymes in cellular organelles like cytoplasm and mitochondria playing key roles. First-

0 views • 13 slides

Drug metabolism involves the biotransformation of pharmaceutical substances in the body, primarily in the liver, to facilitate their elimination. This process helps convert drugs into less active forms for enhanced elimination through various reactions in Phase I and Phase II metabolism. Factors suc

0 views • 20 slides

This presentation covers the functions of calcium, calcium metabolism, bone physiology, and hormonal regulation of calcium metabolism focusing on parathyroid hormone, calcitonin, and Vitamin D. It discusses hypo and hyperparathyroidism in detail, including clinical manifestations and treatment optio

0 views • 15 slides

Chronic angina is a condition marked by impaired quality of life and decreased life expectancy, primarily due to myocardial ischemia. It is characterized by symptoms like tightness, heaviness, and pressure sensation, often located retrosternally. The pathophysiology involves a mismatch between oxyge

0 views • 73 slides