Peripheral Arterial Disease (PAD), a condition caused by reduced blood flow in the legs or arms. Understand the symptoms, signs, importance of early detection, and who is at risk. Find out about the tests for PAD.

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Consultant Nephrologist Paraskevi Liaveri discusses the association between SGLT-2 inhibitors and acute kidney injury (AKI). Pharmacovigilance reports highlight a higher risk of AKI with these drugs, especially when combined with RAAS blockers, diuretics, or NSAIDs. Studies suggest potential mechani

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Echocardiographic assessment plays a crucial role in the diagnosis, management, and prognostic evaluation of pulmonary arterial hypertension (PAH). This condition is characterized by elevated mean pulmonary arterial pressure and pulmonary vascular resistance, leading to various clinical features suc

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Coronary Artery Bypass Graft (CABG) is a surgical procedure where a blood vessel from another part of the body is grafted onto an occluded coronary artery to bypass blockages. This procedure is less common in women compared to men and is typically indicated for severe coronary artery disease. It is

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This UK-wide clinical trial aims to assess the effectiveness of early peripheral norepinephrine infusion in adult patients with septic shock. The study will compare the impact on mortality and other outcomes of targeting a mean arterial pressure (MAP) above 65mmHg within the first 48 hours of admiss

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The AMPK system plays a crucial role in regulating energy homeostasis by sensing the cellular AMP:ATP ratio and responding to metabolic stresses that affect ATP production or consumption. AMPK is activated by factors such as hypoxia, glucose deprivation, and metabolic inhibitors, as well as by compo

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Conducting a thorough respiratory assessment is crucial in detecting early signs of deterioration in patients. This guide covers the key aspects of respiratory assessment, including assessing breathing, identifying different types of hypoxia, indications for assessment, pulse oximetry, visual and ta

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The brain receives its blood supply from four major arteries - two vertebral arteries and two internal carotid arteries. The vertebral arteries branch into the basilar artery, which gives rise to various important branches. The internal carotid arteries supply the anterior and middle cerebral arteri

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The article discusses the physiological basis, types, pathogenesis, and genetic predisposition of hypertension. It explains the revision of terminology related to blood pressure and the calculation of mean arterial pressure. Secondary hypertension, causes, and mean arterial pressure determination ar

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Shock is a state of low tissue perfusion leading to metabolic changes like anaerobic metabolism and acidosis. As cellular hypoxia progresses, immune and coagulation responses are activated, impacting cardiovascular, respiratory, renal, and endocrine systems. Shock can be classified into hypovolaemic

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Explore the intricate details of coronary circulation, including arterial supply, branches of coronary arteries, and areas of distribution. Dr. Abeer Al-Masri, an Associate Professor and Cardiovascular Physiologist at the Faculty of Medicine, KSU, provides valuable insights on the topic, covering th

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A term male baby born with perinatal hypoxia developed neonatal meningitis with convulsions. Blood culture revealed Acinetobacter sp. and Pseudomonas sp. Empirical antibiotic therapy was escalated to Colistin and Ceftazidime due to resistance. Subsequent testing showed colonies resembling Pseudomona

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In this detailed presentation by Dr. Sushma Tomar, Associate Professor of Anatomy, the intrinsic muscles of the tongue are explored, along with their functions, arterial and venous supply, lymphatic drainage, and nerve supply. The lecture covers the four intrinsic muscles in each half of the tongue,

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The cardiac cycle, involving systole and diastole processes, consists of arterial and ventricular events essential for heart function. Arterial events include systole and diastole, while ventricular events encompass isometric contraction, ejection period, prodiastole, isometric relaxation, rapid fil

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Oxygen therapy is a crucial intervention in veterinary medicine, especially in emergency situations to address hypoxia and increase oxygen delivery to tissues. It involves delivering high concentrations of oxygen to optimize oxygen levels in the blood. Indications for oxygen therapy include hypoxia

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Understanding the impact of high altitudes on human physiology is crucial for aviation and deep-sea activities. Barometric pressures and alveolar oxygen levels change significantly with altitude, leading to hypoxia-related issues. Factors like carbon dioxide and water vapor further affect alveolar o

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Rudolph Virchow's concept of disease starting at the cellular level highlights how cells constantly face challenges in maintaining homeostasis. The plasma membrane acts as a barrier against external stressors, but when cells face excessive physiological stresses or pathological stimuli, they adapt o

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The study discusses strategies to limit speeding opportunities on arterial streets, particularly focusing on the impact of traffic signal coordination on reducing speeding incidents. Results from simulation tests and real-world observations are presented, highlighting the effectiveness of signal con

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Explore essential terms like alveoli, perfusion, atelectasis, and more in the context of respiratory system function. Learn about lung anatomy, oxygenation processes, and common respiratory disorders like dyspnea and hypoxia. Discover the crucial factors for maintaining normal respiratory function.

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Peripheral Arterial Disease (PAD) refers to the narrowing of blood vessels outside the heart and brain, leading to reduced blood flow. This condition can result from atherosclerosis, inflammation, embolism, or thrombus formation. Learn about the causes, symptoms, diagnosis, and treatment strategies

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Reversing ocean hypoxia requires a paradigm shift towards cyclic nutrient use, increased efficiency in fertilizer use, and enhanced nutrient recovery from waste. The socioeconomic impacts of excess nutrients on marine ecosystems are substantial, highlighting the need for new partnerships and technol

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Climate impacts on the U.S. West Coast, including marine heat waves, species range shifts, hypoxia, ocean acidification, harmful algal blooms, sea level rise, and coastal erosion. Insights from experts like Jan Newton, NANOOS Director, highlight the significance of monitoring and addressing these en

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The cardiovascular system includes the heart, arteries, veins, and capillaries, responsible for the transport of blood and lymph throughout the body. Arterial blood vessels are classified based on diameter into large (elastic) arteries, medium (muscular) arteries, and arterioles. The arterial wall c

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Meconium Aspiration Syndrome (MAS) is a condition where a newborn aspirates meconium, the first substance discharged from the GI tract. This primarily affects term or post-term infants and can lead to airway obstruction, gas trapping, chemical pneumonitis, and PPHN. Risk factors include hypoxia and

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Cell injury can result from multiple stressors such as hypoxia, physical agents, chemicals, microbes, immunologic factors, nutritional imbalances, and aging. This can lead to reversible changes (degeneration) or irreversible changes (necrosis). Types of degeneration include cloudy swelling, hydropic

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Rudolph Virchow's concept of disease starting at the cellular level is explored in this content, focusing on the impact of the external environment on cell equilibrium. The role of the plasma membrane as a barrier and the definitions of normal cell function, adaptation, reversible injury, irreversib

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Gulf Restoration Network Decision, sources of Nutrients Nitrogen (N) and Phosphorus (P), impacts of Nutrient Pollution leading to Algae Blooms and Gulf Hypoxia (Dead Zone), measures to reduce Non-Point Source (NPS) contamination, EPA's current strategy, and Iowa's approach with its Nutrient Reductio

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Arterial blood gases (ABG) are obtained from arteries to assess acid-base balance and blood oxygen levels. The pH, PaCO2, PaO2, HCO3, and SaO2 are crucial values on an ABG report. These values reflect the blood's acid-base status, carbon dioxide levels, oxygen saturation, and more. The buffer system

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Chronic pulmonary emphysema is a complex obstructive and destructive lung condition typically caused by smoking. It leads to chronic infection, excessive mucus production, airway obstruction, and lung tissue destruction. The physiological effects of emphysema include hypoxia, hypercapnia, and severe

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In a case of postoperative hypotension following a transurethral prostatectomy under spinal anesthesia, a 78-year-old patient presented with agitation and shivering in the PACU. Vital signs and pain scores were monitored, showing a blood pressure of 89/40, heart rate of 85/min, and respiratory rate

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Oxygen, a vital nonmetallic element, plays a crucial role in various processes essential for living organisms. It is involved in energy production, metabolism, immune system support, and more. However, the lack of oxygen can lead to serious conditions like hypoxia. Learn about the uses, effects, and

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Shock, a state of systemic hypotension resulting in impaired tissue perfusion and cellular hypoxia, has various types such as cardiogenic, hypovolemic, septic, neurogenic, and anaphylactic shock. Each type has different mechanisms and causes, leading to decreased cardiac output and multiorgan failur

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Haemodynamic consequences of acute pulmonary embolism (PE) include increased mean pulmonary artery pressure, rise in right ventricular preload and end-diastolic pressure, risk of right ventricular failure, and decreased pulmonary blood flow leading to low systolic blood pressure. Arterial hypoxia ca

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Pulmonary Arterial Hypertension (PAH) is a progressive disease characterized by increased blood pressure in the pulmonary artery, veins, or capillaries. This condition can lead to right ventricular failure and eventual death if left untreated. PAH can have various causes, including idiopathic factor

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The Oregon Conservation and Recreation Fund Advisory Committee held a virtual meeting on January 10th, 2024. The agenda included reviewing and approving meeting minutes, a guest presentation on ocean acidification, hypoxia, budgeting, and RFP determinations for 2024. Lessons learned from past OCRF s

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Screening, enrollment, and inclusion/exclusion criteria insights for the Brain Oxygen Optimization in Severe Traumatic Brain Injury (TBI) Phase 3 Protocol are discussed. Key points include handling urgent patient queries, guidelines on hypotension and hypoxia, pupil assessment considerations, and su

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Oxygen therapy is a crucial medical intervention for various conditions, such as hypoxia, impaired gas exchange, and heart failure. This guide covers the administration of oxygen, types of oxygen supply, safety precautions, and devices used for oxygen delivery. Safety measures include avoiding smoki

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Oxygen inhalation is a vital medical intervention to treat low blood oxygen levels in children with respiratory issues. It helps manage hypoxia, maintain oxygen levels in the blood, and support normal cellular function. Common indications include cyanosis, breathlessness, anemia, and exposure to low

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Blood collection is a crucial process in medical investigations where blood is withdrawn from patients for analysis. Methods include arterial sampling, venipuncture, and fingerstick sampling, each serving specific purposes. Venous blood is preferred over arterial blood due to accessibility and ease

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Oxygenation is a vital aspect of medical care, involving the process of delivering oxygen to the body's cells. It includes measures such as Arterial Oxygen Saturation, Oxygen Delivery, Oxygen Consumption, and Oxygen Extraction. Understanding hypoxia and hypoxemia, as well as the mechanisms of hypoxe

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