Surgical Prophylaxis and Antimicrobial Selection Guidelines in Surgery
Surgical prophylaxis involves administering antibiotics before contamination of previously sterile tissues to prevent infections. Common pathogens in surgical site infections include skin flora like S. aureus. Antimicrobial selection is based on the surgical procedure, likely pathogens, and safety c
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Update on HIV and AIDS Prevention Guidelines 2022
This update highlights key points from the PMK No. 23/2022 on combating HIV, AIDS, and STIs. It covers terminologies, goals for eliminating HIV and AIDS by 2030, and strategies such as PrEP and PEP. The guidelines emphasize timely interventions like Post-Exposure Prophylaxis (PEP) and Pre-Exposure P
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Antimicrobial Susceptibility Testing Market
Antimicrobial susceptibility testing (AST) is a laboratory procedure to identify the right antimicrobial regimen against microbes. Thus, AST of the causative agent(s) is essential for the timely selection of appropriate antimicrobial therapy.
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Overview of WHONET: A Powerful Tool for Antimicrobial Resistance Surveillance
WHONET is a free software used worldwide for managing and analyzing microbiology laboratory data, with a focus on antimicrobial resistance. It offers features like %RIS analysis, MDR tracking, and outbreak detection, benefiting various sectors including healthcare, research, and policy-making. BacLi
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Utilizing Audits for Antimicrobial Stewardship in General Practice
The importance of audits in antimicrobial stewardship is highlighted in this informative content covering topics like why audit and feedback are crucial, sources of prescribing data, available audit tools, practical tips, and a case study showcasing the positive impact of audits in UTI management. T
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Antimicrobial Coatings Market: Exploring Sustainable Approaches to Microbial Con
The Antimicrobial Coatings Market is projected to reach $12.41 billion by 2031, at a CAGR of 10.8% from 2024 to 2031. The antimicrobial coatings help to keep surfaces pathogen-free by obstructing the growth of fungi, bacteria, and other parasites. Antimicrobial coatings provide long-lasting protecti
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Antimicrobial Susceptibility Testing Market
Government initiatives for combating multidrug resistance are expected to boost the need for antimicrobial susceptibility testing products, thereby driving the growth of the global antimicrobial susceptibility testing market.
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Trends in Gonococcal Resistance to Therapies in England and Wales Since 2011 Guideline Change
Antimicrobial resistance in Neisseria gonorrhoeae poses challenges for treatment. This study examines trends in ceftriaxone, azithromycin, and cefixime resistance since the 2011 guideline change in the UK. Data from the Gonococcal Resistance to Antimicrobial Surveillance Programme is analyzed to tra
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Food Preservation with Antimicrobial Preservatives
Food preservation with antimicrobial preservatives involves the use of chemical compounds to prevent or delay food spoilage. These compounds, either naturally present or added during processing, can kill microorganisms or control their growth in foods. Factors for evaluating the suitability of an an
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Understanding HIV Post-Exposure Prophylaxis (PEP) and Prevention
HIV Post-Exposure Prophylaxis (PEP) is a crucial emergency medical response for individuals exposed to HIV, aiming to prevent infection. It involves a regimen of medications, tests, and counseling services initiated within 72 hours of exposure. HIV transmission occurs through body fluids like blood,
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Key Changes in Global Fund's Grant Cycle 7 (GC7) for 2023-2025 Allocation Cycle
New Programme Essentials introduced in GC7 focus on critical interventions to achieve global targets on HIV, TB, and Malaria, emphasizing human rights, gender equality, and community responses. The essentials cover areas such as HIV prevention, testing, treatment, and care, including key elements li
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Ideal Antimicrobial Agents and Antimicrobial Classification Overview
This lecture on general chemotherapy outlines the properties of ideal antimicrobial agents, emphasizing selective and effective activity, bactericidal action, non-toxicity, and more. It also covers the classification of antimicrobials based on chemical structure, including sulfonamides, diaminopyrim
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Overview of Epidemiological Cutoff Values (ECVs) in Antimicrobial Susceptibility Testing
Epidemiological Cutoff Values (ECVs) are crucial in determining antimicrobial susceptibility by distinguishing wild-type and non-wild-type microbial populations. ECVs are defined based on factors like minimal inhibitory concentration (MIC) and genetic variation, and are determined through specific m
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Understanding the Role of Starter Culture in Fermented Milk Products
Starter cultures play a crucial role in the production of fermented milk products by producing antimicrobial compounds like organic acids, H2O2, CO2, aroma compounds, fatty acids, and bacteriocins. These compounds help prevent spoilage by inhibiting the growth of harmful bacteria and altering cellul
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Combatting Antimicrobial Resistance: A Comprehensive Approach
Infectious Diseases class covers topics such as antibiotic stewardship, bacterial infections, viral diseases, and more. Cautionary statements by Sir Alexander Fleming underline the dangers of antimicrobial resistance, predicting millions of deaths and trillions in economic costs by 2050. The consequ
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Advances in Antimicrobial Drugs: Selective Toxicity and Classification
The development of antimicrobial drugs has significantly improved therapeutics by controlling infections and preventing complications. These drugs target invading microorganisms using selective toxicity, sparing host cells. Antimicrobial drugs are classified based on site, mechanism of action, and c
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Antibiotic Prophylaxis Compliance in Rural Queensland Hospitals
Antibiotic prophylaxis is crucial in surgeries to prevent infections. This study aims to determine compliance with prophylactic antibiotic use in surgeries conducted at Gympie, Dalby, and Kingaroy general hospitals in Southeast Queensland. The primary objective is to compare adherence to guidelines
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Enhancing Livestock Health Through Early Diagnostics and Targeted Antimicrobial Use
Utilizing early diagnostics in livestock for targeted antimicrobial administration is essential for effective disease management and reducing antimicrobial resistance. This approach aids in timely treatment, facilitates monitoring of animal health status, and supports preventive measures against eme
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Understanding Antimicrobial Stewardship in Healthcare
Exploring the critical aspects of antimicrobial stewardship, including the reasons for antibiotic resistance, considerations for prescribing antibiotics, stewardship checklists, and the role of toolkits in promoting responsible antibiotic use to combat resistance. The importance of monitoring, docum
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Biomedical Recommendations for Doxycycline Post-Exposure Prophylaxis
This clinical guideline discusses the use of doxycycline post-exposure prophylaxis (PEP) to prevent bacterial sexually transmitted infections (STIs) such as syphilis, chlamydia, and gonorrhea. It provides evidence-based recommendations for offering doxy-PEP to individuals engaging in condomless sex
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ECDC Point Prevalence Survey of Healthcare-associated Infections and Antimicrobial Use in European Acute Care Hospitals 2016-2017 Protocol v5.3 Forms
This protocol outlines the data collection form for the ECDC Point Prevalence Survey focusing on healthcare-associated infections and antimicrobial use in European acute care hospitals during 2016-2017. The detailed form covers various aspects such as hospital information, infection control measures
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Global Antimicrobial Resistance Surveillance Market
The Global Antimicrobial Resistance Surveillance Market Size is anticipated to exceed USD 9.92 Billion by 2032, Growing at a CAGR of 5.8% from 2022 to 2032.\n
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Prevention of Surgical Site Infections: Key Factors and Recommendations
Surgical site infections (SSIs) are a significant concern in healthcare settings, with 25% of healthcare-associated infections being SSIs. They are preventable, but still pose challenges due to multifactorial causes. Risk factors include uncontrolled diabetes, obesity, smoking, and length of preoper
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Bloodborne Pathogens Exposure: HIV Post Exposure Prophylaxis Regimen
Take immediate action for exposure to bloodborne pathogens like HIV and Hepatitis C through a post-exposure prophylaxis (PEP) regimen. Administer PEP within 48 hours for increased-risk exposures like needle sticks or contact with infected fluids. Coordinate evacuation if needed and conduct Rapid Dia
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Surgical Hand Antisepsis in the Operating Room Setting
Achieving effective surgical hand antisepsis is crucial in the operating room to reduce the risk of surgical site infections. This involves using antimicrobial agents and sterile brushes to remove debris and microorganisms, reduce microbial counts, and prevent rapid growth. The process requires equi
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Stress Ulcer Prophylaxis in ICU - Adverse Reactions Reporting Guidelines
Guidelines for reporting adverse reactions in Stress Ulcer Prophylaxis in the Intensive Care Unit (SUP-ICU), including definitions of Adverse Reactions (AR), Serious Adverse Reactions (SAR), Adverse Events (AE), Serious Adverse Events (SAE), SARs in SUP-ICU, and SUSARs. Specific conditions considere
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Understanding Antimicrobial Stewardship: Key Concepts and Importance
Explore the critical aspects of Antimicrobial Stewardship, including its definition, historical background, and the impact of antimicrobial resistance. Learn about the basics, such as the relationship between antimicrobial use and resistance patterns, as well as the importance of optimizing antimicr
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Antibiotic Prophylaxis in Perioperative Care
Explore the rational approach to perioperative antibiotic use, the importance of antibiotic stewardship in the operating room, and guidelines for selecting and administering antibiotics to prevent surgical site infections. Understand when antibiotic prophylaxis is necessary, which antibiotics to use
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Optimised Live/Dead Fluorescence Spectrometry for Antimicrobial Susceptibility Testing
This study focuses on the optimisation of live/dead fluorescence spectrometry for rapid antimicrobial susceptibility testing. The research uses fluorescent dyes to distinguish between live and dead cells, providing a potential method for quick antimicrobial resistance diagnostics. The experiment inv
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Complexities of Antimicrobial Resistance in Farm Animals and Public Health
The epidemiology of antimicrobial resistance is multifaceted, involving various sectors such as aquaculture, soil, wildlife, human-animal interfaces, and more. The case study on ceftiofur resistance in chickens highlights the impact of antibiotic use on resistance levels in both animals and humans.
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F/TAF vs. F/TDF for HIV Pre-Exposure Prophylaxis: DISCOVER Study Findings
Study results reveal that F/TAF provides rapid onset and longer sustained HIV protection compared to F/TDF in pre-exposure prophylaxis. The randomized noninferiority trial included 2694 participants with a primary analysis at weeks 48 and 96. Disclosure statements indicate involvement of various hea
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Phytochemical Screening and Antimicrobial Assessment of Mimosa pudica
This study explores the antimicrobial potential of Mimosa pudica extracts through phytochemical screening. Researchers investigated the leaves' antimicrobial characteristics and screened for phytochemical compositions to understand their effects on various microorganisms. The methodology involved sa
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Antimicrobial Prophylaxis for Surgical Site Infection Prevention in Orthopedics
Surgical site infections (SSIs) are common and costly healthcare-associated infections, accounting for a significant percentage of nosocomial infections. Defined by the CDC, SSIs occur within 30 days of surgery and have clinical criteria such as purulent exudate, positive cultures, or surgeon diagno
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Challenges in Prescribing the Right Antimicrobial Agents
Prescribing the appropriate antimicrobial medication can be a daunting task due to various factors. In this case discussion, the patient is on multiple medications for different conditions, making it essential to carefully consider the choice of antimicrobial. Factors such as drug interactions, pati
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Renal Function Monitoring in the PROUD Study: Truvada Pre-Exposure Prophylaxis Trial
Renal function in the PROUD study, a pragmatic open-label randomized trial of Truvada as pre-exposure prophylaxis, was monitored closely. No significant safety concerns were found, with similar renal adverse events between the placebo and Truvada groups. Regular monitoring included baseline serum cr
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American Society of Hematology 2021 Guidelines for Venous Thromboembolism in Cancer Patients
The American Society of Hematology (ASH) 2021 guidelines provide recommendations for preventing and treating venous thromboembolism (VTE) in cancer patients. The guidelines cover primary prophylaxis for hospitalized medical patients and those undergoing surgery, emphasizing the use of thromboprophyl
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Comparing Adherence to HIV Pre-exposure Prophylaxis (PrEP) Among New Male PrEP Users Initiating F/TAF vs. F/TDF
This study aims to describe real-world use patterns and HIV seroconversion rates for individuals using emtricitabine/tenofovir disoproxil fumarate (F/TDF) vs. emtricitabine/tenofovir alafenamide (F/TAF) as pre-exposure prophylaxis (PrEP) for HIV prevention. The retrospective analysis includes newly
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Comprehensive Guide to Pre-Exposure Prophylaxis (PrEP) for HIV Prevention
Learn about the importance of Pre-Exposure Prophylaxis (PrEP) for preventing HIV acquisition in sexually active individuals, including the need for HIV testing, indications for PrEP, and identifying acute HIV infection. This guide emphasizes the significance of offering PrEP to all at-risk individua
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HIV Opportunistic Infections and Prophylaxis Overview
Opportunistic infections (OI) are a major concern for individuals with HIV, often accelerating disease progression and causing severe complications. Prophylactic measures such as TB prophylaxis, Clo-trimazole, and Fluconazole are essential to prevent OIs and improve the overall health outcomes of pe
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Insights into Healthcare-Associated Infections and Antimicrobial Use in Acute Care Settings
This report presents findings from a Point Prevalence Survey (PPS) on Healthcare-Associated Infections (HAI) and Antimicrobial Use (AMU) in acute care, highlighting the prevalence rates, distribution of infections, changes in infection rates, and patterns of antimicrobial consumption across European
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