Surgical prophylaxis involves administering antibiotics before contamination of previously sterile tissues to prevent infections. Common pathogens in surgical site infections include skin flora like S. aureus. Antimicrobial selection is based on the surgical procedure, likely pathogens, and safety c

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This update highlights key points from the PMK No. 23/2022 on combating HIV, AIDS, and STIs. It covers terminologies, goals for eliminating HIV and AIDS by 2030, and strategies such as PrEP and PEP. The guidelines emphasize timely interventions like Post-Exposure Prophylaxis (PEP) and Pre-Exposure P

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Antimicrobial susceptibility testing (AST) is a laboratory procedure to identify the right antimicrobial regimen against microbes. Thus, AST of the causative agent(s) is essential for the timely selection of appropriate antimicrobial therapy.

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WHONET is a free software used worldwide for managing and analyzing microbiology laboratory data, with a focus on antimicrobial resistance. It offers features like %RIS analysis, MDR tracking, and outbreak detection, benefiting various sectors including healthcare, research, and policy-making. BacLi

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The importance of audits in antimicrobial stewardship is highlighted in this informative content covering topics like why audit and feedback are crucial, sources of prescribing data, available audit tools, practical tips, and a case study showcasing the positive impact of audits in UTI management. T

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The Antimicrobial Coatings Market is projected to reach $12.41 billion by 2031, at a CAGR of 10.8% from 2024 to 2031. The antimicrobial coatings help to keep surfaces pathogen-free by obstructing the growth of fungi, bacteria, and other parasites. Antimicrobial coatings provide long-lasting protecti

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Government initiatives for combating multidrug resistance are expected to boost the need for antimicrobial susceptibility testing products, thereby driving the growth of the global antimicrobial susceptibility testing market.

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Antimicrobial resistance in Neisseria gonorrhoeae poses challenges for treatment. This study examines trends in ceftriaxone, azithromycin, and cefixime resistance since the 2011 guideline change in the UK. Data from the Gonococcal Resistance to Antimicrobial Surveillance Programme is analyzed to tra

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Food preservation with antimicrobial preservatives involves the use of chemical compounds to prevent or delay food spoilage. These compounds, either naturally present or added during processing, can kill microorganisms or control their growth in foods. Factors for evaluating the suitability of an an

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HIV Post-Exposure Prophylaxis (PEP) is a crucial emergency medical response for individuals exposed to HIV, aiming to prevent infection. It involves a regimen of medications, tests, and counseling services initiated within 72 hours of exposure. HIV transmission occurs through body fluids like blood,

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New Programme Essentials introduced in GC7 focus on critical interventions to achieve global targets on HIV, TB, and Malaria, emphasizing human rights, gender equality, and community responses. The essentials cover areas such as HIV prevention, testing, treatment, and care, including key elements li

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This lecture on general chemotherapy outlines the properties of ideal antimicrobial agents, emphasizing selective and effective activity, bactericidal action, non-toxicity, and more. It also covers the classification of antimicrobials based on chemical structure, including sulfonamides, diaminopyrim

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Epidemiological Cutoff Values (ECVs) are crucial in determining antimicrobial susceptibility by distinguishing wild-type and non-wild-type microbial populations. ECVs are defined based on factors like minimal inhibitory concentration (MIC) and genetic variation, and are determined through specific m

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Starter cultures play a crucial role in the production of fermented milk products by producing antimicrobial compounds like organic acids, H2O2, CO2, aroma compounds, fatty acids, and bacteriocins. These compounds help prevent spoilage by inhibiting the growth of harmful bacteria and altering cellul

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The development of antimicrobial drugs has significantly improved therapeutics by controlling infections and preventing complications. These drugs target invading microorganisms using selective toxicity, sparing host cells. Antimicrobial drugs are classified based on site, mechanism of action, and c

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Antibiotic prophylaxis is crucial in surgeries to prevent infections. This study aims to determine compliance with prophylactic antibiotic use in surgeries conducted at Gympie, Dalby, and Kingaroy general hospitals in Southeast Queensland. The primary objective is to compare adherence to guidelines

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Utilizing early diagnostics in livestock for targeted antimicrobial administration is essential for effective disease management and reducing antimicrobial resistance. This approach aids in timely treatment, facilitates monitoring of animal health status, and supports preventive measures against eme

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Exploring the critical aspects of antimicrobial stewardship, including the reasons for antibiotic resistance, considerations for prescribing antibiotics, stewardship checklists, and the role of toolkits in promoting responsible antibiotic use to combat resistance. The importance of monitoring, docum

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This clinical guideline discusses the use of doxycycline post-exposure prophylaxis (PEP) to prevent bacterial sexually transmitted infections (STIs) such as syphilis, chlamydia, and gonorrhea. It provides evidence-based recommendations for offering doxy-PEP to individuals engaging in condomless sex

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This protocol outlines the data collection form for the ECDC Point Prevalence Survey focusing on healthcare-associated infections and antimicrobial use in European acute care hospitals during 2016-2017. The detailed form covers various aspects such as hospital information, infection control measures

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Surgical site infections (SSIs) are a significant concern in healthcare settings, with 25% of healthcare-associated infections being SSIs. They are preventable, but still pose challenges due to multifactorial causes. Risk factors include uncontrolled diabetes, obesity, smoking, and length of preoper

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Take immediate action for exposure to bloodborne pathogens like HIV and Hepatitis C through a post-exposure prophylaxis (PEP) regimen. Administer PEP within 48 hours for increased-risk exposures like needle sticks or contact with infected fluids. Coordinate evacuation if needed and conduct Rapid Dia

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Guidelines for reporting adverse reactions in Stress Ulcer Prophylaxis in the Intensive Care Unit (SUP-ICU), including definitions of Adverse Reactions (AR), Serious Adverse Reactions (SAR), Adverse Events (AE), Serious Adverse Events (SAE), SARs in SUP-ICU, and SUSARs. Specific conditions considere

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Explore the critical aspects of Antimicrobial Stewardship, including its definition, historical background, and the impact of antimicrobial resistance. Learn about the basics, such as the relationship between antimicrobial use and resistance patterns, as well as the importance of optimizing antimicr

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Explore the rational approach to perioperative antibiotic use, the importance of antibiotic stewardship in the operating room, and guidelines for selecting and administering antibiotics to prevent surgical site infections. Understand when antibiotic prophylaxis is necessary, which antibiotics to use

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This study focuses on the optimisation of live/dead fluorescence spectrometry for rapid antimicrobial susceptibility testing. The research uses fluorescent dyes to distinguish between live and dead cells, providing a potential method for quick antimicrobial resistance diagnostics. The experiment inv

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The epidemiology of antimicrobial resistance is multifaceted, involving various sectors such as aquaculture, soil, wildlife, human-animal interfaces, and more. The case study on ceftiofur resistance in chickens highlights the impact of antibiotic use on resistance levels in both animals and humans.

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Study results reveal that F/TAF provides rapid onset and longer sustained HIV protection compared to F/TDF in pre-exposure prophylaxis. The randomized noninferiority trial included 2694 participants with a primary analysis at weeks 48 and 96. Disclosure statements indicate involvement of various hea

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This study explores the antimicrobial potential of Mimosa pudica extracts through phytochemical screening. Researchers investigated the leaves' antimicrobial characteristics and screened for phytochemical compositions to understand their effects on various microorganisms. The methodology involved sa

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Surgical site infections (SSIs) are common and costly healthcare-associated infections, accounting for a significant percentage of nosocomial infections. Defined by the CDC, SSIs occur within 30 days of surgery and have clinical criteria such as purulent exudate, positive cultures, or surgeon diagno

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Prescribing the appropriate antimicrobial medication can be a daunting task due to various factors. In this case discussion, the patient is on multiple medications for different conditions, making it essential to carefully consider the choice of antimicrobial. Factors such as drug interactions, pati

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Renal function in the PROUD study, a pragmatic open-label randomized trial of Truvada as pre-exposure prophylaxis, was monitored closely. No significant safety concerns were found, with similar renal adverse events between the placebo and Truvada groups. Regular monitoring included baseline serum cr

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The American Society of Hematology (ASH) 2021 guidelines provide recommendations for preventing and treating venous thromboembolism (VTE) in cancer patients. The guidelines cover primary prophylaxis for hospitalized medical patients and those undergoing surgery, emphasizing the use of thromboprophyl

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This study aims to describe real-world use patterns and HIV seroconversion rates for individuals using emtricitabine/tenofovir disoproxil fumarate (F/TDF) vs. emtricitabine/tenofovir alafenamide (F/TAF) as pre-exposure prophylaxis (PrEP) for HIV prevention. The retrospective analysis includes newly

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Learn about the importance of Pre-Exposure Prophylaxis (PrEP) for preventing HIV acquisition in sexually active individuals, including the need for HIV testing, indications for PrEP, and identifying acute HIV infection. This guide emphasizes the significance of offering PrEP to all at-risk individua

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Opportunistic infections (OI) are a major concern for individuals with HIV, often accelerating disease progression and causing severe complications. Prophylactic measures such as TB prophylaxis, Clo-trimazole, and Fluconazole are essential to prevent OIs and improve the overall health outcomes of pe

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This report presents findings from a Point Prevalence Survey (PPS) on Healthcare-Associated Infections (HAI) and Antimicrobial Use (AMU) in acute care, highlighting the prevalence rates, distribution of infections, changes in infection rates, and patterns of antimicrobial consumption across European

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Dive into the Stress Ulcer Prophylaxis in the Intensive Care Unit (SUP-ICU) data entry system led by Dr. Soeren Marker Jensen. Explore screening, randomization, site overview, and data entry processes. Access participant details, edit submitted data, and learn about data entry guidelines. Enter the

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Reduce and prevent catheter-related bloodstream infections in vascular access by addressing extraluminal infection sources and implementing strategies outlined in national drivers such as the NHS Long Term Plan and the Antimicrobial Resistance Action Plan. Recognize the importance of tackling antimi

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Patients with COVID-19 are at higher risk of thrombotic events, and antithrombotic regimens have shown varied results in previous trials. The APOLLO trial investigated the use of apixaban for prophylaxis in outpatients with additional risk factors. Results indicated that low-dose apixaban did not si

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