Metabo-BL Project Kick-Off Meeting Program Overview
The Metabo-BL Project kick-off meeting program outlines the major aims, activities, and planned meetings of the project focused on metabolomics research and regional networking. Key aspects include the establishment of new labs, strategic partnerships, joint research teams, sustainable job creation, and educational initiatives such as a pilot metabolomics course. The program emphasizes administration guidelines, project timelines, and collaboration with regional research groups for mutual benefit and long-term cooperation.
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B, 22.03.2017, 13h Project ERDF CZAT52, Metabo-BL Kick-Off Meeting Petr imek, Wolfgang Buchberger Biology Centre, Czech Academy of Sciences Ceske Budejovice, Czech Republic 1
Project ERDF CZAT52, Metabo-BL The Kick-Off Meeting Program (22.03.2017, 13 h) Meeting Together (Refreshment) Introduction of Key Project Persons and their Role in the Project The Project Administration Without Restrictions: - The Project Time Schedule - The Project Administration Guidelines - The Project Accounts - The Monitoring Periods, Reporting 2
The Major Project Aims Two New Complementary Labs for Metabolomics Research CZ-AT Regional Networking with 6 Strategic Partners The AT-BY-CZ Networking in the Donau-Vltava European Context The Cooperation with the Regional Proteomic and Genomics Research Groups for Metabolomics Two Joint Research Teams for Targeted (BC) and Untargeted MX (JKU), New Sustainable Jobs Joint Research and Development of Complementary MX Analytical Plarforms One Joint Project Grant Application 3 Pilot Research Projects Increased Number of Excelent Papers, 2 Joint Publication Outputs A Pilot Metabolomics Course in the Region for Students and Public A Long-Term Sustainability of the Cooperation 3
A List of Planned Meetings, Workshops and Other Activities YEAR Budejovice Linz Comments 1. Kick-Off Meeting Ceremonial Meeting Meeting of all partners Meeting of LP+PP for Discussion of Instrumentation incl. first project meeting Meeting of LP+PP for discussion Excursion (2d) 1.3.-28.2. 2018 2. Excursion (2d) Minisymposium (1d) Meeting of LP+PP for Discussion Metabolomics course: Part 1 Meeting of all partners Meeting of LP+PP for Discussion Metabolomics Course: Part 2 1.3.-28.2. 2019 3. Meeting of all partners Meeting of LP+PP for discussion Minisymposium (1d) Meeting of LP+PP for discussion 1.3.-28.2. 2020 Comment 4
The Kick-Off Meeting Program (22.03.2017, 13 h) The Project Administration: - Administration Costs, Administration Facilities - Personal Costs, Salaries - Travel Costs - Publicity: Banners, Panels, Website Creation, Public Relationships - Strategic partners and the Regional Metabolomics Network Implementation - Coordination with Bavarian/OberPfalzer Partners and Others in the Donau-Vltava Region - Excursions, Workshops, Symposia - Study Programs, Exchange of Students - Metabolomics Course 5
The Kick-Off Meeting Program (22.03.2017) The Project Scientific Program: - The Laboratory Equipment Selection Procedure - The Coordination and Sharing Laboratory Facilities - The Biological Material Resources - Human Resources and People Exchange - Joint and Overlapping Research Teams of BC and JKU 6
The Kick-Off Meeting Program (22.03.2017, 13 h) The Project Workpackages: 1. WP I1: Building-up Lab1 (BC) WP I2: Building-up Lab2 (JKU) 2. WP T1: Lab 2 Implementation (JKU) WP T2: Lab 1 Implementation (BC) 3. WP T3: Proof of Concept WP T3-1: Profiling of Unstable Metabolite of Central Metabolism WP T3-2: Steroid Conjugates in Pathophysiology of Neurodegenerative Diseases WP T3-3: A Holistic Approach to Unsealed Cells: Integration of Metabolomic, Proteomic and Genomic Data 7
The Kick-Off Meeting Program (22.03.2017, 13 h) The Administration Matters BC: Eligible Costs Guideline for Transfers between the Project Items Improved allocation of the budgets Meeting the strategic partners 8
The Kick-Off Meeting Program (22.03.2017, 13 h) The Administration Matters JKU: Mr. Schr tter from the Upper Austrian Government responsible for budgeting and controlling of the Interreg program in Austria. It would be good to make a very few changes in our proposal before the final contract is issued (this should be end of March). The point reconsidered - the events and meetings we have planned I suggest we should go through these points at our meeting next week We were informed that, at the moment most of the budget related to these meetings and events is placed in the wrong category - so probably we will have to make some minor changes. Particularly for the workshops and mini-symposia we have to re-think what we will actually do with the money; at the moment it is budgeted as traveling money which (according to Mr. Schr tter) is only available for members of JKU (from our side) so we will not be able to support students or potential strategic partners unless we transfer some of the money to a different category. We need to make changes to be able to cover the costs. 9
The The ERDF CZAT52 METABO ERDF CZAT52 METABO- -BL Project BL Project LAB1 Targeted Metabolomics Multichannel Metabolomics Analytical Platforms for Quantitative, Targeted Metabolomics Research Channel 1: UHPLC-QqQ MS/MS MRM (+ESI, negESI) Multisampler Multiwash Sample cooler Multicolumn Termostat UHPLC pump QqQ N2 CID EM ESI CM DS 2 Monitors Major Applications RP-UHPLC-MRM for Protic Metabolites (RCF Metabolite Labeling) RP(mixed)-UHPLC-MRM for Steroids RP-UHPLC-MRM for Small, Labile Metabolites (RHA Metabolite Labeling) HILIC UHPLC-MRM for Ionic Metabolites 10
The The ERDF CZAT52 METABO ERDF CZAT52 METABO- -BL Project BL Project LAB1 Targeted Metabolomics Channel 2: SFC-QqQ MS/MS MRM (+ESI, negESI) SFC Control Module Isocratic Pump CDS CO2 Supply Stream Jet Stream Jet ESI ESI Multisampler Sample Cooler Termostat SFC DAD 2 Monitors BPR QqQ Major Applications SFC-MRM for Protic Metabolites (RCF Metabolite Labeling) SFC-MRM for Steroids SFC-MRM for Lipids 11
The The ERDF CZAT52 METABO ERDF CZAT52 METABO- -BL Project BL Project LAB2 Nontargeted Metabolomics (JKU) Channel: CE-Q-TOF HRMS (+ESI, negESI) JKU, pls, add your scheme Major Applications Profiling of Ionic Metabolites 12
Metabolite Coverage Expansion. A Discussion Target (Q) No. No. Metabolite Class Technology Non-Target(S) No. Sugars and Polyols GC-FID, GC-MS 50 50 1 Acid - bases GC-MS, LC-MS 200 150 2 Chiral amino acids GC-MS, GC-FID 40 3 Lipidic fatty acids GC-MS, GC-FID 50 40 4 Phospholipids 130 130 90 5 Sterols/Tocopherols GC-MS 50 30 6 Steroid conjugates RP-LC-MS 50 32 7 Polar metabolites HILIC-LC-MS 180 30 8 Peptides, Hormones RP-LC-MS 50 5 9 Unstable metabolites Spectrophotometry 3 10 Total 760 480 13
A Debate of the Other Issues Time Schedules Joint Research Teams Training of People Equipment Options Spectrometer Budgets Cooperation with Strategic Partners Cooperation in the Donau-Vltava Region, Regensburg university 14
