The World of Developmental and Cell Biology

Developmental biology, stemming from embryology, investigates how organisms evolve from a zygote. It merges various fields like genetics, cell biology, and cancer biology. Cell biology focuses on cell properties and behaviors, using tools like genomics and microscopy. Research areas include cancer cell biology, stem cell biology, and systems biology, offering exciting opportunities for career growth. Engaging in research enhances career prospects and allows for specialization in diverse aspects of biology.

• Developmental Biology
• Cell Biology
• Genetics
• Stem Cell Research
• Systems Biology

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1. Developmental and Cell Biology Major Developmental biology derived from embryology the study of how the zygote gives rise to the organism Developmental biology today encompasses embryology, genetics, evolutionary biology, cell biology, cancer biology, neurobiology and systems biology. Stem cell biology and regenerative medicine are among hottest new areas of developmental biology Cell biology the study of the structural functional and biological properties of cells, the smallest units of life Transport, adhesion, signaling, metabolism, motility, cancer, etc Modern tools are key enabling technologies: Genomics Epigenetics Microscopy (confocal, two-photon, light-sheet, super-resolution) Single cell methods

2. Developmental and Cell Biology Research areas in the Department https://devcell.bio.uci.edu/research/research-areas/ Cancer cell biology Developmental genetics Gene-environment interactions Molecular signaling Neurobiology Organelle biology Stem cell biology STEM education Systems Biology Engaging in BioSci 199 research is one of the best things you can do to further your career goals (Med school, grad school, etc.)

3. Developmental and Cell Biology major Max Plikus lab Mechanisms of regeneration and stem cell control Scar-less wound healing

4. Developmental and Cell Biology major Ken Cho lab systems biology of embryogenesis

5. Developmental and Cell Biology major Blumberg lab gene environment interactions in development How are the effects of environmental exposures transmitted to future generations?

6. Developmental and Cell Biology major Xiaoyu Shi lab How do cells drive developmental mechanisms across all scales?

7. Why major in Developmental and Cell Biology? What do I get? More in depth training in Developmental and Cell biology Can replace 1 upper division lab with Excellence in Research Close interactions with faculty advisors who provide advice and career counseling in addition to BioSci advisors. Specific to your career choices and requirements Recognition of specialization on transcript Department recognition/luncheon, sashes, gifts. D114 - Informal group seminar for majors (spring, including lunch) Build camaraderie, share research experience, hone presentation skills, personal interactions with guest speakers selected by students In 2022 we had the following speakers in D114 Transitioning from academia to industry (Dr. Amanda Janesick) Graduate school admissions (Drs. Sha Sun and Ken Cho) Careers in NGOs (Dr. Alexis Temkin, Environmental Working Group) Using science to advocate for healthy environment (Kim Konte, NTN) Genetic counseling as a career (Pamela Flodman Director, UCI GC) Careers in FDA and public health (Renee Padiernos) Medical school admissions (Dr. Ellena Peterson)

8. Developmental and Cell Biology major Requirements for admission At least junior standing (applications accepted in Spring) 3.0 GPA (in BioSci courses) (but flexible depending on circumstances) Demonstrated interest in subject BioSci 199 strongly encouraged (we can help place you) Strong interest in a biomedical research career is beneficial Required courses 93-99, D103, D104, D145 (winter) 1 Upper division cell biology (menu of 5) 1 upper division developmental biology (menu of 3) 3 electives from a large list of possibilities 100L, D111L, 1 upper division lab (but can petition Excellence) Approval by the Department advisors For more information please contact Bruce Blumberg (blumberg@uci.edu) 824-8573 Ken Cho (kwcho@uci.edu) 824-4067