The Nervous System: Structure and Function

 
The Nervous System
 
I.  General organization of nervous system
 
A.
CNS
    1.  brain
     2.  spinal cord
B.     PNS
  1.  sensory
  2.  motor
    a.  Somatic
    b.  ANS
       -sympathetic
      -parasympathetic
 
II.  Nervous  Supporting  Cells - neuroglia
 
A.
Astrocytes
1.
Connect to
capillaries
2.
Mopping up
chemical
environment of
brain as far as
potassium ions and
neurotransmitters
B.  Microglia
 
1.  spider-like
phagocytes
2.  debris, dead
brain cells, bacteria
C.  Ependymal cells
 
1.  lines cavities in CNS
2.  beating of cilia moves
cerebrospinal fluid
3.  fluid nourishes and cushions
CNS
D.  Oligodendrocytes
 
1.  wrap axons of nerve cells
with fatty layer
2.  produces myelin sheath
3.  speeds conduction
E. Glia cells in general
 
1.  resemble neurons
2.  not excitable
3.  supportive cells
4.  capable of repeated mitosis
5.  gliomas-glial tumors
III.  Neurons
 
A.  Structure
 
1.  cell body
2.  nissl bodies-rer
3.  dendrites
4.  axon
5.  axon hillock
6.  axon collateral
7.  axon terminals
8.  neurotransmitters
9.  synaptic cleft
B.  Myelin sheath
 
1.  functions
2.  PNS-Schwann cell
3.  Node of Ranvier
4.  Can form a pathway for
regrowth of damaged
axon
5.  multiple sclerosis
C.  Neurons classified by function
 
1.  afferent
2.  interneuron
3.  efferent
4.  ganglia
5.  nuclei
D.  Neurons classified by structure
 
1.  multipolar
2.  bipolar
3.  unipolar
IV.  Neuron physiology
 
A.  Resting membrane
potential
B.  Action potential-nerve
impulse
 
C.  Propagation of action potential
 
1.  diagram on board
2.  a lot like dominoes
3. 
http://www.youtube.com/watch?v=7tBWl4GE8rk&NR=1
D.  Anatomy of a synapse
 
1.  presynaptic membrane
2.  synaptic cleft
3.  postsynaptic membrane
4.  synaptic vesicles
5.  receptor sites for transmitter
substance
 
E.  Physiology of synapse
 
1.  action potential arrives
2.  Calcium ion channels
open
3.  synaptic vesicles fuse
with membrane
4.  transmitter substance
released
5.  diffusion of transmitter
substance
6.  binding to receptors
7.  creates a graded
potential
8.  may bring postsynaptic
membrane to threshold
9.  nerve gas-blocks
cholinesterase
 
F.  You tube of synaptic events
 
http://www.youtube.com/watch?v=z3F5dfmQ
3hk
V.  Functional Anatomy of the Brain
     A.  Introduction
 
1.  difficult to talk about
2.  two fistfuls of pinkish/gray
3.  wrinkled
4.  consistency of cold
oatmeal
5.  three pounds
6.  hugely complex
7.  four basic regions
a.  Cerebral hemispheres
b.  Diencephalon
c.  Brain stem
d.  cerebellum
 
B.  Cerebral hemispheres
 
1.  most important part
2.  overshadows
diencephalon and brain
stem
3.  mushroom cap covers
top of stalk
4.  gyri
5.  sulci
6.  fissures-ie longitudinal
cerebral fissure
7.  Lobes of cerebrum
 
a.  Frontal lobe
controls mainly motor
function
b.  Primary motor area
is on the precentral
gyrus -governs
conscious motor
control which can be
mapped
 
Motor homunculus
 
c.  Motor homunculus
 
-specific regions of
the precentral
gyrus control
specific body parts
-finer  the
movements, the
more brain area
needed to control
those movements
 
d.  Premotor area
 
-learned
repetitive
tasks
Typing,
playing piano
Athletes
learn tasks
by visualizing
motions
Ingrained in
this area
e.  Broca’s area
 
speech center
Usually located left cerebral hemisphere
Damage here causes inability to speak
8.  Other important areas of cerebral hemispheres
 
a.  Primary somatic sensory area
b.  Visual area in occipital lobe
c.  Complex memory in the temporal lobe
d.  Note close proximity to olfactory area
e.  Anterior association area-higher intellectual reasoning and
socially acceptable behavior
 
9.  Sensory homunculus
 
C.  Diencephalon
 
1.
Thalamus
     a.  Encloses third vent.
     b.  Screens incoming
sensory messages
2.
Hypothalamus
     a.  ANS center for body
temperature and water
balance
     b.  Regulates pituitary
3.
Epithalamus
     a.  Pineal gland
     b.  Choroid plexus
D.  Brain stem
 
1.  size of thumb
2.  midbrain
3.  pons
4.  medulla
5.  interchange
for sensory and
motor paths
6.  nuclei for
respiratory,
blood pressure,
heart rate, RAS
E.  Cerebellum
 
1.
Cauliflower
shape
2.
Controls
balance and
equilibrium
3.
Produces
smooth and
coordinated
muscular
contractions
VI.  Protection of the
brain
 
A.  Meninges
1.  dura mater
2.  arachnoid
3.  pia mater
B.  CSF
1.  produced
choroid plexi
2.  flow
3.  functions
4.  hydrocephalus
 
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The nervous system is a complex network divided into the central nervous system (CNS) and peripheral nervous system (PNS). Neuroglia, or supporting cells, play vital roles in maintaining the health and function of neurons. Neurons, the fundamental units of the nervous system, vary in structure and function. Explore the intricate world of neurons, neuroglia, and the physiological aspects of neuron function.

  • Nervous System
  • Neuroglia
  • Neurons
  • CNS
  • PNS

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  1. The Nervous System

  2. I. General organization of nervous system A. CNS 1. brain 2. spinal cord B. PNS 1. sensory 2. motor a. Somatic b. ANS -sympathetic -parasympathetic

  3. II. Nervous Supporting Cells - neuroglia A. Astrocytes 1. Connect to capillaries 2. Mopping up chemical environment of brain as far as potassium ions and neurotransmitters

  4. B. Microglia 1. spider-like phagocytes 2. debris, dead brain cells, bacteria

  5. C. Ependymal cells 1. lines cavities in CNS 2. beating of cilia moves cerebrospinal fluid 3. fluid nourishes and cushions CNS

  6. D. Oligodendrocytes 1. wrap axons of nerve cells with fatty layer 2. produces myelin sheath 3. speeds conduction

  7. E. Glia cells in general 1. resemble neurons 2. not excitable 3. supportive cells 4. capable of repeated mitosis 5. gliomas-glial tumors

  8. III. Neurons A. Structure 1. cell body 2. nissl bodies-rer 3. dendrites 4. axon 5. axon hillock 6. axon collateral 7. axon terminals 8. neurotransmitters 9. synaptic cleft

  9. B. Myelin sheath 1. functions 2. PNS-Schwann cell 3. Node of Ranvier 4. Can form a pathway for regrowth of damaged axon 5. multiple sclerosis

  10. C. Neurons classified by function 1. afferent 2. interneuron 3. efferent 4. ganglia 5. nuclei

  11. D. Neurons classified by structure 1. multipolar 2. bipolar 3. unipolar

  12. IV. Neuron physiology A. Resting membrane potential B. Action potential-nerve impulse

  13. C. Propagation of action potential 1. diagram on board 2. a lot like dominoes 3. http://www.youtube.com/watch?v=7tBWl4GE8rk&NR=1

  14. D. Anatomy of a synapse 1. presynaptic membrane 2. synaptic cleft 3. postsynaptic membrane 4. synaptic vesicles 5. receptor sites for transmitter substance

  15. E. Physiology of synapse 1. action potential arrives 2. Calcium ion channels open 3. synaptic vesicles fuse with membrane 4. transmitter substance released 5. diffusion of transmitter substance 6. binding to receptors 7. creates a graded potential 8. may bring postsynaptic membrane to threshold 9. nerve gas-blocks cholinesterase

  16. F. You tube of synaptic events http://www.youtube.com/watch?v=z3F5dfmQ 3hk

  17. V. Functional Anatomy of the Brain A. Introduction 1. difficult to talk about 2. two fistfuls of pinkish/gray 3. wrinkled 4. consistency of cold oatmeal 5. three pounds 6. hugely complex 7. four basic regions a. Cerebral hemispheres b. Diencephalon c. Brain stem d. cerebellum

  18. B. Cerebral hemispheres 1. most important part 2. overshadows diencephalon and brain stem 3. mushroom cap covers top of stalk 4. gyri 5. sulci 6. fissures-ie longitudinal cerebral fissure

  19. 7. Lobes of cerebrum a. Frontal lobe controls mainly motor function b. Primary motor area is on the precentral gyrus -governs conscious motor control which can be mapped

  20. Motor homunculus

  21. c. Motor homunculus -specific regions of the precentral gyrus control specific body parts -finer the movements, the more brain area needed to control those movements

  22. d. Premotor area -learned repetitive tasks Typing, playing piano Athletes learn tasks by visualizing motions Ingrained in this area

  23. e. Brocas area speech center Usually located left cerebral hemisphere Damage here causes inability to speak

  24. 8. Other important areas of cerebral hemispheres a. Primary somatic sensory area b. Visual area in occipital lobe c. Complex memory in the temporal lobe d. Note close proximity to olfactory area e. Anterior association area-higher intellectual reasoning and socially acceptable behavior

  25. 9. Sensory homunculus

  26. C. Diencephalon 1. Thalamus a. Encloses third vent. b. Screens incoming sensory messages 2. Hypothalamus a. ANS center for body temperature and water balance b. Regulates pituitary 3. Epithalamus a. Pineal gland b. Choroid plexus

  27. D. Brain stem 1. size of thumb 2. midbrain 3. pons 4. medulla 5. interchange for sensory and motor paths 6. nuclei for respiratory, blood pressure, heart rate, RAS

  28. E. Cerebellum 1. Cauliflower shape 2. Controls balance and equilibrium 3. Produces smooth and coordinated muscular contractions

  29. VI. Protection of the brain A. Meninges 1. dura mater 2. arachnoid 3. pia mater B. CSF 1. produced choroid plexi 2. flow 3. functions 4. hydrocephalus

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