Safe Handling of Hazardous Drugs: Training Overview

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This presentation provides essential information on safe handling practices for transporting hazardous drugs within healthcare facilities. It covers training modules, types of transport activities, personal protective equipment requirements, packaging guidelines, and safety criteria for labeling and storing hazardous drugs during transport.


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  1. Transport of Hazardous drugs DATE PLACE Disclaimer: This presentation contains information on the general principles for safe handling of hazardous drugs. This presentation cannot account for individual variation among facilities and cannot be considered inclusive of all proper methods of occupational safety. It is the responsibility of the facility management and staff to determine the best course of occupational safety for operations. The American Cancer Society and its partners assume no responsibility for any injury or damage to persons or property arising out of or related to any use of these materials, or for any errors or omissions. Last updated: February 2020

  2. Any staff person that transports hazardous drugs (HDs) throughout the facility. Who should take this training? These staff may include facility administration, pharmacists and nurses. 2

  3. Training Modules + Learning Objectives Types of Transport Activities Outline the common types of hazardous drug transport activities Identify which personal protective equipment (PPE) employees should have access to when transporting hazardous drugs Packaging Hazardous Drugs for Transport Describe the physical criteria for hazardous drug packaging during transport Transporting Hazardous Drugs Safely List the criteria for labels, containers and carts when transporting hazardous drug packaging 3

  4. Types of Transport Activities

  5. HDs that need to be transported within the hospital facility must be clearly labeled, stored, and handled in accordance with applicable national and local regulations. Important information about transport of Hazardous Drugs Reference: 1,2 5

  6. Receiving Area Common Transport Activities Storage + Compounding Area Outside the healthcare facility Patient Area(s) Reference: 1,3 6

  7. Access to Personal Protective Equipment Access to Personal Protective Equipment All personnel who receive HDs from manufacturers or distributors should be trained to wear full PPE Chemotherapy- tested gloves An N95 respirator Disposable Gown Goggles Spill Kit Reference: 2 7

  8. Contents of a spill kit A full-face piece chemical cartridge-type respirator may be needed for events such as large spills Instructions for cleaning up a spill Two pairs of disposable chemical-protective gloves Low permeability, disposable protective garment (gown or coverall, shoe covers) Face shield/ splash goggles Respirator (N95 or better) Absorbent, plastic-backed sheets or spill pads Disposable towels At least two sealable, thick plastic waste disposal bags A disposable scoop for collecting glass fragments A puncture-resistant container Sign saying Caution Hazardous Drug Spill Incident reporting form 8 Reference: 1

  9. 2 Packaging Hazardous Drugs for Transport

  10. Packaging Materials Must Prevent Damage Leakage Contamination Degradation 10 Reference: 1,3

  11. During transport, use packaging containers and materials that will maintain physical: Integrity Stability Sterility Reference: 1,3 11

  12. Pneumatic tubes MUST MUST NOT NOT be used in transport of liquid HDs. 12 Reference: 1,3

  13. Wipe Down Bags and Entry Ports Outside of bags or bottles Should be wiped with moist gauze wetted with alcohol or another appropriate solution Should be wiped with moist alcohol pads and capped Entry ports 13 Reference: 1,3

  14. 3 Transporting Hazardous Drugs Safely

  15. All transport of HD packages should be done in a manner to reduce environmental contamination in the event of accidental dropping. Reference: 3

  16. Containers + Labels + Carts Labels Containers Carts Labeled with a unique identifier and indicating handling precautions Sealed to minimize the risk of breakage or leakage Designed with guards to protect against falling and breakage 16 Reference: 1,3

  17. 17 1. United States Occupational Safety and Health Administration. Controlling Occupational Exposure to Hazardous Drugs [Internet]. [cited 2018 May 5]. 2. Pan American Health Organization. Safe handling of hazardous chemotherapy drugs in limited-resource settings [Internet]. 2013. 3. US Pharmacopeia. USP General Chapter <800> Hazardous Drugs-Handling in Healthcare Settings [Internet]. 2017 [cited 2018 May 7]. References

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