Mediation vs. Moderation in Research

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1
Dr. Oliver Perra
 
Summary
Mediation vs. Moderation
Example of simple mediation model
Practical example of mediation model
The case against the “causal approach”
 
Mediation vs. Moderation
Mediator: Accounts for the relation between predictor and
outcome
 
Mediation vs. Moderation
Mediator: Accounts for the relation between predictor and
outcome
X
Y
Med
 
Mediation vs. Moderation
Mediator: Accounts for the relation between predictor and
outcome
Treatment
 
Mediation vs. Moderation
Mediator: Accounts for the relation between predictor and
outcome
Peer-Support
Depression
Self-efficacy
 
Mediation vs. Moderation
Mediator: Accounts for the relation between predictor and
outcome
Moderator: 
Qualifies
 the association between predictor and
outcome
X
Y
Mod
 
Mediation vs. Moderation
Moderator: 
Qualifies
 the association between predictor and
outcome
Strength of Argument
Changes in Attitudes
Personal
involvement
Environmental taxes
 
Mediation vs. Moderation
Moderator: 
Qualifies
 the association between predictor and
outcome
Strength of Argument
Changes in Attitudes
+ Personal
involvement
Environmental taxes
- Personal
involvement
Strength of Argument
Changes in Attitudes
 
Mediation vs. Moderation
Mediation: 
How
 
predictors influence outcomes
Moderation: 
When 
and
 
for whom
 
predictors influence
outcomes
Simple Mediation Model
 
X
Y
Med
 
Simple mediation model
Mediator: Accounts for the relation between predictor and
outcome
X
Y
M
 
Simple mediation model
X
Y
M
a
b
c
 
Simple mediation model: Ordinary Least Squares
X
Y
M
a
b
c
 
 
Simple mediation model: Ordinary Least Squares
Y
M
a
b
c
X
 
Simple mediation model: Ordinary Least Squares
X
Y
M
a
b
c
 
Simple mediation model: Ordinary Least Squares
X
Y
M
a
b
c
 
X
Y
M
a
b
c
 
Simple mediation model: Ordinary Least Squares
X
Y
M
a
b
c
 
Simple mediation model: Ordinary Least Squares
X
Y
M
a
b
c
 
Simple mediation model: Ordinary Least Squares
X
Y
M
a
b
c
Practical Example
X
Y
Med
 
Example: Students in Grade 8 and 12
Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12.
Some attended private High Schools.
HighInc8
Math12
c
Let’s focus on Family Income at Grade 8 and reading:
Family Income was dichotomised to represent families with higher income.
 
Example: Students in Grade 8 and 12
Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12.
Some attended private High Schools.
Let’s focus on maths and reading:
HighInc8
Math12
Read8
a
b
c
 
Example: Students in Grade 8 and 12
Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12.
Some attended private High Schools.
Let’s focus on maths and reading:
HighInc8
Math12
Read8
a
b
c
 
Example: Students in Grade 8 and 12
Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12.
Some attended private High Schools.
Let’s focus on maths and reading:
HighInc8
Math12
Read8
4.67 ***
b
c
Read8 = 48.59 + 
4.67
 (HighInc8) 
summary(lm(read8~highinc, data=d))
 
Example: Students in Grade 8 and 12
Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12.
Some attended private High Schools.
Let’s focus on maths and reading:
HighInc8
Math12
Read8
4.67 ***
0.60***
2.43***
Read8 = 48.59 + 
4.67
 (HighInc8)
Math12 = 18.39 + 
2.43
 (HighInc8) + 
0.60
 (Read8)
 
summary(lm(math12~highinc+read8, data=d))
 
Example: Students in Grade 8 and 12
Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12.
Some attended private High Schools.
Let’s focus on maths and reading:
HighInc8
Math12
Read8
4.67 ***
0.60***
2.43***
Read8 = 48.59 + 
4.67
 (HighInc8)
Math12 = 18.39 + 
2.43
 (HighInc8) + 
0.60
 (Read8)
Indirect effect = ab  = (
4.67 
*
 
0.60
) 
 
 
2.80
 
 
Example: Students in Grade 8 and 12
Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12.
Some attended private High Schools.
Let’s focus on maths and reading:
HighInc8
Math12
Read8
4.67 ***
0.60***
2.43***
Read8 = 48.59 + 
4.67
 (HighInc8)
Math12 = 18.39 + 
2.43
 (HighInc8) + 
0.60
 (Read8)
Indirect effect = ab  = (
4.67 
*
 
0.60
) ≈ 2.80
 
process (data=d,
y="math12",x="highinc",m="read8",
total=1, normal=1, model=4, seed=90460)
 
Assumption of
normal sampling
distribution and
use of Sobel test
 
Example: Students in Grade 8 and 12
Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12.
Some attended private High Schools.
Let’s focus on maths and reading:
HighInc8
Math12
Read8
4.67 ***
0.60***
2.43***
Read8 = 48.59 + 
4.67
 (HighInc8)
Math12 = 18.39 + 
2.43
 (HighInc8) + 
0.60
 (Read8)
Indirect effect = ab  = (
4.67 
*
 
0.60
) ≈ 2.80
 
process (data=d,
y="math12",x="highinc",m="read8",
total=1, boot=10000, model=4, seed=90460)
 
Requests 10k
draws in
bootstrapping
The case against the “Causal Steps Approach”
 
X
Y
Med
t
 
The case against the “Causal Steps Approach”
X
Y
M
e
a
c
b
t
 
The case against the “Causal Steps Approach”
X
Y
M
e
a
c
b
(1)
Cumbersome
 too many tests;
(2)
Indirect effect 
a*b
 may be 
 0 even if 
a
 and 
b
 are not;
(3)
Investigation stops if total effect is not significant:
However, there may be mediation even if total effect is
not significantly 
 0
 
Summary
Mediation vs. Moderation
Example of simple mediation model
The case against the “causal approach”
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www.ncrm.ac.uk
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This introduction explores the concepts of mediation and moderation in research, distinguishing between how predictors influence outcomes and when they do so. It covers practical examples of mediation models, the role of mediators and moderators, and the importance of considering the relationship between predictors and outcomes.

  • Mediation
  • Moderation
  • Research methods
  • Predictor influence
  • Data analysis

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  1. An Introduction to Mediation and Moderation Part #1 Dr. Oliver Perra

  2. Summary Mediation vs. Moderation Example of simple mediation model Practical example of mediation model The case against the causal approach

  3. Mediation vs. Moderation Mediator: Accounts for the relation between predictor and outcome

  4. Mediation vs. Moderation Mediator: Accounts for the relation between predictor and outcome Med X Y

  5. Mediation vs. Moderation Mediator: Accounts for the relation between predictor and outcome Treatment

  6. Mediation vs. Moderation Mediator: Accounts for the relation between predictor and outcome Self-efficacy Depression Peer-Support

  7. Mediation vs. Moderation Mediator: Accounts for the relation between predictor and outcome Moderator: Qualifies the association between predictor and outcome Mod X Y

  8. Mediation vs. Moderation Moderator: Qualifies the association between predictor and outcome Personal involvement Strength of Argument Changes in Attitudes Environmental taxes

  9. Mediation vs. Moderation Moderator: Qualifies the association between predictor and outcome + Personal involvement Strength of Argument Changes in Attitudes - Personal involvement Strength of Argument Changes in Attitudes Environmental taxes

  10. Mediation vs. Moderation Mediation: Howpredictors influence outcomes Moderation: When andfor whompredictors influence outcomes

  11. Simple Mediation Model Med X Y

  12. Simple mediation model Mediator: Accounts for the relation between predictor and outcome M X Y

  13. Simple mediation model M a a b b X Y c c c ?????? ?????? ? ? ?,? ???????? ?????? ? ?

  14. Simple mediation model: Ordinary Least Squares ?? M a a b b ?? X Y c c ? = ??????????+ ? (?) + ?? ? = ?????????? + ? (?) + ? (?) + ??

  15. Simple mediation model: Ordinary Least Squares ?? M a a b b ?? X Y c c Direct Effect X Y: ? = ??????????+ ? (?) + ?? ? = ?????????? + ? (?) + ? (?) + ?? ? = ? | ? = ?,? = ? ? | ? = ? 1 ,? = ?

  16. Simple mediation model: Ordinary Least Squares ?? M a a b b ?? X Y c c Direct Effect X Y: ? = ??????????+ ? (?) + ?? ? = ?????????? + ? (?) + ? (?) + ?? ? = ? | ? = ?,? = ? ? | ? = ? 1 ,? = ? c is the estimated difference in Y for a unit change of X while holding M constant; adjusted difference.

  17. Simple mediation model: Ordinary Least Squares ?? M a a b b ?? X Y c c ? | ? = ? ? | ? = ? 1 ? = ? = ??????????+ ? (?) + ?? ? = ?????????? + ? (?) + ? (?) + ?? a is the estimated difference in M for a unit change of X.

  18. ?? M a a b b ?? X Y c c ? | ? = ? ? | ? = ? 1 ? = ? = ??????????+ ? (?) + ?? ? = ?????????? + ? (?) + ? (?) + ?? ? = ? | ? = ?,? = ? ? | ? = ? 1,? = ? b is the estimated difference in Y for a unit change of M, while holding X constant.

  19. Simple mediation model: Ordinary Least Squares ?? M a a b b ?? X Y c c The indirect effect of X ? ? Y: ? = ??????????+ ? (?) + ?? ? = ?????????? + ? (?) + ? (?) + ?? Cases that differ by one unit on X are estimated to differ by ab units in Y as a result of the effects X M and M Y

  20. Simple mediation model: Ordinary Least Squares ?? M a a b b ?? X Y c c The total effect of X ? = ? | ? = ? ? = ? + ?? Y: ? | ? = ? 1 ? = ??????????+ ? (?) + ?? ? = ?????????? + ? (?) + ? (?) + ??

  21. Simple mediation model: Ordinary Least Squares ?? M a a b b ?? X Y c c The total effect of X ? = ? | ? = ? ? = ? + ?? ; ? ? = ?? ; Y: ? | ? = ? 1 ? = ??????????+ ? (?) + ?? ? = ?????????? + ? (?) + ? (?) + ??

  22. Practical Example Med X Y

  23. Example: Students in Grade 8 and 12 Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12. Some attended private High Schools. Let s focus on Family Income at Grade 8 and reading: Family Income was dichotomised to represent families with higher income. ??12 Math12 HighInc8 c c

  24. Example: Students in Grade 8 and 12 Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12. Some attended private High Schools. Let s focus on maths and reading: ??8 Read8 a a b b ??12 Math12 HighInc8 c c

  25. Example: Students in Grade 8 and 12 Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12. Some attended private High Schools. Let s focus on maths and reading: ??8 Read8 a a b b ??12 Math12 HighInc8 c c ?(????8) = ??????????+ ? (?_??? ???8) + ?? ? (??? 12) = ?????????? + ? (?_??? ???8) + ? (?_????8) + ??

  26. Example: Students in Grade 8 and 12 Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12. Some attended private High Schools. Let s focus on maths and reading: ??8 summary(lm(read8~highinc, data=d)) Read8 4.67 *** 4.67 *** b b ??12 Math12 HighInc8 c c ?(????8) = ??????????+ ? (?_??? 8) ? (??? 12) = ?????????? + ? (?_??? 8) + ? (?_????8) Read8 = 48.59 + 4.67 (HighInc8)

  27. Example: Students in Grade 8 and 12 Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12. Some attended private High Schools. Let s focus on maths and reading: ??8 summary(lm(math12~highinc+read8, data=d)) Read8 4.67 *** 4.67 *** 0.60*** 0.60*** ??12 Math12 HighInc8 2.43*** 2.43*** ?(????8) = ??????????+ ? (?_??? 8) ? (??? 12) = ?????????? + ? (?_??? 8) + ? (?_????8) Read8 = 48.59 + 4.67 (HighInc8) Math12 = 18.39 + 2.43 (HighInc8) + 0.60 (Read8)

  28. Example: Students in Grade 8 and 12 Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12. Some attended private High Schools. Let s focus on maths and reading: ??8 Read8 4.67 *** 4.67 *** 0.60*** 0.60*** ??12 Math12 HighInc8 2.43*** 2.43*** ?(????8) = ??????????+ ? (?_??? 8) ? (??? 12) = ?????????? + ? (?_??? 8) + ? (?_????8) Read8 = 48.59 + 4.67 (HighInc8) Math12 = 18.39 + 2.43 (HighInc8) + 0.60 (Read8) Indirect effect = ab = (4.67 * 0.60) 2.80

  29. Example: Students in Grade 8 and 12 Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12. Some attended private High Schools. Let s focus on maths and reading: ??8 process (data=d, y="math12",x="highinc",m="read8", total=1, normal=1, model=4, seed=90460) Read8 4.67 *** 4.67 *** 0.60*** 0.60*** Assumption of normal sampling distribution and use of Sobel test ??12 Math12 HighInc8 2.43*** 2.43*** Read8 = 48.59 + 4.67 (HighInc8) Math12 = 18.39 + 2.43 (HighInc8) + 0.60 (Read8) Indirect effect = ab = (4.67 * 0.60) 2.80

  30. Example: Students in Grade 8 and 12 Students assessed in standardised scores of Maths and Reading at grade 8 and grade 12. Some attended private High Schools. Let s focus on maths and reading: ??8 process (data=d, y="math12",x="highinc",m="read8", total=1, boot=10000, model=4, seed=90460) Read8 4.67 *** 4.67 *** 0.60*** 0.60*** Requests 10k draws in bootstrapping ??12 Math12 HighInc8 2.43*** 2.43*** Read8 = 48.59 + 4.67 (HighInc8) Math12 = 18.39 + 2.43 (HighInc8) + 0.60 (Read8) Indirect effect = ab = (4.67 * 0.60) 2.80

  31. The case against the Causal Steps Approach Med X Y

  32. The case against the Causal Steps Approach e M a a b b ? Y X t t c c

  33. The case against the Causal Steps Approach (1) Cumbersome too many tests; (2) Indirect effect a*b may be 0 even if a and b are not; (3) Investigation stops if total effect is not significant: However, there may be mediation even if total effect is not significantly 0 e M a a b b ? Y X t t c c

  34. Summary Mediation vs. Moderation Example of simple mediation model The case against the causal approach

  35. www.ncrm.ac.uk

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