Managing Malnutrition in Children

CME on the
malnourished child
Dr Siri Maartensson
Mr Ribson K Rop, Clinical Nutrition Officer
Kacheliba Sub-County Hospital
03/10/2023
Definition
W/H
 – weight for height, relative to standard weight of healthy child.
Z-score -2 SD 
 MAM (moderate acute malnutrition)
Z-score -3 SD 
 SAM (severe acute malnutrition)
MUAC
 (m
id upper arm circumference), degree of muscle wasting
Ages 1-5 yrs
<11,5 – SAM
11,5-12,5 – MAM
12,5-13,5 – at risk
Lower-limb oedema, periorbital oedema
Malnourishment in children
(combination common)
Kwashiorkor
Protein deficiency
Low-normal MUAC, W/H
Oedema – bilateral pitting
oedema, periorbital oedema
Skin changes
Hair changes – dry, thin hair
Hepatomegaly
Miserable, lethargic, apathetic
Marasmus
Protein and energy deficiency
Wasting – low MUAC, W/H
Thin, flaccid skin, prominent
spine/ribs/pelvis
Alert, irritable
Distended abdomen
(weakened muscles + gas from
small bowel bacterial
overgrowth)
K
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M
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Patophysiological consequences
Anaemia (↑free iron 
 inflammation, infection, cell membrane dysf.)
Compromised immune system – very susceptible to infection
Decreased barrier of skin, gut, respiratory tract
Decreased systemic immunity
Electrolyte imbalance – ↓Ca2+, K+, Zn2+, Mg2+, Cu2+
Metabolic disturbances, susceptible to hypoglycemia, hypothermia
Reduced gut mobility, bacterial overgrowth, villous atrophy, gut
enzyme deficiencies 
 impaired digestion and absorption
Muscle wasting
Micronutrient deficiencies
↓ Vitamin A – xerophtalmia (night blindness, corneal ulcers etc)
↓ Vitamin C – scurvy (impaired collagen, bleeding gum etc)
↓ Iron/Folate/B12 – anaemia
↓ Vitamin D/Calcium – rickets (bone deformity)
↓ Vitamin K – blood clotting abnormalities
↓ Iodine – goitre (thyroid growth)
Clinical assessment - history
Concurrent illness/symtoms
Vomiting/diarrhoea? – frequency, duration, nature (postprandial?)
Recent malaria, respiratory tract infection etc
Behaviour changes, irritability, apathy?
Feeding history
Appetite? Thirst? Food and fluid intake last days?
Breastfeeding – mixed/exclusive? How often and long?
Growth history
Premature? Twin? Growth chart available?
Other medical/family history
HIV/AIDS of mother or child?
Development milestones reached?
Immunization status? Vitamin A supplements?
TB contact?
Clinical assessment – further examination
Physical examination
General appearence, behaviour, mood, level of consciousness
Pallor? Jaundice? Fever?
Hydration assessment difficult 
(SAM causes similar clinic) – important to take history!
Urine output? D/V?
Abdomen – distended? Hepatosplenomegaly?
Skin changes/infection? Rashes?
Oedema – lower-limb, facial
Lab
FHG, at least Hb
PITC
RBS
Possibly U/A - rule out severe proteinuria (nephrotic syndrome), check for UTI
BS for MP´s
Appetite test
In- or outpatient care?
Phases of treatment
1. Stabilization phase
Low protein/fat/energy feeds (F-75) 
 re-start metabolic and physiological
processes, clear oedema (will loose weight initially). Usually 8 feeds/d.
Treat medical complications
No iron supplements! (pro-inflammatory 
 can promote infection)
2. Transition phase
Once appetite return, oedema clears, medical complications are treated (usually
3-7 days)
Possible to increase dietary intake, switch to F-100/RUTF. Gradually increase
amount.
3. Rehabilitation phase
Once tolerating feeds, not loosing weight
To promote rapid growth. Usually 5 feeds/d.
Therapeutic nutrition
Initial cautious feeding – re-start metabolic processes, improve
absorption. Risk of overloading fragile system!
Therapeutic feeds – protein, energy, fats, micronutrients, vitamins. No
iron in F-75/F-100.
F-75 – 75kcal, 0.9g proteins/100 ml. Stabilization phase.
F-100 – 100kcal, 2.9g protein/100 ml. Transition/rehab phase.
RUTF – approx. 500 kcal/92g sachet. Transition/rehab phase. Long
shelf life, suitable for outpatient treatment.
Treatment of medical complications
Blood transfusion
 if needed, caution to avoid fluid overload
Initial 
antibiotics
Severe infection might not be as symtomatic as in healthy child. Might
present with hypothermia, hypoglycemia, lethargic appearence.
Immune response decreased – high risk of infection
Nystatin
 if signs of oral candidiasis
Albendazole
 after stabilization
Avoid iron supplements
 until stable, increases risk of infection
Dehydration/diarrhoea
Diarrhoea common – due to e.g infection, osmotic load of the food,
lactose intolerance.
Oral resuscitation preferred. F-75/F-100 contains Zn.
ReSoMal instead of regular ORS – contains ↓Na+, ↑K+
Resuscitate, approx. 70-100ml/kg in the first 12 hours (5ml/kg every 30 min)
Then give after every loose stool
Therapeutic foods will facilitate recovery of mucosa and restore
digestive enzymes, gastric acid and bile.
EDIT
Following slides prepared by hospital nutritionist Mr Ribson K Rop.
C
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:
F-75
For severe oedema, start with 100 mls/kg bwt/day
Wasting/marasmus only- 130ms/kg bwt/day
Case 1
Edematous Child has weight of 8.9kg, what is the feed?
=100ms×8.9÷8 feeds , incase of three hourly feed
=100mls×8.9÷12 feeds, incase of two hourly feed
C
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2
Child 1
: 6.8kg, no oedema , 3 hourly feed?.............
Child 2
: 8.5 kg, mild (+) oedema, 2 hourly feed? …………
Child 3
: 5.2 kg, severe (+++) oedema, 2 hourly feed? ……..
NOTE:
For F100, child have fully gained appetite and oedema
resolved, so the amount of feed 130 mls/kg/day
F
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n
g
It is best to feed the child with a cup
Encourage the child to finish the feed.
It may be necessary to feed a very weak child with a dropper or
syringe.
Do not use a feeding bottle.
Never leave the child alone to feed.
Catch dribbles by holding a saucer under the cup
F
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a.
Record the amount of feed offered.
b.
After offering the feed orally, measure and record the amount left in cup.
c.
Subtract the amount left from the amount offered to determine the
amount taken orally by the child.
d.
If necessary, give the rest of the feed by NG tube and record this amount.
e.
Estimate and record any amount vomited (and not replaced by more
feed).
f.
Ask whether the child had watery diarrhea (any loose stool) since last
feed. If so, record “yes”.
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Slide Note
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Learn about malnourishment in children, including common types like Kwashiorkor and Marasmus, as well as the physiologic consequences and clinical assessments related to malnutrition. Discover key indicators such as weight-for-height, MUAC, and edema, along with micronutrient deficiencies and how they impact a child's health. This comprehensive overview provides insights into identifying, treating, and preventing malnutrition in young individuals.

  • Malnutrition
  • Children
  • Kwashiorkor
  • Marasmus
  • Nutritional Deficiencies

Uploaded on Sep 23, 2024 | 3 Views


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  1. CME on the malnourished child Dr Siri Maartensson Mr Ribson K Rop, Clinical Nutrition Officer Kacheliba Sub-County Hospital 03/10/2023

  2. Definition W/H weight for height, relative to standard weight of healthy child. Z-score -2 SD MAM (moderate acute malnutrition) Z-score -3 SD SAM (severe acute malnutrition) MUAC (mid upper arm circumference), degree of muscle wasting Ages 1-5 yrs <11,5 SAM 11,5-12,5 MAM 12,5-13,5 at risk Lower-limb oedema, periorbital oedema

  3. Malnourishment in children (combination common) Kwashiorkor Protein deficiency Low-normal MUAC, W/H Oedema bilateral pitting oedema, periorbital oedema Skin changes Hair changes dry, thin hair Hepatomegaly Miserable, lethargic, apathetic Marasmus Protein and energy deficiency Wasting low MUAC, W/H Thin, flaccid skin, prominent spine/ribs/pelvis Alert, irritable Distended abdomen (weakened muscles + gas from small bowel bacterial overgrowth)

  4. Kwashiorkor Kwashiorkor Marasmus Marasmus

  5. Patophysiological consequences Anaemia ( free iron inflammation, infection, cell membrane dysf.) Compromised immune system very susceptible to infection Decreased barrier of skin, gut, respiratory tract Decreased systemic immunity Electrolyte imbalance Ca2+, K+, Zn2+, Mg2+, Cu2+ Metabolic disturbances, susceptible to hypoglycemia, hypothermia Reduced gut mobility, bacterial overgrowth, villous atrophy, gut enzyme deficiencies impaired digestion and absorption Muscle wasting

  6. Micronutrient deficiencies Vitamin A xerophtalmia (night blindness, corneal ulcers etc) Vitamin C scurvy (impaired collagen, bleeding gum etc) Iron/Folate/B12 anaemia Vitamin D/Calcium rickets (bone deformity) Vitamin K blood clotting abnormalities Iodine goitre (thyroid growth)

  7. Clinical assessment - history Concurrent illness/symtoms Vomiting/diarrhoea? frequency, duration, nature (postprandial?) Recent malaria, respiratory tract infection etc Behaviour changes, irritability, apathy? Feeding history Appetite? Thirst? Food and fluid intake last days? Breastfeeding mixed/exclusive? How often and long? Growth history Premature? Twin? Growth chart available? Other medical/family history HIV/AIDS of mother or child? Development milestones reached? Immunization status? Vitamin A supplements? TB contact?

  8. Clinical assessment further examination Physical examination General appearence, behaviour, mood, level of consciousness Pallor? Jaundice? Fever? Hydration assessment difficult (SAM causes similar clinic) important to take history! Urine output? D/V? Abdomen distended? Hepatosplenomegaly? Skin changes/infection? Rashes? Oedema lower-limb, facial Lab FHG, at least Hb PITC RBS Possibly U/A - rule out severe proteinuria (nephrotic syndrome), check for UTI BS for MP s Appetite test

  9. In- or outpatient care?

  10. Phases of treatment 1. Stabilization phase Low protein/fat/energy feeds (F-75) re-start metabolic and physiological processes, clear oedema (will loose weight initially). Usually 8 feeds/d. Treat medical complications No iron supplements! (pro-inflammatory can promote infection) 2. Transition phase Once appetite return, oedema clears, medical complications are treated (usually 3-7 days) Possible to increase dietary intake, switch to F-100/RUTF. Gradually increase amount. 3. Rehabilitation phase Once tolerating feeds, not loosing weight To promote rapid growth. Usually 5 feeds/d.

  11. Therapeutic nutrition Initial cautious feeding re-start metabolic processes, improve absorption. Risk of overloading fragile system! Therapeutic feeds protein, energy, fats, micronutrients, vitamins. No iron in F-75/F-100. F-75 75kcal, 0.9g proteins/100 ml. Stabilization phase. F-100 100kcal, 2.9g protein/100 ml. Transition/rehab phase. RUTF approx. 500 kcal/92g sachet. Transition/rehab phase. Long shelf life, suitable for outpatient treatment.

  12. Treatment of medical complications Blood transfusion if needed, caution to avoid fluid overload Initial antibiotics Severe infection might not be as symtomatic as in healthy child. Might present with hypothermia, hypoglycemia, lethargic appearence. Immune response decreased high risk of infection Nystatin if signs of oral candidiasis Albendazole after stabilization Avoid iron supplements until stable, increases risk of infection

  13. Dehydration/diarrhoea Diarrhoea common due to e.g infection, osmotic load of the food, lactose intolerance. Oral resuscitation preferred. F-75/F-100 contains Zn. ReSoMal instead of regular ORS contains Na+, K+ Resuscitate, approx. 70-100ml/kg in the first 12 hours (5ml/kg every 30 min) Then give after every loose stool Therapeutic foods will facilitate recovery of mucosa and restore digestive enzymes, gastric acid and bile.

  14. EDIT Following slides prepared by hospital nutritionist Mr Ribson K Rop.

  15. Calculation of feeds: Calculation of feeds: F-75 For severe oedema, start with 100 mls/kg bwt/day Wasting/marasmus only- 130ms/kg bwt/day Case 1 Edematous Child has weight of 8.9kg, what is the feed? =100ms 8.9 8 feeds , incase of three hourly feed =100mls 8.9 12 feeds, incase of two hourly feed

  16. Case 2 Case 2 Child 1: 6.8kg, no oedema , 3 hourly feed?............. Child 2: 8.5 kg, mild (+) oedema, 2 hourly feed? Child 3: 5.2 kg, severe (+++) oedema, 2 hourly feed? .. NOTE: For F100, child have fully gained appetite and oedema resolved, so the amount of feed 130 mls/kg/day

  17. Feeding Feeding It is best to feed the child with a cup Encourage the child to finish the feed. It may be necessary to feed a very weak child with a dropper or syringe. Do not use a feeding bottle. Never leave the child alone to feed. Catch dribbles by holding a saucer under the cup

  18. FEEDING UTENSILS FEEDING UTENSILS

  19. AFTER FEED AFTER FEED a. Record the amount of feed offered. b. After offering the feed orally, measure and record the amount left in cup. c. Subtract the amount left from the amount offered to determine the amount taken orally by the child. d. If necessary, give the rest of the feed by NG tube and record this amount. e. Estimate and record any amount vomited (and not replaced by more feed). f. Ask whether the child had watery diarrhea (any loose stool) since last feed. If so, record yes .

  20. Difference (F Difference (F- -75 F100) 75 F100)

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