HLA Typing Market

How Organ Failure Rates and HLA Advances Are Transforming the HLA Typing Market

HLA Typing Market 2022-2029 The HLA Typing Market is projected to expand at a compound annual growth rate (CAGR) of 5.6% from 2022 to 2029, reaching a market value of $1.90 billion by the end of 2029. The increasing incidence of organ failures, coupled with breakthroughs in HLA typing technology, is driving this significant growth. Request For Sample Report: https://www.meticulousresearch.com/request-sample- report/cp_id=5311? Importance of HLA Typing Human Leukocyte Antigen (HLA) genes, present in nearly all nucleated cells, play a critical role in the body s ability to accept or reject allogenic grafts. Therefore, precise HLA matching between donors and recipients is vital for successful organ transplants. As organ transplantation becomes more common due to rising organ failures, the demand for accurate HLA typing is surging. Rising Incidence of Organ Failures The growing prevalence of chronic health conditions such as diabetes, high blood pressure, metabolic syndrome, and chronic kidney disease (CKD) contributes significantly to organ failures. The Centers for Disease Control and Prevention (CDC) reported that around 37 million Americans suffered from CKD in 2021, highlighting the increased likelihood of organ failure and the consequent rise in demand for transplantation. Impact of Organ Transplantation on HLA Typing Demand The increasing number of organ transplant procedures, along with improved success rates and post-transplant outcomes, is positively influencing growth in the HLA typing market. Furthermore, advancements in HLA typing technology are accelerating this expansion. Technological Advancements in HLA Typing Traditional methods for HLA typing relied on serological assays, which had limitations such as low resolution and complications due to polyclonal sera. The advent of Polymerase Chain Reaction (PCR) technology enhanced HLA genotyping accuracy, although it struggled to distinguish between alleles at a locus. More advanced technologies like Sanger sequencing and, more recently, Next Generation Sequencing (NGS) and third-generation sequencing have revolutionized HLA typing. Benefits of Next Generation Sequencing (NGS) NGS allows for high-resolution genotyping through the parallel sequencing of DNA molecules, providing comprehensive characterization of entire HLA genes. Third-generation sequencing offers long reads, reducing PCR bias. These technological advancements have improved the precision of HLA typing, significantly benefiting organ transplant procedures. Innovations by Major Industry Players Major players in the industry are focused on launching innovative HLA typing solutions Page 1 of 3 Meticulous Research| sales@meticulousresearch.com

HLA Typing Market 2022-2029 powered by advanced technologies. For instance, Thermo Fisher Scientific introduced a rapid NGS assay that delivers high-resolution data in just five hours, making it ideal for characterizing HLA genes in solid organs from deceased donors. Similarly, Genome Diagnostics B.V. (GenDx) launched the NGStrack reagent and TRKengine software for HLA typing with chimerism monitoring using NGS technology. Expanding Applications Beyond Organ Transplantation HLA typing is also gaining importance in diagnosing infectious diseases, immune disorders, and cancer. The HLA region is associated with susceptibility to specific diseases, and HLA gene markers are essential in diagnosing autoimmune conditions. For example, the detection of HLA-B27 antigens in white blood cells aids in diagnosing autoimmune diseases like ankylosing spondylitis, reactive arthritis, and juvenile arthritis. Future Outlook for the HLA Typing Market As the demand for organ transplants rises, along with continuous innovations in HLA typing technologies, the market is poised for robust growth in the coming years. The introduction of advanced molecular assays and sequencing platforms is expected to enhance HLA typing accuracy and efficiency, ultimately improving transplant success rates and expanding the scope of HLA testing in broader healthcare applications. Key Industry Players The global HLA Typing Market features key players such as Thermo Fisher Scientific Inc. (U.S.), Bio-Rad Laboratories (U.S.), Qiagen N.V. (Netherlands), Genome Diagnostics B.V. (GenDx) (Netherlands), Illumina, Inc. (U.S.), CareDx (U.S.), Immucor Inc. (U.S.), TBG Diagnostics Limited (Australia), BAG Diagnostic GmbH (Germany), Omixon Inc. (Hungary), Luminex Corporation (U.S.), inno-train Diagnostik GmbH (Germany), Pacific Biosciences of California, Inc. (U.S.), and Fujirebio Holdings, Inc. (Japan). The market is fragmented but dominated by four major players Thermo Fisher Scientific Inc., Becton, Dickinson and Company, and Illumina, Inc. which collectively accounted for 20% 25% of the HLA typing market in 2021. Quick Buy: https://www.meticulousresearch.com/Checkout/18936631? About Meticulous Research Meticulous Research was founded in 2010 and incorporated as Meticulous Market Research Pvt. Ltd. in 2013 as a private limited company under the Companies Act, 1956. Since its incorporation, the company has become the leading provider of premium market intelligence in North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa. Page 2 of 3 Meticulous Research| sales@meticulousresearch.com

HLA Typing Market 2022-2029 The name of our company defines our services, strengths, and values. Since the inception, we have only thrived to research, analyze, and present the critical market data with great attention to details. With the meticulous primary and secondary research techniques, we have built strong capabilities in data collection, interpretation, and analysis of data including qualitative and quantitative research with the finest team of analysts. We design our meticulously analyzed intelligent and value-driven syndicate market research reports, custom studies, quick turnaround research, and consulting solutions to address business challenges of sustainable growth. Contact Us: Meticulous Research Email- sales@meticulousresearch.com Contact Sales- +1-646-781-8004 Connect with us on LinkedIn- https://www.linkedin.com/company/meticulous-research Page 3 of 3 Meticulous Research| sales@meticulousresearch.com