Fetal Circulation

Fetal Circulation
 
Ms.Ashwini.S.Mane
 
Anatomy and Physiology
Fetal Circulation
 
Umbilical cord
 
2 umbilical arteries: return non-oxygenated blood,
fecal waste, CO2 to placenta
 
1umbilical vein: brings oxygenated blood and
nutrients to the fetus
 
 
 
 
Fetus depends on placenta to meet O2 needs
while organs continue formation
 
Oxygenated blood flows from the placenta
 
To the fetus via the 
umbilical vein
 
After reaching fetus the blood flows through the
inferior vena cava
 
 
The differences between fetal and newborn
circulation
 
The fetus received oxygen from the placenta and through the
lungs after birth.
 
The fetal liver doesn’t have the metabolic function that it will
have after birth because the mother performs these functions.
 
Three shunts are present in fetal life:
1.
Ductus venosus: 
connects the umbilical vein to the inferior
vena cava
2.
Ductus arteriosus
: connects the main pulmonary artery to the
aorta
3.
Foramen ovale: 
anatomic opening between the right and left
atrium.
 
Fetal Circulation
 
 
 
The umbilical vein carrying the oxygenated blood (80% saturated)
from the placenta , enters the fetus at the umbilicus and run along
the free margins of the falciform ligaments of the liver , in the liver
, it gives off branches to the lobe of the liver and receives the
deoxygenated blood from the portal vein
 
 
 
The greater portion of the oxygenated blood , mixed with some
portal venous blood , short circuits the liver through the ductus
venous to enter the inferior vena cava and then to right atrium of
the heart
 
 
 
The O2 content of this
mixed blood is thus
reduced , although both
the ductus venous and
hepatic portal/fetal trunk
blood enters the right
atrium through the
inferior vana cava, there is
a little mixing
 
The terminal part of the
IVC receives blood from
the right hepatic vein
 
 
 
 
In the right atrium , most of the well oxygenated (75%) ductus
venous blood is preferentially directed into the foramen ovale by
the valve of the inferior vana cava and crista dividens and passes
in to the left atrium , here it is mixed with small amount of venous
blood returning from the lungs through the pulmonary veins
 
 
The left atrial blood is passed on through the mitral opening into
the left ventricle
 
 
Remaining the lesser amount of the blood (25%), after reaching
the right atrium via the superior and inferior vena cava (carrying
the venous blood from the cephalic and caudal parts of the
fetus respectively) passes through the tricuspid opening into
the right ventricle
 
 
 
During the ventricular systole , the left ventricular blood is
pumped into the ascending and arch of aorta and distributed by
their branches to heart , neck , brain and arms
 
The right ventricular blood with low oxygen content is discharged
into the pulmonary trunk , sinces the resistance in the pulmonary
arteries during fetal life is very high , the main portion of the
blood passes directly through the ductus arteriosus into the
descending aorta bypassing the lungs where it mixes with the
blood from the proximal aorta
 
 
 
70% of cardiac output is
carried out by ductus
arteriosus to the
descending aorta
 
About 40% of the combined
output goes to the placenta
through the umbilical
arteries
 
 
 
 
The deoxygenated blood
leaves the body by of
two umbilical arterie s
to reach the placenta
where it is oxygenated
and get ready for
recirculation
 
 
The mean cardiac
output is comparatively
high in fetus and is
estimated to be 350ml
per kg per minute
 
 
 
Conversion of Fetal to Infant Circulation
 
 
At birth
Clamping the cord shuts down low-pressure system
Increased atmospheric pressure(increased systemic
vascular resistance) causes lungs to inflate with
oxygen
Lungs now become a low-pressure system
 
 
Conversion: Fetal to Infant Circulation
 
Pressure from increased blood flow in the 
left side
 of the heart
causes the foramen ovale to close
 
 
More heavily oxygenated blood passing by the ductus
arteriosus causes it constrict
 
 
Functional closure of the foramen ovale and ductus arteriosus
occurs soon after birth
 
 
Overall anatomic changes are not complete for weeks
 
 
What happens to these special structures after
birth?
 
Umbilical arteries atrophy
 
Umbilical vein becomes part of the fibrous
support ligament for the liver
 
The foramen ovale, ductus arteriosus, ductus
venosus atrophy and become fibrous ligaments
 
 
Overview of Conversion
 
Umbilical cord is clamped
Loose placenta
Closure of ductus venosus
Blood is transported to liver and portal system
Increased systemic resistance
Pressure in right atrium decreased
Change from right to left shunting to left to right blood flow
Increased O2 levels in pulmonary circulation
Closure of the ductus arteriosus
 
 
 
 
Thank You….
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Fetal circulation involves intricate pathways that support oxygen exchange and nutrient delivery from the placenta to the developing fetus. Key structures like the umbilical vein, ductus venosus, and foramen ovale play crucial roles in directing blood flow. Understanding these mechanisms is essential for comprehending the unique physiology of fetal circulation.

  • Fetal Circulation
  • Placenta
  • Oxygen Transport
  • Blood Flow
  • Umbilical Vein

Uploaded on Feb 25, 2025 | 0 Views


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  1. Fetal Circulation Ms.Ashwini.S.Mane

  2. Anatomy and Physiology Fetal Circulation Umbilical cord 2 umbilical arteries: return non-oxygenated blood, fecal waste, CO2 to placenta 1umbilical vein: brings oxygenated blood and nutrients to the fetus

  3. Fetus depends on placenta to meet O2 needs while organs continue formation Oxygenated blood flows from the placenta To the fetus via the umbilical vein After reaching fetus the blood flows through the inferior vena cava

  4. The differences between fetal and newborn circulation The fetus received oxygen from the placenta and through the lungs after birth. The fetal liver doesn t have the metabolic function that it will have after birth because the mother performs these functions. Three shunts are present in fetal life: 1. Ductus venosus: connects the umbilical vein to the inferior vena cava 2. Ductus arteriosus: connects the main pulmonary artery to the aorta 3. Foramen ovale: anatomic opening between the right and left atrium.

  5. Fetal Circulation

  6. The umbilical vein carrying the oxygenated blood (80% saturated) from the placenta , enters the fetus at the umbilicus and run along the free margins of the falciform ligaments of the liver , in the liver , it gives off branches to the lobe of the liver and receives the deoxygenated blood from the portal vein The greater portion of the oxygenated blood , mixed with some portal venous blood , short circuits the liver through the ductus venous to enter the inferior vena cava and then to right atrium of the heart

  7. The O2 content of this mixed blood is thus reduced , although both the ductus venous and hepatic portal/fetal trunk blood enters the right atrium through the inferior vana cava, there is a little mixing The terminal part of the IVC receives blood from the right hepatic vein

  8. In the right atrium , most of the well oxygenated (75%) ductus venous blood is preferentially directed into the foramen ovale by the valve of the inferior vana cava and crista dividens and passes in to the left atrium , here it is mixed with small amount of venous blood returning from the lungs through the pulmonary veins The left atrial blood is passed on through the mitral opening into the left ventricle

  9. Remaining the lesser amount of the blood (25%), after reaching the right atrium via the superior and inferior vena cava (carrying the venous blood from the cephalic and caudal parts of the fetus respectively) passes through the tricuspid opening into the right ventricle

  10. During the ventricular systole , the left ventricular blood is pumped into the ascending and arch of aorta and distributed by their branches to heart , neck , brain and arms The right ventricular blood with low oxygen content is discharged into the pulmonary trunk , sinces the resistance in the pulmonary arteries during fetal life is very high , the main portion of the blood passes directly through the ductus arteriosus into the descending aorta bypassing the lungs where it mixes with the blood from the proximal aorta

  11. 70% of cardiac output is carried out by ductus arteriosus to the descending aorta About 40% of the combined output goes to the placenta through the umbilical arteries

  12. The deoxygenated blood leaves the body by of two umbilical arterie s to reach the placenta where it is oxygenated and get ready for recirculation The mean cardiac output is comparatively high in fetus and is estimated to be 350ml per kg per minute

  13. Conversion of Fetal to Infant Circulation At birth Clamping the cord shuts down low-pressure system Increased atmospheric pressure(increased systemic vascular resistance) causes lungs to inflate with oxygen Lungs now become a low-pressure system

  14. Conversion: Fetal to Infant Circulation Pressure from increased blood flow in the left side of the heart causes the foramen ovale to close More heavily oxygenated blood passing by the ductus arteriosus causes it constrict Functional closure of the foramen ovale and ductus arteriosus occurs soon after birth Overall anatomic changes are not complete for weeks

  15. What happens to these special structures after birth? Umbilical arteries atrophy Umbilical vein becomes part of the fibrous support ligament for the liver The foramen ovale, ductus arteriosus, ductus venosus atrophy and become fibrous ligaments

  16. Overview of Conversion Umbilical cord is clamped Loose placenta Closure of ductus venosus Blood is transported to liver and portal system Increased systemic resistance Pressure in right atrium decreased Change from right to left shunting to left to right blood flow Increased O2 levels in pulmonary circulation Closure of the ductus arteriosus

  17. Thank You.

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