Explore Heterocyclic Compounds and Nomenclature
Discover the world of heterocyclic compounds, including their structures, nomenclature, and common elements. Learn about important naming conventions and suffixes for different ring structures. Familiarize yourself with a variety of heterocyclic compounds containing elements such as oxygen, nitrogen, and sulfur. Enhance your knowledge of these intriguing chemical entities through detailed descriptions and images.
Download Presentation
Please find below an Image/Link to download the presentation.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author. If you encounter any issues during the download, it is possible that the publisher has removed the file from their server.
You are allowed to download the files provided on this website for personal or commercial use, subject to the condition that they are used lawfully. All files are the property of their respective owners.
The content on the website is provided AS IS for your information and personal use only. It may not be sold, licensed, or shared on other websites without obtaining consent from the author.
E N D
Presentation Transcript
Wel -Come Heterocyclic Compounds
Dr. Lamture S.V. Head & Asso.Prof. Department of Chemistry .
Heterocycles Ring compounds with elements other than carbon in the ring. The most common elements to appear in heterocyclic compounds are oxygen, nitrogen and sulfur. The aliphatic heterocycles are similar to the open chain analogues, ethers, amines and sulfides. The aromatic heterocycles are similar to other aromatic compounds.
Heterocyclic Nomenclature Replacement nomenclature (IUPAC recommended 1957) Oxygen oxa Sulfur thia Nitrogen aza Lowest number assigned to the hetero atom with the highest precedence: O > S > N NH S O thiacyclobutane 1-oxa-3-azacyclopentane
Hantzsch-Widman (1888) Suffixes Ring members ring with nitrogen ring without nitrogen unsat dsat dunsat dsat d 3 -irine -iridine irene irine 4 ete etidine ete etane 5 ole olidine ole olane 6 ine perhydro__ine in ane 7 epine perhydro__epine epin epane
You must know the * names O N H S * oxirane ethylene oxide oxacyclopropane * thiirane ethylene sulfide thiacyclopropane * aziridine ethylene imine azacyclopropane H N N N N O diazirane 1-azirine oxaziridine oxazacyclopropane
O S NH oxetane oxacyclobutane azetidine azacyclobutane thietane thiacyclobutane N N azete azacyclobutadiene 1-azetine 1-azacyclobutene
O N H S * furan oxole oxacyclopentandiene * thiophene thiole thiacyclopentandiene * pyrrole O N H O O 1,3-dioxolane 1,3-dioxacyclopentane * tetrahydrofuran * pyrrolidine azacyclopentane
N N N N N H N H N H imidazole pyrazole 1,2,4-triazole N N N S O O oxazole isooxazole thiazole
O O O O O 4-pyrone 4-hydropyran 2-pyrone H N O N H N H O piperazine * piperidine * 1,4-dioxane
N N NN N N pyridazine pyrimidine pyrazine O N N H * morpholine * pyridine
5 4 5 4 6 3 6 3 N2 7 7 2 N 1 8 1 8 * isoquinoline * quinoline N H * indole
