The OCTIVUS Randomized Clinical Trial compared the clinical efficacy and safety of Optical Coherence Tomography (OCT)-guided and Intravascular Ultrasound (IVUS)-guided strategies in patients undergoing PCI for significant CAD. The study aimed to determine if OCT-guided PCI is noninferior to IVUS-gui

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This prospective, multicentre, randomised clinical trial led by Dr. Tiffany Patterson aims to determine whether direct delivery to a cardiac arrest centre following non-ST elevation out-of-hospital cardiac arrest reduces deaths compared to delivery to the nearest emergency department. Funded by the

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This UK-wide clinical trial aims to assess the effectiveness of early peripheral norepinephrine infusion in adult patients with septic shock. The study will compare the impact on mortality and other outcomes of targeting a mean arterial pressure (MAP) above 65mmHg within the first 48 hours of admiss

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Enhance your trial presentation skills with insights from Judge Renee A. Goble of Denver County Court. Learn about trial structure, direct and cross-examination techniques, understanding evidence, objections, and more to improve your courtroom performance.

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Preliminary principles and rules regarding hearsay in Virginia courts, including the effective date of the Virginia Rules of Evidence, application of rules in various trial scenarios, criteria for admissibility of evidence by trial judges, and reasons for the legal distrust of hearsay evidence. The

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Empagliflozin's impact on cardiovascular and renal events in heart failure with reduced ejection fraction was assessed in the EMPEROR-Reduced trial led by Milton Packer, MD, and Faiez Zannad, MD. The trial, enriched for patients with severe left ventricular dysfunction, randomized participants to em

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Explore the process of simulating clinical trial designs, including traditional and adaptive approaches. Learn how to generate data, conduct analysis, make within-trial decisions, and summarize results using fixed-sample two-arm parallel group trials and group-sequential designs. Dive into methods l

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The UK Mini Mitral Trial compares the outcomes of minimally invasive thoracoscopic-guided right minithoracotomy versus conventional sternotomy for mitral valve repair. The trial aims to determine if physical function improvement post-surgery at 12 weeks is superior in the minimally invasive approach

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Explore the various types of hearings available in the Court Management System, such as Motion Calendar, Special Sets, Calendar Call/Trial, Pre-Trial Conference, and Case Management. Learn how to set up new hearings/events and understand the process of generating trial orders and pre-trial conferenc

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The STRESS-L Trial focuses on reversing septic shock using Landiolol, a beta-blockade treatment. It provides training for non-GCP trained clinicians involved in eligibility review, medical care, and prescribing in the trial. The slides cover key GCP principles, trial agenda, study information, backg

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The CLEAR Trial is a 2x2 factorial randomized trial evaluating the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the trial focuses on clinical and c

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ACST-2 is a randomized trial comparing carotid artery stenting (CAS) versus carotid artery surgery (CEA) in asymptomatic patients with severe carotid stenosis. The trial, published in The Lancet in August 2021, involved 3625 patients. While surgery has been shown to reduce stroke rates, modern medic

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The Sixth Amendment guarantees various rights during criminal trials, such as a speedy and public trial, trial by jury, notice of accusations, the right to confront witnesses, and the assistance of counsel. Defendants can opt for a bench trial where the judge decides innocence or guilt. Juries, typi

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The CLEAR Trial is a 2x2 factorial randomized trial examining the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the study focuses on exacerbation ma

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Explore the top 10 trial traps, tricks, and techniques presented by Judge Joyce Draganchuk from Ingham County Circuit Court. Learn about self-representation requirements, managing disruptive defendants, challenges in jury selection, and more essential insights for a successful trial practice.

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NCI-MATCH is a groundbreaking clinical trial aiming to match tumor gene alterations with targeted therapies. The interim analysis results revealed impressive patient enrollment and site participation exceeding expectations. Despite challenges with pausing new patient registrations for the analysis,

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Understanding the key components of a clinical trial research protocol is essential for conducting successful studies. This includes identifying session objectives, discussing trial protocol contents, exploring observational study elements, and learning about reporting guidelines. Study objectives f

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Enhance your trial skills in family law with a focus on evidence collection, trial strategies, and client examination. Learn best practices for preserving evidence, drafting persuasive statements, and navigating trials confidently. This workshop covers important aspects of evidence collection, such

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Explore the innovative tool nQuery Predict for accurate clinical trial milestone predictions, demonstrated in a webinar hosted by industry experts. Learn about key milestones, adaptive design considerations, enrollment predictions, and the significance of statistical approaches in optimizing trial d

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Exploring the detailed process of civil rights litigation, covering steps from fact gathering to trial preparation and post-trial activities. The visual presentation showcases key elements such as client retention, complaint filing, discovery phases, trial preparation, and post-trial procedures like

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Simulation competition where students portray attorneys and witnesses in a civil jury trial based on the case of professional writer Riley Winter suing an online magazine for wrongful termination due to age discrimination. Judges preside over the trial, score performances, and provide feedback, focu

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Explore the essentials of election judge training for the 2024 elections, covering the code of conduct, maintaining neutrality in the polling place, and details on polling place setup and roles. Understand the oath, duties, and responsibilities of an election judge, emphasizing impartiality, profess

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Czech criminal procedure combines inquisitorial and accusatorial models, with the pre-trial phase led by the public prosecutor and the trial phase overseen by a judge. Inspired by the Anglo-American adversarial system, Czech proceedings feature deviations tailored to the continental model. Key princ

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In this competition, students simulate a criminal jury trial where they take on roles as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves State v. Sinclair, focusing on the murder trial of Skyler Sinclair, a suspect in the death of an undercover officer

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In a mock trial, participants prepare and present cases as legal teams, acting as attorneys and witnesses. The process involves selecting roles, preparing statements, and presenting arguments before a judge. Teams must prove their case with evidence and cross-examination. The article details the ste

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Enhance your trial advocacy skills with effective cross-examination strategies discussed by Professor Stephen A. Saltzburg at the District Court of the Virgin Islands mid-year conference. Learn techniques such as eliciting favorable information, attacking witness credibility, and conducting multiple

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AIRWAYS-3 is a multi-centre, open-label, randomized trial evaluating the clinical and cost effectiveness of a supraglottic airway (SGA) versus tracheal intubation during in-hospital cardiac arrest (IHCA). The trial aims to determine the functional status and health-related quality of life outcomes o

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Explore the latest developments in EU family law from the perspective of a practicing judge, focusing on new regulations, the hearing of the child, and significant changes in cross-border proceedings. Key topics include children's participation in legal proceedings, standards for refusal of recognit

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Discover the essential role of a Chief Judge (CJ) in swim meets, how to become one, qualities needed, and a step-by-step overview of your first session as a CJ. Learn the key responsibilities and traits required for a successful Chief Judge. Dive in and elevate your officiating skills!

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Explore the characteristics of God as the great King and Judge, reflecting on His eternal reign and righteous judgment. Jesus, as the appointed Judge, will determine the destiny of all based on repentance and friendship with Him. Be prepared for His return and the establishment of His kingdom.

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Explore the functions of a Municipal Court, the role of a Municipal Judge, jurisdiction over criminal misdemeanors and traffic offenses, importance of enforcing traffic laws, defendant's options in a trial, the right to a jury trial, and the concept of impartiality in legal proceedings.

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The CLEAR Trial is a 2x2 factorial randomized trial led by Professor Stuart Elborn and Professor Judy Bradley to assess the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves various study sites and potential new sit

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Understanding the role and benefits of partnering with a Clinical Trial Unit (CTU) is essential for potential Chief Investigators. A CTU handles various aspects of trial coordination, from developing trial materials to overseeing regulatory permissions and data management. UK Clinical Trials Units (

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The trial of O.J. Simpson for the brutal murders of Nicole Brown Simpson and Ron Goldman captivated the nation, with overwhelming evidence implicating Simpson. Despite the compelling case against him, Simpson's defense team, led by Johnnie Cochran, raised doubts about the integrity of the evidence a

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Participants are preparing for the trial of King Louis XVI by researching charges, roles, and responsibilities. The trial process includes reading indictments, opening statements, questioning phases, and final statements. Each role, including Louis, Marie, Robespierre, Marat, and a woman from the 3r

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Simulation of a criminal jury trial where students act as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves the attempted murder of Kerry Bell-Leon, with witness selection varying in each round. Judges play crucial roles in presiding over the trial, scor

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The CLEAR Trial, led by Professor Stuart Elborn and Professor Judy Bradley, aims to assess the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves a 2x2 factorial design and various study sites acros

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The CLEAR Trial is a 2x2 factorial randomized trial assessing the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley, the trial involves randomization, sealed

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When judging a debate, it is crucial to be supportive, equitable, and respectful of all participants. Providing opportunities for debaters to state their pronouns and important information, avoiding favoritism, and embracing diversity are key aspects of being a good judge. Actively listening, taking

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This presentation covers the pivotal role of Phase II trials in oncology drug development, emphasizing the importance of preliminary clinical efficacy screening, adverse event profiling, mechanism of action understanding, and target population definition. It discusses various Phase II trial designs,

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