HER2 activation plays a crucial role in promoting tumor proliferation and survival in NSCLC. Driven by oncogenic downstream signaling pathways, HER2 overexpression and gene amplification lead to the formation of heterodimers and activation of key signaling cascades. Additionally, HER2 mutations are

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Families often come into contact with children's social care due to parenting under adversarial conditions rather than causing harm. The need for a change in vision and values underpinning family safeguarding duties is crucial, emphasizing the importance of helping families raise their children. Lad

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The PROTEOCURE COST Action focuses on targeting proteolysis for proteome remodeling, aiming to enhance Europe's scientific and technological capacity through collaboration across various fields and career stages. Participating in this initiative offers financial support, scientific networking, and c

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Praise plays a crucial role in promoting children’s self-esteem and overall development. By offering genuine praise for being and doing, parents can nurture a positive sense of self-worth in their children. Research shows that praised children tend to excel academically, show resilience, and lead

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Explore the potential of targeting human exosomes using a bispecific antibody platform, enhancing drug delivery capabilities. The study delves into engineering exosomes as drug carriers, developing exosome targeting antibodies (ExTAbs), and verifying exosome delivery efficiency. Future directions in

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The public hearing on the regulation of political advertising delves into categorizing personal data, different data types, processing techniques, and associated risks like undermining autonomy and democratic processes. Stakeholders emphasize the need for transparency in targeting and delivery of ad

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Thematic Working Group for Libya Flood Responses held a meeting on 17 October 2023 to discuss coordinated responses, targeting needs and damage assessments. Updates and documents published by partners after 10 October 2023 were shared, including reports from SRSG Abdoulaye Bathily and various agenci

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In the dynamic landscape of cargo services, effective market segmentation and targeting are crucial for maximizing profitability and operational efficiency. Revenue Technology Services s(RTS) plays a pivotal role in advising cargo companies on crafting robust strategies tailored to diverse customer

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The briefing highlights concerning findings from the inspection of Herefordshire children's services, revealing significant weaknesses in social work practice, poor assessments, and insufficient plans to ensure children's safety and well-being. The report identifies systemic issues such as drift, de

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The Child Care and Protection Act of 2015, Chapter 20, addresses harmful social, cultural, and religious practices affecting children in Namibia. The Act prohibits practices detrimental to children's well-being, such as child marriage, and imposes penalties on those who subject children to such prac

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Gain valuable insights into the risks children face online, including key facts about internet and mobile technology usage, ways to address and prevent risks, and resources for parents and children. Discover statistics on children's online behavior and the prevalence of social networking among vario

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The Palak Mata Pita Yojana in Gujarat provides financial assistance to orphan children aged 0-18 years. Started in 1978, the scheme aims to offer a domestic environment for orphan children, with financial assistance increasing over the years. Foster parents must meet income criteria, and specific do

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Addressing the communication gap is crucial in bridging the educational disparity between disadvantaged and privileged children. The initiative focuses on enhancing language skills, adult-child interactions, and early literacy through evidence-based strategies and activities. Training sessions aim t

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Marketers target children through advertising due to their influence on purchasing decisions and future consumer behavior. The use of various techniques, such as celebrity endorsements and comparisons, can impact children's preferences, behaviors, and health choices. Researchers express concerns abo

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The Government of Liberia's COVID-19 Household Food Support Programme aims to assist those facing food insecurity in four target counties. Using data from various assessments, the programme estimates a caseload of 1,971,000 individuals. Targeting strategies include geographical and household-level c

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The year 2019 marked significant milestones for child rights advocacy with the launch of the Child Rights Now Flagship Report and the 30th Anniversary of the UN Convention on the Rights of the Child. Organizations like ChildFund Alliance, Plan International, Save the Children, SOS Children's Village

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This presentation provides information on domestic abuse, its impact on children and young people, signs of abuse, and the role of adults in supporting learners in educational settings in Scotland. It highlights the prevalence of domestic abuse, defines what domestic abuse is, explores how children

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The Citizen Security and Justice Programme (CSJP) under the Ministry of National Security in Jamaica focuses on violence prevention through case management, risk assessment, and treatment plans. By targeting at-risk youth and implementing services such as education, psychological support, and peer a

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Children and young people up to 18 years are entitled to rights under the United Nations Convention of the Rights of the Child (UNCRC). This agreement aims to protect children and ensure they are happy, healthy, and safe. It covers topics such as the role of the Children's Commissioner for Wales, Sa

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Depression and anxiety in children are serious mental health concerns that can impact their daily functioning and overall well-being. Childhood depression, if left untreated, can lead to long-term consequences. Recognizing the signs and symptoms of depression in children, such as irritability, socia

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Openly discussing the coronavirus with children is essential to alleviate worries and provide accurate information. Parents should filter news, offer developmentally appropriate responses, and take cues from children's questions. It's crucial to manage parental anxiety, reassure children about the v

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Uganda has successfully implemented an Assisted Partner Notification (APN) program to reach men for HIV testing, addressing the gender gap in testing rates. By utilizing various approaches such as index testing, self-testing, and social network testing, Uganda has achieved significant success in tar

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In today's digital age, children are growing up with easy access to technology, shaping their future employment prospects and educational experiences. Studies show a significant increase in screen time for young children, with a rise in the use of tablets and computers from a very young age. Despite

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The National Shelter and Non-Food Items Cluster meeting in Iraq on Wednesday, 24th September 2014 discussed various important agenda items including updates on the SRP process, strategic objectives, overview of cluster projects, types of assistance provided, and targeting vulnerable groups. A total

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Jennett's Park CE Primary School is committed to educating children for wisdom, knowledge, and skills, while fostering hope, aspiration, community, dignity, and respect. Through a multi-cultural, inclusive approach, the school aims to empower children to flourish under God's love, helping them grow

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This seminar focuses on common scams targeting Licensed Professional Counselors, including phishing, Canadian, limo driver, and sheriff scams, social media scams, and fake tech support. Presented by industry experts, it provides insights on recognizing red flags, avoiding scams, and steps to take if

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GIRFEC (Getting It Right For Every Child) is a national children's rights-based approach aimed at improving outcomes from early intervention to child protection. It involves embedding culture, systems, and practice changes to ensure children receive the help they need when they need it. Every child

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Children are considered vulnerable consumers due to undeveloped executive functions like inhibitory control and cognitive flexibility. They struggle to differentiate between commercials and TV programs, making them susceptible to marketing strategies targeting them with food/beverage products. Marke

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This research roundtable delves into the impact of food advertising and marketing on children and youths as part of the Bridging the Gap program. The collaborative effort assesses various health-related behaviors influenced by policies, programs, and environmental factors, including adolescent eatin

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Presenting research results on enhancing children's agency and hybrid integration through dialogic interactions in school settings, specifically focusing on children with migrant backgrounds. The project aims to propose effective facilitation methods to support the participation of children with mig

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Children living with parental alcohol problems often face challenges that can have lasting effects on their well-being. This seminar highlights the need for support and courage for these children and discusses the implications for practitioners. It also sheds light on the hidden population of childr

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Healthy Eating Research Program, launched in 2005, focuses on preventing childhood obesity by targeting children, adolescents, and families. The program aims to establish a research base on factors influencing healthy eating and body weight in children, build a multidisciplinary research field, and

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This study explores phonological impairment in French-speaking children with SLI, confirming specific difficulties in phonology compared to age-matched peers and across different languages. Evidence suggests phonological delays and deficits, with stronger evidence found through comparison with MLU-m

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The initiative focuses on implementing the Children's Right to Food Charter to combat food poverty among vulnerable children. It includes introducing projects like the Children's Right to Food Project in partnership with schools and community organizations. Key aspects involve improving access to nu

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The World Bank and UNHCR collaborate to enhance the effectiveness of assisting Syrian refugees by leveraging survey data to optimize targeting strategies for cash assistance programs. By combining registry and survey information, the study aims to identify the best welfare and poverty indicators, ul

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IFAD independent evaluations play a crucial role in ensuring that vulnerable groups are not left behind in rural development initiatives. By assessing the effectiveness of targeting methods, documenting instances where vulnerable groups are excluded, and providing recommendations for improvement, th

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The State of Nevada's ATAP program, overseen by Governor Brian Sandoval and Director Richard Whitley, assists children with autism by providing comprehensive services. The program currently serves a caseload of 698 active children with an average age of 9.477. However, there are still 477 children w

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Supplementary data from RadioGauge reveals interesting patterns in young listeners aged 4-16. Findings show an increase in radio listening as children grow older, with higher rates among children of CR listener parents. The study also highlights locations where children listen and the prevalence of

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Inflation targeting emphasizes clear communication with the public and financial markets, enhancing transparency and accountability in monetary policy. By setting explicit inflation targets, central banks improve public understanding, encourage debate, and increase the accountability of policy-maker

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Explore the fundamentals of direct work with children and young people in the Newham Children Services Practitioners Workshop 2020. Discover the purpose, planning, and application of direct work, focusing on outcomes and challenges. Learn to apply a systemic and restorative approach, utilizing solut

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